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1. 发明授权

US07013637B2 Exhaust purification apparatus and method for internal combustion engine 失效
标题翻译：内燃机排气净化装置及方法
公开(公告)号：US07013637B2
公开(公告)日：2006-03-21
申请号：US10609627
申请日：2003-07-01
申请人： Iwao Yoshida
发明人： Iwao Yoshida
IPC分类号： F01N3/00
CPC分类号： F02D41/1463 , F02D37/02 , F02D41/0245 , F02D41/027 , F02D41/402 , F02D2200/0802 , F02P5/1502 , Y02T10/26 , Y02T10/44
摘要： In exhaust purification apparatus and method for an internal combustion engine having an exhaust gas purification catalyst disposed in an exhaust passage of the engine, a poisoning release control of the exhaust gas purification catalyst is executed when a predetermined condition is established, the poisoning release control including a normal mode and an exhaust gas composition mode before the normal mode, and a manipulation parameter (for example, an ignition timing) of the engine related to an exhaust gas composition is manipulated in such a manner that a hydrogen concentration in the exhaust gas in the exhaust gas composition mode is higher than that in the normal mode.
摘要翻译：在具有设置在发动机的排气通路中的排气净化催化剂的内燃机的排气净化装置和方法中，当建立预定条件时执行废气净化催化剂的中毒释放控制，所述中毒释放控制包括在正常模式之前的正常模式和排气组成模式以及与废气组成相关的发动机的操作参数（例如点火正时）被操作，使得废气中的氢浓度在废气组成模式高于正常模式。

2. 发明授权

US06708668B2 Control system and method for direct-injection spark-ignition engine 失效
标题翻译：直喷式点火发动机的控制系统及方法
公开(公告)号：US06708668B2
公开(公告)日：2004-03-23
申请号：US10176189
申请日：2002-06-21
申请人： Iwao Yoshida , Takao Maitani
发明人： Iwao Yoshida , Takao Maitani
IPC分类号： F02D4130
CPC分类号： F02D41/3029 , F02D37/02 , F02D41/307 , F02D41/403 , F02D2250/28 , F02P5/1502 , F02P5/1504 , Y02T10/44 , Y02T10/46
摘要： A control system for a direct-injection spark-ignition internal combustion engine is provided which includes a first control section for switchably controlling a combustion mode between a homogeneous combustion mode and a stratified stoichiometric combustion mode, and a second control section for advancing, at a time of switching from the homogeneous combustion mode to the stratified stoichiometric combustion mode, an ignition timing by an amount for offsetting a variation of torque simultaneously with switching of the combustion mode, gradually retarding the ignition timing after the switching of the combustion mode, and after the ignition timing has retarded a predetermined amount, retarding a compression stroke fuel injection timing in the stratified combustion mode while retarding the ignition timing further. A control method is also provided.
摘要翻译：提供了一种用于直喷火花点火内燃机的控制系统，其包括用于可切换地控制均匀燃烧模式和分层化学计量燃烧模式之间的燃烧模式的第一控制部分，以及用于在从均匀燃烧模式切换到分层化学计量燃烧模式的时间，点火正时与燃烧模式切换同时抵消转矩变化的量，逐渐延迟燃烧模式切换之后的点火正时，以及之后点火正时已经延迟了预定量，延迟了分层燃烧模式中的压缩行程燃料喷射正时，同时进一步延迟点火正时。还提供了一种控制方法。

3. 发明授权

US06217872B1 Non-A, non-B hepatitis virus genomic cDNA and antigen polypeptide 失效
标题翻译：非A型，非乙型肝炎病毒基因组cDNA和抗原多肽
公开(公告)号：US06217872B1
公开(公告)日：2001-04-17
申请号：US09315850
申请日：1999-05-21
申请人： Hiroto Okayama , Isao Fuke , Chisato Mori , Akihisa Takamizawa , Iwao Yoshida
发明人： Hiroto Okayama , Isao Fuke , Chisato Mori , Akihisa Takamizawa , Iwao Yoshida
IPC分类号： A61K3929
CPC分类号： C07K14/005 , A61K39/00 , C12N2770/24222 , Y10S930/223
摘要： Disclosed is an isolated non-A, non-B hepatitis virus genomic CDNA covering the entire region of the virus gene nucleotide sequence from the 1st to 9416th nucleotides shown in FIG. 2(1) through FIG. 2(16) hereof, wherein the coding region is from the 333rd to 9362nd nucleotides, and the 5′- and 3′-noncoding sequences contain 332 nucleotides and 54 nucleotides, respectively. Part of the cDNA and an antigen polypeptide as an expression product thereof are useful as a diagnostic reagent for non-A, non-B hepatitis. The antigen polypeptide is also useful as an active ingredient for a non-A, non-B hepatitis virus vaccine.
摘要翻译：公开了一种分离的非A非乙型肝炎病毒基因组CDNA，其覆盖图1所示的第1至第9416位核苷酸的病毒基因核苷酸序列的整个区域。图2（1）〜图 2（16），其中编码区为333〜9362个核苷酸，5'-和3'-非编码序列分别含有332个核苷酸和54个核苷酸。作为其表达产物的cDNA和抗原多肽的一部分可用作非A非乙型肝炎的诊断试剂。抗原多肽也可用作非A非乙型肝炎病毒疫苗的活性成分。

4. 发明授权

US05998130A Non-A, non-B hepatitis virus genomic cDNA and antigen polypeptide 失效
标题翻译：非A型，非乙型肝炎病毒基因组cDNA和抗原多肽
公开(公告)号：US05998130A
公开(公告)日：1999-12-07
申请号：US904686
申请日：1997-08-01
申请人： Hiroto Okayama , Isao Fuke , Chisato Mori , Akihisa Takamizawa , Iwao Yoshida
发明人： Hiroto Okayama , Isao Fuke , Chisato Mori , Akihisa Takamizawa , Iwao Yoshida
IPC分类号： A61K39/00 , C07K14/18 , C12N15/40 , C12Q1/70
CPC分类号： C07K14/005 , A61K39/00 , C12N2770/24222 , Y10S930/223
摘要： Disclosed is an isolated non-A, non-B hepatitis virus genomic cDNA covering the entire region of the virus gene nucleotide sequence from the 1st to 9416th nucleotides shown in FIG. 2(1) through FIG. 2(16) hereof, wherein the coding region is from the 333rd to 9362nd nucleotides, and the 5'- and 3'- noncoding sequences contain 332 nucleotides and 54 nucleotides, respectively. Part of the cDNA and an antigen polypeptide as an expression product thereof are useful as a diagnostic reagent for non-A, non-B hepatitis. The antigen polypeptide is also useful as an active ingredient for a non-A, non-B hepatitis virus vaccine.
摘要翻译：公开了一种分离的非A非乙型肝炎病毒基因组cDNA，其覆盖图1所示的第1至第9416位核苷酸的病毒基因核苷酸序列的整个区域。图2（1）〜图 2（16），其中编码区是从333到9362个核苷酸，5'-和3'-非编码序列分别含有332个核苷酸和54个核苷酸。作为其表达产物的cDNA和抗原多肽的一部分可用作非A非乙型肝炎的诊断试剂。抗原多肽也可用作非A非乙型肝炎病毒疫苗的活性成分。

5. 发明授权

US5139776A Method for culturing Bordetella pertussis, a pertussis toxoid and a pertussis vaccine 失效
标题翻译：培养百日咳博德特氏菌，百日咳类毒素和百日咳疫苗的方法
公开(公告)号：US5139776A
公开(公告)日：1992-08-18
申请号：US305680
申请日：1989-02-03
申请人： Masashi Chazono , Iwao Yoshida , Takeo Konobe , Juichiro Osame , Keisuke Takaku
发明人： Masashi Chazono , Iwao Yoshida , Takeo Konobe , Juichiro Osame , Keisuke Takaku
IPC分类号： A61K39/10 , C12N1/20
CPC分类号： C12N1/20 , A61K39/099 , Y10S435/832
摘要： There is disclosed a method for culturing Bordetella pertussis in the presence of a cellulose and/or cellulose derivatives. The present method is useful for obtaining a mixed antigen comprising pertussis toxin and filamentous hemagglutinin in a large amount at low cost. From the antigen, there can be obtained a stable and effective pertussis toxoid to be used for a pertussis vaccine. There is also disclosed a vaccine comprising the pertussis toxoid as an active ingredient and a gelatin and/or gelatin derivatives as a stabilizing agent. The present vaccine is extremely stable and can be stored for a prolonged period of time.
摘要翻译：公开了一种在纤维素和/或纤维素衍生物存在下培养百日咳博德特氏菌的方法。本方法以低成本大量获得包含百日咳毒素和丝状血凝素的混合抗原是有用的。从抗原中可获得用于百日咳疫苗的稳定且有效的百日咳类毒素。还公开了包含百日咳类毒素作为活性成分的疫苗和明胶和/或明胶衍生物作为稳定剂。目前的疫苗非常稳定，可以长时间保存。

6. 发明授权

US4849358A Method for culturing bordetella pertussis, a pertussis toxoid and a pertussis vaccine 失效
标题翻译：培养百日盛博戈特氏菌的方法，百日咳类毒素和百日咳疫苗
公开(公告)号：US4849358A
公开(公告)日：1989-07-18
申请号：US073134
申请日：1987-07-14
申请人： Masashi Chazono , Iwao Yoshida , Takeo Konobe , Juichiro Osame , Keisuke Takaku
发明人： Masashi Chazono , Iwao Yoshida , Takeo Konobe , Juichiro Osame , Keisuke Takaku
IPC分类号： A61K39/00 , A61K39/10 , C07K14/235 , C12N1/20 , C12N1/22
CPC分类号： C12N1/22 , A61K39/099 , C07K14/235 , C12N1/20 , A61K39/00 , Y10S435/832
摘要： There is disclosed a method for culturing Bordetella pertussis in the prece of a cellulose and/or cellulose derivatives. The present method is useful for obtaining a mixed antigen comprising pertussis toxin and filamentous hemagglutinin in a large amount at low cost. From the antigen, there can be obtained a stable and effective pertussis toxoid to be used for a pertussis vaccine. There is also disclosed a vaccine comprising the pertussis toxoid as an active ingredient and a gelatin and/or gelatin derivatives as a stabilizing agent. The present vaccine is extremely stable and can be stored for a prolonged period of time.
摘要翻译：公开了一种在纤维素和/或纤维素衍生物存在下培养百日咳博德特氏菌的方法。本方法以低成本大量获得包含百日咳毒素和丝状血凝素的混合抗原是有用的。从抗原中可获得用于百日咳疫苗的稳定且有效的百日咳类毒素。还公开了包含百日咳类毒素作为活性成分的疫苗和明胶和/或明胶衍生物作为稳定剂。目前的疫苗非常稳定，可以长时间保存。

7. 发明授权

US4810492A Flavivirus antigen 失效
标题翻译：黄病毒抗原
公开(公告)号：US4810492A
公开(公告)日：1989-03-07
申请号：US932419
申请日：1986-11-19
申请人： Hiroyuki Fujita , Iwao Yoshida , Mitsuo Takagi , Sadao Manabe , Konosuke Fukai
发明人： Hiroyuki Fujita , Iwao Yoshida , Mitsuo Takagi , Sadao Manabe , Konosuke Fukai
IPC分类号： A61K39/12 , A61K39/00 , C07K14/00 , C07K14/18 , C12N15/00 , C12N15/09 , C12P21/02 , C12R1/865 , C12R1/91 , A61K37/02 , C07K13/00
CPC分类号： C07K14/005 , A61K39/00 , C12N2770/24122
摘要： There is disclosed an antigen comprising at least part of an amino acid sence of the antigen of a flavivirus, which part contains at least one of epitopes of the flavivirus antigen. The present antigen can be produced easily and safely at low cost by means of recombinant DNA technique. The present antigen can be used as an effective vaccine and diagnostic for Japanese encephalitis.
摘要翻译：公开了包含至少部分黄病毒抗原的氨基酸序列的抗原，该部分含有黄病毒抗原的表位中的至少一个。本发明的抗原可以通过重组DNA技术以低成本容易且安全地生产。本抗原可用作日本脑炎的有效疫苗和诊断。

8. 发明授权

US4519963A Electroconductive cross-linked polyolefin foam and method for manufacture thereof 失效
标题翻译：导电交联聚烯烃泡沫及其制造方法
公开(公告)号：US4519963A
公开(公告)日：1985-05-28
申请号：US495406
申请日：1983-05-17
申请人： Iwao Yoshida , Takeo Kasanami , Shuji Miura
发明人： Iwao Yoshida , Takeo Kasanami , Shuji Miura
IPC分类号： C08J9/06 , B29C44/00 , C08J9/00 , C08K3/04 , H01B1/24 , B29J1/02
CPC分类号： C08J9/0066 , B29C44/00 , C08K3/04 , H01B1/24 , B29K2023/00 , B29K2105/04 , B29K2105/24 , C08J2323/02 , Y10S264/18 , Y10S521/915
摘要： An electroconductive cross-linked polyolefin foam having electric resistance of not more than 100 M.OMEGA. and comprising uniform minute cells and proving useful for the production of IC cases, etc. is provided by a method which comprises kneading 100 parts by weight of a polyolefin, 10 to 30 parts by weight of carbon particles, and suitable amounts of a foaming agent and a cross-linking agent and heating the resultant cross-linkable and foamable composition under atmospheric pressure thereby allowing the composition to be cross-linked and foamed without being abruptly foamed or expanded or by a method which comprises heating the aforementioned cross-linkable and foamable composition in a metal mold under pressure to a temperature at which the foaming agent is not substantially decomposed thereby cross-linking the composition and then heating the resultant cross-linked foamable composition under atmospheric pressure thereby allowing the composition to be foamed without being abruptly foamed or expanded. The aforementioned cross-linking may be effected by irradiation of the composition with an electron beam.
摘要翻译：通过包括捏合100重量份的聚烯烃的方法，提供具有不超过100M欧米茄并且包含均匀的微细胞并证明用于制造IC盒等的导电交联聚烯烃泡沫体， 10〜30重量份的碳颗粒和适量的发泡剂和交联剂，并在大气压下加热所得的可交联和可发泡组合物，从而允许组合物交联和发泡而不突然发泡或膨胀的方法，或通过将金属模具中的上述可交联和可发泡组合物在压力下加热至发泡剂基本上不分解的温度，从而交联组合物，然后加热所得交联剂可发泡组合物，从而允许组合物发泡而不会突然发生 amed或扩大。上述交联可以通过用电子束照射组合物来实现。

9. 发明授权

US06561158B2 Enhanced engine response to torque demand during cold-start and catalyst warm-up 有权
公开(公告)号：US06561158B2
公开(公告)日：2003-05-13
申请号：US09982097
申请日：2001-10-19
申请人： Iwao Yoshida , Takao Maitani
发明人： Iwao Yoshida , Takao Maitani
IPC分类号： F02B1700
CPC分类号： F02P5/1504 , F02B2075/125 , F02D37/02 , F02D41/0255 , F02D41/3023 , F02D41/3029 , F02D41/307 , F02D41/402 , Y02T10/123 , Y02T10/128 , Y02T10/26 , Y02T10/46
摘要： A spark ignited internal combustion engine employs fuel injectors positioned to inject fuel directly into combustion chambers of the engine, and an electronic engine controller (EEC) to control operation of the engine. The EEC implements a routine which controls the quantity of fuel injected, and spark timing by varying a period of time, which is required for advancing the spark timing during switch from a stratified stoichiometric charge combustion by split injection to a homogeneous charge combustion by single injection, with differing degrees of operator torque demand.

10. 发明授权

US06543220B2 Exhaust emission control apparatus of internal combustion engine 有权
标题翻译：内燃机废气排放控制装置
公开(公告)号：US06543220B2
公开(公告)日：2003-04-08
申请号：US09741839
申请日：2000-12-22
申请人： Iwao Yoshida , Tsutomu Kikuchi
发明人： Iwao Yoshida , Tsutomu Kikuchi
IPC分类号： F01N300
CPC分类号： F02D41/042 , F02D41/062 , F02D41/1441 , F02D2200/503 , Y02T10/42
摘要： In an exhaust emission control apparatus of an internal combustion engine with an intake air flow control valve controlling intake air flow exerting an influence upon a behavior of fuel injected from a fuel injector, and an electric valve actuator electrically operated by a storage battery serving as an electric power source to drive the intake air flow control valve, an electronic control unit is provided for controlling an opening of the intake air flow control valve. The control unit controls the opening of the intake air flow control valve to a predetermined intermediate valve opening by the valve actuator during an engine stopping period. Also, the control unit holds the intake air flow control valve at the predetermined intermediate valve opening to which the intake air flow control valve has been driven in advance during the engine stopping period, by inhibiting operation of the valve actuator during an engine-cranking operating mode at a starting period.
摘要翻译：在具有进气流量控制阀的内燃机的废气排放控制装置中，所述进气流量控制阀控制对从燃料喷射器喷射的燃料的行为产生影响的进气流，以及由作为用于驱动进气流量控制阀的电源，设置有用于控制进气流量控制阀的打开的电子控制单元。控制单元在发动机停止期间通过阀致动器控制进气流量控制阀的打开到预定的中间阀开度。此外，控制单元通过在发动机起动操作期间禁止阀致动器的操作将进气流量控制阀保持在在发动机停止期间预先被驱动的进气流量控制阀的预定中间阀开口模式在开始的时期。

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