专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2009145349A1 DETECTION METHOD USING NUCLEIC ACID ARRAY 审中-公开
标题翻译：使用核酸序列的检测方法
公开(公告)号：WO2009145349A1
公开(公告)日：2009-12-03
申请号：PCT/JP2009/060103
申请日：2009-05-27
申请人： FUJIFILM Corporation , National University Corporation Tokyo Medical and Dental University , ISHII, Yasuyuki , INAZAWA, Johji , IMOTO, Issei
发明人： ISHII, Yasuyuki , INAZAWA, Johji , IMOTO, Issei
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6837 , C12Q2545/101 , C12Q2563/107
摘要： A method of comparing a first nucleic acid sequence of a first cell or cell population with a second nucleic acid sequence of a second cell or cell population, includes: a) labeling the first and second nucleic acid sequences with the same label; b) adding the labeled first and second nucleic acid sequences to separate first and second reaction fields respectively, the first and second reaction fields being provided at a nucleic acid array equipped with a plurality of reaction fields, and carrying out hybridization; c) subjecting the first and second reaction fields to the same washing operation by carrying out the washing operation in the identical liquid bath so as to uniform washing conditions; and d) detecting first and second signals at the first and second reaction fields respectively, and comparing obtained signal intensities of the first and second signals between the first and second reaction fields.
摘要翻译：比较第一细胞或细胞群体的第一核酸序列与第二细胞或细胞群体的第二核酸序列的方法包括：a）用相同标记物标记第一和第二核酸序列; b）分别添加标记的第一和第二核酸序列以分离第一和第二反应场，第一和第二反应场在配备有多个反应场的核酸阵列上提供，并进行杂交; c）通过在相同的液浴中进行洗涤操作以使均匀的洗涤条件使第一和第二反应场进行相同的洗涤操作; 以及d）分别在第一和第二反应场检测第一和第二信号，并且比较所获得的第一和第二反应场之间的第一和第二信号的信号强度。

2. 发明申请

WO2009145346A3 METHOD FOR ANALYSIS USING NUCLEIC ACID MICROARRAY 审中-公开
公开(公告)号：WO2009145346A3
公开(公告)日：2009-12-03
申请号：PCT/JP2009/060098
申请日：2009-05-27
申请人： FUJIFILM CORPORATION , NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY , UJIHARA, Dai , KANEHARA, Hideyuki , INAZAWA, Johji , IMOTO, Issei
发明人： UJIHARA, Dai , KANEHARA, Hideyuki , INAZAWA, Johji , IMOTO, Issei
IPC分类号： C12Q1/68
摘要： An analytical method aided with a nucleic acid microarray, the nucleic acid microarray having a spot (X 1) onto which a first probe nucleic acid is immobilized, the method includes: allowing a labeled sample nucleic acid (A 1) of a sample to be tested to hybridize with the first probe nucleic acid; providing the spot (X 1) with a labeled verification nucleic acid (B) that has a sequence capable of hybridizing with at least a part of the first probe nucleic acid and is labeled with a label different from the labeled sample nucleic acid (A 1), and allowing the labeled verification nucleic acid (B) to hybridize with at least the first probe nucleic acid at all spots; measuring a labeled quantity value (F 1) of the labeled sample nucleic acid (A 1); and measuring a labeled quantity value (Fc 1) of the labeled verification nucleic acid (B).

3. 发明申请

WO2009145346A2 METHOD FOR ANALYSIS USING NUCLEIC ACID MICROARRAY 审中-公开
标题翻译：使用核酸微量分析的方法
公开(公告)号：WO2009145346A2
公开(公告)日：2009-12-03
申请号：PCT/JP2009060098
申请日：2009-05-27
申请人： FUJIFILM CORP , NAT UNIV CORP TOKYO MED & DENT , UJIHARA DAI , KANEHARA HIDEYUKI , INAZAWA JOHJI , IMOTO ISSEI
发明人： UJIHARA DAI , KANEHARA HIDEYUKI , INAZAWA JOHJI , IMOTO ISSEI
CPC分类号： C12Q1/6837 , G01N33/582 , C12Q2545/101
摘要： An analytical method aided with a nucleic acid microarray, the nucleic acid microarray having a spot (X 1) onto which a first probe nucleic acid is immobilized, the method includes: allowing a labeled sample nucleic acid (A 1) of a sample to be tested to hybridize with the first probe nucleic acid; providing the spot (X 1) with a labeled verification nucleic acid (B) that has a sequence capable of hybridizing with at least a part of the first probe nucleic acid and is labeled with a label different from the labeled sample nucleic acid (A 1), and allowing the labeled verification nucleic acid (B) to hybridize with at least the first probe nucleic acid at all spots; measuring a labeled quantity value (F 1) of the labeled sample nucleic acid (A 1); and measuring a labeled quantity value (Fc 1) of the labeled verification nucleic acid (B).
摘要翻译：一种利用核酸微阵列辅助的分析方法，所述核酸微阵列具有固定有第一探针核酸的点（X 1），所述方法包括：使样品的标记样品核酸（A 1）为测试与第一探针核酸杂交; 向斑点（X 1）提供具有能够与至少一部分第一探针核酸杂交的序列并用不同于标记的样品核酸（A 1）标记的标记的核酸核酸（B）），并且允许标记的验证核酸（B）在所有点与至少第一探针核酸杂交; 测量标记的样品核酸（A 1）的标记量值（F 1）; 并测量标记的验证核酸（B）的标记量值（Fc 1）。

4. 发明申请

WO2009145355A1 METHOD FOR MEASURING NUCLEIC ACID USING NUCLEIC ACID MICROARRAY 审中-公开
标题翻译：使用核酸微量测定核酸的方法
公开(公告)号：WO2009145355A1
公开(公告)日：2009-12-03
申请号：PCT/JP2009/060208
申请日：2009-05-28
申请人： FUJIFILM Corporation , National University Corporation Tokyo Medical and Dental University , KANEHARA, Hideyuki , INAZAWA, Johji , IMOTO, Issei
发明人： KANEHARA, Hideyuki , INAZAWA, Johji , IMOTO, Issei
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6837 , C12Q2545/101
摘要： A method for measuring a target nucleic acid includes: labeling one target nucleic acid with at least two labeling reagents to prepare a labeled target nucleic acid; allowing the labeled target nucleic acid to hybridize with a probe nucleic acid on a nucleic acid microarray; reading labeled amounts obtained from the respective at least two labeling reagents of the hybridized nucleic acid; and averaging the labeled amounts to obtain an average value of the labeled amounts.
摘要翻译：用于测量靶核酸的方法包括：用至少两种标记试剂标记一个靶核酸以制备标记的靶核酸; 使标记的靶核酸与核酸微阵列上的探针核酸杂交; 读取从杂交核酸的相应的至少两种标记试剂获得的标记量; 并平均该标记量以获得标记量的平均值。

5. 发明申请

US20050037345A1 Gasci gene 有权
标题翻译：加西氏基因
公开(公告)号：US20050037345A1
公开(公告)日：2005-02-17
申请号：US10311002
申请日：2001-06-12
申请人： Johji Inazawa , Imoto Issei
发明人： Johji Inazawa , Imoto Issei
IPC分类号： C12N15/09 , A61K39/395 , A61K48/00 , A61P35/00 , C07K14/82 , C07K16/32 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/12 , C12P21/02 , C12P21/08 , C12Q1/68 , C07H21/04 , C12N9/16
CPC分类号： C07K14/82
摘要： The invention provides, for example, a gene comprising a polynucleotide coding for the polypeptide having the amino acid sequence shown in SEQ ID NO:3. The gene shows amplification in the 9p23-24 region, has a PX domain and PHD finger motifs, plays an important role in cell growth and differentiation, and in tumorigenesis, and is useful in elucidating the pathology of various diseases caused by a protein involved in cell differentiation in malignant tumor or the like, and in the diagnosis and treatment of such diseases.
摘要翻译：本发明提供了例如包含编码具有SEQ ID NO：3所示的氨基酸序列的多肽的多核苷酸的基因。该基因显示在9p23-24区域的扩增，具有PX结构域和PHD指纹基序，在细胞生长和分化以及肿瘤发生中起重要作用，可用于阐明涉及到的蛋白质引起的各种疾病的病理学恶性肿瘤等中的细胞分化，以及这些疾病的诊断和治疗。

6. 发明授权

US07105649B2 Gasci gene 有权
标题翻译：加西氏基因
公开(公告)号：US07105649B2
公开(公告)日：2006-09-12
申请号：US10311002
申请日：2001-06-12
申请人： Inazawa Johji , Imoto Issei
发明人： Inazawa Johji , Imoto Issei
IPC分类号： C07H21/04
CPC分类号： C07K14/82
摘要： The invention provides, for example, a gene comprising a polynucleotide coding for the polypeptide having the amino acid sequence shown in SEQ ID NO:3. The gene shows amplification in the 9p23-24 region, has a PX domain and PHD finger motifs, plays an important role in cell growth and differentiation, and in tumorigenesis, and is useful in elucidating the pathology of various diseases caused by a protein involved in cell differentiation in malignant tumor or the like, and in the diagnosis and treatment of such diseases.
摘要翻译：本发明提供了例如包含编码具有SEQ ID NO：3所示的氨基酸序列的多肽的多核苷酸的基因。该基因显示在9p23-24区域的扩增，具有PX结构域和PHD指纹基序，在细胞生长和分化以及肿瘤发生中起重要作用，可用于阐明涉及到的蛋白质引起的各种疾病的病理学恶性肿瘤等中的细胞分化，以及这些疾病的诊断和治疗。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式