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    • 1. 发明授权
    • Coagulation timer
    • 凝血定时器
    • US5613491A
    • 1997-03-25
    • US563369
    • 1995-11-28
    • Rowland W. KannerFred E. Williams, Jr.
    • Rowland W. KannerFred E. Williams, Jr.
    • A61B5/145A61B10/00A61F13/38A61B5/00
    • A61B5/02042A61B10/00A61F13/38Y10S128/22
    • A coagulation timer device is used to monitor the bleeding time of a patient to determine the amount of time required to achieve clotting. The coagulation timer device includes a carrier member, a linearly oriented absorbing medium which is affixed to the carrier member and a bag member which overlays the carrier member and the medium. The medium, such as filter paper or the like, is used to blot blood from an incision which has been formed through the skin. The medium is affixed to the carrier member and includes a plurality of segments each of which are defined by a scalloped edge portion which extends beyond the edges of the carrier member. The segments are used one at a time at predetermined intervals to blot the blood by touching the scalloped edge to the blood. Indicia is provided on the carrier member to let a medical person or technician know where the medium should be touched to the blood at each predetermined interval and provides a quick reference guide to let the technician know the amount of time that it has taken for the blood to clot. The bag member is affixed to the carrier member and is retractable to uncover the medium, while being replaceable to cover the medium.
    • 凝血定时器装置用于监测患者的出血时间以确定实现凝血所需的时间量。 凝固定时装置包括承载构件,固定在承载构件上的直线吸收介质和覆盖载体构件和介质的袋构件。 介质如滤纸等用于从通过皮肤形成的切口上吸印血液。 介质固定在承载构件上,并且包括多个段,每个段由扇形边缘部分限定,该扇形边缘部分延伸超过载体构件的边缘。 这些片段以预定间隔一次一个地使用,以通过将扇形边缘触及血液来吸印血液。 在承运人成员上提供标记,以让医疗人员或技术人员以每个预定间隔知道介质应该接触血液的位置,并提供快速参考指南,让技术人员知道其为血液所采取的时间量 凝结 袋构件被固定到承载构件上并且可缩回以露出介质,同时可更换以覆盖介质。
    • 3. 发明授权
    • Stent compression instrument
    • 支架压缩仪
    • US5746764A
    • 1998-05-05
    • US745317
    • 1996-11-12
    • Nicholas A. GreenFred E. Williams, Jr.
    • Nicholas A. GreenFred E. Williams, Jr.
    • A61F2/06A61F2/84A61M29/00
    • A61F2/958A61F2002/9522
    • In accordance with the present invention, a fluid compression instrument and method for particular use in pre-surgically securing and conforming a vascular stent upon an angioplasty balloon, includes a housing for containing pressurized fluid and an elastic enclosing diaphragm secured within the housing and having an internal cavity and opening arranged to receive the stent disposed on the balloon catheter for secured compression. A pressure chamber is arranged within the housing as an envelope about the diaphragm to enable pressurized fluid forces within the pressure chamber to be imposed upon the outer surface of the diaphragm and transmitted through the diaphragm enabling circumferential application against the inserted stent in order uniformly to compress the stent with correspondingly secured purchase against the deflated balloon surface, producing complete adhesion of the stent thereon. The subsequent balloon inflation angioplasty and stent expansion is not impaired since the balloon remains in its deflated shape with the compressed stent closely conforming in contour throughout the balloon's 360.degree. periphery. The entire stent mesh is uniformly compressed down including the open stent ends which prevents the many tiny stent mesh edges from protruding out and effectively prevents both vascular abrasion as well as shifting of the stent on the deflated balloon during the angioplasty insertion procedure.
    • 根据本发明,特别用于在血管成形术球囊上手术前固定和符合血管支架的流体压缩仪器和方法包括用于容纳加压流体的壳体和固定在壳体内的弹性封闭隔膜, 内腔和开口布置成接纳设置在球囊导管上的支架,用于固定压缩。 压力室在壳体内作为围绕隔膜的信封布置,以使得压力室内的加压流体力能够施加在隔膜的外表面上,并且透过隔膜使得能够周向地施加抵靠插入的支架以均匀地压缩 所述支架相对于所述放气球囊表面具有相应的固定购买,从而在其上产生支架的完全粘附。 随后的球囊充气血管成形术和支架扩张不受损害,因为气囊保持其缩小的形状,压缩的支架在整个气球的360°周边处具有紧密的轮廓。 整个支架网均匀压缩,包括开放的支架末端,其防止许多微小的支架网边缘突出,并且在血管成形术插入过程期间有效地防止血管磨损以及支架在放气球囊上的移位。
    • 5. 发明授权
    • Stent holder/compression instrument
    • 支架/压缩仪器
    • US5972028A
    • 1999-10-26
    • US6748
    • 1998-01-13
    • Richard RabenauRowland W. KannerFred E. Williams, Jr.
    • Richard RabenauRowland W. KannerFred E. Williams, Jr.
    • A61F2/00A61F2/06A61F2/84
    • A61F2/0095A61F2/958A61F2002/9522
    • A novel stent compression instrument is used for holding a stent therein during shipping to a hospital and for thereafter crimping the stent onto a balloon catheter. The stent compression instrument includes a body having a central bore; a flexible diaphragm having an axial lumen and mounted within the body central bore, thereby defining a chamber between the body and the diaphragm, and first and second sealing structures for providing seals at opposite ends of the chamber. The diaphragm is formed from a generally tubular, thin wall into which the stent is placed therein and is expandable under a negative pressure condition to expand within the body and compressible under pressure to crimp the stent onto a balloon catheter. Holding structure, which is formed from at least one thickened wall portion along the length of the diaphragm wall, is associated with the diaphragm for holding the stent therewithin and to prevent movement of the stent once positioned therewithin when the diaphragm is subjected to a negative pressure condition. In the preferred embodiment, positioning structure is provided which is formed from a thickened wall portion along the length of the diaphragm wall which is spaced from the holding structure, is also associated with the diaphragm for positioning the stent within the lumen and preventing the further axial movement of the stent relative to the lumen when the stent is placed therein.
    • 一种新型的支架压缩仪器用于在运送到医院期间将支架保持在其中,并且此后将支架压接到球囊导管上。 支架压缩仪器包括具有中心孔的主体; 柔性膜片,其具有轴向内腔并且安装在主体中心孔内,从而在主体和隔膜之间限定腔室,以及用于在腔室的相对端处提供密封的第一和第二密封结构。 隔膜由通常管状的薄壁形成,支架置于其中,并且在负压条件下可膨胀,以在体内膨胀并在压力下压缩以将支架卷曲到球囊导管上。 由沿着隔膜壁的长度的至少一个加厚的壁部分形成的保持结构与用于在其中保持支架的隔膜相关联,并且防止一旦定位在支架上,当隔膜受到负压时 条件。 在优选实施例中,提供了定位结构,其由沿着与保持结构间隔开的隔膜壁的长度的增厚壁部分形成,还与用于将支架定位在内腔内的隔膜相关联,并且防止进一步的轴向 当支架放置在其中时,支架相对于内腔的运动。
    • 6. 发明授权
    • Process for stent compression
    • 支架压缩方法
    • US5944735A
    • 1999-08-31
    • US961287
    • 1997-10-30
    • Nicholas A. GreenFred E. Williams, Jr.
    • Nicholas A. GreenFred E. Williams, Jr.
    • A61F2/06A61F2/84A61M29/00
    • A61F2/958A61F2002/9522
    • In accordance with the present invention, a fluid compression instrument and method for particular use in pre-surgically securing and conforming a vascular stent upon an angioplasty balloon, includes a housing for containing pressurized fluid and an elastic enclosing diaphragm secured within the housing and having an internal cavity and opening arranged to receive the stent disposed on the balloon catheter for secured compression. A pressure chamber is arranged within the housing as an envelope about the diaphragm to enable pressurized fluid forces within the pressure chamber to be imposed upon the outer surface of the diaphragm and transmitted through the diaphragm enabling circumferential application against the inserted stent in order uniformly to compress the stent with correspondingly secured purchase against the deflated balloon surface, producing complete adhesion of the stent thereon. The subsequent balloon inflation angioplasty and stent expansion is not impaired since the balloon remains in its deflated shape with the compressed stent closely conforming in contour throughout the balloon's 360.degree. periphery. The entire stent mesh is uniformly compressed down including the open stent ends which prevents the many tiny stent mesh edges from protruding out and effectively prevents both vascular abrasion as well as shifting of the stent on the deflated balloon during the angioplasty insertion procedure.
    • 根据本发明,特别用于在血管成形术球囊上手术前固定和符合血管支架的流体压缩仪器和方法包括用于容纳加压流体的壳体和固定在壳体内的弹性封闭隔膜, 内腔和开口布置成接纳设置在球囊导管上的支架,用于固定压缩。 压力室在壳体内作为围绕隔膜的信封布置,以使得压力室内的加压流体力能够施加在隔膜的外表面上,并且透过隔膜使得能够周向地施加抵靠插入的支架以均匀地压缩 所述支架相对于所述放气球囊表面具有相应的固定购买,从而在其上产生支架的完全粘附。 随后的球囊充气血管成形术和支架扩张不受损害,因为气囊保持其缩小的形状,压缩的支架在整个气球的360°周边处具有紧密的轮廓。 整个支架网均匀压缩,包括开放的支架末端,其防止许多微小的支架网边缘突出,并且在血管成形术插入过程期间有效地防止血管磨损以及支架在放气球囊上的移位。
    • 8. 发明授权
    • Liquid dispenser nozzle assembly
    • 液体分配器喷嘴总成
    • US5183184A
    • 1993-02-02
    • US664347
    • 1991-03-04
    • Joseph V. RanallettaFred E. Williams, Jr.Rowland W. Kanner
    • Joseph V. RanallettaFred E. Williams, Jr.Rowland W. Kanner
    • A61J1/14B05B11/00B05B11/04B65D47/20
    • B05B11/0021B05B11/007B05B11/047B05B11/048B65D47/2081A61J1/145A61J1/1468B01D2201/302
    • A liquid dispensing nozzle assembly is provided for mounting on a liquid container and dispenser having a flexible wall and liquid storage cavity for manually squeezed dispensing of a liquid from the cavity through the nozzle assembly. The nozzle assembly maintains the liquid, such as contact lens saline solution, in sterile condition during storage and repeated dispensing of the liquid from the container cavity. The nozzle assembly includes a liquid conduit for communication from the container cavity to a liquid discharge port from the nozzle assembly to enable dispensing of the liquid displaced by manually squeezing the flexible wall of the container. The nozzle assembly also includes an air aspiration conduit separate from the liquid conduit for aspirating air into the container cavity to replace the dispensed liquid. The nozzle assembly includes a partitioned diaphragm including separate portions respectively included in the liquid conduit and the air aspiration conduit. The air conduit portion of the diaphragm can include a filter which is hydrophobic and air permeable but impermeable to bacteria to prevent entrainment of bacteria with the aspirating flow of air into the liquid storage cavity of the container.
    • 提供液体分配喷嘴组件,用于安装在具有柔性壁和液体储存腔的液体容器和分配器上,用于通过喷嘴组件从腔体手动挤压分配液体。 喷嘴组件在储存期间将液体,例如隐形眼镜盐水溶液保持在无菌状态,并从容器腔中重复分配液体。 喷嘴组件包括用于从容器空腔与喷嘴组件连通的液体导管,用于通过手动地挤压容器的柔性壁而排出液体。 喷嘴组件还包括与液体管道分离的空气吸入管道,用于将空气吸入容器空腔以更换分配的液体。 喷嘴组件包括分隔的隔膜,其包括分别包括在液体导管和空气抽吸导管中的分离部分。 隔膜的空气导管部分可以包括疏水性和透气性但对细菌不可渗透的过滤器,以防止吸入空气进入容器的液体储存腔中的细菌夹带。
    • 9. 发明授权
    • Coagulation timer
    • 凝血定时器
    • US5572997A
    • 1996-11-12
    • US259517
    • 1994-06-14
    • Rowland W. KannerFred E. Williams, Jr.
    • Rowland W. KannerFred E. Williams, Jr.
    • A61B5/145A61B10/00A61F13/38A61B5/00
    • A61B5/02042A61B10/00A61F13/38Y10S128/22
    • A coagulation timer device is used to monitor the bleeding time of a patient to determine the amount of time required to achieve clotting. The coagulation timer device includes a carrier member, a linearly oriented absorbing medium which is affixed to the carrier member and a bag member which overlays the carrier member and the medium. The medium, such as filter paper or the like, is used to blot blood from an incision which has been formed through the skin. The medium is affixed to the carrier member and includes a plurality of segments each of which are defined by a scalloped edge portion which extends beyond the edges of the carrier member. The segments are used one at a time at predetermined intervals to blot the blood by touching the scalloped edge to the blood. Indicia is provided on the carrier member to let a medical person or technician know where the medium should be touched to the blood at each predetermined interval and provides a quick reference guide to let the technician know the amount of time that it has taken for the blood to clot. The bag member is affixed to the carrier member and is retractable to uncover the medium, while being replaceable to cover the medium.
    • 凝血定时器装置用于监测患者的出血时间以确定实现凝血所需的时间量。 凝固定时装置包括承载构件,固定在承载构件上的直线吸收介质和覆盖载体构件和介质的袋构件。 介质如滤纸等用于从通过皮肤形成的切口上吸印血液。 介质固定在承载构件上,并且包括多个段,每个段由扇形边缘部分限定,该扇形边缘部分延伸超过载体构件的边缘。 这些片段以预定间隔一次一个地使用,以通过将扇形边缘触及血液来吸印血液。 在承运人成员上提供标记,以让医疗人员或技术人员以每个预定间隔知道介质应该接触血液的位置,并提供快速参考指南,让技术人员知道其为血液所采取的时间量 凝结 袋构件被固定到承载构件上并且可缩回以露出介质,同时可更换以覆盖介质。
    • 10. 发明授权
    • Vaccine applicator system
    • 疫苗敷贴系统
    • US5487726A
    • 1996-01-30
    • US260882
    • 1994-06-16
    • Richard RabenauFred E. Williams, Jr.
    • Richard RabenauFred E. Williams, Jr.
    • A61B17/20
    • A61B17/205
    • A percutaneous vaccine applicator system which includes a percutaneous vaccine applicator and a packaging assembly for housing the vaccine applicator. The percutaneous vaccine applicator includes a handle and spiked portion attached to the handle. A plurality of spikes project from the spiked portion for puncturing the skin of a patient to deliver a percutaneous vaccine. The packaging assembly includes a hollow container and a removable cover attached to the container. The hollow container defines a cavity being sized and dimensioned for receiving the vaccine applicator. The container has structures for positively receiving and retaining an applicator placed therein.
    • 一种经皮疫苗施用器系统,其包括经皮疫苗施用器和用于容纳疫苗施用器的包装组件。 经皮疫苗施用器包括手柄和附接到手柄的加标部分。 多个尖峰从加标部分突出,用于穿刺患者的皮肤以递送经皮疫苗。 包装组件包括中空容器和附接到容器的可移除盖。 中空容器限定了尺寸和尺寸用于接收疫苗施用器的空腔。 容器具有用于积极地接收和保持放置在其中的施用器的结构。