专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US5955516A Methods of making dispersible additives for polymeric materials 失效
标题翻译：制造聚合材料分散性添加剂的方法
公开(公告)号：US5955516A
公开(公告)日：1999-09-21
申请号：US810198
申请日：1997-03-03
申请人： Donald Caswell , Frank R. Jones , Stanley A. McIntosh , Gary W. Shore , G. Daniel Gasperson
发明人： Donald Caswell , Frank R. Jones , Stanley A. McIntosh , Gary W. Shore , G. Daniel Gasperson
IPC分类号： C08J3/22 , C08K9/08 , C08K9/10 , D01D1/06 , D01F1/04 , D01F1/10 , D01F6/60 , D01F8/04 , D01F8/12 , D06N7/00 , C08K9/00
CPC分类号： B29C47/0877 , B29C47/0014 , C08J3/226 , C08K9/08 , C08K9/10 , D01D1/065 , D01F1/04 , D01F1/10 , D01F6/60 , D01F8/04 , D01F8/12 , D06N7/0065 , C08J2467/00 , C08J2477/00 , Y10T428/23993 , Y10T428/29 , Y10T428/2927
摘要： Additives for polymeric compositions are prepared by coating pigment with a dispersant, and thereafter dispersing the dispersant-coated pigment in a liquid nonaqeous polymeric carrier. Preferably, the dispersant-coated pigment is spray-dried. That is, most preferably, an aqueous dispersion of the pigment and dispersant is subjected to a spray-drying operation so as to obtain pigment coated with the dispersant. The dispersant-coated pigment will have an average particle size of about 5 .mu.m or greater, but is capable of breaking apart to average particle sizes of about 1 .mu.m or less when dispersed in a polymeric host material.
摘要翻译：通过用分散剂涂覆颜料，然后将分散剂涂覆的颜料分散在液体非聚合物载体中来制备聚合物组合物的添加剂。优选地，分散剂涂覆的颜料被喷雾干燥。也就是说，最优选地，将颜料和分散剂的水分散体进行喷雾干燥操作，以获得涂覆有分散剂的颜料。分散剂涂覆的颜料的平均粒度为约5μm或更大，但当分散在聚合物主体材料中时能够分裂成约1μm或更小的平均粒度。

2. 发明申请

US20180187211A1 METHODS AND COMPOSITIONS FOR COMBINATION IMMUNOTHERAPY 审中-公开
公开(公告)号：US20180187211A1
公开(公告)日：2018-07-05
申请号：US15542005
申请日：2016-01-07
申请人： Frank R. JONES , Elizabeth GABITZSCH , Yvette LATCHMAN , Adrian RICE , Etubics Corporation
发明人： Frank R. Jones , Elizabeth Gabitzsch , Yvette Latchman , Adrian Rice
IPC分类号： C12N15/86 , A61K39/00 , A61P35/00 , A61P35/04 , C12N7/00 , C07K14/705 , C07K14/47 , A61K45/06 , A61K39/395 , A61P31/20
CPC分类号： C12N15/86 , A61K39/0011 , A61K39/12 , A61K39/235 , A61K39/39541 , A61K39/39558 , A61K45/06 , A61K2039/505 , A61K2039/5256 , A61K2039/5258 , A61K2039/53 , A61K2039/54 , A61K2039/545 , A61K2039/575 , A61K2039/585 , A61K2039/70 , A61P31/20 , A61P35/00 , A61P35/04 , C07K14/4705 , C07K14/70596 , C07K16/2818 , C07K2317/76 , C12N7/00 , C12N2710/10023 , C12N2710/10043 , C12N2710/10071 , C12N2710/10343 , C12N2710/10371 , C12N2710/20034 , A61K2300/00
摘要： Methods for generating immune responses using adenovirus vectors that allow multiple vaccinations with the same adenovirus vector and vaccinations in individuals with preexisting immunity to adenovirus are provided.

3. 发明申请

US20130224144A1 SEQUENTIAL ADMINISTRATION OF A REPLICATION DEFECTIVE ADENOVIRUS VECTOR IN VACCINATION PROTOCOLS 审中-公开
标题翻译：疫苗接种方案中的复发性腺病毒载体的顺序施用
公开(公告)号：US20130224144A1
公开(公告)日：2013-08-29
申请号：US13622263
申请日：2012-09-18
申请人： Joseph P. Balint , Frank R. Jones , Richard B. Gayle, III
发明人： Joseph P. Balint , Frank R. Jones , Richard B. Gayle, III
IPC分类号： A61K39/235 , A61K38/20 , A61K38/21 , A61K38/19
CPC分类号： A61K39/12 , A61K38/191 , A61K38/193 , A61K38/2013 , A61K38/2026 , A61K38/2033 , A61K38/204 , A61K38/2046 , A61K38/2066 , A61K38/208 , A61K38/217 , A61K39/00 , A61K39/0011 , A61K39/21 , A61K39/235 , A61K2039/5256 , A61K2039/54 , A61K2039/545 , A61K2039/55555 , A61K2039/57 , A61K2039/575 , A61P35/00 , C07K14/005 , C07K14/70503 , C07K14/71 , C12N15/86 , C12N2710/10034 , C12N2710/10321 , C12N2710/10334 , C12N2710/10343 , C12N2710/10371 , C12N2710/20034 , C12N2740/15034 , C12N2740/16234 , C12N2800/24
摘要： Methods for generating immune responses using adenovirus vectors that allow multiple vaccinations with the same adenovirus vector and vaccinations in individuals with preexisting immunity to adenovirus are provided.
摘要翻译：提供了使用允许使用相同腺病毒载体进行多次疫苗接种的腺病毒载体产生免疫反应的方法，并且在具有预先存在的腺病毒免疫的个体中接种疫苗。

4. 发明授权

US06416859B1 Methods of making pigmented filaments 有权
标题翻译：着色长丝的制备方法
公开(公告)号：US06416859B1
公开(公告)日：2002-07-09
申请号：US09690137
申请日：2000-10-17
申请人： Donald Caswell , Frank R. Jones , David B. Ledford , Stanley A. McIntosh , Gary W. Shore , Karl H. Buchanan , Wayne S. Stanko , G. Daniel Gasperson , Charles F. Helms, Jr.
发明人： Donald Caswell , Frank R. Jones , David B. Ledford , Stanley A. McIntosh , Gary W. Shore , Karl H. Buchanan , Wayne S. Stanko , G. Daniel Gasperson , Charles F. Helms, Jr.
IPC分类号： D02G302
CPC分类号： D06N7/006 , B29C47/0009 , B29C47/0877 , C08J3/226 , C08J2467/00 , C08J2477/00 , C08K9/08 , C08K9/10 , D01D1/065 , D01F1/04 , D01F1/10 , D01F6/60 , D01F8/04 , D01F8/12 , Y10T428/2913 , Y10T428/2915
摘要： Polymeric compositions include a nonaqueous additive system having dispersant-coated pigments physically dispersed in a liquid nonaqueous polymeric carrier which may be added directly to a melt flow of a polymeric host material. The additive system employed in the polymeric systems is most preferably in the form of a particulate paste which can be added in metered amounts (dosed) to a melt flow of the polymeric host material prior to being spun into filaments. By providing a number of additive systems having a number of different additive attributes, and controllably dosing one or more into the melt flow of host polymeric material, shaped objects of the polymeric material (e.g., melt-spun filaments) having different additive attributes may be produced on a continuous basis without shutting down the shaping operation.
摘要翻译：聚合物组合物包括具有物理分散在液体非水性聚合物载体中的分散剂涂覆的颜料的非水性添加剂体系，其可以直接加入到聚合物主体材料的熔体流中。在聚合体系中使用的添加剂体系最优选为颗粒状的形式，其可以在纺丝成长丝之前以计量的量（配制）加入到聚合物主体材料的熔体流中。通过提供许多具有多种不同添加剂属性的添加剂体系，并且可控地将一种或多种配料加入主体聚合物材料的熔体流中，具有不同添加剂属性的聚合材料（例如，熔纺丝）的成型物体可以是连续生产而不关闭整形操作。

5. 发明授权

US06232371B1 Dispersible additive systems for polymeric materials, and methods of making and incorporating the same in such polymeric materials 失效
标题翻译：用于聚合物材料的可分散添加剂体系，以及在这种聚合物材料中制造和并入其的方法
公开(公告)号：US06232371B1
公开(公告)日：2001-05-15
申请号：US09075169
申请日：1998-05-11
申请人： Donald Caswell , Frank R. Jones , David B. Ledford , Stanley A. McIntosh , Gary W. Shore , Karl H. Buchanan , Wayne S. Stanko , G. Daniel Gasperson , Charles F. Helms, Jr.
发明人： Donald Caswell , Frank R. Jones , David B. Ledford , Stanley A. McIntosh , Gary W. Shore , Karl H. Buchanan , Wayne S. Stanko , G. Daniel Gasperson , Charles F. Helms, Jr.
IPC分类号： C08K900
CPC分类号： D06N7/006 , B29C47/0009 , B29C47/0877 , C08J3/226 , C08J2467/00 , C08J2477/00 , C08K9/08 , C08K9/10 , D01D1/065 , D01F1/04 , D01F1/10 , D01F6/60 , D01F8/04 , D01F8/12 , Y10T428/2913 , Y10T428/2915
摘要： Polymeric compositions include a nonaqueous additive system having dispersant-coated pigments physically dispersed in a liquid nonaqueous polymeric carrier which may be added directly to a melt flow of a polymeric host material. The additive system employed in the polymeric systems is most preferably in the form of a particulate paste which can be added in metered amounts (dosed) to a melt flow of the polymeric host material prior to being spun into filaments. By providing a number of additive systems having a number of different additive attributes, and controllably dosing one or more into the melt flow of host polymeric material, shaped objects of the polymeric material (e.g., melt-spun filaments) having different additive attributes may be produced on a continuous basis without shutting down the shaping operation.
摘要翻译：聚合物组合物包括具有物理分散在液体非水性聚合物载体中的分散剂涂覆的颜料的非水性添加剂体系，其可以直接加入到聚合物主体材料的熔体流中。在聚合体系中使用的添加剂体系最优选为颗粒状的形式，其可以在纺丝成长丝之前以计量的量（配制）加入到聚合物主体材料的熔体流中。通过提供许多具有多种不同添加剂属性的添加剂体系，并且可控地将一种或多种配料加入主体聚合物材料的熔体流中，具有不同添加剂属性的聚合材料（例如，熔纺丝）的成型物体可以是连续生产而不关闭整形操作。

6. 发明授权

US5973032A Dispersible additive systems for polymeric materials 失效
标题翻译：聚合材料的分散性添加剂体系
公开(公告)号：US5973032A
公开(公告)日：1999-10-26
申请号：US949711
申请日：1997-10-14
申请人： Donald Caswell , Frank R. Jones , Stanley A. McIntosh , Gary W. Shore , G. Daniel Gasperson
发明人： Donald Caswell , Frank R. Jones , Stanley A. McIntosh , Gary W. Shore , G. Daniel Gasperson
IPC分类号： C08J3/22 , C08K9/08 , C08K9/10 , D01D1/06 , D01F1/04 , D01F1/10 , D01F6/60 , D01F8/04 , D01F8/12 , D06N7/00 , C08J3/205 , C08K9/04
CPC分类号： B29C47/0877 , B29C47/0014 , C08J3/226 , C08K9/08 , C08K9/10 , D01D1/065 , D01F1/04 , D01F1/10 , D01F6/60 , D01F8/04 , D01F8/12 , D06N7/0065 , C08J2467/00 , C08J2477/00 , Y10T428/23993 , Y10T428/29 , Y10T428/2927
摘要： Dispersible additive systems for polymeric materials include dispersant-coated pigments in a liquid nonaqueous polymeric carrier. The additive systems are most preferably in the form of a particulate nonaqueous paste which can be added in metered amounts (dosed) to a melt flow of the polymeric host material prior to being shaped (for example, prior to being spun into synthetic filaments). By providing a number of additive systems having a number of different additive attributes, and controllably dosing one or more into the melt flow of polymeric material, shaped objects of the polymeric material (e.g., melt-spun filaments) having different additive attributes may be produced on a continuous basis without shutting down the shaping operation.
摘要翻译：用于聚合材料的可分散添加剂体系包括在液体非水性聚合物载体中的分散剂涂覆的颜料。添加剂体系最优选为颗粒状非水性浆料的形式，其可以在成形之前（例如，在纺成合成纤丝之前）以计量（定量）加入到聚合物主体材料的熔体流中。通过提供许多具有多种不同添加剂属性的添加剂体系，并且可控制地将一种或多种配料加入到聚合物材料的熔体流中，可以生产具有不同添加剂属性的聚合材料（例如，熔纺丝）的成型物不断关闭整形操作。

7. 发明授权

US5889089A Additive-containing polymeric compositions and methods of making the same 失效
标题翻译：含添加剂的聚合物组合物及其制备方法
公开(公告)号：US5889089A
公开(公告)日：1999-03-30
申请号：US810196
申请日：1997-03-03
申请人： Donald Caswell , Frank R. Jones , Stanley A. McIntosh , Gary A. Shore , G. Daniel Gasperson
发明人： Donald Caswell , Frank R. Jones , Stanley A. McIntosh , Gary A. Shore , G. Daniel Gasperson
IPC分类号： C08J3/22 , C08K9/08 , C08K9/10 , D01D1/06 , D01F1/04 , D01F1/10 , D01F6/60 , D01F8/04 , D01F8/12 , D06N7/00 , C08K9/00
CPC分类号： B29C47/0877 , B29C47/0014 , C08J3/226 , C08K9/08 , C08K9/10 , D01D1/065 , D01F1/04 , D01F1/10 , D01F6/60 , D01F8/04 , D01F8/12 , D06N7/0065 , C08J2467/00 , C08J2477/00 , Y10T428/23993 , Y10T428/29 , Y10T428/2927
摘要： Polymeric compositions include a nonaqueous additive system having dispersant-coated pigments physically dispersed in a liquid nonaqueous polymeric carrier which may be added directly to a melt flow of a polymeric host material. The additive system employed in the polymeric systsms is most preferably in the form of a particulate paste which can be added in metered amounts (dosed) to a melt flow of the polymeric host material prior to being spun into filaments. By providing a number of additive systems having a number of different additive attributes, and controllably dosing one or more into the melt flow of host polymeric material, shaped objects of the polymeric material (e.g., melt-spun filaments) having different additive attributes may be produced on a continuous basis without shutting down the shaping operation.
摘要翻译：聚合物组合物包括具有物理分散在液体非水性聚合物载体中的分散剂涂覆的颜料的非水性添加剂体系，其可以直接加入到聚合物主体材料的熔体流中。在聚合体系中使用的添加剂体系最优选为颗粒状的形式，其可以在纺丝成长丝之前以计量的量（定量）加入到聚合物主体材料的熔体流中。通过提供许多具有多种不同添加剂属性的添加剂体系，并且可控地将一种或多种配料加入主体聚合物材料的熔体流中，具有不同添加剂属性的聚合材料（例如，熔纺丝）的成型物体可以是连续生产而不关闭整形操作。

8. 发明授权

US5122112A Antigen-specific removal of circulating immune complexes 失效
标题翻译：抗原特异性去除循环免疫复合物
公开(公告)号：US5122112A
公开(公告)日：1992-06-16
申请号：US579217
申请日：1990-09-05
申请人： Frank R. Jones
发明人： Frank R. Jones
IPC分类号： G01N33/564
CPC分类号： G01N33/564 , Y10S436/828
摘要： Extracorporeal perfusion using an immunoadsorbent material specific for disease-related antigens is used for therapy of the disease state. Antibodies to particular antigens, including tumor antigens, viral antigens, and bacterial antigens, are used to prepare the immunoadsorbent material. Patients suffering from the disease are then treated by removing a flow of blood, separating the blood into plasma cellular components, passing the plasma through the immunoadsorbent material, recombining the treated plasma and cellular components of the blood, and returning the treated blood to the patient.
摘要翻译：使用特异于疾病相关抗原的免疫吸附材料的体外灌注用于治疗疾病状态。使用针对特定抗原（包括肿瘤抗原，病毒抗原和细菌抗原）的抗体来制备免疫吸附材料。然后通过去除血液流，将血液分离成等离子体细胞组分，使血浆通过免疫吸附材料，使经处理的血浆和细胞组分重新组合，并将经处理的血液返回给患者来治疗患有疾病的患者。

9. 发明申请

US20160076053A1 REPLICATION DEFECTIVE ADENOVIRUS VECTOR IN VACCINATION 有权
标题翻译：在接种中复制有缺陷的腺病毒载体
公开(公告)号：US20160076053A1
公开(公告)日：2016-03-17
申请号：US14422504
申请日：2013-03-15
申请人： Frank R. Jones , Elizabeth Gabitzsch
发明人： Frank R. Jones , Elizabeth Gabitzsch
IPC分类号： C12N15/86 , A61K39/00 , C07K14/705 , C12N7/00
CPC分类号： C12N15/86 , A61K39/0011 , A61K2039/5254 , A61K2039/5256 , A61K2039/53 , A61K2039/545 , C07K14/4748 , C07K14/70503 , C07K14/70596 , C12N7/00 , C12N2710/10034 , C12N2710/10043 , C12N2710/10343 , C12N2799/022
摘要： Methods for generating immune responses using adenovirus vectors that allow multiple vaccinations with the same adenovirus vector and vaccinations in individuals with preexisting immunity to adenovirus are provided.
摘要翻译：提供了使用允许使用相同腺病毒载体进行多次疫苗接种的腺病毒载体产生免疫反应的方法，并且在具有预先存在的腺病毒免疫的个体中接种疫苗。

10. 发明申请

US20100183673A1 METHODS AND COMPOSITIONS FOR PRODUCING AN ADENOVIRUS VECTOR FOR USE WITH MULTIPLE VACCINATIONS 有权
标题翻译：用于生产用于多种疫苗的腺病毒载体的方法和组合物
公开(公告)号：US20100183673A1
公开(公告)日：2010-07-22
申请号：US12651836
申请日：2010-01-04
申请人： Joseph P. Balint , Frank R. Jones , Richard B. Gayle, III
发明人： Joseph P. Balint , Frank R. Jones , Richard B. Gayle, III
IPC分类号： A61K39/235 , C12N15/861
CPC分类号： A61K39/12 , A61K38/191 , A61K38/193 , A61K38/2013 , A61K38/2026 , A61K38/2033 , A61K38/204 , A61K38/2046 , A61K38/2066 , A61K38/208 , A61K38/217 , A61K39/00 , A61K39/0011 , A61K39/21 , A61K39/235 , A61K2039/5256 , A61K2039/54 , A61K2039/545 , A61K2039/55555 , A61K2039/57 , A61K2039/575 , C07K14/005 , C07K14/70503 , C07K14/71 , C12N15/86 , C12N2710/10034 , C12N2710/10321 , C12N2710/10334 , C12N2710/10343 , C12N2710/10371 , C12N2710/20034 , C12N2740/15034 , C12N2740/16234 , C12N2800/24
摘要： Methods for generating immune responses using adenovirus vectors that allow multiple vaccinations with the same adenovirus vector and vaccinations in individuals with preexisting immunity to adenovirus are provided.
摘要翻译：提供了使用允许使用相同腺病毒载体进行多次疫苗接种的腺病毒载体产生免疫反应的方法，并且在具有预先存在的腺病毒免疫的个体中接种疫苗。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式