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1. 发明授权

US08500757B2 Surgical puncture cinch and closure system 有权
标题翻译：手术穿刺系带和闭合系统
公开(公告)号：US08500757B2
公开(公告)日：2013-08-06
申请号：US12844139
申请日：2010-07-27
申请人： Manouchehr Miraki , Yoon H. Kwon , Frank Nguyen
发明人： Manouchehr Miraki , Yoon H. Kwon , Frank Nguyen
IPC分类号： A61B17/04
CPC分类号： A61B17/06109 , A61B17/0482 , A61B17/0483 , A61B17/06119 , A61B2017/00243 , A61B2017/003 , A61B2017/0406 , A61B2017/06052 , A61B2017/06076 , A61B2017/06095 , A61B2090/036 , A61F2/2409
摘要： A system for forming a purse string suture, including a suture applicator having a proximal handle, a length of suture wound on a spool, and a hollow suture needle extending from a distal end of the handle. The suture needle projects distally from the handle in a helical shape and terminates in a sharp distal tip with an opening in one side close to the distal tip. A free end of the length of suture may extend out of the distal tip and back into the hollow suture needle through the opening. The suture needle may have a deflection segment adjacent the distal tip that is more flexible than the rest of the helical distal portion of the suture needle. A linear hollow pivot shaft extends from a distal end of the handle substantially along an axis of the helical distal portion of the suture needle.
摘要翻译：一种用于形成钱包线缝合的系统，包括具有近端手柄的缝合线施加器，缠绕在线轴上的一段缝线以及从手柄的远端延伸的中空缝合针。缝合针从手柄向远端突出呈螺旋状，并终止于尖锐的远端，其一侧的开口靠近远端。缝合长度的自由端可以延伸出远侧末端并通过开口返回到中空缝合针中。缝合针可以具有与远侧末端相邻的偏转部分，其比缝合针的螺旋形远端部分的其余部分更柔性。线性中空枢转轴基本上沿着缝合针的螺旋形远端部分的轴线从手柄的远端延伸。

2. 发明申请

US20100256619A1 Methods and Devices for Transpedicular Discectomy 审中-公开
标题翻译：经椎弓根切除术的方法和装置
公开(公告)号：US20100256619A1
公开(公告)日：2010-10-07
申请号：US12728013
申请日：2010-03-19
申请人： George P. Teitelbaum , Samuel M. Shaolian , Thanh Van Nguyen , Frank Nguyen , To V. Pham
发明人： George P. Teitelbaum , Samuel M. Shaolian , Thanh Van Nguyen , Frank Nguyen , To V. Pham
IPC分类号： A61B18/20
CPC分类号： A61F2/4455 , A61B17/1617 , A61B17/1642 , A61B17/1671 , A61B17/1757 , A61B17/70 , A61B18/1477 , A61B18/24 , A61B2017/003 , A61B2018/0044 , A61B2018/1425 , A61B2018/2211 , A61B2018/2238 , A61F2/30744 , A61F2/442 , A61F2/446 , A61F2/4611 , A61F2002/30092 , A61F2002/30579 , A61F2002/30599 , A61F2002/30841 , A61F2002/449 , A61F2002/4627 , A61F2210/0014 , A61F2250/0063
摘要： An embodiment of the present invention is directed to methods and devices for treating diseases and conditions that change the special relationship between vertebral bodies and intervertebral disks. A method for performing a transpedicular discectomy procedure may include creating a transpedicular channel to a first vertebral body through a first pedicle of a first vertebra; inserting a flexible drill through the transpedicular channel causing the flexible drill to make an approximately 90 degree angle, the flexible drill creating a channel through the first vertebral body into an intervertebral disk; and removing a portion of the intervertebral disk with a laser device. A laser catheter device for use in ablation and removal of intervertebral disk material in a percutaneous transpedicular approach may include an elongated tube comprising a first lumen and a second lumen, the first lumen comprising a fiber optics bundle and the second lumen for evacuation of ablated material; and a Holmium-YAG infrared laser or a laser diode for generating laser energy to the distal end through the elongated tube.
摘要翻译：本发明的一个实施例涉及用于治疗改变椎体和椎间盘之间的特殊关系的疾病和病症的方法和装置。用于执行经椎弓根椎间盘切除术的方法可包括通过第一椎骨的第一椎弓根产生经椎弓根通道到第一椎体; 将柔性钻头插入经椎弓根通道中，使得柔性钻头形成大约90度的角度，柔性钻头通过第一椎体产生通道进入椎间盘; 以及用激光装置去除椎间盘的一部分。用于在经皮经椎弓根进路中消融和去除椎间盘材料的激光导管装置可以包括细长管，其包括第一腔和第二腔，所述第一腔包括光纤束，所述第二腔用于排除消融材料 ; 以及用于通过细长管向远端产生激光能量的钬-YAG红外激光器或激光二极管。

3. 发明授权

US07318826B2 Transpedicular intervertebral disk access methods and devices 有权
标题翻译：椎弓根椎间盘入路方法及装置
公开(公告)号：US07318826B2
公开(公告)日：2008-01-15
申请号：US10420422
申请日：2003-04-22
申请人： George P. Teitelbaum , Samuel M. Shaolian , Thanh Van Nguyen , Frank Nguyen , To V. Pham , Vincent Divino, Jr. , Michael R. Henson
发明人： George P. Teitelbaum , Samuel M. Shaolian , Thanh Van Nguyen , Frank Nguyen , To V. Pham , Vincent Divino, Jr. , Michael R. Henson
IPC分类号： A61B17/56
CPC分类号： A61B17/1617 , A61B17/1642 , A61B17/1675 , A61B17/1757 , A61B17/320016 , A61B17/7097 , A61B2017/00261 , A61B2017/00867 , A61B2017/564 , A61F2/442 , A61F2002/444
摘要： A flexible drill and method of drilling a material are disclosed. According to one embodiment, a flexible drill includes a lower sub-assembly connected to an upper sub-assembly, where the lower sub-assembly comprises a retainer tube and the upper sub-assembly comprises a guiding tube; a drilling tip, and capable of orienting the drilling tip at a predetermined position after accessing a material to he drilled through a substantially straight passage having a lone axis. The predetermined position is at least 10° off of the lone axis of the substantially straight passage. According to one embodiment, a method of drilling a material includes the steps of (a) providing a flexible drill; (b) advancing the drill through a substantially straight passage until the drilling tip accesses the material to be drilled, thereby orienting the drilling tip at the predetermined position; and (c) actuating the drill.
摘要翻译：公开了一种钻孔材料的柔性钻孔和钻孔方法。根据一个实施例，柔性钻头包括连接到上部子组件的下部子组件，其中下部子组件包括保持器管，并且上部子组件包括导向管; 钻头，并且能够在将钻头从访问通过具有单独轴线的基本上直的通道钻出的材料之后定位在预定位置。预定位置距离基本上直的通道的单独轴线至少10°。根据一个实施例，钻探材料的方法包括以下步骤：（a）提供柔性钻头; （b）将钻头推进通过基本上直的通道，直到钻头接触待钻探的材料，从而将钻头定位在预定位置; 和（c）致动钻头。

4. 发明申请

US20050195991A1 Method and system for reducing pop noise of a sound broadcasting instrument 有权
标题翻译：用于减少声音广播乐器的流行噪音的方法和系统
公开(公告)号：US20050195991A1
公开(公告)日：2005-09-08
申请号：US10862917
申请日：2004-06-07
申请人： Yuhe Wang , Peter White , Daniel Ho , Frank Nguyen , Chin-Chi Chang , Jeetin Rathore
发明人： Yuhe Wang , Peter White , Daniel Ho , Frank Nguyen , Chin-Chi Chang , Jeetin Rathore
IPC分类号： H02B1/00 , H04B15/00
CPC分类号： H03F1/305 , H03F3/187 , H03G3/002 , H03M1/0881 , H03M1/66
摘要： A method and system are disclosed for controlling pop noises in a sound broadcasting system. After controllably connecting an output of a drive amplifier to a first predetermined low voltage level through a first switch, a first portion of an operation control data set is input to a digital-to-analog converter (DAC) circuit for driving an output thereof to a second predetermined low voltage level, and a second portion of the operation control data set is also input to the DAC circuit and further to the drive amplifier to bring the output of the drive amplifier to a common mode voltage level over a predetermined rise-up time period for controlling the pop noises.
摘要翻译：公开了一种用于控制声音广播系统中的弹奏噪声的方法和系统。在通过第一开关可控地将驱动放大器的输出连接到第一预定低电压电平之后，操作控制数据组的第一部分被输入到数模转换器（DAC）电路，用于驱动其输出到第二预定低电压电平和第二部分操作控制数据组也被输入到DAC电路，并进一步输入到驱动放大器，以使驱动放大器的输出达到预定上升沿的共模电压电平控制流行音色的时间段。

5. 发明授权

US5823955A Atrioventricular valve tissue ablation catheter and method 失效
标题翻译：房室瓣膜组织消融导管及方法
公开(公告)号：US5823955A
公开(公告)日：1998-10-20
申请号：US559672
申请日：1995-11-20
申请人： Karl Heinz Kuck , Frank Nguyen
发明人： Karl Heinz Kuck , Frank Nguyen
IPC分类号： A61B18/14 , A61N1/05 , A61N1/40 , A61B5/04 , A61N1/36
CPC分类号： A61B18/1492 , A61N1/056 , A61N1/403 , A61B2018/00369 , A61B2018/00654 , A61B2018/00797 , A61B2018/00821 , A61B2018/00839 , A61B2018/00952
摘要： An atrioventricular valve tissue ablation catheter (2), especially suited for treating Mahaim fibers, includes a shaft (4) with a deflectable tip (20) at the distal end (6) and a handle (10) at the proximal end (8). The tip includes a distal segment (66) curving in one direction and a proximal segment (44) curving in the opposite direction so the distal segment causes the distal segment can engage tissue on either side of the annulus (92) of the tricuspid (or mitral) valve (90). Ablation energy can be supplied through the ablation electrodes (46, 70) simultaneously or one at a time to ablate tissue at the annulus without the need for moving the catheter. Mapping electrodes (38) are provided proximal of the ablation electrodes.
摘要翻译：特别适用于治疗马赫姆纤维的房室瓣膜组织消融导管（2）包括在远端（6）处具有可偏转尖端（20）的轴（4）和近端（8）处的手柄（10）。尖端包括在一个方向上弯曲的远端段（66）和沿相反方向弯曲的近端段（44），使得远端区段使得远侧段可以接合三尖瓣环（92）的任一侧上的组织（或二尖瓣）（90）。消融能量可以通过消融电极（46,70）同时或一次一次地供应，以消除环空中的组织，而不需要移动导管。映射电极（38）设置在消融电极的近侧。

6. 发明授权

US07241297B2 Transpedicular intervertebral disk access methods and devices 有权
标题翻译：椎弓根椎间盘入路方法及装置
公开(公告)号：US07241297B2
公开(公告)日：2007-07-10
申请号：US10607070
申请日：2003-06-25
申请人： Samuel M. Shaolian , George P. Teitelbaum , Thanh Van Nguyen , Frank Nguyen , To V. Pham , Vincent Divino, Jr. , Michael R. Henson
发明人： Samuel M. Shaolian , George P. Teitelbaum , Thanh Van Nguyen , Frank Nguyen , To V. Pham , Vincent Divino, Jr. , Michael R. Henson
IPC分类号： A61B17/56
CPC分类号： A61B17/1617 , A61B17/1642 , A61B17/1675 , A61B17/1757 , A61B17/320016 , A61B17/7097 , A61B2017/00261 , A61B2017/00867 , A61B2017/564 , A61F2/442 , A61F2002/444
摘要： Methods and devices for treating diseases and conditions that change the spacial relationship between the vertebral bodies and the intervertebral disks, or that cause instability of the vertebral column, or both, and a method and devices that allow the surgeon to access the intervertebral space to restore a more normal three-dimensional configuration of the space, with or without additionally fusing two adjacent vertebrae.
摘要翻译：用于治疗改变椎体和椎间盘之间的空间关系或导致椎体柱的不稳定性或两者的疾病和病症的方法和装置，以及允许外科医生进入椎间空间以恢复的方法和装置更加正常的三维空间配置，有或没有额外地融合两个相邻的椎骨。

7. 发明申请

US20050033292A1 Methods and devices for transpedicular discectomy 审中-公开
标题翻译：经椎弓根切除术的方法和装置
公开(公告)号：US20050033292A1
公开(公告)日：2005-02-10
申请号：US10855486
申请日：2004-05-28
申请人： George Teitelbaum , Samuel Shaolian , Thanh Nguyen , Frank Nguyen , To Pham
发明人： George Teitelbaum , Samuel Shaolian , Thanh Nguyen , Frank Nguyen , To Pham
IPC分类号： A61B20060101 , A61B17/16 , A61B17/17 , A61B17/70 , A61B18/14 , A61B18/22 , A61B18/24 , A61F2/00 , A61F2/30 , A61F2/44 , A61F2/46 , A61F5/04
CPC分类号： A61F2/4455 , A61B17/1617 , A61B17/1642 , A61B17/1671 , A61B17/1757 , A61B17/70 , A61B18/1477 , A61B18/24 , A61B2017/003 , A61B2018/0044 , A61B2018/1425 , A61B2018/2211 , A61B2018/2238 , A61F2/30744 , A61F2/442 , A61F2/446 , A61F2/4611 , A61F2002/30092 , A61F2002/30579 , A61F2002/30599 , A61F2002/30841 , A61F2002/449 , A61F2002/4627 , A61F2210/0014 , A61F2250/0063
摘要： An embodiment of the present invention is directed to methods and devices for treating diseases and conditions that change the special relationship between vertebral bodies and intervertebral disks. A method for performing a transpedicular discectomy procedure may include creating a transpedicular channel to a first vertebral body through a first pedicle of a first vertebra; inserting a flexible drill through the transpedicular channel causing the flexible drill to make an approximately 90 degree angle, the flexible drill creating a channel through the first vertebral body into an intervertebral disk; and removing a portion of the intervertebral disk with a laser device. A laser catheter device for use in ablation and removal of intervertebral disk material in a percuntaneous transpedicular approach may include an elongated tube comprising a first lumen and a second lumen, the first lumen comprising a fiber optics bundle and the second lumen for evacuation of ablated material; and a Holmium-YAG infrared laser or a laser diode for generating laser energy to the distal end through the elongated tube.
摘要翻译：本发明的一个实施例涉及用于治疗改变椎体和椎间盘之间的特殊关系的疾病和病症的方法和装置。用于执行经椎弓根椎间盘切除术的方法可包括通过第一椎骨的第一椎弓根产生经椎弓根通道到第一椎体; 将柔性钻头插入经椎弓根通道中，使得柔性钻头形成大约90度的角度，柔性钻头通过第一椎体产生通道进入椎间盘; 以及用激光装置去除椎间盘的一部分。用于在经皮经椎弓根进路中消融和去除椎间盘材料的激光导管装置可以包括包括第一腔和第二腔的细长管，所述第一腔包括光纤束，所述第二腔用于排除消融材料 ; 以及用于通过细长管向远端产生激光能量的钬-YAG红外激光器或激光二极管。

8. 发明授权

US06522933B2 Steerable catheter with a control handle having a pulley mechanism 有权
公开(公告)号：US06522933B2
公开(公告)日：2003-02-18
申请号：US09822087
申请日：2001-03-30
申请人： Frank Nguyen
发明人： Frank Nguyen
IPC分类号： A61N100
CPC分类号： A61M25/0136
摘要： A steerable catheter is provided. The catheter comprises an elongated, flexible tubular catheter body having proximal and distal ends and a lumen extending therethrough and a control handle at the proximal end of the catheter body. The control handle comprises a handle housing having a generally hollow interior and fixedly attached, either directly or indirectly to the catheter body; a piston slidably mounted in the handle housing and having proximal and distal ends; and a pulley fixedly attached, either directly or indirectly to the handle housing at a location proximal to the proximal end of the piston. A first puller wire is provided having a distal end fixedly attached in the distal end of the catheter body and a proximal end anchored to the piston. A second puller wire is provided having a distal end fixedly attached in the distal end of the catheter body. The second puller wire extends through the catheter body, into the handle, and around the pulley, and the proximal end of the second puller wire is anchored to the piston.

9. 发明申请

US20060184188A1 Transpedicular intervertebral disk access methods and devices 有权
标题翻译：椎弓根椎间盘入路方法及装置
公开(公告)号：US20060184188A1
公开(公告)日：2006-08-17
申请号：US10999216
申请日：2004-11-30
申请人： Lehmann Li , George Teitelbaum , Samuel Shaolian , Michael Sherman , Frank Nguyen , Thanh Nguyen , To Pham
发明人： Lehmann Li , George Teitelbaum , Samuel Shaolian , Michael Sherman , Frank Nguyen , Thanh Nguyen , To Pham
IPC分类号： A61B17/32
CPC分类号： A61B17/1617 , A61B17/1642 , A61B17/1671 , A61B17/1757 , A61B17/320016 , A61B17/32002 , A61B17/3421 , A61B17/70 , A61B17/7001 , A61B17/7098 , A61B2017/00261 , A61B2017/003 , A61B2017/00867 , A61B2017/0256 , A61B2017/2927 , A61B2017/32004 , A61B2017/564 , A61F2/441 , A61F2/442 , A61F2/4611 , A61F2002/30291 , A61F2002/30579 , A61F2002/4415 , A61F2002/444 , A61F2002/448 , A61F2002/449 , Y10T408/85843 , Y10T408/8595
摘要： Methods and devices for treating diseases and conditions that change the spacial relationship between the vertebral bodies and the intervertebral disks, or that cause instability of the vertebral column, or both, and a method and devices that allow the surgeon to access the intervertebral space to restore a more normal three-dimensional configuration of the space, with or without additionally fusing two adjacent vertebrae.
摘要翻译：用于治疗改变椎体和椎间盘之间的空间关系或导致椎体柱的不稳定性或两者的疾病和病症的方法和装置，以及允许外科医生进入椎间空间以恢复的方法和装置更加正常的三维空间配置，有或没有额外地融合两个相邻的椎骨。

10. 发明授权

US06551271B2 Asymmetrical bidirectional steerable catheter 有权
公开(公告)号：US06551271B2
公开(公告)日：2003-04-22
申请号：US09846732
申请日：2001-04-30
申请人： Frank Nguyen
发明人： Frank Nguyen
IPC分类号： A61M3700
CPC分类号： A61B18/1492 , A61B34/20 , A61B2017/00053 , A61B2017/003 , A61B2034/2051
摘要： A bidirectional steerable catheter is provided that can be deflected to form two different curves, i.e., two curves each having a different radius of curvature. The catheter comprises an elongated, flexible tubular catheter body having proximal and distal ends and a lumen extending therethrough. A tip section is provided at the distal end of the catheter body. The tip section comprises a flexible plastic tubing having at least first and second off-axis lumens extending therethrough. A control handle is attached to the proximal end of the catheter body. A first puller wire extends through the lumen of the catheter body and the first off-axis lumen of the tip section. The first puller wire has a distal end anchored in the tip section and a proximal end anchored to the control handle. A second puller wire extends through the lumen of the catheter body and the second off-axis lumen of the tip section. The second puller wire has a distal end anchored in the tip section and a proximal end anchored to the control handle. A first compression coil extends through the lumen of the catheter body in surrounding relation to the first puller wire. The first compression coil has a distal end anchored in the catheter body or in the first off-axis lumen of the tip section at a first anchor position. A second compression coil extends through the lumen of the catheter body in surrounding relation to the second puller wire and into the second off-axis lumen. The second compression coil has a distal end anchored in the second off-axis lumen of the tip section at a second anchor position that is distal to the first anchor position. By this design, the radius of curvature of each curve achieved by deflection of the tip section is controlled by the anchor position of the compression coil surrounding the appropriate puller wire.

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