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1. 发明申请

WO0226242A2 INHIBITION OF SYSTEMIC INFECTIONS IN HUMANS AND VERTEBRATES BY DIETARY FIBERS 审中-公开
标题翻译：膳食纤维对人体和人体系统性感染的抑制作用
公开(公告)号：WO0226242A2
公开(公告)日：2002-04-04
申请号：PCT/EP0111198
申请日：2001-09-27
申请人： UNIV MISSISSIPPI , TIENSE SUIKERRAFFINADERIJ NV , BUDDINGTON RANDAL K , LOO JAN VAN , FRIPPIAT ANNE
发明人： BUDDINGTON RANDAL K , VAN LOO JAN , FRIPPIAT ANNE
IPC分类号： A23K1/16 , A23L1/308 , A61K31/715 , A61K31/717 , A61K31/731 , A61K31/732 , A61K31/733 , A61K36/00 , A61K36/28 , A61P31/04 , A61K35/78
CPC分类号： A61K31/715 , A23L33/22 , A23V2002/00 , A23V2250/0632 , A23V2250/5062 , A23V2250/5118 , A23V2250/54246 , A23V2250/628
摘要： The use of a dietary fiber or mixture of dietary fibers for the manufacture of a composition, such as a pharmaceutical composition, a functional food or a functional feed, for the prevention, the inhibition and/or treatment of systemic infections in humans and in vertebrates caused by pathogenic bacteria is disclosed. A method for preventing and/or inhibiting the systemic growth of pathogenic bacteria in humans and vertebrates, and a method for the prevention, the inhibition and/or the treatment of systemic infections in humans and in vertebrates caused by pathogenic bacteria, comprising administration to said beings a composition containing an effective amount of a dietary fiber or mixture of dietary fibers, are also disclosed. The dietary fiber is preferably a fructan, typically inulin and/or oligofructose, most preferably chicory inulin with an average degree of polymerisation DP of at least 20. The composition and methods are useful for the prevention, inhibition and/or treatment of systemic infections in fish, particularly during cultivation in fish farms.
摘要翻译：膳食纤维或膳食纤维混合物用于制造用于预防，抑制和/或治疗人和脊椎动物全身感染的组合物如功能性食物或功能性饲料的组合物的用途由致病菌引起的泄露。一种用于预防和/或抑制人和脊椎动物中致病细菌的全身性生长的方法，以及预防，抑制和/或治疗由致病细菌引起的人类和脊椎动物中的系统感染的方法，所述方法包括向所述还公开了含有有效量膳食纤维或膳食纤维混合物的组合物。膳食纤维优选为果聚糖，通常为菊糖和/或低聚果糖，最优选为具有至少20的平均聚合度DP的菊苣菊糖。所述组合物和方法可用于预防，抑制和 /或治疗鱼类全身感染，特别是在养鱼场种植期间。

2. 发明申请

WO1994022327A1 STABILISED FOOD COMPOSITION 审中-公开
标题翻译：稳定食品组合物
公开(公告)号：WO1994022327A1
公开(公告)日：1994-10-13
申请号：PCT/BE1994000025
申请日：1994-03-28
申请人： RAFFINERIE TIRLEMONTOISE S.A. , FRIPPIAT, Anne
发明人： RAFFINERIE TIRLEMONTOISE S.A.
IPC分类号： A23L01/052
CPC分类号： A23C19/054 , A23D7/015 , A23L13/65 , A23L27/60 , A23L29/244
摘要： A stabilised food composition with a reduced dry matter content, wherein the stabilising agent is a fructane or fructane mixture in an amount of 1-15 wt % and to 1-25 % of the water content of said food composition.
摘要翻译：一种具有减少的干物质含量的稳定的食物组合物，其中所述稳定剂是所述食物组合物的含水量为1-15重量％和1-25重量％的果聚糖或果聚糖混合物。

3. 发明申请

WO2005036990A1 COMPOSITION FOR PREVENTION, INHIBITION AND TREATMENT OF OBESITY AND RELATED DISEASES 审中-公开
标题翻译：用于预防，抑制和治疗肥胖及相关疾病的组合物
公开(公告)号：WO2005036990A1
公开(公告)日：2005-04-28
申请号：PCT/EP2004/010907
申请日：2004-09-30
申请人： TIENSE SUIKERRAFFINADERIJ N.V. , DELZENNE, Nathalie, Maria , CANI, Patrice, Daniel , FRIPPIAT, Anne
发明人： DELZENNE, Nathalie, Maria , CANI, Patrice, Daniel , FRIPPIAT, Anne
IPC分类号： A23L1/308
CPC分类号： A23L33/24 , A23L33/22 , A23L33/30
摘要： The use is provided of a combination of a fermentable dietary fibre and a food product for the manufacture of a composition for oral administration or tube feeding for the prevention, the inhibition of the development, and the treatment of obesity and obesity-related diseases in humans and mammals. The composition inhibits the synthesis and/or release and the effects of the appetite-stimulating hormone ghrelin, and provokes a suppression of plasma ghrelin levels that in the post-absorptive period 8 hours after intake is preferably at least 30 % lower than the plasma ghrelin concentration of controls having taken only said food product. Also a method is provided for the prevention, the inhibition of the development, and the treatment of overweight, obesity and obesity-related diseases in humans and mammals. A method is provided too for suppressing plasma ghrelin levels, for inhibiting the synthesis and/or release and the effects of the appetite-stimulating hormone ghrelin, in humans and mammals. The methods involve oral intake or administration through tube feeding of a composition comprising said combination of fermentable dietary fibre and food product.
摘要翻译：提供了可发酵膳食纤维和食品的组合的用途，用于制造用于口服或管饲的组合物，用于预防，抑制发育，以及治疗人体中的肥胖和肥胖相关疾病和哺乳动物。该组合物抑制食欲刺激激素生长素释放肽的合成和/或释放和作用，并且引起血浆生长素释放肽水平的抑制，其在摄入后8小时的吸收后期间优选比血浆生长素释放肽低至少30％对照品的浓度仅服用所述食品。还提供了用于预防，抑制发育以及治疗人和哺乳动物中的超重，肥胖和肥胖相关疾病的方法。还提供了一种抑制血浆生长素释放肽水平的方法，用于抑制人和哺乳动物中促进激素的生长素释放肽的合成和/或释放及其作用。所述方法涉及口服摄入或通过管饲喂包含所述可发酵膳食纤维和食品的组合的组合物。

4. 发明申请

WO1993006744A1 COMPOSITIONS HAVING A CREAMY STRUCTURE AND CONTAINING FRUCTANE, PREPARATION METHOD THEREFOR AND USES THEREOF 审中-公开
标题翻译：具有乳化结构和含有FRUCTANE的组合物，其制备方法及其用途
公开(公告)号：WO1993006744A1
公开(公告)日：1993-04-15
申请号：PCT/BE1992000042
申请日：1992-10-02
申请人： RAFFINERIE TIRLEMONTOISE S.A. , FRIPPIAT, Anne , SMITS, Georges
发明人： RAFFINERIE TIRLEMONTOISE S.A.
IPC分类号： A23L01/0528
CPC分类号： A23G1/46 , A23G1/325 , A23G1/40 , A23G1/48 , A23G3/46 , A23L27/60 , A23L29/231 , A23L29/244 , A23L29/25 , A23L33/21
摘要： Compositions having a creamy structure and containing a fructane or fructanes mixed with a liquid such as water, milk, egg white, egg yolk or sugar syrup; and the use of said compositions in foodstuffs such as ice cream, salad dressings, chocolate preparations, meat products, breads and pastries, fillings, sandwich spreads, jam, dairy products, sauces, etc., are described. Foodstuffs containing such compositions are also described.
摘要翻译：具有奶油结构并含有与液体如水，牛奶，蛋清，蛋黄或糖浆混合的果聚糖或果聚糖的组合物; 并且描述了在食品中使用所述组合物，例如冰淇淋，沙拉酱，巧克力制剂，肉制品，面包和糕点，馅料，三明治酱，果酱，乳制品，调味汁等。还描述了含有这种组合物的食品。

5. 发明申请

WO2004028527A1 SYNERGISTIC COMBINATIONS OF DIETARY FIBER AND N-SAIDS FOR THE TREATMENT OF CANCER 审中-公开
标题翻译：用于治疗癌症的膳食纤维和N-糖苷的协同组合
公开(公告)号：WO2004028527A1
公开(公告)日：2004-04-08
申请号：PCT/EP2003/010544
申请日：2003-09-23
申请人： TIENSE SUIKERRAFFINADERIJ N.V. , VAN LOO, Jan , FRIPPIAT, Anne , HERMANS, Johny
发明人： VAN LOO, Jan , FRIPPIAT, Anne , HERMANS, Johny
IPC分类号： A61K31/19
CPC分类号： A61K31/19 , A61K31/715
摘要： Pharmaceutical compositions are disclosed that present synergistic anti-cancer effects in humans and vertebrate animals, comprising a combination of a fermentable dietary fiber (FDF) which is a fructan and a non-steroidal anti-inflammatory drug (NSAID) with cyclo-oxygenase2 (COX2) inhibiting activity, the FDF being present in the FDF/NSAID combination in a weight ratio FDF: NSAID of minimum 1:1. Typical compositions comprise a FDF/NSAID combination wherein the FDF component is chicory inulin, oligofructose or a mixture thereof, and the NSAID component is sulindac, piroxicam or aspirin. The synergistic ant-cancer effects of the compositions are demonstrated in aberrant crypt foci studies in rats. The pharmaceutical compositions are useful in the prevention and inhibition of carcinogenesis or recurrence of cancer and for the treatment of cancer in humans and vertebrate animals. The invention also relates to a method for prevention or inhibition of carcinogenesis and recurrence of cancer and for the treatment of cancer in humans and vertebrate animals involving administration of a therapeutically effective dose of said pharmaceutical compositions to a human or vertebrate animal.
摘要翻译：公开了药物组合物，其在人和脊椎动物中表现出协同的抗癌作用，其包括作为果聚糖的可发酵膳食纤维（FDF）和非甾体抗炎药（NSAID）与环氧合酶2（COX2）的组合）抑制活性，FDF存在于FDF / NSAID组合中，重量比FDF：NSAID最小为1：1。典型的组合物包含FDF / NSAID组合，其中FDF组分是菊苣菊糖，低聚果糖或其混合物，NSAID组分是舒林酸，吡罗昔康或阿司匹林。在大鼠的异常隐窝灶研究中证明了组合物的协同抗癌作用。药物组合物可用于预防和抑制癌症的癌发生或复发以及用于治疗人类和脊椎动物的癌症。本发明还涉及用于预防或抑制癌症的癌发生和复发以及用于治疗人类和脊椎动物中的癌症的方法，其涉及向人或脊椎动物施用治疗有效剂量的所述药物组合物。

6. 发明申请

WO1993006737A1 HYDRATED LIPOPHILIC COMPOSITION AND METHOD FOR OBTAINING SAME 审中-公开
标题翻译：水解液体组合物及其制备方法
公开(公告)号：WO1993006737A1
公开(公告)日：1993-04-15
申请号：PCT/BE1992000043
申请日：1992-10-02
申请人： RAFFINERIE TIRLEMONTOISE (S.A) , FRIPPIAT, Anne , DE SOETE, Johan , SMITS, Georges , KEME, Thomas
发明人： RAFFINERIE TIRLEMONTOISE (S.A)
IPC分类号： A23G01/00
CPC分类号： A23G1/46 , A23G1/325 , A23G1/40 , A23G1/48 , A23G3/46 , A23L27/60 , A23L29/231 , A23L29/244 , A23L29/25 , A23L33/21
摘要： A hydrated lipophilic composition comprising a lipophilic component with an aqueous component in which the water is immobilized. A method for preparing the hydrated lipophilic composition is also provided.
摘要翻译：一种水合亲油性组合物，其包含亲水性组分与其中水被固定的水性组分。还提供了一种制备水合亲脂性组合物的方法。

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