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1. 发明申请

WO2010033778A3 MEDICAL INJECTOR WITH DOSE KNOB ACTIVATION FOR AUTOMATED RECONSTITUTION 审中-公开
公开(公告)号：WO2010033778A3
公开(公告)日：2010-03-25
申请号：PCT/US2009/057439
申请日：2009-09-18
申请人： BECTON, DICKINSON AND COMPANY , FAYYAZ, Asif , CRONENBERG, Richard, A. , VEDRINE, Lionel
发明人： FAYYAZ, Asif , CRONENBERG, Richard, A. , VEDRINE, Lionel
IPC分类号： A61M5/20 , A61M5/178 , A61M5/14
摘要： A medical injector is provided herein having a body and a reservoir disposed in the body, the reservoir including at icast first and second rrπxable components. At least one stopper is associated with the reservoir where dista! advancement of the stopper over a predetermined distance causes mixing of the mixable components. A plunger is disposed in the body, along with a knob stem and a knob fixed to the knob stem so as to be rotatabie therewith. A sleeve is telescopingly disposed over the knob stem, wherein the knob stem and the sleeve have cooperating elements formed thereon which selectively permit rotation of the knob stem to be transmitted to the sleeve so that the knob stem and the sleeve may rotate together. A spring is also provided for urging the sleeve distally. A releasabie retainer releasably retains the sleeve against force of the spring. Rotation of the knob releases the sleeve and allows the spring to displace the sleeve distally. Distal movement of the sleeve causes distal movement of the plunger which causes distal movement of the stopper thus causing mixing of the mixable components. Advantageously, with the subject invention, a medical injector may be provided where autoreconstitution can be achieved by the turning of a knob.

2. 发明申请

WO2010033790A3 MEDICAL INJECTOR WITH ROTATABLE BODY PORTIONS 审中-公开
标题翻译：医疗注射器与可旋转的身体部位
公开(公告)号：WO2010033790A3
公开(公告)日：2010-06-17
申请号：PCT/US2009057460
申请日：2009-09-18
申请人： BECTON DICKINSON CO , CRONENBERG RICHARD A , FAYYAZ ASIF , PATEL ATUL , VEDRINE LIONEL
发明人： CRONENBERG RICHARD A , FAYYAZ ASIF , PATEL ATUL , VEDRINE LIONEL
IPC分类号： A61M5/20 , A61M5/315
CPC分类号： A61M5/2033 , A61M5/2448 , A61M5/3129 , A61M5/31553 , A61M5/3156 , A61M2005/2073
摘要： A medical injector is provided herein which includes first and second body portions rotatabiy coupled together; a displaceable plunger disposed in at least one of the first and second body portions: a spring disposed to advance the plunger; and, a releasable retainer for retaining the plunger in a first portion against force of the spring. The releasable retainer releases the plunger upon a predetermined extent of relative rotation between the first and second body portions, thus allowing the spring to advance the plunger. Advantageously, the subject invention provides a medical injector having an automated plunger drive which is triggered upon rotation of injector body portions, thereby minimizing premature or failed activations.
摘要翻译：本文提供了一种医疗注射器，其包括可旋转地联接在一起的第一和第二主体部分; 设置在所述第一和第二主体部分中的至少一个中的可移动柱塞：设置成使所述柱塞前进的弹簧; 以及用于抵抗弹簧的力而将柱塞保持在第一部分中的可释放保持器。可释放的保持器在第一和第二主体部分之间的预定的相对旋转程度上释放柱塞，从而允许弹簧推进柱塞。有利地，本发明提供一种具有自动柱塞驱动器的医用注射器，其在喷射器主体部分的旋转时被触发，由此最小化过早或失败的激活。

3. 发明申请

WO2010033808A2 MEDICAL INJECTOR WITH POST-AUTORECONSTITUTION DOSE SETTING AND AUTOPLUNGER DRIVE 审中-公开
标题翻译：医疗注射器后自动注射剂量设置和自动驾驶仪驱动器
公开(公告)号：WO2010033808A2
公开(公告)日：2010-03-25
申请号：PCT/US2009/057485
申请日：2009-09-18
申请人： BECTON, DICKINSON AND COMPANY , CRONENBERG, Richard, A. , FAYYAZ, Asif , PATEL, Atul , VEDRINE, Lionel
发明人： CRONENBERG, Richard, A. , FAYYAZ, Asif , PATEL, Atul , VEDRINE, Lionel
IPC分类号： A61M5/20 , A61M5/315
CPC分类号： A61M5/19 , A61M5/2033 , A61M5/2066 , A61M5/2448 , A61M5/3129 , A61M5/31553 , A61M5/3156
摘要： A medical injector is provided herein having a body; a reservoir containing first and second mixable components, a stopper associated with the reservoir, a predetermined extent of advancement of the stopper causing mixing of the first and second mixable components; a displaceable plunger disposed in the body; a spring disposed to advance the plunger; a first releasable retainer for releasably retaining the plunger in a first state against force of the spring; a first trigger for causing the first releasable retainer to release the plunger; a second releasable retainer for releasably retaining the plunger in a second state against force of the spring; and, a second trigger for causing the second releasable retainer to release the plunger. The spring causes the plunger to advance from the first state to the second state. The plunger engages the stopper during the advancement from the first state to the second state so that the stopper traverses at least the predetermined extent of advancement thereby causing mixing of the first and second mixable components. Advantageously, with the subject invention, a medical injector is provided which allows for auto reconstitution with subsequent dose setting and auto plunger activation, the auto reconstitution and the auto plunger activations being activated by separate triggers.
摘要翻译：本文提供了一种医用注射器，其具有主体; 包含第一和第二可混合组分的贮存器，与贮存器相关联的塞子，塞子的预定程度推进导致第一和第二可混合组分的混合; 设置在主体中的可移动柱塞; 设置成推进柱塞的弹簧; 第一可释放保持器，用于克服弹簧的力可释放地将柱塞保持在第一状态; 用于使所述第一可释放保持器释放所述柱塞的第一触发器; 第二可释放保持器，用于克服弹簧的力可释放地将柱塞保持在第二状态; 以及用于使第二可释放保持器释放柱塞的第二触发器。弹簧使柱塞从第一状态进入第二状态。柱塞在从第一状态前进到第二状态期间接合止动件，使得止动件至少穿过预定的前进程度，从而引起第一和第二可混合部件的混合。有利地，对于本发明，提供了一种医用注射器，其允许随后的剂量设定和自动柱塞激活自动重构，自动重构和自动柱塞激活由单独的触发器激活。

4. 发明申请

WO2010033806A3 NEEDLE MOUNTING FEATURE FOR ENSURING PROPER RECONSTITUTION SEQUENCE 审中-公开
标题翻译：用于确保正确重组序列的针安装特征
公开(公告)号：WO2010033806A3
公开(公告)日：2010-07-01
申请号：PCT/US2009057483
申请日：2009-09-18
申请人： BECTON DICKINSON CO , CRONENBERG RICHARD A , FAYYAZ ASIF , PATEL ATUL , SWEENEY MATTHEW DYLAN , VEDRINE LIONEL
发明人： CRONENBERG RICHARD A , FAYYAZ ASIF , PATEL ATUL , SWEENEY MATTHEW DYLAN , VEDRINE LIONEL
IPC分类号： A61M5/178 , A61M5/24 , A61M5/32
CPC分类号： A61M5/2448 , A61M5/2066 , A61M5/3129 , A61M5/3134 , A61M5/3243 , A61M5/344 , A61M5/347 , A61M2005/2407 , A61M2005/2496 , A61M2005/3104
摘要： A medical injector is provided herein having a body and a needle mounting surface movable relative to the body, the needle mounting surface having features for mounting a needle thereto. In an initial state, the needle mounting surface is disposed within the body with no need!e mounted thereto. With relative movement between the body and the needle mounting surface, the needle mounting surface is urged out of the body. Advantageously, a medical injector is provided which ensures proper sequence in preparation of the device, particularly with respect to the step of allowing mounting of a medical needle to the device subsequent to preparation of the medicament to be administered.
摘要翻译：本文提供了一种医用注射器，其具有主体和相对于主体可移动的针安装表面，针安装表面具有用于将针安装到其上的特征。在初始状态下，针安装表面设置在主体内而不需要安装到其中。随着主体和针头安装表面之间的相对运动，针头安装表面被推出体外。有利的是，提供一种医用注射器，其确保装置制备中的正确顺序，特别是关于在准备待施用的药物之后允许将医用针安装到装置的步骤。

5. 发明申请

WO2010033806A2 NEEDLE MOUNTING FEATURE FOR ENSURING PROPER RECONSTITUTION SEQUENCE 审中-公开
标题翻译：用于确保适当重新配置顺序的针脚安装功能
公开(公告)号：WO2010033806A2
公开(公告)日：2010-03-25
申请号：PCT/US2009/057483
申请日：2009-09-18
申请人： BECTON, DICKINSON AND COMPANY , CRONENBERG, Richard, A. , FAYYAZ, Asif , PATEL, Atul , SWEENEY, Matthew, Dylan , VEDRINE, Lionel
发明人： CRONENBERG, Richard, A. , FAYYAZ, Asif , PATEL, Atul , SWEENEY, Matthew, Dylan , VEDRINE, Lionel
IPC分类号： A61M5/178 , A61M5/32 , A61M5/24
CPC分类号： A61M5/2448 , A61M5/2066 , A61M5/3129 , A61M5/3134 , A61M5/3243 , A61M5/344 , A61M5/347 , A61M2005/2407 , A61M2005/2496 , A61M2005/3104
摘要： A medical injector is provided herein having a body and a needle mounting surface movable relative to the body, the needle mounting surface having features for mounting a needle thereto. In an initial state, the needle mounting surface is disposed within the body with no need!e mounted thereto. With relative movement between the body and the needle mounting surface, the needle mounting surface is urged out of the body. Advantageously, a medical injector is provided which ensures proper sequence in preparation of the device, particularly with respect to the step of allowing mounting of a medical needle to the device subsequent to preparation of the medicament to be administered.
摘要翻译：本发明提供了一种具有可相对于身体移动的主体和针安装表面的医疗注射器，针安装表面具有用于将针安装到其上的特征。在初始状态下，针安装表面设置在主体内，无需安装在其上。通过主体和针安装表面之间的相对移动，针安装表面被推出身体。有利地，提供了一种医疗注射器，其确保在制备装置时的适当顺序，特别是关于在制备要施用的药物之后允许将医用针安装到装置的步骤。

6. 发明申请

WO2010033808A3 MEDICAL INJECTOR WITH POST-AUTORECONSTITUTION DOSE SETTING AND AUTOPLUNGER DRIVE 审中-公开
标题翻译：医用注射器具有自动跟踪剂量设定和自动启动器驱动
公开(公告)号：WO2010033808A3
公开(公告)日：2010-07-01
申请号：PCT/US2009057485
申请日：2009-09-18
申请人： BECTON DICKINSON CO , CRONENBERG RICHARD A , FAYYAZ ASIF , PATEL ATUL , VEDRINE LIONEL
发明人： CRONENBERG RICHARD A , FAYYAZ ASIF , PATEL ATUL , VEDRINE LIONEL
IPC分类号： A61M5/20 , A61M5/315
CPC分类号： A61M5/19 , A61M5/2033 , A61M5/2066 , A61M5/2448 , A61M5/3129 , A61M5/31553 , A61M5/3156
摘要： A medical injector is provided herein having a body; a reservoir containing first and second mixable components, a stopper associated with the reservoir, a predetermined extent of advancement of the stopper causing mixing of the first and second mixable components; a displaceable plunger disposed in the body; a spring disposed to advance the plunger; a first releasable retainer for releasably retaining the plunger in a first state against force of the spring; a first trigger for causing the first releasable retainer to release the plunger; a second releasable retainer for releasably retaining the plunger in a second state against force of the spring; and, a second trigger for causing the second releasable retainer to release the plunger. The spring causes the plunger to advance from the first state to the second state. The plunger engages the stopper during the advancement from the first state to the second state so that the stopper traverses at least the predetermined extent of advancement thereby causing mixing of the first and second mixable components. Advantageously, with the subject invention, a medical injector is provided which allows for auto reconstitution with subsequent dose setting and auto plunger activation, the auto reconstitution and the auto plunger activations being activated by separate triggers.
摘要翻译：本发明提供一种具有身体的医用注射器; 容纳第一和第二可混合部件的储存器，与储存器相关联的止动件，塞子的预定范围的前进，引起第一和第二可混合部件的混合; 设置在本体中的可移位柱塞; 设置成使柱塞前进的弹簧; 第一可释放保持器，用于将柱塞可释放地保持在第一状态，抵抗弹簧的力; 用于使第一可释放保持器释放柱塞的第一触发器; 第二可释放保持器，用于将所述柱塞可释放地保持在抵抗所述弹簧的力的第二状态; 以及用于使第二可释放保持器释放柱塞的第二触发器。弹簧使柱塞从第一状态前进到第二状态。在从第一状态进入第二状态期间，柱塞接合止动件，使得止动件至少穿过预定的前进范围，从而引起第一和第二可混合部件的混合。有利地，利用本发明，提供了一种医疗注射器，其允许随后的剂量设定和自动柱塞活化自动重建，自动重建和自动柱塞激活由单独的触发器激活。

7. 发明申请

WO2010033790A2 MEDICAL INJECTOR WITH ROTATABLE BODY PORTIONS 审中-公开
标题翻译：带可旋转身体部位的医用注射器
公开(公告)号：WO2010033790A2
公开(公告)日：2010-03-25
申请号：PCT/US2009/057460
申请日：2009-09-18
申请人： BECTON, DICKINSON AND COMPANY , CRONENBERG, Richard, A. , FAYYAZ, Asif , PATEL, Atul , VEDRINE, Lionel
发明人： CRONENBERG, Richard, A. , FAYYAZ, Asif , PATEL, Atul , VEDRINE, Lionel
IPC分类号： A61M5/20 , A61M5/315
CPC分类号： A61M5/2033 , A61M5/2448 , A61M5/3129 , A61M5/31553 , A61M5/3156 , A61M2005/2073
摘要： A medical injector is provided herein which includes first and second body portions rotatabiy coupled together; a displaceable plunger disposed in at least one of the first and second body portions: a spring disposed to advance the plunger; and, a releasable retainer for retaining the plunger in a first portion against force of the spring. The releasable retainer releases the plunger upon a predetermined extent of relative rotation between the first and second body portions, thus allowing the spring to advance the plunger. Advantageously, the subject invention provides a medical injector having an automated plunger drive which is triggered upon rotation of injector body portions, thereby minimizing premature or failed activations.
摘要翻译：本文提供了一种医用注射器，其包括可旋转地联接在一起的第一和第二本体部分; 设置在第一和第二主体部分中的至少一个中的可移动柱塞;设置成推进柱塞的弹簧; 以及用于克服弹簧的力将柱塞保持在第一部分中的可释放保持器。可释放保持器在第一和第二主体部分之间的预定程度的相对旋转时释放柱塞，从而允许弹簧推进柱塞。有利地，本发明提供了一种具有自动柱塞驱动器的医用注射器，其在注射器本体部分旋转时被触发，从而最小化过早或失败的激活。

8. 发明申请

WO2010033778A2 MEDICAL INJECTOR WITH DOSE KNOB ACTIVATION FOR AUTOMATED RECONSTITUTION 审中-公开
标题翻译：医用注射器，用于自动重建的药物激活
公开(公告)号：WO2010033778A2
公开(公告)日：2010-03-25
申请号：PCT/US2009057439
申请日：2009-09-18
申请人： BECTON DICKINSON CO , FAYYAZ ASIF , CRONENBERG RICHARD A , VEDRINE LIONEL
发明人： FAYYAZ ASIF , CRONENBERG RICHARD A , VEDRINE LIONEL
IPC分类号： A61M5/20 , A61M5/14 , A61M5/178
CPC分类号： A61M5/2066 , A61M5/2448 , A61M5/3146 , A61M5/31553 , A61M5/3156 , A61M5/3158 , A61M5/31591
摘要： A medical injector is provided herein having a body and a reservoir disposed in the body, the reservoir including at icast first and second rrpxable components. At least one stopper is associated with the reservoir where dista! advancement of the stopper over a predetermined distance causes mixing of the mixable components. A plunger is disposed in the body, along with a knob stem and a knob fixed to the knob stem so as to be rotatabie therewith. A sleeve is telescopingly disposed over the knob stem, wherein the knob stem and the sleeve have cooperating elements formed thereon which selectively permit rotation of the knob stem to be transmitted to the sleeve so that the knob stem and the sleeve may rotate together. A spring is also provided for urging the sleeve distally. A releasabie retainer releasably retains the sleeve against force of the spring. Rotation of the knob releases the sleeve and allows the spring to displace the sleeve distally. Distal movement of the sleeve causes distal movement of the plunger which causes distal movement of the stopper thus causing mixing of the mixable components. Advantageously, with the subject invention, a medical injector may be provided where autoreconstitution can be achieved by the turning of a knob.
摘要翻译：本发明提供了一种医疗注射器，其具有设置在身体中的主体和储存器，所述储存器包括在第一和第二可拆卸部件处。至少有一个塞子与储存器相关联，其中dista！塞子超过预定距离使得可混合部件的混合。柱塞被设置在主体中，以及旋钮杆和固定到旋钮杆上的旋钮，以便与其旋转。套筒可伸缩地设置在旋钮杆上，其中旋钮杆和套筒具有形成在其上的协作元件，其选择性地允许旋钮杆旋转以传递到套筒，使得旋钮杆和套筒可以一起旋转。还提供用于向远侧推动套筒的弹簧。可释放的保持器可释放地保持套筒抵抗弹簧的力。旋钮的旋转释放套筒并允许弹簧向远侧移动套筒。套筒的远端运动引起柱塞的远端运动，导致塞子的远端运动，从而引起可混合部件的混合。有利地，对于本发明，可以提供医疗注射器，其中可以通过旋转旋钮来实现自动重构。

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