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1. 发明申请

WO03026556A3 BREATH-ENHANCED ULTRASONIC NEBULIZER AND DEDICATED UNIT DOSE AMPOULE 审中-公开
标题翻译：增强超声波净化器和专用单位剂量
公开(公告)号：WO03026556A3
公开(公告)日：2003-10-09
申请号：PCT/US0227712
申请日：2002-08-30
申请人： IVAX CORP , IVAX U K LTD , BARNEY BRIAN , CHEW SOPHIA , FAIRBURN PAUL , O'LEARY DAVID , STRIEBIG RACHEL
发明人： BARNEY BRIAN , CHEW SOPHIA , FAIRBURN PAUL , O'LEARY DAVID , STRIEBIG RACHEL
IPC分类号： A61M11/00 , A61M15/00 , A61M16/20 , B05B17/06 , A61M16/00 , B05B1/08
CPC分类号： A61M15/0028 , A61M15/0016 , A61M15/0018 , A61M15/0033 , A61M15/0085 , A61M16/208 , A61M2205/14
摘要： A medicament delivery system (10) comprises a nebulizer device (11), an open-faced mist chamber-defining element (12) having a tubular input/output port (31), a tubular inhalation port (15) connecting to the output port (31) of the mist chamber-defining element (12), and a sealed unit dose ampoule (14) adapted to fit within the mist chamber-defining element (12). The nebulizer device (11) includes an ultrasonic transducer (21) responsive to applied electrical energy to generate ultrasonic energy, an ultrasonic transmission horn (23) between an input energy surface (25) at an input end and an energy delivery surface (27) at an output end. The sealed unit dose ampoule (14) can be placed directly into the nebulizer device (11) and acts as both the dose cup and baffle, so that the chance of spillage of drug and the number of components to be cleaned are minimized. The unit dose ampoule (14) has a conical base (28) to allow ultrasonic energy conducted from the ultrasonic system to be concentrated at the base of the ampoule (14). The inhalation port (15) includes an inhalation valve (62) and an exhalation valve (64).
摘要翻译：药物输送系统（10）包括喷雾器装置（11），具有管状输入/输出端口（31）的开放式雾室确定元件（12），连接到输出端口的管状吸入口（15）（13），以及适于装配在雾室限定元件（12）内的密封单元剂量安瓿（14）。喷雾器装置（11）包括响应所施加的电能以产生超声波能量的超声换能器（21），在输入端的输入能量表面（25）和能量输送表面（27）之间的超声波传播喇叭（23）在输出端。密封单位剂量安瓿瓶（14）可以直接放置在喷雾器装置（11）中，同时作为剂量杯和挡板两者，使药物溢出的可能性和要清洗的部件数量最小化。单位剂量安瓿（14）具有锥形基部（28），以允许从超声波系统传导的超声能量集中在安瓿（14）的底部。吸入口（15）包括吸入阀（62）和呼气阀（64）。

2. 发明申请

WO2003026556A2 BREATH-ENHANCED ULTRASONIC NEBULIZER AND DEDICATED UNIT DOSE AMPOULE 审中-公开
标题翻译：增强超声波净化器和专用单位剂量
公开(公告)号：WO2003026556A2
公开(公告)日：2003-04-03
申请号：PCT/US2002/027712
申请日：2002-08-30
申请人： IVAX CORPORATION , IVAX U.K., LTD. , BARNEY, Brian , CHEW, Sophia , FAIRBURN, Paul , O'LEARY, David , STRIEBIG, Rachel , STRIEBIG, Rachel
发明人： BARNEY, Brian , CHEW, Sophia , FAIRBURN, Paul , O'LEARY, David , STRIEBIG, Rachel , STRIEBIG, Rachel
IPC分类号： A61J
CPC分类号： A61M15/0028 , A61M15/0016 , A61M15/0018 , A61M15/0033 , A61M15/0085 , A61M16/208 , A61M2205/14
摘要： A medicament delivery system comprises a nebulizer device, an open-faced mist chamber-defining element having a tubular input/output port, a tubular inhalation port connecting to the output port of the mist chamber-defining element, and a sealed unit dose ampoule adapted to fit within the mist chamber-defining element. The nebulizer device includes an ultrasonic transducer responsive to applied electrical energy to generate ultrasonic energy, an ultrasonic transmission horn between an input energy surface at an input end and an energy delivery surface at an output end. The sealed unit dose ampoule can be placed directly into the nebulizer device and acts as both the dose cup and baffle, so that the chance of spillage of drug and the number of components to be cleaned are minimized. The unit dose ampoule has a conical base to allow ultrasonic energy conducted from the ultrasonic system to be concentrated at the base of the ampoule. The inhalation port includes an inhalation valve and an exhalation valve.
摘要翻译：药物输送系统包括雾化器装置，具有管状输入/输出端口的开放式雾室限定元件，连接到雾室限定元件的输出端口的管状吸入口，以及适于以配合在雾室限定元件内。喷雾器装置包括响应于所施加的电能以产生超声能量的超声换能器，在输入端的输入能量表面与输出端的能量输送表面之间的超声波传播喇叭。密封单位剂量安瓿可以直接放置在雾化器装置中并充当剂量杯和挡板，使得药物溢出的可能性和待清洁的组分数量最小化。单位剂量安瓿具有锥形基底，以允许从超声系统传导的超声能量集中在安瓿的底部。吸入口包括吸入阀和呼气阀。

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