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1. 发明申请

US20080030736A1 Optical Sources for SPR Applications 有权
标题翻译：光源用于SPR应用
公开(公告)号：US20080030736A1
公开(公告)日：2008-02-07
申请号：US11462681
申请日：2006-08-04
申请人： Evan P. Thrush , Gregory D. VanWiggeren , Douglas M. Baney
发明人： Evan P. Thrush , Gregory D. VanWiggeren , Douglas M. Baney
IPC分类号： G01N21/41
CPC分类号： G01N21/553
摘要： The use of a high power and an incoherent light source to reduce noise associated when investigating unknown molecules in Surface Plasmon Resonance (SPR) systems. High power and incoherent light sources can improve resolution and accuracy of SPR system measurements.
摘要翻译：使用高功率和非相干光源来减少在研究表面等离子体共振（SPR）系统中未知分子时相关的噪声。大功率和非相干光源可以提高SPR系统测量的分辨率和精度。

2. 发明授权

US08306607B1 Implantable sensing arrangement and approach 失效
标题翻译：植入式感应装置和方法
公开(公告)号：US08306607B1
公开(公告)日：2012-11-06
申请号：US10979091
申请日：2004-11-01
申请人： Ofer Levi , Evan P. Thrush , James S. Harris , Stepehn J. Smith , Krishna V. Shenoy
发明人： Ofer Levi , Evan P. Thrush , James S. Harris , Stepehn J. Smith , Krishna V. Shenoy
IPC分类号： A61B5/00
CPC分类号： A61B5/0086 , A61B5/0031 , A61B5/0071 , A61B5/4064 , A61B2562/046
摘要： Characteristics of biological substances, such as cerebral cortex matter, are sensed. According to an example embodiment, the present invention is directed to a negligibly-intrusive, multi-layer integrated circuit arrangement for monitoring activity of an area of a cerebral cortex that would normally be covered by an anatomical layer. The multi-layer integrated circuit arrangement includes an optics layer located outside the cerebral cortex area that includes an emitter and a detector. The optics layer is adapted for implantation in the anatomical layer and for sensing at least one brain-activity parameter. The multi-layered integrated circuit arrangement also includes a data-processing layer that includes a digital-processing circuit that is adapted for assimilating neural data in response to the optics layer sensing at least one brain-activity parameter.
摘要翻译：感觉到生物物质如大脑皮层物质的特征。根据示例性实施例，本发明涉及一种用于监测通常被解剖层覆盖的大脑皮质区域的活动的可忽略不计的多层集成电路装置。多层集成电路装置包括位于大脑皮质区域外部的光学层，该光学层包括发射器和检测器。光学层适于植入解剖层并用于感测至少一个脑活动参数。多层集成电路装置还包括数据处理层，其包括数字处理电路，该数字处理电路适于响应于感测至少一个脑活动参数的光学层而吸收神经数据。

3. 发明授权

US07705990B2 Optical sources for SPR applications 有权
标题翻译： SPR应用的光源
公开(公告)号：US07705990B2
公开(公告)日：2010-04-27
申请号：US11462681
申请日：2006-08-04
申请人： Evan P. Thrush , Gregory D. VanWiggeren , Douglas M Baney
发明人： Evan P. Thrush , Gregory D. VanWiggeren , Douglas M Baney
IPC分类号： G01N21/55
CPC分类号： G01N21/553
摘要： The use of a high power and an incoherent light source to reduce noise associated when investigating unknown molecules in Surface Plasmon Resonance (SPR) systems. High power and incoherent light sources can improve resolution and accuracy of SPR system measurements.
摘要翻译：使用高功率和非相干光源来减少在研究表面等离子体共振（SPR）系统中未知分子时相关的噪声。大功率和非相干光源可以提高SPR系统测量的分辨率和精度。

4. 发明授权

US07604981B1 Excitable target marker detection 失效
标题翻译：可兴奋的靶标检测
公开(公告)号：US07604981B1
公开(公告)日：2009-10-20
申请号：US10384166
申请日：2003-03-07
申请人： James S. Harris, Jr. , Stephen J. Smith , Evan P. Thrush , Ofer Levi
发明人： James S. Harris, Jr. , Stephen J. Smith , Evan P. Thrush , Ofer Levi
IPC分类号： C12M1/34 , C12M3/00 , G01N21/64 , G01N33/53 , G01N21/00
CPC分类号： G01N21/6454 , G01N21/6408
摘要： A variety of types of molecules are detected and/or analyzed using an integrated micro-circuit arrangement. According to an example embodiment of the present invention, a micro-circuit arrangement detects excitable target markers in response to an excitation source. The excitation source emits a first electromagnetic radiation to excite one or more target markers into emitting a second electromagnetic radiation. The excitation source and detector combination can be optimized to detect a specific characteristic of a biological specimen. In this manner, an excitation source can be combined with several optical-detectors or detection channels, where each optical-detector is measuring or sensing the same or different characteristic of the biological specimen.
摘要翻译：使用集成微电路装置检测和/或分析各种类型的分子。根据本发明的示例性实施例，微电路装置响应于激发源检测可激发的目标标记。激发源发射第一电磁辐射以激发一个或多个目标标记物发射第二电磁辐射。可以优化激发源和检测器组合以检测生物样品的特定特征。以这种方式，激发源可以与几个光学检测器或检测通道组合，其中每个光学检测器正在测量或感测生物样本的相同或不同的特性。

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