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1. 发明申请

US20100242137A1 POLYNUCLEOTIDES ENCODING PROTEINS INVOLVED IN PLANT METABOLISM 失效
标题翻译：编码参与植物代谢的蛋白质的多核苷酸
公开(公告)号：US20100242137A1
公开(公告)日：2010-09-23
申请号：US12794916
申请日：2010-06-07
申请人： Quinn Qun Zhu , Sabine S. Hantke , Xiping Niu , Zheng Peizhong , Michele Morgante , Joan T. Odell , Saverio Carl Falco , Yiwen Fang , J. Antoni Rafalski , Hajime Sakai , Edgar B. Cahoon , Rebecca E. Cahoon , Jian-Ming Lee , Guo-Hua Miao , Zhongsen Li , Anthony J. Kinney
发明人： Quinn Qun Zhu , Sabine S. Hantke , Xiping Niu , Zheng Peizhong , Michele Morgante , Joan T. Odell , Saverio Carl Falco , Yiwen Fang , J. Antoni Rafalski , Hajime Sakai , Edgar B. Cahoon , Rebecca E. Cahoon , Jian-Ming Lee , Guo-Hua Miao , Zhongsen Li , Anthony J. Kinney
IPC分类号： A01H1/00 , C07H21/04 , C12N15/74 , C12N5/10 , A01H5/00 , A01H5/10 , C07K14/00 , C07K7/08 , C40B30/02 , G06F17/30
CPC分类号： C12N9/12 , C07K14/415 , C12N9/1205 , C12N15/8243 , C12N15/8261 , C12N15/827 , G06F19/20 , G06F19/22 , Y02A40/146
摘要： The invention provides isolated pyruvate dehydrogenase kinase nucleic acids and their encoded polypeptides. The present invention provides methods and compositions relating to altering pyruvate dehydrogenase kinase levels in plants. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions.
摘要翻译：本发明提供了分离的丙酮酸脱氢酶激酶核酸及其编码的多肽。本发明提供了关于在植物中改变丙酮酸脱氢酶激酶水平的方法和组合物。本发明还提供了重组表达盒，宿主细胞，转基因植物和抗体组合物。

2. 发明授权

US07498483B2 Phospholipid:diacylglycerol acyltransferases 失效
公开(公告)号：US07498483B2
公开(公告)日：2009-03-03
申请号：US11930384
申请日：2007-10-31
申请人： Karlene H. Butler , Rebecca E. Cahoon , Omolayo O. Famodu , Sarah E. Hall , Edgar B. Cahoon
发明人： Karlene H. Butler , Rebecca E. Cahoon , Omolayo O. Famodu , Sarah E. Hall , Edgar B. Cahoon
IPC分类号： A01H1/00 , C07H21/04 , C12N15/29 , C12N15/52 , C07K14/415
CPC分类号： C12N15/8247 , C12N9/1029 , C12Y203/0102
摘要： This invention relates to an isolated nucleic acid fragment encoding an acyltransferase, more specifically a phospholipid:diacylglycerol acyltransferase. The invention also relates to the construction of a recombinant DNA construct encoding all or a portion of the phospholipid:diacylglycerol acyltransferase, in sense or antisense orientation, wherein expression of the recombinant DNA construct results in production of altered levels of the phospholipid:diacylglycerol acyltransferase in a transformed host cell.

3. 发明授权

US5654402A Methods and compositions relating to plant .DELTA..sup.6 palmitoyl-acyl carrier protein desaturase 失效
标题翻译：与植物DELTA 6棕榈酰酰基载体蛋白质去饱和酶相关的方法和组合物
公开(公告)号：US5654402A
公开(公告)日：1997-08-05
申请号：US329560
申请日：1994-10-26
申请人： Edgar B. Cahoon , John B. Ohlrogee
发明人： Edgar B. Cahoon , John B. Ohlrogee
IPC分类号： C12N9/02 , C12N15/82 , C07K14/415 , C12N9/04 , C12N15/29
CPC分类号： C12N9/0083 , C12N15/8247
摘要： A plant .DELTA..sup.6 palmitoyl-acyl carrier protein desaturase, the gene encoding the desaturase, and transgenic plants and plant cells containing the heterologous DNA encoding the desaturase are described. The desaturase introduces a double bond at the sixth carbon atom from the carboxyl end of a 16 carbon saturated fatty acid, and is therefore useful in production of plant seeds having a modified fatty acid profile.
摘要翻译：描述了植物DELTA 6棕榈酰酰基载体蛋白去饱和酶，编码去饱和酶的基因，以及含有编码去饱和酶的异源DNA的转基因植物和植物细胞。去饱和酶在16碳饱和脂肪酸的羧基末端的第六个碳原子处引入双键，因此可用于生产具有改性脂肪酸分布的植物种子。

4. 发明申请

US20110214204A1 POLYNUCLEOTIDES ENCODING PROTEINS INVOLVED IN PLANT METABOLISM 失效
标题翻译：编码参与植物代谢的蛋白质的多核苷酸
公开(公告)号：US20110214204A1
公开(公告)日：2011-09-01
申请号：US13105949
申请日：2011-05-12
申请人： Quinn Qun Zhu , Sabine S. Hantke , Xiping Niu , Zheng Peizhong , Michele Morgante , Joan T. Odell , Saverio Carl Falco , Yiwen Fang , J. Antoni Rafalski , Hajime Sakai , Edgar B. Cahoon , Rebecca E. Cahoon , Jian-Ming Lee , Guo-Hua Miao , Zhongsen Li , Anthony J. Kinney
发明人： Quinn Qun Zhu , Sabine S. Hantke , Xiping Niu , Zheng Peizhong , Michele Morgante , Joan T. Odell , Saverio Carl Falco , Yiwen Fang , J. Antoni Rafalski , Hajime Sakai , Edgar B. Cahoon , Rebecca E. Cahoon , Jian-Ming Lee , Guo-Hua Miao , Zhongsen Li , Anthony J. Kinney
IPC分类号： A01H1/00 , C12N9/02 , C12N5/10 , C12N15/82 , C40B30/02 , C07H21/04 , A01H5/00 , A01H5/06 , G06G7/58
CPC分类号： C12N9/12 , C07K14/415 , C12N9/1205 , C12N15/8243 , C12N15/8261 , C12N15/827 , G06F19/20 , G06F19/22 , Y02A40/146
摘要： The invention provides isolated pyruvate dehydrogenase kinase nucleic acids and their encoded polypeptides. The present invention provides methods and compositions relating to altering pyruvate dehydrogenase kinase levels in plants. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions.
摘要翻译：本发明提供了分离的丙酮酸脱氢酶激酶核酸及其编码的多肽。本发明提供了关于在植物中改变丙酮酸脱氢酶激酶水平的方法和组合物。本发明还提供了重组表达盒，宿主细胞，转基因植物和抗体组合物。

5. 发明授权

US07732668B2 Floral development genes 失效
标题翻译：花卉发育基因
公开(公告)号：US07732668B2
公开(公告)日：2010-06-08
申请号：US11561462
申请日：2006-11-20
申请人： Olga Danilevskaya , Pedro Herman , Edward Bruggemann , David M Shirbroun , Evgueni Ananiev , Antoni J Rafalski , Hajime Sakai , Edgar B Cahoon , Rebecca E Cahoon , Theodore M Klein
发明人： Olga Danilevskaya , Pedro Herman , Edward Bruggemann , David M Shirbroun , Evgueni Ananiev , Antoni J Rafalski , Hajime Sakai , Edgar B Cahoon , Rebecca E Cahoon , Theodore M Klein
IPC分类号： C12N15/29 , C12N15/82 , C12N15/87 , A01H5/00
CPC分类号： C12N15/8214 , C07K14/415 , C12N15/8261 , C12N15/8287 , C12N15/8289 , Y02A40/146
摘要： This invention relates to an isolated nucleic acid fragment encoding floral development proteins, more specifically FT, TFL or Ap3 homologs. The invention also relates to the construction of a recombinant DNA construct encoding all or a portion of the floral development proteins, in sense or antisense orientation, wherein expression of the recombinant DNA construct results in production of altered levels of the FT, TFL or Ap3 homologs in a transformed host cell.
摘要翻译：本发明涉及编码花发育蛋白的分离的核酸片段，更具体地说是FT，TFL或Ap3同源物。本发明还涉及在正义或反义方向上构建编码全部或部分花发育蛋白的重组DNA构建体，其中重组DNA构建体的表达导致产生改变的FT，TFL或Ap3同源物的水平在转化的宿主细胞中。

6. 发明申请

US20090054247A1 POLYNUCLEOTIDES ENCODING PROTEINS INVOLVED IN PLANT METABOLISM 失效
标题翻译：编码参与植物代谢的蛋白质的多核苷酸
公开(公告)号：US20090054247A1
公开(公告)日：2009-02-26
申请号：US12254139
申请日：2008-10-20
申请人： Quinn Qun Zhu , Sabine S. Hantke , Xiping Niu , Zheng Peizhong , Michele Morgante , Joan T. Odell , Saverio Carl Falco , Yiwen Fang , J. Antoni Rafalski , Hajime Sakai , Edgar B. Cahoon , Rebecca E. Cahoon , Jian-Ming Lee , Guo-Hua Miao , Zhongsen Li , Anthony J. Kinney
发明人： Quinn Qun Zhu , Sabine S. Hantke , Xiping Niu , Zheng Peizhong , Michele Morgante , Joan T. Odell , Saverio Carl Falco , Yiwen Fang , J. Antoni Rafalski , Hajime Sakai , Edgar B. Cahoon , Rebecca E. Cahoon , Jian-Ming Lee , Guo-Hua Miao , Zhongsen Li , Anthony J. Kinney
IPC分类号： C40B30/02 , C07H21/00 , C12N15/63 , C12N5/04 , A01H5/00 , C07K14/415 , G06G7/48
CPC分类号： C12N9/12 , C07K14/415 , C12N9/1205 , C12N15/8243 , C12N15/8261 , C12N15/827 , G06F19/20 , G06F19/22 , Y02A40/146
摘要： The invention provides isolated pyruvate dehydrogenase kinase nucleic acids and their encoded polypeptides. The present invention provides methods and compositions relating to altering pyruvate dehydrogenase kinase levels in plants. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions.
摘要翻译：本发明提供了分离的丙酮酸脱氢酶激酶核酸及其编码的多肽。本发明提供了关于在植物中改变丙酮酸脱氢酶激酶水平的方法和组合物。本发明还提供重组表达盒，宿主细胞，转基因植物和抗体组合物。

7. 发明授权

US06686186B2 Mutant fatty acid desaturase 有权
标题翻译：突变型脂肪酸去饱和酶
公开(公告)号：US06686186B2
公开(公告)日：2004-02-03
申请号：US09988929
申请日：2001-12-03
申请人： John Shanklin , Edgar B. Cahoon
发明人： John Shanklin , Edgar B. Cahoon
IPC分类号： C12N902
CPC分类号： C12N9/0083 , C12N15/8247
摘要： The present invention relates to a method for producing mutants of a fatty acid desaturase having a substantially increased activity towards fatty acid substrates with chains containing fewer than 18 carbons relative to an unmutagenized precursor desaturase having an 18 carbon atom chain length substrate specificity. The method involves inducing one or more mutations in the nucleic acid sequence encoding the precursor desaturase, transforming the mutated sequence into an unsaturated fatty acid auxotroph cell such as MH13 E. coli, culturing the cells in the absence of supplemental unsaturated fatty acids, thereby selecting for recipient cells which have received and which express a mutant fatty acid desaturase with an elevated specificity for fatty acid substrates having chain lengths of less than 18 carbon atoms. A variety of mutants having 16 or fewer carbon atom chain length substrate specificities are produced by this method. Mutant desaturases produced by this method can be introduced via expression vectors into prokaryotic and eukaryotic cells and can also be used in the production of transgenic plants which may be used to produce specific fatty acid products.
摘要翻译：本发明涉及一种生产脂肪酸去饱和酶突变体的方法，该突变体相对于具有18个碳原子链长基底特异性的未成熟前体去饱和酶，具有对具有少于18个碳的链的脂肪酸底物具有显着增加的活性。该方法包括在编码前体去饱和酶的核酸序列中诱导一个或多个突变，将突变的序列转化为不饱和脂肪酸营养缺陷型细胞如MH13大肠杆菌，在不存在补充不饱和脂肪酸的情况下培养细胞，从而选择对于接受并且表达具有链长度小于18个碳原子的脂肪酸底物具有特异性提高的突变脂肪酸去饱和酶的受体细胞。通过该方法制备具有16个或更少碳原子链长基底特异性的各种突变体。通过该方法产生的突变型去饱和酶可以通过表达载体导入原核和真核细胞中，并且还可用于生产可用于产生特定脂肪酸产物的转基因植物。

8. 发明授权

US06242256B1 Ornithine biosynthesis enzymes 有权
标题翻译：鸟氨酸生物合成酶
公开(公告)号：US06242256B1
公开(公告)日：2001-06-05
申请号：US09347798
申请日：1999-07-02
申请人： Edgar B. Cahoon , Rebecca E. Cahoon , William D. Hitz , J. Antoni Rafalski
发明人： Edgar B. Cahoon , Rebecca E. Cahoon , William D. Hitz , J. Antoni Rafalski
IPC分类号： C12N510
CPC分类号： C12N9/0008 , C12N9/1029 , C12N9/1217 , C12N15/8251
摘要： This invention relates to an isolated nucleic acid fragment encoding an ornithine biosynthetic enzyme. The invention also relates to the construction of a chimeric gene encoding all or a portion of the ornithine biosynthetic enzyme, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the ornithine biosynthetic enzyme in a transformed host cell.
摘要翻译：本发明涉及编码鸟氨酸生物合成酶的分离的核酸片段。本发明还涉及在正义或反义方向上编码全部或部分鸟氨酸生物合成酶的嵌合基因的构建，其中嵌合基因的表达导致在转化的宿主细胞中产生改变的鸟氨酸生物合成酶水平。

9. 发明授权

US5705391A Modified acyl-ACP desaturase 失效
公开(公告)号：US5705391A
公开(公告)日：1998-01-06
申请号：US689823
申请日：1996-08-14
申请人： Edgar B. Cahoon , John Shanklin , Ylva Lindgvist , Gunter Schneider
发明人： Edgar B. Cahoon , John Shanklin , Ylva Lindgvist , Gunter Schneider
IPC分类号： C12N15/09 , C12N1/15 , C12N1/21 , C12N5/10 , C12N9/02 , C12N15/00 , C12N15/11 , C12N15/29 , C12N15/82 , C12N1/00 , C12N5/00
CPC分类号： C12N9/0083 , C12N15/8247 , C07K2319/00
摘要： Disclosed is a methods for modifying the chain length and double bond positional specificities of a soluble plant fatty acid desaturase. More specifically, the method involves modifying amino acid contact residues in the substrate binding channel of the soluble fatty acid desaturase which contact the fatty acid. Specifically disclosed is the modification of an acyl-ACP desaturase. Amino acid contact residues which lie within the substrate binding channel are identified, and subsequently replaced with different residues to effect the modification of activity.

10. 发明授权

US08269076B2 Compositions and methods for altering tocotrienol content 失效
标题翻译：用于改变生育三烯酚含量的组合物和方法
公开(公告)号：US08269076B2
公开(公告)日：2012-09-18
申请号：US12578760
申请日：2009-10-14
申请人： Edgar B. Cahoon , Sean J. Coughlan , Rebecca E. Cahoon , Karlene H. Butler
发明人： Edgar B. Cahoon , Sean J. Coughlan , Rebecca E. Cahoon , Karlene H. Butler
IPC分类号： A01H5/00 , A01H5/10 , C12N15/29 , C12N15/52 , C12N15/54 , C12N15/82
CPC分类号： C12N15/8243 , C12N15/52 , G11B5/11
摘要： The invention provides isolated nucleic acids and their encoded polypeptides that alter tocol content in seeds. The invention further provides expression cassettes, host cells and transformed plants containing the nucleic acids. The present invention further provides methods for altering tocol content in seeds.
摘要翻译：本发明提供分离的核酸及其编码的多肽，其改变种子中的多糖含量。本发明进一步提供含有核酸的表达盒，宿主细胞和转化植物。本发明进一步提供了改变种子中的多糖含量的方法。

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