专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明专利

GB611747A Improvements in or relating to x-ray contrast media 未知
公开(公告)号：GB611747A
公开(公告)日：1948-11-03
申请号：GB980046
申请日：1946-03-29
申请人： MAY & BAKER LTD , GEORGE NEWBERY , DENNIS DAVID LIBMAN
IPC分类号： C07C43/20
摘要： Ethers of the formula R being a secondary alkyl group containing not less than 4 and not more than 8 carbon atoms are prepared by known methods for the production of ethers of the aromatic series from the corresponding alcohol and especially by the Williamson synthesis. According to examples: (1) the sec-octyl ether of 2 : 4 : 6-tri-iodophenol is prepared by dissolving metallic sodium in ethyl alcohol, adding 2 : 4 : 6-tri-iodophenol, when solution is complete adding sec-octyl bromide and further ethyl alcohol, and refluxing the mixture; (2) the sec-butyl ether of 2 : 4 : 6-tri-iodophenol is prepared by the procedure of example (1) by replacing sec-octyl bromide with sec-butyl bromide.ALSO:An X-ray contrast medium for internal administration comprises an ether of the formula: R being a secondary alkyl group containing not less than 4 and not more than 8 carbon atoms. It may be employed in solution in an oil such as poppy seed oil or in the form of aqueous dispersions incorporating, if desired, suitable dispersing and/or stabilizing agents. The ethers may also be used in admixture.