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1. 发明专利

CA2464030A1 RAMP BOARD 未知
公开(公告)号：CA2464030A1
公开(公告)日：2005-10-08
申请号：CA2464030
申请日：2004-04-08
申请人： LESLIE DAVID GARRETT , GAMAY DEVELOPMENTS INC
发明人： LESLIE DAVID GARRETT
IPC分类号： A63C17/01 , A63C17/02

2. 发明申请

WO2019165232A1 INHIBITORS OF PHOSPHOLIPID SYNTHESIS AND METHODS OF USE 审中-公开
公开(公告)号：WO2019165232A1
公开(公告)日：2019-08-29
申请号：PCT/US2019/019185
申请日：2019-02-22
申请人： THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY , GOUW, Arvin , FELSHER, Dean W. , JIN, Feng , ZARE, Richard N. , MARGULIS, Katherine , SCHOW, Steven R. , GREENHOUSE, Robert , LOUGHHEAD, David Garrett , RICHARDS, Steven
发明人： GOUW, Arvin , FELSHER, Dean W. , JIN, Feng , ZARE, Richard N. , MARGULIS, Katherine , SCHOW, Steven R. , GREENHOUSE, Robert , LOUGHHEAD, David Garrett , RICHARDS, Steven
IPC分类号： A61K31/18 , A61K31/196 , C07C311/21 , A61P3/00
摘要： Inhibitors of Glycerol 3-Phosphate Acyltransferase (GPAT) are provided; and methods of use in the treatment of cancer; and treatment of conditions relating to metabolic syndrome and hyperlipidemia.

3. 发明申请

WO2005077363A1 HETEROCYCLIC GABA-A SUBTYPE SELECTIVE RECEPTOR MODULATORS 审中-公开
标题翻译：杂环GABA-A亚型选择性受体调节剂
公开(公告)号：WO2005077363A1
公开(公告)日：2005-08-25
申请号：PCT/EP2005/001406
申请日：2005-02-11
申请人： F. HOFFMANN-LA ROCHE AG , LOUGHHEAD, David, Garrett , NOVAKOVIC, Sanja , O'YANG, Counde , PUTMAN, David, George , SOTH, Michael
发明人： LOUGHHEAD, David, Garrett , NOVAKOVIC, Sanja , O'YANG, Counde , PUTMAN, David, George , SOTH, Michael
IPC分类号： A61K31/437
CPC分类号： A61K31/437 , A61K31/5383 , C07D471/04 , C07D487/04
摘要： This invention relates to the use of compounds of formula (I) for the manufacture of a medicament useful for modulating α 2 subtype GABA A receptors. The invention further relates to novel heteocyclic compounds and pharmaceutical compositions containing said compounds. In addition the invention relates to the treatment of depression, an anxiety disorder, a psychiatric disorder, a learning or cognitive disorder, a sleep disorder, a convulsive or seizure disorder or pain.
摘要翻译：本发明涉及式（I）化合物在制备可用于调节α2亚型GABA A受体的药物中的用途。本发明还涉及含有所述化合物的新颖的杂环化合物和药物组合物。此外，本发明涉及治疗抑郁症，焦虑症，精神障碍，学习或认知障碍，睡眠障碍，惊厥或癫痫发作或疼痛。

4. 发明申请

WO2009043784A1 CYCLOPROPYL ARYL AMIDE DERIVATIVES AND USES THEREOF 审中-公开
标题翻译：环丙基氨基甲酰胺衍生物及其用途
公开(公告)号：WO2009043784A1
公开(公告)日：2009-04-09
申请号：PCT/EP2008/062813
申请日：2008-09-25
申请人： F. HOFFMANN-LA ROCHE AG , DU BOIS, Daisy Joe , HURST, David Nigel , LOUGHHEAD, David Garrett , MAAG, Hans , MANKA, Jason , SMITH, David Bernard
发明人： DU BOIS, Daisy Joe , HURST, David Nigel , LOUGHHEAD, David Garrett , MAAG, Hans , MANKA, Jason , SMITH, David Bernard
IPC分类号： A61K31/16 , A61P25/28 , C07C235/42 , C07C317/14 , C07C235/62 , C07C233/65 , C07C233/66 , C07C233/67 , C07C235/54 , C07C311/38 , C07C317/32 , C07D213/82 , C07D261/18 , C07C233/74 , C07C255/60
CPC分类号： C07C235/42 , C07C233/65 , C07C233/66 , C07C233/67 , C07C233/74 , C07C235/54 , C07C235/62 , C07C255/60 , C07C311/46 , C07C317/32 , C07C2601/02 , C07D213/82 , C07D261/18
摘要： Compounds of the formula (I) wherein Ar 1 , Ar 2 , R 1 and R 2 are as defined herein. Also provided are pharmaceutical compositions, methods of using, and methods of preparing the subject compounds.
摘要翻译：其中Ar1，Ar2，R1和R2如本文所定义的式（I）化合物。还提供了药物组合物，使用方法和制备本发明化合物的方法。

5. 发明申请

WO2005016892A1 GABANERGIC MODULATORS 审中-公开
标题翻译：制动调节器
公开(公告)号：WO2005016892A1
公开(公告)日：2005-02-24
申请号：PCT/EP2004/008767
申请日：2004-08-05
申请人： F. HOFFMANN-LA ROCHE AG , LIN, Xiao-Fa , LOUGHHEAD, David, Garrett , NOVAKOVIC, Sanja , O'YANG, Counde , PUTMAN, David, George , SOTH, Michael
发明人： LIN, Xiao-Fa , LOUGHHEAD, David, Garrett , NOVAKOVIC, Sanja , O'YANG, Counde , PUTMAN, David, George , SOTH, Michael
IPC分类号： C07D231/56
CPC分类号： C07D409/04 , C07D231/56 , C07D401/04 , C07D403/06 , C07D405/04 , C07D417/04 , C07D471/04 , C07D487/04
摘要： This invention relates to the use of compounds of benzoindazole derivatives salts and solvates thereof for the preparation of a medicament for modulating alpha2 subtype GABA A receptors. The invention further relates to novel heterocyclic compounds and pharmaceutical compositions containing said compounds. In addition the invention relates to the use of compounds of formula (I) salts and solvates thereof for the preparation of a medicament for the treatment of depression, an anxiety disorder, a psychiatric disorder, a learning or cognitive disorder, a sleep disorder, a convulsive or seizure disorder or pain.
摘要翻译：本发明涉及苯并吲唑衍生物盐及其溶剂化物的化合物在制备用于调节α2亚型GABA A受体的药物中的用途。本发明还涉及含有所述化合物的新型杂环化合物和药物组合物。此外，本发明涉及式（I）化合物及其溶剂化物的用途，用于制备治疗抑郁症，焦虑症，精神障碍，学习或认知障碍，睡眠障碍，惊厥或癫痫发作或疼痛。

6. 发明申请

WO2007115966A1 HETEROCYCLIC GABA ALPHA SUBTYPE SELECTIVE RECEPTOR MODULATORS 审中-公开
标题翻译：异种GABA ALPHA亚型选择性受体调节剂
公开(公告)号：WO2007115966A1
公开(公告)日：2007-10-18
申请号：PCT/EP2007/053151
申请日：2007-04-02
申请人： F. HOFFMANN-LA ROCHE AG , LIN, Xiao-Fa , LOUGHHEAD, David Garrett , MANKA, Jason , O'YANG, Counde , SOTH, Michael , YASUDA, Dennis Mitsugu
发明人： LIN, Xiao-Fa , LOUGHHEAD, David Garrett , MANKA, Jason , O'YANG, Counde , SOTH, Michael , YASUDA, Dennis Mitsugu
IPC分类号： C07D403/06 , C07D403/04 , C07D413/04 , C07D413/06 , A61K31/416 , A61P25/22 , A61P25/24
CPC分类号： C07D403/04 , C07D403/06 , C07D413/04 , C07D413/06
摘要： The present invention provides a compound of the formula (I) or pharmaceutically acceptable salts, solvates or prodrugs thereof, wherein Y, Ar, R 1 and R 2 are defined herein. Also provided are pharmaceutical compositions, their use and methods of preparing the compounds.
摘要翻译：本发明提供式（I）化合物或其药学上可接受的盐，溶剂合物或前药，其中Y，Ar，R 1和R 2定义在本文中。还提供了药物组合物，它们的用途和制备化合物的方法。

7. 发明申请

WO0248929A8 PERSONALISED FINANCIAL PRODUCTS AND COMPUTER IMPLEMENTED MANAGEMENT SYSTEM 审中-公开
标题翻译：个人化财务产品和计算机实施管理系统
公开(公告)号：WO0248929A8
公开(公告)日：2003-01-09
申请号：PCT/GB0105092
申请日：2001-11-19
申请人： ACCUCARD LTD , GUNN DAVID HUGH , MOUNTAIN DAVID GARRETT , HARYCKI EDWARD AIME
发明人： GUNN DAVID HUGH , MOUNTAIN DAVID GARRETT , HARYCKI EDWARD AIME
IPC分类号： G06Q40/00 , G07F19/00 , G06F17/60
CPC分类号： G06Q40/02

8. 发明申请

US20190114944A1 CUBE PUZZLE SOLVER 审中-公开
公开(公告)号：US20190114944A1
公开(公告)日：2019-04-18
申请号：US16099833
申请日：2017-11-22
申请人： David Garrett , Mehdi Hatamian
发明人： David Garrett , Mehdi Hatamian
IPC分类号： G09B19/22 , A63F9/08
摘要： A cube puzzle solver includes: a position sensing element; at least one user interface (UI) output; and a controller that receives position information from the position sensing element, determines a suggested move, and directs the at least one UI output to provide an indication associated with the suggested move. An automated method of determining a position of a cube puzzle solver includes: monitoring a set of sense pins; identifying rotation based on a change in state of at least one sense pin; identifying a face associated with the identified rotation; and updating a state of the cube puzzle solver based on the identified face and the identified rotation. A cube puzzle system includes: a cube puzzle device including: a wireless communication interface; and a user device communicatively coupled to the cube puzzle solver over the wireless communication interface.

9. 发明授权

US08807966B2 Pump motor protector with redundant shaft seal 有权
标题翻译：带有冗余轴封的泵电机保护器
公开(公告)号：US08807966B2
公开(公告)日：2014-08-19
申请号：US12669866
申请日：2008-07-18
申请人： Michael Hui Du , Arthur I. Watson , David Rowatt , Chad Bremner , Arunkumar Arumugam , David Garrett , Christopher Featherby , Ramez Guindi
发明人： Michael Hui Du , Arthur I. Watson , David Rowatt , Chad Bremner , Arunkumar Arumugam , David Garrett , Christopher Featherby , Ramez Guindi
IPC分类号： F04B39/00 , F04D29/10 , F04D13/10
CPC分类号： F04D13/10 , F04D29/106
摘要： An electric submersible pump device having a motor part, a pump part, and a protector part. The protector part includes redundant shaft seal parts.
摘要翻译：一种具有马达部件，泵部件和保护部件的电潜泵装置。保护器部分包括冗余轴密封部件。

10. 发明授权

US08774836B2 Method and system for optimized transfer of location database information 有权
标题翻译：用于优化位置数据库信息传输的方法和系统
公开(公告)号：US08774836B2
公开(公告)日：2014-07-08
申请号：US12732973
申请日：2010-03-26
申请人： Charles Abraham , Mark Buer , David Garrett , Jeyhan Karaoguz , David Lundgren , David Murray
发明人： Charles Abraham , Mark Buer , David Garrett , Jeyhan Karaoguz , David Lundgren , David Murray
IPC分类号： H04W24/00 , H04M11/04
CPC分类号： H04W64/003 , G01S5/0236 , G01S19/05 , H04W4/02 , H04W4/20 , H04W12/06 , H04W64/00
摘要： A servicing communication device may receive a subset of a location reference database that is maintained by a plurality of location servers, and may provide location related data to a mobile device that is communicatively coupled to the servicing communication device based on the received subset. The servicing communication device may determine capabilities and/or requirements of the mobile device, and may generate the location related data based on that determination. The servicing communication device may determine attributes and/or parameters that may affect determination of the subset of the location reference database. The subset of location reference database may be requested based on the determined attributes and/or parameters. The attributes and/or parameters may comprise a location of the servicing communication device. The servicing communication device may determine its location, directly based on GNSS transmissions and/or indirectly based on assisted GNSS (A-GNSS) data received from the plurality of location servers.
摘要翻译：服务通信设备可以接收由多个位置服务器维护的位置参考数据库的子集，并且可以基于所接收的子集向通信地耦合到服务通信设备的移动设备提供位置相关数据。服务通信设备可以确定移动设备的能力和/或要求，并且可以基于该确定来生成位置相关数据。服务通信设备可以确定可能影响位置参考数据库的子集的确定的属性和/或参数。可以基于所确定的属性和/或参数来请求位置参考数据库的子集。属性和/或参数可以包括服务通信设备的位置。服务通信设备可以直接基于GNSS传输和/或间接地基于从多个位置服务器接收到的辅助GNSS（A-GNSS）数据来确定其位置。

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