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1. 发明申请

US20150250729A1 PHARMACEUTICAL COMPOSITION 有权
标题翻译：药物组合物
公开(公告)号：US20150250729A1
公开(公告)日：2015-09-10
申请号：US14718595
申请日：2015-05-21
申请人： Moise Azria , Simon David Bateman , Anasuya Ashok Ghosh , Shoufeng Li , Alan Edward Royce
发明人： Moise Azria , Simon David Bateman , Anasuya Ashok Ghosh , Shoufeng Li , Alan Edward Royce
IPC分类号： A61K9/20 , A61K38/29
CPC分类号： A61K9/2013 , A61K9/2027 , A61K9/2054 , A61K9/2095 , A61K31/198 , A61K38/23 , A61K38/29
摘要： The present invention provides oral pharmaceutical compositions that enable the successful delivery of drugs in a pharmaceutically effective amount, particularly poly (amino acids) such as peptides, peptidomimetics and proteins. e.g. hormones to a subject via oral administration to accomplish the desired therapeutic effect. The oral pharmaceutical composition comprising a poly (amino acid) as the active ingredient, e.g. a peptide or protein, shows a rapid disintegration and/or dissolution such that the active ingredient is able to attain a therapeutic effect.
摘要翻译：本发明提供口服药物组合物，其能够以药学有效量成功递送药物，特别是聚（氨基酸）如肽，肽模拟物和蛋白质。例如通过口服给予受试者的激素以实现期望的治疗效果。包含聚（氨基酸）作为活性成分的口服药物组合物，例如，肽或蛋白质显示快速崩解和/或溶解，使得活性成分能够获得治疗效果。

2. 发明授权

US08664211B2 Modified amino acid for the inhibition of platelet aggregation 有权
标题翻译：改性氨基酸用于抑制血小板聚集
公开(公告)号：US08664211B2
公开(公告)日：2014-03-04
申请号：US13327129
申请日：2011-12-15
申请人： Simon David Bateman , Moise Azria
发明人： Simon David Bateman , Moise Azria
IPC分类号： A61K31/33
CPC分类号： A61K38/23 , A61K31/166 , A61K31/198 , A61K31/727 , A61K38/28 , A61K38/29 , A61K2300/00
摘要： A method of inhibiting blood platelet aggregation in a mammal is provided. The method comprises the administration of a platelet aggregation inhibiting amount of a modified amino acid or pharmaceutically acceptable salt thereof.
摘要翻译：提供了抑制哺乳动物血小板聚集的方法。该方法包括给予血小板聚集抑制量的修饰氨基酸或其药学上可接受的盐。

3. 发明申请

US20120106709A1 ACTIVE THERMAL CONTROL OF X-RAY TUBES 有权
标题翻译： X射线管的主动热控制
公开(公告)号：US20120106709A1
公开(公告)日：2012-05-03
申请号：US12915836
申请日：2010-10-29
申请人： Ron Kent Hockersmith , Michael Hebert , Ian Strider Hunt , David Bateman
发明人： Ron Kent Hockersmith , Michael Hebert , Ian Strider Hunt , David Bateman
IPC分类号： H01J35/12
CPC分类号： H05G1/36 , H05G1/54
摘要： The present embodiments relate to active thermal control of X-ray tubes, for example X-ray tubes used in CT imaging. In one embodiment, a system for thermal control of an X-ray tube is provided. The system includes an X-ray tube having an electron beam target, a rotary bearing supporting the target in rotation, and a coolant flow passage, at least a portion of the coolant flow passage being disposed in the center of the rotary bearing, and the coolant flow passage is configured to receive a coolant. The system also includes a coolant circulating system coupled to the coolant flow passage and configured to circulate the coolant thorough the coolant flow passage, and a control circuit coupled to the coolant circulating system and the rotary bearing, the control circuit being configured to control heat flow between components of the X-ray tube by regulating extraction of heat from the X-ray tube via the coolant and by regulating a rotation rate of the rotary bearing.
摘要翻译：本实施例涉及X射线管的主动热控制，例如用于CT成像的X射线管。在一个实施例中，提供了一种用于X射线管的热控制的系统。该系统包括具有电子束目标的X射线管，支撑目标旋转的旋转轴承和冷却剂流动通道，冷却剂流动通道的至少一部分设置在旋转轴承的中心，并且冷却剂流动通道构造成接收冷却剂。该系统还包括冷却剂循环系统，其耦合到冷却剂流动通道并且构造成使冷却剂循环通过冷却剂流动通道;以及控制电路，其耦合到冷却剂循环系统和旋转轴承，该控制电路被配置为控制热流通过调节通过冷却剂从X射线管提取热量并通过调节旋转轴承的旋转速度来控制X射线管的部件之间的距离。

4. 发明申请

US20090264367A1 5-CNAC AS ORAL DELIVERY AGENT FOR PARATHYROID HORMONE FRAGMENTS 审中-公开
标题翻译： 5-CNAC作为PARATHYROID HORMONE片剂的口服递送剂
公开(公告)号：US20090264367A1
公开(公告)日：2009-10-22
申请号：US12495966
申请日：2009-07-01
申请人： Moise Azria , Simon David Bateman
发明人： Moise Azria , Simon David Bateman
IPC分类号： A61K38/29 , A61P19/10
CPC分类号： A61K47/183 , A61K9/4858 , A61K31/198 , A61K38/29 , A61K2300/00
摘要： Pharmaceutical compositions for the effective oral delivery of a parathyroid hormone, PTH, as well as methods for administration of the compositions are provided. Additionally, methods for stimulating new bone formation and treating and/or preventing osteoporosis are also provided.
摘要翻译：提供了用于有效口服递送甲状旁腺激素（PTH）的药物组合物，以及给药组合物的方法。此外，还提供了刺激新骨形成和治疗和/或预防骨质疏松症的方法。

5. 发明授权

US07049283B2 Pharmaceutical compositions for the oral delivery of pharmacologically active agents 有权
公开(公告)号：US07049283B2
公开(公告)日：2006-05-23
申请号：US10006311
申请日：2001-12-04
申请人： Joseph M. Ault , Moise Azria , Simon David Bateman , Joseph Sikora , Gregory Sparta , Rebecca Fai-ying Yang , Jie Xiao
发明人： Joseph M. Ault , Moise Azria , Simon David Bateman , Joseph Sikora , Gregory Sparta , Rebecca Fai-ying Yang , Jie Xiao
IPC分类号： A01N37/18
CPC分类号： A61K9/2027 , A61K9/2013 , A61K9/2054 , A61K47/183
摘要： Solid pharmaceutical compositions suitable for the oral delivery of pharmacologically active agents, e.g. peptides, comprising a therapeutically-effective amount of a pharmacologically active agent; a crospovidone or povidone; and a delivery agent for said pharmacologically active agent are disclosed. The compositions provide excellent oral bioavailability of pharmacologically active agents, particularly calcitonin.

6. 发明申请

US20050199853A1 Vapor compression air conditioning or refrigeration system cleaning compositions and methods 失效
标题翻译：蒸气压缩空调或制冷系统清洗组合物及方法
公开(公告)号：US20050199853A1
公开(公告)日：2005-09-15
申请号：US11039625
申请日：2005-01-19
申请人： David Bateman
发明人： David Bateman
IPC分类号： B01F1/00 , C02F5/02 , C02F5/08 , C11D7/26 , C11D7/50 , C23G5/00 , C23G5/032 , F25B9/00 , F28G1/00
CPC分类号： C11D11/0041 , C11D7/266 , C11D7/5018 , C23G5/032
摘要： The present invention relates to compositions that are suitable for removing or reducing residue from a vapor compression air conditioning or refrigeration system consisting essentially of 1,1,1,2,2,3,4,5,5,5-decafluoropentane and polyol ester, and methods of using the composition.
摘要翻译：本发明涉及适用于从基本上由1,1,1,2,2,3,4,5,5,5-十氟戊烷和多元醇酯组成的蒸汽压缩空调或制冷系统中除去或还原残余物的组合物，以及使用该组合物的方法。

7. 发明申请

US20050152631A1 Conversion between optical and radio frequency signals 有权
标题翻译：光和射频信号之间的转换
公开(公告)号：US20050152631A1
公开(公告)日：2005-07-14
申请号：US10504009
申请日：2003-01-13
申请人： Patrick Labbe , Jean-Noel Patillon , David Bateman , Eric Toussaere
发明人： Patrick Labbe , Jean-Noel Patillon , David Bateman , Eric Toussaere
IPC分类号： G02F1/365 , G02F1/035 , G02F1/065 , H04B10/2575 , G02F1/01
CPC分类号： G02F1/065 , G02F1/0356 , H04B10/25752
摘要： A detector or a modulator for converting between optical and radio frequency signals comprising an optical guide (11 to 14) for propagating two optical signal components having frequencies that differ by an amount corresponding to a radio frequency and a microstrip radio signal guide (15, 16) for propagating a radio signal at the radio frequency, the microstrip radio signal guide being in travelling-wave coupling with an interaction one (14) of the optical guide comprising material in which interaction between the optical signal components and the radio signal occur. The microstrip radio signal guide element (15, 16) comprises an electrically conductive strip (15) juxtaposed with and extending along the interaction zone (14) on one side thereof and an electrically conductive ground plane (16) juxtaposed with and extending along the interaction zone (14) on an opposite side thereof. Transition radio signal guide elements (20,21) in the form of Vivaldi antennas extending transversely to the microstrip (15) connect the microstrip radio signal guide element (15,16) with a rectangular section wave-guide (18) and a matched load. Each of the transition radio signal guide elements (20, 21) comprises an opening of progressively varying width formed in the electrically conductive ground plane of the microstrip guide (16). Radio frequency signal resonators (24 to 27) extend the ends of the microstrip (15) and the small ends of the Vivaldi antennae.
摘要翻译：一种用于在光学和射频信号之间转换的检测器或调制器，包括用于传播具有与射频相应的频率不同的频率的两个光信号分量的光导体（11〜14）和微带无线电信号引导件（15,16 ），用于以射频传播无线电信号，所述微带无线电信号引导件与所述光导体的相互作用一（14）进行行波耦合，所述相互作用单元包括在所述光信号分量和所述无线电信号之间发生相互作用的材料。微带无线电信号引导元件（15,16）包括一个导电条（15），该导电条（15）在其一侧上与相互作用区（14）并置并延伸，并且导电接地平面（16）与相互作用并置并延伸区域（14）。以横向于微带线（15）延伸的Vivaldi天线形式的过渡无线电信号引导元件（20,21）将微带无线电信号引导元件（15,16）与矩形截面波导（18）和匹配负载。每个过渡无线电信号引导元件（20,21）包括在微带引导件（16）的导电接地平面中形成的逐渐变化的宽度的开口。射频信号谐振器（24至27）延伸微带（15）的端部和维瓦第二天线的小端。

8. 发明申请

US20050030165A1 Multiplex bus interface system and method for transmitting and receiving power and data 有权
标题翻译：多路总线接口系统及其发送和接收方法
公开(公告)号：US20050030165A1
公开(公告)日：2005-02-10
申请号：US10819729
申请日：2004-04-07
申请人： David Bateman , Matthew Bush
发明人： David Bateman , Matthew Bush
IPC分类号： H04B3/54 , H04M11/04
CPC分类号： H04B3/548 , H04B2203/5408 , H04B2203/5416 , H04B2203/5458 , H04B2203/547
摘要： A multiplex bus interface enables power and data to be transmitted and received on a two wire bus. Input and output devices operate with transceivers connected to the bus to communicate with each other by placing their data on the bus within specific time slots controlled by a controller, a clock module which broadcasts data to all connected transceivers. A pulsed power waveform provides power to the transceivers and data through pulse width modulation of the pulsed waveform. Data from the transceivers is transmitted during a time slot between power pulses. Data integrity is checked by the initiating input transceiver. Errors are reported at the end of a broadcast cycle. Output transceivers use the data as appropriate for the device and condition being monitored or controlled.
摘要翻译：复用总线接口使电源和数据能够在两线总线上传输和接收。输入和输出设备通过连接到总线的收发器进行操作，通过将控制器控制的特定时隙内的数据放置在总线上，将数据相互通信，时钟模块向所有连接的收发器广播数据。脉冲功率波形通过脉冲波形的脉冲宽度调制为收发器和数据提供电力。来自收发器的数据在功率脉冲之间的时隙中传输。启动输入收发器检查数据完整性。在广播周期结束时报告错误。输出收发器使用适合于监视或控制的设备和状况的数据。

9. 发明申请

US20200177008A1 MOBILE POWER SYSTEM WITH BIDIRECTIONAL AC-DC CONVERTER AND RELATED PLATFORMS AND METHODS 审中-公开
公开(公告)号：US20200177008A1
公开(公告)日：2020-06-04
申请号：US16701517
申请日：2019-12-03
申请人： Alex Tiedtke , David Bateman
发明人： Alex Tiedtke , David Bateman
IPC分类号： H02J7/00 , B60R16/033
摘要： A mobile power system may include a bidirectional AC-DC converter configured to convert a grid AC signal to a power limited DC charging signal with a threshold level, a battery module configured to provide a DC power signal, and a controller coupled to the battery module and the bidirectional AC-DC converter and configured to selectively switch the bidirectional AC-DC converter between a first state and a second state. The first state may include, when a load power level is less than the threshold level, concurrently charging the battery module using the power limited DC charging signal and delivering the grid AC signal to a load. The second state may include, when the load power level is greater than the threshold level, concurrently converting the DC power signal with the bidirectional AC-DC converter into a battery AC signal for delivery to the load, and delivering the grid AC signal to the load.

10. 发明授权

US09272040B2 5-CNAC as oral delivery agent for parathyroid hormone fragments 有权
公开(公告)号：US09272040B2
公开(公告)日：2016-03-01
申请号：US13327114
申请日：2011-12-15
申请人： Moise Azria , Simon David Bateman
发明人： Moise Azria , Simon David Bateman
IPC分类号： A61K38/29 , A61K47/18 , A61K9/48 , A61K31/198
CPC分类号： A61K47/183 , A61K9/4858 , A61K31/198 , A61K38/29 , A61K2300/00
摘要： Pharmaceutical compositions for the effective oral delivery of a parathyroid hormone, PTH, as well as methods for administration of the compositions are provided. Additionally, methods for stimulating new bone formation and treating and/or preventing osteoporosis are also provided.

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