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1. 发明授权

US08118857B2 Medical articles that stimulate endothelial cell migration 失效
标题翻译：刺激内皮细胞迁移的医学文章
公开(公告)号：US08118857B2
公开(公告)日：2012-02-21
申请号：US11947150
申请日：2007-11-29
申请人： Daniel VanCamp , Rajesh Radhakrishnan , Eric Nielson , Verivada Chandrasekaran
发明人： Daniel VanCamp , Rajesh Radhakrishnan , Eric Nielson , Verivada Chandrasekaran
IPC分类号： A61F2/82
CPC分类号： A61N1/326 , A61L27/04 , A61L27/50 , A61L31/022 , A61L31/14 , A61N1/30
摘要： A medical article that includes (a) an electronically conductive substrate having a specific conductivity of at least 1 μS/cm and (b) a galvanic couple that includes a first member and a second member arranged in sufficient proximity to each other to generate a localized electric field under physiological conditions. The first and second members are selected such that the galvanic couple exhibits an average plateau current density of at least 25 microamps/cm2 when short circuited in a zero resistance ammeter test at room temperature using a saline electrolyte.
摘要翻译：一种医疗制品，其包括（a）具有至少1μS/ cm的比电导率的电子导电基底和（b）包括彼此足够接近地布置的第一构件和第二构件的电偶，以产生局部生理条件下的电场。选择第一和第二构件，使得当在室温下使用盐水电解质的零电阻电流表试验中短路时，电偶对的平均平均电流密度至少为25微安/ cm2。

2. 发明申请

US20090143856A1 MEDICAL ARTICLES THAT STIMULATE ENDOTHELIAL CELL MIGRATION 失效
标题翻译：刺激内皮细胞迁移的医学文章
公开(公告)号：US20090143856A1
公开(公告)日：2009-06-04
申请号：US11947150
申请日：2007-11-29
申请人： Daniel VanCamp , Rajesh Radhakrishnan , Eric Nielson , Verivada Chandrasekaran
发明人： Daniel VanCamp , Rajesh Radhakrishnan , Eric Nielson , Verivada Chandrasekaran
IPC分类号： A61F2/82
CPC分类号： A61N1/326 , A61L27/04 , A61L27/50 , A61L31/022 , A61L31/14 , A61N1/30
摘要： A medical article that includes (a) an electronically conductive substrate having a specific conductivity of at least 1 μS/cm and (b) a galvanic couple that includes a first member and a second member arranged in sufficient proximity to each other to generate a localized electric field under physiological conditions. The first and second members are selected such that the galvanic couple exhibits an average plateau current density of at least 25 microamps/cm2 when short circuited in a zero resistance ammeter test at room temperature using a saline electrolyte.
摘要翻译：一种医疗制品，其包括（a）具有至少1μS/ cm的比电导率的电子导电基底和（b）包含第一构件和第二构件的电偶，所述第一构件和第二构件布置成彼此足够接近以产生局部生理条件下的电场。选择第一和第二构件，使得当在室温下使用盐水电解质的零电阻电流表试验中短路时，电偶对的平均平均电流密度至少为25微安/ cm2。

3. 发明授权

US07927346B2 Diversion device to increase cerebral blood flow 有权
标题翻译：引流装置增加脑血流量
公开(公告)号：US07927346B2
公开(公告)日：2011-04-19
申请号：US10937916
申请日：2004-09-10
申请人： Daniel VanCamp , Eric D. Nielson
发明人： Daniel VanCamp , Eric D. Nielson
IPC分类号： A61M29/00
CPC分类号： A61B17/12136 , A61B17/12022 , A61B17/12036 , A61B17/12109 , A61B17/12172 , A61B2017/00004 , A61B2017/00243 , A61B2017/00575 , A61B2017/00579 , A61B2017/00592 , A61B2017/00597 , A61B2017/00615
摘要： Methods and devices provide for temporary partial aortic occlusion to achieve diversion of blood flow to the brain in patients suffering from cerebral ischemia. The device can include an expandable frame with a membrane mounted on a first portion of the frame. The membrane can have at least one opening. In some embodiments, the membrane has an outer region and an inner region, and an opening in the inner region. In use, the frame can expand to conform to the inner walls of the aorta and the membrane can at least partially occlude the aorta thereby increasing cerebral perfusion. The frame can include one or more anchors to aid in maintaining the device in position against the arterial blood flow pressure.
摘要翻译：方法和装置提供临时部分主动脉闭塞以在患有脑缺血的患者中实现血流向脑的转移。该装置可以包括具有安装在框架的第一部分上的膜的可扩张框架。膜可以具有至少一个开口。在一些实施例中，膜具有外部区域和内部区域以及内部区域中的开口。在使用中，框架可以膨胀以符合主动脉的内壁，并且膜可以至少部分地阻塞主动脉，从而增加脑灌注。框架可以包括一个或多个锚固件，以帮助将装置保持在适当位置以抵抗动脉血流压力。

4. 发明申请

US20050203606A1 Stent system for preventing restenosis 审中-公开
标题翻译：用于预防再狭窄的支架系统
公开(公告)号：US20050203606A1
公开(公告)日：2005-09-15
申请号：US10797737
申请日：2004-03-09
申请人： Daniel VanCamp
发明人： Daniel VanCamp
IPC分类号： A61F2/00 , A61F2/82 , A61F2/06
CPC分类号： A61F2/82 , A61F2/852 , A61F2/958 , A61F2250/0039 , A61F2250/0048 , A61F2250/0063
摘要： A system for treating a body lumen is disclosed. The system comprises an outer stent and an inner stent disposed within the lumen of the outer stent. At least one end of the inner stent extends outside of the lumen of the outer stent, so that the end of the inner stent contacts and conforms to the body lumen wall that is adjacent the end of the outer stent. A coating can be disposed on a surface, preferably the outer surface, of the inner stent. The coating contains a therapeutic substance that may be released into the body lumen wall to help in preventing restenosis. Also disclosed is a stent having a balloon-expandable portion connected to a self-expanding portion. Methods for deploying the system and the stent are also disclosed.
摘要翻译：公开了一种用于治疗体腔的系统。该系统包括外支架和设置在外支架的内腔内的内支架。内支架的至少一端延伸到外支架的腔的外侧，使得内支架的端部接触并且与邻近外支架端部的体腔壁相吻合。可以在内支架的表面（优选外表面）上设置涂层。该涂层含有可释放到体腔壁中以帮助预防再狭窄的治疗物质。还公开了一种支架，其具有连接到自膨胀部分的球囊膨胀部分。还公开了用于展开系统和支架的方法。

5. 发明申请

US20110022162A1 ENDOPROSTHESES 审中-公开
公开(公告)号：US20110022162A1
公开(公告)日：2011-01-27
申请号：US12508092
申请日：2009-07-23
申请人： Rajesh Radhakishnan , Liliana Atanasoska , Daniel VanCamp
发明人： Rajesh Radhakishnan , Liliana Atanasoska , Daniel VanCamp
IPC分类号： A61F2/06 , B44C1/22 , C25D11/00
CPC分类号： C25D3/50 , A61F2/91 , C25D5/18 , C25D5/48 , C25D11/34
摘要： An endoprosthesis includes an endoprosthesis wall that includes a ceramic coating and a polymer coating containing a therapeutic agent. A ceramic coating can be formed on the wall by electrochemical deposition. Cyclic voltammetry can be conducted to modify the density of the hydroxyl groups on the surface of the ceramic coating.
摘要翻译：内置假体包括内置假体壁，其包括陶瓷涂层和含有治疗剂的聚合物涂层。可以通过电化学沉积在壁上形成陶瓷涂层。可以进行循环伏安法来改变陶瓷涂层表面上的羟基的密度。

6. 发明申请

US20090118823A1 ENDOPROSTHESIS WITH POROUS RESERVOIR 审中-公开
标题翻译：与多孔储层结合
公开(公告)号：US20090118823A1
公开(公告)日：2009-05-07
申请号：US11934421
申请日：2007-11-02
申请人： Liliana Atanasoska , Daniel VanCamp
发明人： Liliana Atanasoska , Daniel VanCamp
IPC分类号： A61F2/06
CPC分类号： A61L31/16 , A61L31/022 , A61L31/146 , A61L2300/00
摘要： An endoprosthesis such as a coronary stent includes a porous metal reservoir of drug, e.g. directly in the body of the stent. And a method of loading drug into the porous reservoir includes applying an electrical potential to the endoprosthesis.
摘要翻译：诸如冠状动脉支架的内假体包括药物的多孔金属储库，例如，直接在体内的支架。并且将药物装载到多孔容器中的方法包括向内假体施加电势。

7. 发明申请

US20090118818A1 ENDOPROSTHESIS WITH COATING 审中-公开
标题翻译：涂层涂层
公开(公告)号：US20090118818A1
公开(公告)日：2009-05-07
申请号：US11934296
申请日：2007-11-02
申请人： Aaron Foss , Raed Rizq , Daniel Vancamp
发明人： Aaron Foss , Raed Rizq , Daniel Vancamp
IPC分类号： A61F2/82 , A61L27/28
CPC分类号： A61L31/088 , A61L31/14
摘要： An endoprosthesis such as a coronary stent includes a surface region that defines a depression in the form of a channel, the depression having an interior surface, and an enhanced roughness on the interior surface.
摘要翻译：诸如冠状动脉支架的内假体包括限定通道形式的凹陷的表面区域，凹陷具有内表面，并且在内表面上具有增强的粗糙度。

8. 发明申请

US20060058833A1 Diversion device to increase cerebral blood flow 有权
标题翻译：引流装置增加脑血流量
公开(公告)号：US20060058833A1
公开(公告)日：2006-03-16
申请号：US10937916
申请日：2004-09-10
申请人： Daniel VanCamp , Eric Nielson
发明人： Daniel VanCamp , Eric Nielson
IPC分类号： A61M29/00
CPC分类号： A61B17/12136 , A61B17/12022 , A61B17/12036 , A61B17/12109 , A61B17/12172 , A61B2017/00004 , A61B2017/00243 , A61B2017/00575 , A61B2017/00579 , A61B2017/00592 , A61B2017/00597 , A61B2017/00615
摘要： Methods and devices provide for temporary partial aortic occlusion to achieve diversion of blood flow to the brain in patients suffering from cerebral ischemia. The device includes an expandable frame and membrane that is inserted into the aorta to partially occlude blood flow.
摘要翻译：方法和装置提供临时部分主动脉闭塞以在患有脑缺血的患者中实现血流向脑的转移。该装置包括可扩张的框架和膜，其插入主动脉以部分阻塞血流。

9. 发明授权

US07153411B2 Method for cleaning and polishing metallic alloys and articles cleaned or polished thereby 有权
标题翻译：清洁和抛光由此清洗或抛光的金属合金和制品的方法
公开(公告)号：US07153411B2
公开(公告)日：2006-12-26
申请号：US10748493
申请日：2003-12-30
申请人： Steve Larson , Daniel VanCamp , Nielsen Eric
发明人： Steve Larson , Daniel VanCamp , Nielsen Eric
IPC分类号： C25F3/22 , C25F3/24 , C25F3/26 , C25F1/00
CPC分类号： C25F3/22 , A61L31/022 , A61L31/14 , C25F1/04
摘要： A method of cleaning and polishing an alloy comprising at least one noble metal and at least one non-noble metal, the method including the steps of submerging said alloy in an electrolytic acidic bath comprising at least one chelating or complexing agent including sulfur, and applying a multiple pulse periodic reverse waveform, and articles cleaned and/or polished thereby.
摘要翻译：一种清洗和抛光包含至少一种贵金属和至少一种非贵金属的合金的方法，所述方法包括以下步骤：将所述合金浸入包含至少一种包含硫的螯合剂或络合剂的电解酸性浴中，并施加多脉冲周期性反向波形，以及由此清洁和/或抛光的制品。

10. 发明申请

US20050145508A1 Method for cleaning and polishing steel-plantinum alloys 有权
标题翻译：钢铁合金清洗和抛光方法
公开(公告)号：US20050145508A1
公开(公告)日：2005-07-07
申请号：US10748493
申请日：2003-12-30
申请人： Steve Larsen , Daniel VanCamp , Eric Nielson
发明人： Steve Larsen , Daniel VanCamp , Eric Nielson
IPC分类号： A61L31/02 , A61L31/14 , C25D1/04 , C25F1/04 , C25F3/22 , B23H3/00
CPC分类号： C25F3/22 , A61L31/022 , A61L31/14 , C25F1/04
摘要： A method of cleaning and polishing an alloy comprising at least one noble metal and at least one non-noble metal, the method including the steps of submerging said alloy in an electrolytic acidic bath comprising at least one chelating or complexing agent including sulfur, and applying a multiple pulse periodic reverse waveform, and articles cleaned and/or polished thereby.
摘要翻译：一种清洗和抛光包含至少一种贵金属和至少一种非贵金属的合金的方法，所述方法包括以下步骤：将所述合金浸入包含至少一种包含硫的螯合剂或络合剂的电解酸性浴中，并施加多脉冲周期性反向波形，以及由此清洁和/或抛光的制品。

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