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1. 发明专利

AT84149T 未知
公开(公告)号：AT84149T
公开(公告)日：1993-01-15
申请号：AT88906854
申请日：1988-08-03
申请人： DAROUGAR SOHRAB
发明人： DAROUGAR SOHRAB
IPC分类号： G01N21/78 , G01N21/64 , G01N33/53 , G01N33/533 , G01N33/543 , G01N33/58
摘要： A luminescent assay process characterized in that images of a selectively luminescent sample are recorded on a photographic film by macrophotography.

2. 发明专利

AT287256T 未知
公开(公告)号：AT287256T
公开(公告)日：2005-02-15
申请号：AT00973036
申请日：2000-11-03
申请人： DAROUGAR SOHRAB , DAROUGAR DAYSHAD
发明人： DAROUGAR SOHRAB , DAROUGAR DAYSHAD
IPC分类号： A61F9/00 , A61K9/00
摘要： A flexible ocular insert device adapted for the controlled sustained release of a drug upon insertion into the upper or lower fornix of the eye. The device comprises an elongate body of a polymeric material including two end portions, wherein the body contains a pharmaceutically active ingredient, and wherein the device has a length of at least 8 mm and a maximum diameter not exceeding 1.9 mm. The device is sufficiently flexible to allow it to bend along the curvature of the eye within the upper or lower fornix upon its being positioned so that the longitudinal axis of the device is generally parallel to the transverse diameter of the eyeball, and the device does not extend onto any visible portion of the eyeball. Each of the end portions of the device is tapered towards the extremities of the device.

3. 发明申请

WO1995001764A2 OCULAR INSERT WITH ANCHORING PROTRUSIONS 审中-公开
标题翻译：具有锚定推理的OCULAR插入
公开(公告)号：WO1995001764A2
公开(公告)日：1995-01-19
申请号：PCT/US1994007136
申请日：1994-06-20
申请人： DAROUGAR, Sohrab , WEINER, Alan, L. , BHATT, Padmanabh, Pravinchandra , RAUL, Victor, Albert , GANTNER, David, Clayton
IPC分类号： A61F09/00
CPC分类号： A61F9/0017 , A61K9/0051
摘要： A flexible ocular insert device adapted for the controlled sustained release of an ophthalmic drug into the eye. In one embodiment, the device includes an elongated body of a polymeric material in the form of a rod or tube containing a pharmaceutically active ingredient and with at least two anchoring protrusions extending radially outwardly from the body. The device has a length of at least 8 mm and the diameter of its body portion including the protrusions does not exceed 1.9 mm. The sustained release mechanism may, for example, be by diffusion or by osmosis or bioerosion. The insert device is advantageously inserted into the upper or lower fornix of the eye so as to be independent of movement of the eye by virtue of the fornix anatomy. The protrusions may be of various shapes such as, for example, ribs (76), screw threads (86), dimples or bumps (92), truncated cone-shaped segments (102) or winding braid segments (113). In a further embodiment, the polymeric material for the body is selected as one which swells in a liquid environment. Thus a device of smaller initial size may be employed. The present insert device is of a size and configuration such that, upon insertion into the upper or lower fornix, the device remains out of the field of vision so as to be well retained in place and imperceptible by a patient over a prolonged period of use. The device can be retained in the upper or lower fornix for 7 to 14 days or longer.
摘要翻译：一种柔性眼部插入装置，适于将眼药物的受控持续释放到眼睛中。在一个实施方案中，该装置包括呈杆形或管状形式的聚合物材料的细长体，其包含药物活性成分，并具有至少两个从身体径向向外延伸的锚定突起。该装置具有至少8mm的长度，并且其主体部分包括突起的直径不超过1.9mm。持续释放机制可以例如通过扩散或渗透或生物侵蚀。插入装置有利地插入到眼睛的上部或下部穹窿中，以便凭借穹窿解剖结构独立于眼睛的移动。突起可以是各种形状，例如肋（76），螺纹（86），凹坑或凸起（92），截头圆锥形段（102）或卷绕编织段（113）。在另一个实施方案中，用于身体的聚合物材料选择为在液体环境中溶胀的聚合物材料。因此，可以采用较小初始尺寸的装置。本插入装置的尺寸和构造使得在插入上部或下部穹窿中时，该装置保持离开视野，以便在长时间的使用中被良好地保持在适当位置并且被患者察觉不到。该装置可以保留在上，下穹顶7至14天或更长时间。

4. 发明申请

WO9501764A3 OCULAR INSERT WITH ANCHORING PROTRUSIONS 审中-公开
标题翻译：具有锚定推理的OCULAR插入
公开(公告)号：WO9501764A3
公开(公告)日：1995-03-02
申请号：PCT/US9407136
申请日：1994-06-20
申请人： DAROUGAR SOHRAB , WEINER ALAN L , BHATT PADMANABH PRAVINCHANDRA , RAUL VICTOR ALBERT , GANTNER DAVID CLAYTON
发明人： DAROUGAR SOHRAB , WEINER ALAN L , BHATT PADMANABH PRAVINCHANDRA , RAUL VICTOR ALBERT , GANTNER DAVID CLAYTON
IPC分类号： A61F9/007 , A61F9/00 , A61K9/00 , B82B1/00
CPC分类号： A61F9/0017 , A61K9/0051
摘要： A flexible ocular insert device adapted for the controlled sustained release of an ophthalmic drug into the eye. In one embodiment, the device includes an elongated body of a polymeric material in the form of a rod or tube containing a pharmaceutically active ingredient and with at least two anchoring protrusions extending radially outwardly from the body. The device has a length of at least 8 mm and the diameter of its body portion including the protrusions does not exceed 1.9 mm. As shown in Figure 7, the device (70) with ribbed configuration has circular cylindrical walls (72) with domed end portions (74). A series of arcuate shaped ribs (76), of circular, toroidal cross section, are provided at intervals along the length of the device (70).

5. 发明专利

DE60017580D1 未知
公开(公告)号：DE60017580D1
公开(公告)日：2005-02-24
申请号：DE60017580
申请日：2000-11-03
申请人： DAROUGAR SOHRAB , DAROUGAR DAYSHAD
发明人： DAROUGAR SOHRAB , DAROUGAR DAYSHAD
IPC分类号： A61F9/00 , A61K9/00
摘要： A flexible ocular insert device adapted for the controlled sustained release of a drug upon insertion into the upper or lower fornix of the eye. The device comprises an elongate body of a polymeric material including two end portions, wherein the body contains a pharmaceutically active ingredient, and wherein the device has a length of at least 8 mm and a maximum diameter not exceeding 1.9 mm. The device is sufficiently flexible to allow it to bend along the curvature of the eye within the upper or lower fornix upon its being positioned so that the longitudinal axis of the device is generally parallel to the transverse diameter of the eyeball, and the device does not extend onto any visible portion of the eyeball. Each of the end portions of the device is tapered towards the extremities of the device.

6. 发明专利

GB9726920D0 Immunoassay system 未知
公开(公告)号：GB9726920D0
公开(公告)日：1998-02-18
申请号：GB9726920
申请日：1997-12-19
申请人： DAROUGAR SOHRAB

7. 发明专利

GB9626100D0 Immunoassay system 未知
公开(公告)号：GB9626100D0
公开(公告)日：1997-02-05
申请号：GB9626100
申请日：1996-12-16
申请人： DAROUGAR SOHRAB

8. 发明专利

CA2165071A1 Ocular Insert with Anchoring Protrusions 未知
公开(公告)号：CA2165071A1
公开(公告)日：1995-01-19
申请号：CA2165071
申请日：1994-06-20
申请人： DAROUGAR SOHRAB , WEINER ALAN L , BHATT PADMANABH PRAVINCHANDRA , RAUL VICTOR ALBERT , GANTNER DAVID CLAYTON
发明人： DAROUGAR SOHRAB , WEINER ALAN L , BHATT PADMANABH PRAVINCHANDRA , RAUL VICTOR ALBERT , GANTNER DAVID CLAYTON
IPC分类号： A61F9/007 , A61F9/00 , A61K9/00 , B82B1/00 , A61M31/00
摘要： A flexible ocular insert device adapted for the controlled sustained release of an ophthalmic drug into the eye. In one embodiment, the device includes an elongated body of a polymeric material in the form of a rod or tube containing a pharmaceutically active ingredient and with at least two anchoring protrusions extending radially outwardly from the body. The device has a length of at least 8 mm and the diameter of its body portion including the protrusions does not exceed 1.9 mm. The sustained release mechanism may, for example, be by diffusion or by osmosis or bioerosion. The insert device is advantageously inserted into the upper or lower fornix of the eye so as to be independent of movement of the eye by virtue of the fornix anatomy. The protrusions may be of various shapes such as, for example, ribs, screw threads, dimples or bumps, truncated cone-shaped segments or winding braid segments. In a further embodiment, the polymeric material for the body is selected as one which swells in a liquid environment. Thus a device of smaller initial size may be employed. The present insert device is of a size and configuration such that, upon insertion into the upper or lower fornix, the device remains out of the field of vision so as to be well retained in place and imperceptible by a patient over a prolonged period of use. The device can be retained in the upper or lower fornix for 7 to 14 days or longer.

9. 发明专利

DE382734T1 未知
公开(公告)号：DE382734T1
公开(公告)日：1991-02-28
申请号：DE88906854
申请日：1988-08-03
申请人： DAROUGAR, SOHRAB, CROYDON, GB
发明人： DAROUGAR, SOHRAB, CROYDON, GB
IPC分类号： G01N21/78 , G01N21/64 , G01N33/53 , G01N33/533 , G01N33/543 , G01N33/58
摘要： A luminescent assay process characterized in that images of a selectively luminescent sample are recorded on a photographic film by macrophotography.

10. 发明专利

GB9026888D0 OCULAR INSERT FOR THE FORNIX 未知
公开(公告)号：GB9026888D0
公开(公告)日：1991-01-30
申请号：GB9026888
申请日：1990-12-11
申请人： DAROUGAR SOHRAB

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