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1. 发明授权

US07316701B2 Three dimensional, low friction vasoocclusive coil, and method of manufacture 失效
标题翻译：三维，低摩擦血管闭塞线圈及其制造方法
公开(公告)号：US07316701B2
公开(公告)日：2008-01-08
申请号：US10664001
申请日：2003-09-16
申请人： David A. Ferrera , Daniel Kurz , Peter Wilson , Crystal K. Sein-Lwyn , Lok A. Lei , Joseph A. Horton
发明人： David A. Ferrera , Daniel Kurz , Peter Wilson , Crystal K. Sein-Lwyn , Lok A. Lei , Joseph A. Horton
IPC分类号： A61M29/00
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12145 , A61B2017/00526 , A61B2017/00867 , A61F2/01 , A61F2002/30092 , A61F2210/0014 , A61L31/022 , A61L31/048 , A61L31/06 , B29C53/76 , B29C53/821 , B29C61/00 , B29K2029/00 , B29L2031/753 , B29L2031/7734 , C08L27/18 , C08L77/00 , C08L67/00
摘要： The three dimensional, low friction vasoocclusive coil has a portion that is three dimensionally box or cubed shaped. The three dimensional box or cubed shaped portion will form a basket for filling the anatomical cavity at the site in the vasculature to be treated. The vasoocclusive device is formed from at least one strand of a flexible material formed to have a first inoperable, substantially linear configuration for insertion into and through a catheter or cannula to a desired portion of the vasculature to be treated, and a second operable, three dimensional configuration for occluding the desired portion of the vasculature to be treated. The vasoocclusive coil may optionally include a portion that is substantially J-shaped or helically shaped, for filling and reinforcing the three dimensional portion.
摘要翻译：三维低摩擦血管收缩线圈具有三维立方体形状的部分。三维盒或立方形部分将形成用于在待治疗的脉管系统中的位置处填充解剖腔的篮。血管闭塞装置由柔性材料的至少一根股形成，以形成为具有用于插入导管或插管并穿过导管或套管至待治疗的脉管系统的期望部分的第一不可操作的基本线性构造，以及第二可操作的三用于封闭待治疗的脉管系统的期望部分的三维构型。血管收缩性线圈可以可选地包括基本上为J形或螺旋形的部分，用于填充和加强三维部分。

2. 发明授权

US06171326B2 Three dimensional, low friction vasoocclusive coil, and method of manufacture 有权
标题翻译：三维，低摩擦血管闭塞线圈及其制造方法
公开(公告)号：US06171326B2
公开(公告)日：2001-01-09
申请号：US09140495
申请日：1998-08-27
申请人： David A. Ferrera , Daniel R. Kurz , Peter Wilson , Crystal K. Sein-Lwyn , Lok A. Lei
发明人： David A. Ferrera , Daniel R. Kurz , Peter Wilson , Crystal K. Sein-Lwyn , Lok A. Lei
IPC分类号： A61M2900
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12145
摘要： The three dimensional, low friction vasoocclusive coil has a distal portion that is three dimensionally shaped, and a proximal portion that is linear or helically shaped. The distal three dimensional portion will form a basket for filling the anatomical cavity at the site in the vasculature to be treated, while the proximal portion will fill and reinforce the basket. The vasoocclusive device is formed from at least one strand of a flexible material formed to have an a first inoperable, substantially linear configuration for insertion into and through a catheter or cannula to a desired portion of the vasculature to be treated, and a second operable, three dimensional configuration for occluding the desired portion of the vasculature to be treated. The vasoocclusive device has a distal portion having a second operable, three dimensional shape for filing the anatomical cavity at the site in the vasculature to be treated, and a proximal portion having a second operable, substantially linear shape for filling and reinforcing the distal, three dimensional shaped portion when it is implanted at the site in the vasculature to be treated. Mandrels are provided for use in the method of making the vasoocclusive device.
摘要翻译：三维低摩擦血管收缩性线圈具有三维形状的远侧部分，以及线性或螺旋状的近端部分。远端三维部分将形成一个篮，用于在待治疗的脉管系统中的位置处填充解剖腔，而近端部分将填充并加强篮。血管闭塞装置由柔性材料的至少一根股形成，以形成为具有用于插入导管或插管并穿过导管或插管到待治疗的脉管系统的期望部分的第一不可操作的基本上线性的构型，以及第二可操作的，用于封闭待治疗的脉管系统的期望部分的三维构型。血管收缩装置具有远端部分，其具有第二可操作的三维形状，用于在待治疗的脉管系统中的位置处填充解剖腔，以及具有第二可操作的基本线性形状的近端部分，用于填充和加强远端，三当植入在待治疗的脉管系统中的位置处时，其尺寸形状部分。心轴被提供用于制造血管收缩装置的方法。

3. 发明授权

US06638291B1 Three dimensional, low friction vasoocclusive coil, and method of manufacture 失效
标题翻译：三维，低摩擦血管闭塞线圈及其制造方法
公开(公告)号：US06638291B1
公开(公告)日：2003-10-28
申请号：US09590794
申请日：2000-06-08
申请人： David A. Ferrera , Daniel Kurz , Peter Wilson , Crystal K. Sein-Lwyn , Lok A. Lei , Joseph A. Horton
发明人： David A. Ferrera , Daniel Kurz , Peter Wilson , Crystal K. Sein-Lwyn , Lok A. Lei , Joseph A. Horton
IPC分类号： A61M2900
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12145 , A61B2017/00526 , A61B2017/00867 , A61F2/01 , A61F2002/30092 , A61F2210/0014 , A61L31/022 , A61L31/048 , A61L31/06 , B29C53/76 , B29C53/821 , B29C61/00 , B29K2029/00 , B29L2031/753 , B29L2031/7734 , C08L27/18 , C08L77/00 , C08L67/00
摘要： The three dimensional, low friction vasoocclusive coil has a portion that is three dimensionally box or cubed shaped. The three dimensional box or cubed shaped portion will form a basket for filling the anatomical cavity at the site in the vasculature to be treated. The vasoocclusive device is formed from at least one strand of a flexible material formed to have a first inoperable, substantially linear configuration for insertion into and through a catheter or cannula to a desired portion of the vasculature to be treated, and a second operable, three dimensional configuration for occluding the desired portion of the vasculature to be treated. The vasoocclusive coil may optionally include a portion that is substantially J-shaped or helically shaped, for filling and reinforcing the three dimensional portion.
摘要翻译：三维低摩擦血管收缩线圈具有三维立方体形状的部分。三维盒或立方形部分将形成用于在待治疗的脉管系统中的位置处填充解剖腔的篮。血管闭塞装置由柔性材料的至少一根股形成，以形成为具有用于插入导管或插管并穿过导管或套管至待治疗的脉管系统的期望部分的第一不可操作的基本线性构型，以及第二可操作的三用于封闭待治疗的脉管系统的期望部分的三维构型。血管收缩性线圈可以可选地包括基本上为J形或螺旋形的部分，用于填充和加强三维部分。

4. 发明授权

US08790363B2 Three dimensional, low friction vasoocclusive coil, and method of manufacture 有权
标题翻译：三维，低摩擦血管闭塞线圈及其制造方法
公开(公告)号：US08790363B2
公开(公告)日：2014-07-29
申请号：US11436200
申请日：2006-05-17
申请人： David A. Ferrera , Daniel Kurz , Peter Wilson , Crystal K. Sein-Lwyn , Lok A. Lei , Joseph A. Horton
发明人： David A. Ferrera , Daniel Kurz , Peter Wilson , Crystal K. Sein-Lwyn , Lok A. Lei , Joseph A. Horton
IPC分类号： A61M29/00
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12145 , A61B2017/1205 , A61B2017/12072 , A61B2017/12077
摘要： The three dimensional, low friction vasoocclusive coil has a portion that is three dimensionally box or cubed shaped. The three dimensional box or cubed shaped portion will form a basket for filling the anatomical cavity at the site in the vasculature to be treated. The vasoocclusive device is formed from at least one strand of a flexible material formed to have a first inoperable, substantially linear configuration for insertion into and through a catheter or cannula to a desired portion of the vasculature to be treated, and a second operable, three dimensional configuration for occluding the desired portion of the vasculature to be treated. The vasoocclusive coil may optionally include a portion that is substantially J-shaped or helically shaped, for filling and reinforcing the three dimensional portion.
摘要翻译：三维低摩擦血管收缩线圈具有三维立方体形状的部分。三维盒或立方形部分将形成用于在待治疗的脉管系统中的位置处填充解剖腔的篮。血管闭塞装置由柔性材料的至少一根股形成，以形成为具有用于插入导管或插管并穿过导管或套管至待治疗的脉管系统的期望部分的第一不可操作的基本线性构型，以及第二可操作的三用于封闭待治疗的脉管系统的期望部分的三维构型。血管收缩性线圈可以可选地包括基本上为J形或螺旋形的部分，用于填充和加强三维部分。

5. 发明授权

US06296622B1 Endoluminal device delivery system using axially recovering shape memory material 有权
标题翻译：使用轴向恢复形状记忆材料的腔内装置输送系统
公开(公告)号：US06296622B1
公开(公告)日：2001-10-02
申请号：US09218117
申请日：1998-12-21
申请人： Daniel R. Kurz , Rose Y. Wong , Crystal K. Sein-Lwyn , David A. Ferrera , Lok A. Lei , Nicholas C. Debeer
发明人： Daniel R. Kurz , Rose Y. Wong , Crystal K. Sein-Lwyn , David A. Ferrera , Lok A. Lei , Nicholas C. Debeer
IPC分类号： A61M1100
CPC分类号： A61B17/12022 , A61B17/1214 , A61B2017/00867 , A61B2017/1205 , A61B2017/12072 , A61B2017/12077 , A61B2018/00005 , A61F2/95
摘要： The endoluminal device delivery system and method for delivering an endoluminal device within a body lumen uses shape memory material in the form of a tubular collar to engage the endoluminal device during delivery to the desired location. The endoluminal device is engaged internally within the tubular collar either mechanically by crimping the tubular collar around a portion of the endoluminal device, or through an adhesive bond. The tubular collar can be crimped about a rounded portion of the stem of the endoluminal device. Once the endoluminal device is maneuvered through the body lumens to the desired location, it is decoupled from the delivery system by applying heat to the tubular collar of shape memory material. When the tubular collar has been heated to a sufficient temperature, it will transition to a rubbery state and shrink in length, thereby retracting completely back on to the optical fiber, causing the distal end of the optical fiber to engage the endoluminal device and dislodge it from the tubular collar. An interlocking assembly can also be utilized at the stem portion of the endoluminal therapeutic device to releaseably connect the endoluminal therapeutic device to the elongated pusher member. The body of shape memory material can also be bonded to both the pusher member and the endoluminal device, with the tubular collar being scored to break when the tubular collar changes from the stressed configuration to the recovered configuration. A collet can also be mounted to the pusher member and disposed within.
摘要翻译：用于在体腔内递送腔内装置的腔内装置递送系统和方法使用呈管状套环形式的形状记忆材料，以在输送到期望位置期间接合腔内装置。腔内装置通过将管状颈环围绕腔内装置的一部分或通过粘合剂粘合而机械地接合在管状颈部内部。管状环可围绕内腔装置的茎的圆形部分卷曲。一旦腔内装置通过体腔流动到期望的位置，则通过将热量施加到形状记忆材料的管状环上而与输送系统分离。当管状套管已经被加热到足够的温度时，它将转变到橡胶状态并且长度收缩，从而完全退回到光纤上，导致光纤的远端接合腔内装置并将其移开从管状领。也可以在腔内治疗装置的茎部处使用互锁组件以将腔内治疗装置可释放地连接到细长的推动器构件。形状记忆材料的主体还可以结合到推动器构件和腔内装置上，当管状套环从应力构型改变到恢复构型时，管状环被刻痕以破裂。夹头也可以安装到推动器构件并且设置在其内。

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