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1. 发明授权

US09279730B2 Device having a membrane structure for detecting thermal radiation, and method for production thereof 有权
标题翻译：具有用于检测热辐射的膜结构的装置及其制造方法
公开(公告)号：US09279730B2
公开(公告)日：2016-03-08
申请号：US12601556
申请日：2008-05-28
申请人： Carsten Giebeler , Matthias Schreiter , Christian Paulus
发明人： Carsten Giebeler , Matthias Schreiter , Christian Paulus
IPC分类号： G01J5/02 , G01J5/34 , G01J5/14 , G01J5/22 , G01J5/04 , G01N21/01 , H01L27/146 , H01L41/09 , G01J5/00 , G01J5/20
CPC分类号： G01J5/34 , G01J5/00 , G01J5/0205 , G01J5/0225 , G01J5/023 , G01J5/04 , G01J5/041 , G01J5/045 , G01J5/14 , G01J5/22 , G01J2005/0077 , G01J2005/204 , G01N2021/0106 , H01L27/14683 , H01L41/0973 , Y10T156/10
摘要： In a device for detecting thermal radiation, at least one membrane is provided on which at least one thermal detector element is mounted for the conversion of the thermal radiation into an electric signal and at least one circuit support for carrying the membrane and for carrying at least one readout circuit for reading out the electrical signal, the detector element and the readout circuit being connected together electrically by an electric contact which passes through the membrane. In addition, a method of producing the device with the following method steps is provided: a) provision of the membrane with the detector element and of at least one electrical through-connection and provision of the circuit support and b) bringing together the membrane and the circuit support in such a manner that the detector element and the readout circuit are connected together electrically by an electrical contact passing through the membrane. Production activity is preferably carried out at wafer level: functionalized silicon substrates are stacked upon one another, firmly bonded to one another and then divided into individual elements. Preferably, the detector elements comprise of pyro-electrical detector elements. The device finds application in motion detectors, presence detectors and in thermal imaging cameras.
摘要翻译：在用于检测热辐射的装置中，提供至少一个膜，其上安装有至少一个热检测器元件，用于将热辐射转换成电信号，以及至少一个用于承载膜的电路支架，一个用于读出电信号的读出电路，检测器元件和读出电路由通过膜的电接点电连接在一起。此外，提供了一种通过以下方法步骤制造该装置的方法：a）提供具有检测器元件的膜和至少一个电气通过连接和提供电路支撑件，以及b）将膜和电路支撑件以检测器元件和读出电路通过穿过膜的电接触电连接在一起的方式。生产活性优选在晶片级进行：功能化的硅衬底相互堆叠，彼此牢固地结合，然后分成单个元件。优选地，检测器元件包括热电检测元件。该设备在运动检测器，存在检测器和热成像相机中可以应用。

2. 发明申请

US20070236224A1 Monolithically Integrated Hybridisation Sensor Assembly and Associated Production Method 有权
标题翻译：一体化杂交传感器组件及相关生产方法
公开(公告)号：US20070236224A1
公开(公告)日：2007-10-11
申请号：US11630964
申请日：2005-06-27
申请人： Marcin Augustyniak , Christian Paulus
发明人： Marcin Augustyniak , Christian Paulus
IPC分类号： G01N27/42
CPC分类号： G01N27/3276
摘要： A monolithically integrated sensor assembly is for detecting molecules that are potentially contained in an analyte. The assembly includes: a substrate; at least one sensor electrode, which is located on or in the substrate and is coated with a sensor-active layer, on which electrochemically active particles are generated in the present of the molecules to be detected, the particles being detected via an electric sensor signal on the sensor electrode(s); at least one additional electrode that is located on or in the substrate; and an operating circuit that is integrated into the substrate for controlling the sensor electrode and the additional electrode(s).
摘要翻译：单片集成传感器组件用于检测潜在地包含在分析物中的分子。组件包括：基底; 至少一个传感器电极，其位于衬底上或衬底中并涂覆有传感器有源层，在待测分子的存在中在其上产生电化学活性粒子，经由电传感器信号在传感器电极上; 位于衬底上或衬底中的至少一个附加电极; 以及集成在基板中用于控制传感器电极和附加电极的操作电路。

3. 发明授权

US07123029B2 Circuit arrangement, electrochemical sensor, sensor arrangement, and method for processing a current signal provided via a sensor electrode 有权
标题翻译：电路布置，电化学传感器，传感器布置和用于处理经由传感器电极提供的电流信号的方法
公开(公告)号：US07123029B2
公开(公告)日：2006-10-17
申请号：US10913706
申请日：2004-08-05
申请人： Alexander Frey , Christian Paulus , Meinrad Schienle , Roland Thewes
发明人： Alexander Frey , Christian Paulus , Meinrad Schienle , Roland Thewes
IPC分类号： G01R27/26 , G01N27/26
CPC分类号： G01N27/3276
摘要： Circuit arrangement having a sensor electrode, a first circuit unit, which is electrically coupled to the sensor electrode, and a second circuit unit, which has a first capacitor. The first circuit unit holds an electrical potential of the sensor electrode in a predetermined first reference range around a predetermined electrical desired potential by coupling the first capacitor and the sensor electrode such that there is a matching of their electrical potentials. If the second circuit unit detects the electrical potential of the first capacitor being outside a second reference range, the second circuit unit brings the first capacitor to a first electrical reference potential.
摘要翻译：具有传感器电极，电耦合到传感器电极的第一电路单元和具有第一电容器的第二电路单元的电路装置。第一电路单元通过将第一电容器和传感器电极耦合使得存在与它们的电位相匹配的方式，将传感器电极的电位保持在预定的电气期望电位周围的预定的第一参考范围内。如果第二电路单元检测到第一电容器的电位在第二参考范围之外，则第二电路单元将第一电容器引入第一电参考电位。

4. 发明申请

US20060057025A1 Sensor arrangement and method for operating a sensor arrangement 失效
标题翻译：用于操作传感器装置的传感器布置和方法
公开(公告)号：US20060057025A1
公开(公告)日：2006-03-16
申请号：US10530882
申请日：2003-10-14
申请人： Bjorn-Oliver Eversmann , Christian Paulus , Roland Thewes
发明人： Bjorn-Oliver Eversmann , Christian Paulus , Roland Thewes
IPC分类号： G01N27/00
CPC分类号： G01N27/4145 , G01N33/48728
摘要： A sensor arrangement and method of operating the sensor arrangement are described. The sensor arrangement has sensor devices formed on or in a substrate and a calibration device for calibrating a respective sensor device. Each sensor device has an electrical signal converter which is a field-effect transistor (FET) having a gate terminal coupled to a sensor element that is coupled to the signal converter, a device that keeps constant the electrical voltage between source and drain terminals of the FET, and a device for detecting the value of the electric current flowing through the signal converter. The sensor element characteristically influences the electrical conductivity of the signal converter on account of a sensor event on the sensor element. The calibration device brings the gate region of the FET to an electrical calibration potential such that the electric current is independent of parameter fluctuations of the FET.
摘要翻译：描述了传感器装置和操作传感器装置的方法。传感器装置具有形成在基板上或基板中的传感器装置和用于校准相应传感器装置的校准装置。每个传感器装置具有电信号转换器，该电信号转换器是具有耦合到耦合到信号转换器的传感器元件的栅极端子的场效应晶体管（FET），保持恒定的源极和漏极端子之间的电压的装置 FET和用于检测流过信号转换器的电流值的装置。传感器元件由于传感器元件上的传感器事件而特征地影响信号转换器的电导率。校准装置使FET的栅极区域达到电校准电位，使得电流与FET的参数波动无关。

5. 发明申请

US20050247559A1 Biosensors array and method for operating a biosensor array 有权
标题翻译：用于操作生物传感器阵列的生物传感器阵列和方法
公开(公告)号：US20050247559A1
公开(公告)日：2005-11-10
申请号：US11019948
申请日：2004-12-21
申请人： Alexander Frey , Franz Hofmann , Birgit Holzapfl , Christian Paulus , Meinrad Schienle , Roland Thewes
发明人： Alexander Frey , Franz Hofmann , Birgit Holzapfl , Christian Paulus , Meinrad Schienle , Roland Thewes
IPC分类号： G01N33/53 , G01N27/02 , G01N27/327 , G01N27/403 , G01N27/416 , G01N33/487 , G01N37/00 , G01N27/26
CPC分类号： G01N27/3276
摘要： A biosensor array having a substrate, a plurality of biosensor zones arranged on the substrate, each of which has a first terminal and a second terminal, at least one drive line and at least one detection line, the at least one drive line being electrically insulated from the at least one detection line. In each case the first terminal of each biosensor zone is coupled to precisely one of the at least one drive line and the second terminal of each biosensor zone is coupled to precisely one of the at least one detection line, and at least one of the at least one drive line and at least one of the at least one detection line is coupled to at least two of the biosensor zones. The biosensor array also has a drive unit for providing an electrical drive signal, a detection unit for detecting an electrical detection signal resulting from the electrical drive signal, and a selection unit that couples the drive unit to the drive line of a biosensor zone to be selected and the detection unit to the detection line of the biosensor zone to be selected, whereby the biosensor zone is selected.
摘要翻译：一种具有衬底的生物传感器阵列，布置在所述衬底上的多个生物传感器区域，每个生物传感器区域具有第一端子和第二端子，至少一条驱动线路和至少一条检测线路，所述至少一条驱动线路电绝缘从所述至少一个检测线。在每种情况下，每个生物传感器区域的第一端子被精确地耦合到至少一条驱动线路中的一条，并且每个生物传感器区域的第二端口精确地耦合到至少一条检测线路中的至少一条，至少一个驱动线和所述至少一个检测线中的至少一个耦合到所述生物传感器区域中的至少两个。生物传感器阵列还具有用于提供电驱动信号的驱动单元，用于检测由电驱动信号产生的电检测信号的检测单元，以及将驱动单元与生物传感器区域的驱动线连接的选择单元，将选择的检测单元和生物传感器区域的检测线进行选择，从而选择生物传感器区域。

6. 发明申请

US20050202582A1 Sensor arrangement with improved spatial and temporal resolution 审中-公开
标题翻译：传感器布置具有改进的空间和时间分辨率
公开(公告)号：US20050202582A1
公开(公告)日：2005-09-15
申请号：US11035765
申请日：2005-01-13
申请人： Bjorn-Oliver Eversmann , Martin Jenkner , Christian Paulus , Guido Stromberg , Thomas Sturm , Annelie Stohr
发明人： Bjorn-Oliver Eversmann , Martin Jenkner , Christian Paulus , Guido Stromberg , Thomas Sturm , Annelie Stohr
IPC分类号： G01N27/26 , G01N27/414 , G01N33/487 , H01L21/00
CPC分类号： G01N33/48728 , G01N33/4836 , H01L21/00
摘要： Sensor arrangement having sensor arrays arranged in crossover regions of row and column lines, each of the sensor arrays having a coupler and a sensor element, which influences current flow between a row and column line through the coupler, an accumulative current flow detector that detects accumulative current flow from individual electric current flows provided by the sensor arrays, and a decoder that determines a sensor element at which a sensor signal is present from the accumulative electric current flows. Accumulative current flows which satisfy a predetermined first criterion can be determined from the detected accumulative current flows, and from the accumulative current flows determined an accumulative current flow can be selected as an accumulative current flow which represents a sensor signal and which satisfies a predetermined second criterion, and the sensor element at which a sensor signal is present can be determined from the selected accumulative current flow.
摘要翻译：传感器布置具有布置在行和列线的交叉区域中的传感器阵列，每个传感器阵列具有耦合器和传感器元件，其影响通过耦合器的行和列线之间的电流;累积电流检测器，其检测累积的由传感器阵列提供的来自各个电流的电流流动，以及确定传感器元件的解码器，在传感器元件处存在来自累积电流的传感器信号。可以根据检测到的累积电流来确定满足预定第一标准的累积电流，并且从积累电流确定可以选择累积电流作为表示传感器信号的累积电流，并且满足预定的第二标准，并且可以根据所选择的累积电流来确定存在传感器信号的传感器元件。

7. 发明申请

US20050194250A1 Sensor arrangement and method for operating a sensor arrangement 有权
标题翻译：用于操作传感器装置的传感器布置和方法
公开(公告)号：US20050194250A1
公开(公告)日：2005-09-08
申请号：US11002736
申请日：2004-12-02
申请人： Alexander Frey , Christian Paulus , Meinrad Schienle , Roland Thewes
发明人： Alexander Frey , Christian Paulus , Meinrad Schienle , Roland Thewes
IPC分类号： C12M1/00 , C12Q1/68 , G01N1/00 , G01N27/02
CPC分类号： C12M1/00 , C12Q1/6837 , G01N1/00 , G01N27/3276 , C12Q2565/607
摘要： Sensor arrangement, set up as an integrated circuit, having a substrate, at least three sensor electrodes arranged on the substrate such that, in an operating state in which an electrically conductive substance is introduced into the sensor arrangement, the sensor electrodes are coupled to one another by means of the electrically conductive substance, capture molecules immobilized on at least a portion of the sensor electrodes, wherein molecules to be detected can hybridize with the capture molecules, a control circuit for applying a first electrical signal to a selected sensor electrode and simultaneously applying a second electrical signal to at least two of the other sensor electrodes, the first electrical signal being a first temporally variable electrical signal and/or the second electrical signal being a second temporally variable electrical signal, a detection device, which is set up such that, in a first operating state, in which a reference liquid is introduced into the sensor arrangement, a reference value of a third temporally variable electrical signal resulting from the first temporally variable electrical signal and/or from the second temporally variable electrical signal is detected at the selected sensor electrode, and in a second operating state, in which an analyte possibly having molecules to be detected is introduced into the sensor arrangement, a sensor value of the third temporally variable electrical signal resulting from the first temporally variable electrical signal and/or from the second temporally variable electrical signal is detected at the selected sensor electrode, and an evaluation circuit, which, on the basis of the reference value and the sensor value, determines whether a hybridization event has taken place at the selected sensor electrode.
摘要翻译：设置为集成电路的传感器布置，具有衬底，布置在衬底上的至少三个传感器电极，使得在将导电物质引入传感器装置的操作状态下，传感器电极耦合到一个另一个通过导电物质捕获固定在传感器电极的至少一部分上的分子，其中待检测的分子可与捕获分子杂交;控制电路，用于将第一电信号施加到所选择的传感器电极，同时将第二电信号施加到至少两个其它传感器电极，所述第一电信号是第一时间可变电信号和/或所述第二电信号是第二时间可变电信号，所述检测装置被设置为在第一操作状态下，将参考液体引入到传感器中在所选择的传感器电极处检测由第一时间可变电信号和/或来自第二时间可变电信号产生的第三时间可变电信号的参考值，并且在第二操作状态中，分析物可能将要检测的分子引入传感器装置中，在所选择的传感器电极处检测由第一时间可变电信号和/或来自第二时间可变电信号产生的第三时间可变电信号的传感器值，评估电路，其基于参考值和传感器值确定在所选择的传感器电极处是否发生杂交事件。

8. 发明申请

US20050136423A1 Method and biosensors for detecting macromolecular biopolymers 有权
标题翻译：用于检测大分子生物聚合物的方法和生物传感器
公开(公告)号：US20050136423A1
公开(公告)日：2005-06-23
申请号：US10841413
申请日：2004-05-07
申请人： Christian Paulus , Petra Schindler-Bauer
发明人： Christian Paulus , Petra Schindler-Bauer
IPC分类号： C12M1/34 , C12Q1/68 , G01N33/543
CPC分类号： G01N33/5438
摘要： Method for detecting macromolecular biopolymers using a unit for immobilizing macromolecular biopolymers, in which the unit is provided with first molecules serving as capture molecules. The method includes the steps of bringing a sample into contact with the unit, it being possible for the sample to contain the macromolecular biopolymers, and the macromolecular biopolymers or the first molecules having a marking which is used to generate a detectable signal, binding macromolecular biopolymers contained in the sample to the capture molecules, thereby forming complexes comprising capture molecules and macromolecular biopolymers, exciting the emission of a signal by means of the marking, detecting the signal emitted by means of the marking, separating the complexes comprising capture molecules and macromolecular biopolymers, thereby altering the intensity of the emitted signal, and detecting the separation of the complexes comprising capture molecules and macromolecular biopolymers by means of the change in the intensity of the signal.
摘要翻译：使用用于固定大分子生物聚合物的单元检测大分子生物聚合物的方法，其中该单元具有用作捕获分子的第一分子。该方法包括使样品与单元接触的步骤，样品可以含有大分子生物聚合物，大分子生物聚合物或具有用于产生可检测信号的标记的第一分子，结合大分子生物聚合物包含在捕获分子中的样品，从而形成包含捕获分子和大分子生物聚合物的复合物，通过标记激发信号的发射，检测通过标记发射的信号，分离包含捕获分子和大分子生物聚合物的复合物从而改变发射信号的强度，并通过信号强度的变化来检测包含捕获分子和大分子生物聚合物的络合物的分离。

9. 发明授权

US06819147B2 Current sample-and-hold-circuit, a/d converter and a method for operating a current sample-and-hold circuit 有权
标题翻译：电流采样保持电路，a / d转换器和用于操作电流采样保持电路的方法
公开(公告)号：US06819147B2
公开(公告)日：2004-11-16
申请号：US10297496
申请日：2003-04-07
申请人： Christian Paulus
发明人： Christian Paulus
IPC分类号： G11C2702
CPC分类号： G11C27/028
摘要： The invention relates to a current sample-and-hold circuit comprising several sub-circuits, in which a current signal is stored. At least one of said sub-circuits contains a switch. The inventive current hold-and-sample circuit is characterized in that each of the sub-circuits contains a linear resistor, which is connected in such a way that the current signal generates a voltage drop across the resistor, that each of the sub-circuits contains at least one inverting control amplifier, which sets an initial current of the circuit in a hold operational mode, thus inducing a voltage drop across the resistor, said voltage drop being substantially as great as the voltage drop across the resistor before the hold operational mode.
摘要翻译：本发明涉及一种包含几个子电路的电流采样和保持电路，其中存储有电流信号。所述子电路中的至少一个包含开关。本发明的电流保持和采样电路的特征在于，每个子电路包含线性电阻器，其以电流信号在电阻器两端产生电压降的方式连接，每个子电路包含至少一个反相控制放大器，其将电路的初始电流设置为保持操作模式，从而导致电阻器两端的电压降，所述电压降基本上与保持操作模式之前的电阻器两端的电压降一样大。

10. 发明授权

US06812880B2 Analog-to-digital converter and method for converting an analog signal into a digital signal 有权
标题翻译：用于将模拟信号转换为数字信号的模数转换器和方法
公开(公告)号：US06812880B2
公开(公告)日：2004-11-02
申请号：US10433711
申请日：2003-09-29
申请人： Christian Paulus
发明人： Christian Paulus
IPC分类号： H03M134
CPC分类号： H03M1/0643 , H03M1/365
摘要： The invention relates to an analog-to-digital converter (301), comprising several comparators (303) and a reference network, said reference network having several reference elements (302). At least one input (304) of at least one comparator (303) is connected between the individual reference elements (302) of the reference network in the analog-to-digital converter (301), respectively. A digital evaluation circuit (311) with which the statistical evaluation of the output signals generated by the comparators (303) can be carried out is linked to the outputs (309) of the comparators of the analog-to-digital converter (301). The invention also relates to a corresponding method for converting an analog signal (Ua) into a digital signal (D).
摘要翻译：本发明涉及一种包括多个比较器（303）和参考网络的模数转换器（301），所述参考网络具有几个参考元件（302）。至少一个比较器（303）的至少一个输入（304）分别连接在模数转换器（301）中的参考网络的各个参考元件（302）之间。可以执行由比较器（303）产生的输出信号的统计评估的数字评估电路（311）与模数转换器（301）的比较器的输出（309）相关联。本发明还涉及将模拟信号（Ua）转换为数字信号（D）的相应方法。

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