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    • 1. 发明申请
    • Method of Separating Cells and Separation Apparatus
    • 分离细胞和分离装置的方法
    • US20130005038A1
    • 2013-01-03
    • US13583746
    • 2011-03-09
    • Chikashi Nakamura
    • Chikashi Nakamura
    • C12N5/02C12M1/00
    • C12M47/04
    • A method and apparatus for discriminating and separating only specific cells in cell samples is provided. The cell separation operation includes inserting a needle-shaped body, on which a substance that selectively binds to a marker substance within each target cell has been immobilized, into each of the cell samples on a substrate, thereby causing the marker substance within each target cell in the cell samples to bind to the needle-shaped body through the substance that selectively binds to the marker substance, and then, putting up the needle-shaped body. The binding force between the needle-shaped body and each target cell when the marker substance within each target cell has bound to the needle-shaped body is made greater than an adhesion force of each of the cell samples to the substrate, so that only target cells each containing the marker substance are pulled up and separated from the substrate.
    • 提供了用于区分和分离细胞样品中特定细胞的方法和装置。 细胞分离操作包括将在其上固定有选择性结合每个靶细胞内的标记物质的物质的针状体插入到基底上的每个细胞样品中,从而在每个靶细胞内引起标记物质 在细胞样品中通过选择性地结合标记物质的物质结合针状体,然后放置针状体。 当每个靶细胞内的标记物质与针状体结合时,针状体与每个靶细胞之间的结合力大于每个细胞样品对基底的粘附力,使得仅靶 将每个含有标记物质的细胞从基质中拉起并分离。
    • 3. 发明授权
    • Image reading device and focus adjustment method thereof
    • 图像读取装置及其焦点调整方法
    • US06608705B1
    • 2003-08-19
    • US09331399
    • 1999-06-21
    • Toshiaki OshimaChikashi Nakamura
    • Toshiaki OshimaChikashi Nakamura
    • H04N104
    • H04N1/00013H04N1/00031H04N1/00063H04N1/00082H04N1/02409H04N1/03H04N1/1013H04N1/193
    • There are provided an image reading apparatus and a focus adjusting method thereof in which focusing can be accurately conducted by a simple moving mechanism. A condenser lens and line sensor can be moved being integrated with each other. When output values obtained when a document on AF line is read by a line sensor are represented by LS1, LS2, LS3, . . . , and when a broken line graph is considered on which the horizontal axis represents a reading position in the horizontal scanning direction and the vertical axis represents an intensity of an output signal, it is judged that the larger the total distance LM1+LM2+ . . . of the broken lines is, the more accurately the image is in focus. A square root of the sum of the square of a distance between the adjacent reading positions and the square of a difference of intensities of the signals which have been read, is calculated, and it is judged that the larger the sum is, the more accurately the focus is adjusted.
    • 提供了一种图像读取装置和焦点调节方法,其中可以通过简单的移动机构精确地进行聚焦。 可以使聚光透镜和线传感器相互移动。 当通过线传感器读取AF线上的文档时获得的输出值由LS1,LS2,LS3表示。 。 。 ,并且当考虑横线表示水平扫描方向上的读取位置并且垂直轴表示输出信号的强度的虚线图时,判断总距离LM1 + LM2 +越大。 。 。 的虚线是,图像的焦点越准确。 计算相邻读取位置之间的距离的平方和所读取的信号的强度差的平方之和的平方根,并且判断为和越大越准确 重点调整。
    • 5. 发明申请
    • LIQUID SUPPLYING APPARATUS AND LIQUID EJECTING APPARATUS
    • 液体供应装置和液体喷射装置
    • US20100245465A1
    • 2010-09-30
    • US12729508
    • 2010-03-23
    • Chikashi NAKAMURASeiya SATO
    • Chikashi NAKAMURASeiya SATO
    • B41J2/165
    • B41J2/1652B41J2/16526B41J2/16532B41J2/175B41J2/17596
    • A liquid ejecting apparatus includes a liquid ejecting head and a cleaning device. The liquid ejecting head has a nozzle formation surface and nozzles formed therethrough. The cleaning device applies a suction force to the inside of the liquid ejecting head through the nozzles to suck the liquid out of the liquid ejecting head for forcible discharging of the liquid. A liquid supplying apparatus includes a liquid supplying passage through which the liquid is supplied from a liquid supplying source at an upstream side, toward the liquid ejecting head at a downstream side. A pump is driven for suction and discharging operations. The pump includes a pump chamber and a displacement member. The displacement member is displaced between two or more positions that include a close position for closing an outlet port through which the liquid flows out of the pump chamber to the downstream side.
    • 液体喷射装置包括液体喷射头和清洁装置。 液体喷射头具有喷嘴形成表面和通过其形成的喷嘴。 清洁装置通过喷嘴向液体喷射头的内部施加吸力,以将液体从液体喷射头吸出以强制排出液体。 液体供应装置包括液体供应通道,液体从上游侧的液体供给源供给到液体供给通道,在下游侧朝向液体喷射头供给。 驱动泵进行抽吸和排放操作。 泵包括泵室和排量构件。 位移构件在两个或多个位置之间移动,该位置包括用于关闭液体从泵室流出到下游侧的出口的关闭位置。
    • 6. 发明授权
    • Method of separating cells and separation apparatus
    • 分离细胞和分离装置的方法
    • US09175255B2
    • 2015-11-03
    • US13583746
    • 2011-03-09
    • Chikashi Nakamura
    • Chikashi Nakamura
    • C12M1/00C12M3/00
    • C12M47/04
    • A method and apparatus for discriminating and separating only specific cells in cell samples is provided. The cell separation operation includes inserting a needle-shaped body, on which a substance that selectively binds to a marker substance within each target cell has been immobilized, into each of the cell samples on a substrate, thereby causing the marker substance within each target cell in the cell samples to bind to the needle-shaped body through the substance that selectively binds to the marker substance, and then, pulling up the needle-shaped body. The binding force between the needle-shaped body and each target cell when the marker substance within each target cell has bound to the needle-shaped body is made greater than an adhesion force of each of the cell samples to the substrate, so that only target cells each containing the marker substance are pulled up and separated from the substrate.
    • 提供了用于区分和分离细胞样品中特定细胞的方法和装置。 细胞分离操作包括将在其上固定有选择性结合每个靶细胞内的标记物质的物质的针状体插入到基底上的每个细胞样品中,从而在每个靶细胞内引起标记物质 在细胞样品中通过选择性结合标记物质的物质结合针状体,然后拉起针状体。 当每个靶细胞内的标记物质与针状体结合时,针状体与每个靶细胞之间的结合力大于每个细胞样品对基底的粘附力,使得仅靶 将每个含有标记物质的细胞从基质中拉起并分离。