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1. 发明授权

US07825819B2 Remote shock sensing and notification system 有权
标题翻译：远程震动感应通知系统
公开(公告)号：US07825819B2
公开(公告)日：2010-11-02
申请号：US12268657
申请日：2008-11-11
申请人： Govindarajan Muralidharan , Charles L. Britton , James Pearce , Usha Jagadish , Vinod K. Sikka
发明人： Govindarajan Muralidharan , Charles L. Britton , James Pearce , Usha Jagadish , Vinod K. Sikka
IPC分类号： G08B21/00
CPC分类号： G08B13/1663 , G08B31/00
摘要： A low-power shock sensing system includes at least one shock sensor physically coupled to a chemical storage tank to be monitored for impacts, and an RF transmitter which is in a low-power idle state in the absence of a triggering signal. The system includes interface circuitry including or activated by the shock sensor, wherein an output of the interface circuitry is coupled to an input of the RF transmitter. The interface circuitry triggers the RF transmitter with the triggering signal to transmit an alarm message to at least one remote location when the sensor senses a shock greater than a predetermined threshold. In one embodiment the shock sensor is a shock switch which provides an open and a closed state, the open state being a low power idle state.
摘要翻译：低功率冲击感测系统包括至少一个物理耦合到要监控冲击的化学品储罐的冲击传感器，以及在没有触发信号的情况下处于低功率空闲状态的RF发射器。该系统包括由冲击传感器包括或激活的接口电路，其中接口电路的输出耦合到RF发射器的输入端。当传感器感测到大于预定阈值的冲击时，接口电路触发具有触发信号的RF发射器，以向至少一个远程位置发送警报消息。在一个实施例中，冲击传感器是提供打开和关闭状态的冲击开关，打开状态是低功率空闲状态。

2. 发明申请

US20100072380A1 SPACE CHARGE DOSIMETERS FOR EXTREMELY LOW POWER MEASUREMENTS OF RADIATION IN SHIPPING CONTAINERS 有权
标题翻译：用于运输集装箱辐射的极低功率测量的空间充电量计
公开(公告)号：US20100072380A1
公开(公告)日：2010-03-25
申请号：US12406680
申请日：2009-03-18
申请人： Charles L. Britton, JR. , Mark A. Buckner , Gregory R. Hanson , William L. Bryan
发明人： Charles L. Britton, JR. , Mark A. Buckner , Gregory R. Hanson , William L. Bryan
IPC分类号： G01T1/02
CPC分类号： G06Q10/08 , G08B13/2462 , G08B21/12 , H01L2924/0002 , H01L2924/00
摘要： Methods and apparatus are described for space charge dosimeters for extremely low power measurements of radiation in shipping containers. A method includes insitu polling a suite of passive integrating ionizing radiation sensors including reading-out dosimetric data from a first passive integrating ionizing radiation sensor and a second passive integrating ionizing radiation sensor, where the first passive integrating ionizing radiation sensor and the second passive integrating ionizing radiation sensor remain situated where the dosimetric data was integrated while reading-out. Another method includes arranging a plurality of ionizing radiation sensors in a spatially dispersed array; determining a relative position of each of the plurality of ionizing radiation sensors to define a volume of interest; collecting ionizing radiation data from at least a subset of the plurality of ionizing radiation sensors; and triggering an alarm condition when a dose level of an ionizing radiation source is calculated to exceed a threshold.
摘要翻译：描述了用于运输容器中辐射极低功率测量的空间电荷剂量计的方法和装置。一种方法包括自动轮询一套无源积分电离辐射传感器，包括来自第一无源积分电离辐射传感器和第二无源积分电离辐射传感器的读出剂量学数据，其中第一无源积分电离辐射传感器和第二被动积分电离辐射传感器仍然位于读数时集成剂量测量数据的位置。另一种方法包括在空间上分散的阵列中布置多个电离辐射传感器; 确定所述多个电离辐射传感器中的每一个的相对位置以定义感兴趣的体积; 从所述多个电离辐射传感器的至少一个子集收集电离辐射数据; 并且当计算电离辐射源的剂量水平超过阈值时触发警报状况。

3. 发明授权

US4866400A Automatic pole-zero adjustment circuit for an ionizing radiation spectroscopy system 失效
标题翻译：用于电离辐射光谱系统的自动极零调整电路
公开(公告)号：US4866400A
公开(公告)日：1989-09-12
申请号：US144119
申请日：1988-01-15
申请人： Charles L. Britton, Jr. , Thomas H. Becker , Michael O. Bedwell
发明人： Charles L. Britton, Jr. , Thomas H. Becker , Michael O. Bedwell
IPC分类号： G01N23/221 , G01R17/06
CPC分类号： G01R17/06
摘要： An automatic pole-zero adjustment circuit is provided for an ionizing radiation spectroscopy system which comprises a pole-zero network circuit, coupled to the system and having an electrical chracteristic which varies as a function of an input control signal, for permitting pole-zero adjustment of the system; a sampling circuit coupled to the system, for sampling a segment of the trailing edge of random pulses passing through the system; and a control signal circuit coupled to the sampling circuit, for generating the input control signal as a function of the sampling to permit cancellation by the pole-zero network circuit of undershoot in the system. The pole-zero network circuit may include a real pole in the signal path of the network circuit set coincident with the real pole of a high pass filter in the system itself. The control signal provided to the pole-zero network circuit is digitized.

4. 发明授权

US07936270B2 Space charge dosimeters for extremely low power measurements of radiation in shipping containers 有权
标题翻译：运输容器中辐射极低功率测量的空间电荷剂量计
公开(公告)号：US07936270B2
公开(公告)日：2011-05-03
申请号：US12406680
申请日：2009-03-18
申请人： Charles L. Britton, Jr. , Mark A. Buckner , Gregory R. Hanson , William L. Bryan
发明人： Charles L. Britton, Jr. , Mark A. Buckner , Gregory R. Hanson , William L. Bryan
IPC分类号： G08B13/14 , H01L29/76 , H01L23/28 , G01T1/24
CPC分类号： G06Q10/08 , G08B13/2462 , G08B21/12 , H01L2924/0002 , H01L2924/00
摘要： Methods and apparatus are described for space charge dosimeters for extremely low power measurements of radiation in shipping containers. A method includes insitu polling a suite of passive integrating ionizing radiation sensors including reading-out dosimetric data from a first passive integrating ionizing radiation sensor and a second passive integrating ionizing radiation sensor, where the first passive integrating ionizing radiation sensor and the second passive integrating ionizing radiation sensor remain situated where the dosimetric data was integrated while reading-out. Another method includes arranging a plurality of ionizing radiation sensors in a spatially dispersed array; determining a relative position of each of the plurality of ionizing radiation sensors to define a volume of interest; collecting ionizing radiation data from at least a subset of the plurality of ionizing radiation sensors; and triggering an alarm condition when a dose level of an ionizing radiation source is calculated to exceed a threshold.
摘要翻译：描述了用于运输容器中辐射极低功率测量的空间电荷剂量计的方法和装置。一种方法包括自动轮询一套无源积分电离辐射传感器，包括来自第一无源积分电离辐射传感器和第二无源积分电离辐射传感器的读出剂量学数据，其中第一无源积分电离辐射传感器和第二被动积分电离辐射传感器仍然位于读数时集成剂量测量数据的位置。另一种方法包括在空间上分散的阵列中布置多个电离辐射传感器; 确定所述多个电离辐射传感器中的每一个的相对位置以限定感兴趣的体积; 从所述多个电离辐射传感器的至少一个子集收集电离辐射数据; 并且当计算电离辐射源的剂量水平超过阈值时触发警报状况。

5. 发明申请

US20090240271A1 RETINAL INSTRUMENT 有权
标题翻译：离子仪器
公开(公告)号：US20090240271A1
公开(公告)日：2009-09-24
申请号：US12052992
申请日：2008-03-21
申请人： Charles L. Britton , Brian R. D'Urso , Edward Chaum , John T. Simpson , Justin S. Baba , M. Nance Ericson , Robert J. Warmack
发明人： Charles L. Britton , Brian R. D'Urso , Edward Chaum , John T. Simpson , Justin S. Baba , M. Nance Ericson , Robert J. Warmack
IPC分类号： A61F9/00
CPC分类号： A61F9/00736 , A61B17/205 , A61F9/007 , A61F9/00727
摘要： In one embodiment, the present invention provides a method of removing scar tissue from an eye that includes inserting a device including an array of micro-rods into an eye, wherein at least one glass micro-rod of the array of glass micro-rods includes a sharp feature; contacting a scar tissue with the array of micro-rods; and removing the array of micro-rods and the scar tissue from the eye. In another embodiment, the present invention provides a medical device for engaging a tissue including and an array of glass micro-rods, wherein at least one glass micro-rod of the array of glass micro-rods includes a sharp feature opposite a base of the array of glass micro-rods that is connected to the cannula, wherein the sharp feature of the at least one micro-rod is angled from a plane that is normal to a face of the base of the array of glass micro-rods.
摘要翻译：在一个实施方案中，本发明提供了一种从眼睛去除疤痕组织的方法，包括将包括微棒阵列的装置插入到眼睛中，其中玻璃微棒阵列的至少一个玻璃微棒包括一个尖锐的特征; 使疤痕组织与微杆阵列接触; 并从眼睛中移除微杆阵列和瘢痕组织。在另一个实施方案中，本发明提供了一种用于接合包括玻璃微棒和玻璃微棒的阵列的组织的医疗装置，其中所述玻璃微棒阵列的至少一个玻璃微棒包括与所述玻璃微棒的基底相对的尖锐特征连接到插管的玻璃微杆的阵列，其中所述至少一个微杆的尖锐特征从与所述玻璃微棒阵列的基部的面垂直的平面成角度。

6. 发明授权

US5590104A Method of pedestal and common-mode noise correction for switched-capacitor analog memories 失效
标题翻译：开关电容模拟存储器的基座和共模噪声校正方法
公开(公告)号：US5590104A
公开(公告)日：1996-12-31
申请号：US316193
申请日：1994-09-30
申请人： Charles L. Britton
发明人： Charles L. Britton
IPC分类号： G11C27/00
CPC分类号： G11C27/00
摘要： A method and apparatus for correcting common-mode noise and pedestal noise in a multichannel array of switched-capacitor analog memories wherein each analog memory is connected to an associated analog-to-digital converter. The apparatus comprises a single differential element in two different embodiments. In a first embodiment, the differential element is a reference analog memory connected to a buffer. In the second embodiment, the differential element is a reference analog memory connected to a reference analog-to-digital connected to an array of digital summing circuits.
摘要翻译：一种用于校正开关电容器模拟存储器的多通道阵列中的共模噪声和基座噪声的方法和装置，其中每个模拟存储器连接到相关联的模拟 - 数字转换器。该装置包括两个不同实施例中的单个差分元件。在第一实施例中，差分元件是连接到缓冲器的参考模拟存储器。在第二实施例中，差分元件是连接到与数字求和电路阵列连接的参考模拟数字量的参考模拟存储器。

7. 发明授权

US07525431B2 Space charge dosimeters for extremely low power measurements of radiation in shipping containers 失效
标题翻译：运输容器中辐射极低功率测量的空间电荷剂量计
公开(公告)号：US07525431B2
公开(公告)日：2009-04-28
申请号：US10840553
申请日：2004-05-06
申请人： Charles L. Britton, Jr. , Mark A. Buckner , Gregory R. Hanson , William L. Bryan
发明人： Charles L. Britton, Jr. , Mark A. Buckner , Gregory R. Hanson , William L. Bryan
IPC分类号： G08B13/14
CPC分类号： G06Q10/08 , G08B13/2462 , G08B21/12 , H01L2924/0002 , H01L2924/00
摘要： Methods and apparatus are described for space charge dosimeters for extremely low power measurements of radiation in shipping containers. A method includes insitu polling a suite of passive integrating ionizing radiation sensors including reading-out dosimetric data from a first passive integrating ionizing radiation sensor and a second passive integrating ionizing radiation sensor, where the first passive integrating ionizing radiation sensor and the second passive integrating ionizing radiation sensor remain situated where the dosimetric data was integrated while reading-out. Another method includes arranging a plurality of ionizing radiation sensors in a spatially dispersed array; determining a relative position of each of the plurality of ionizing radiation sensors to define a volume of interest; collecting ionizing radiation data from at least a subset of the plurality of ionizing radiation sensors; and triggering an alarm condition when a dose level of an ionizing radiation source is calculated to exceed a threshold.
摘要翻译：描述了用于运输容器中辐射极低功率测量的空间电荷剂量计的方法和装置。一种方法包括自动轮询一套无源积分电离辐射传感器，包括来自第一无源积分电离辐射传感器和第二无源积分电离辐射传感器的读出剂量学数据，其中第一无源积分电离辐射传感器和第二被动积分电离辐射传感器仍然位于读数时集成剂量测量数据的位置。另一种方法包括在空间上分散的阵列中布置多个电离辐射传感器; 确定所述多个电离辐射传感器中的每一个的相对位置以限定感兴趣的体积; 从所述多个电离辐射传感器的至少一个子集收集电离辐射数据; 并且当计算电离辐射源的剂量水平超过阈值时触发警报状况。

8. 发明授权

US06399951B1 Simultaneous CT and SPECT tomography using CZT detectors 失效
标题翻译：使用CZT检测器的同时CT和SPECT断层扫描
公开(公告)号：US06399951B1
公开(公告)日：2002-06-04
申请号：US09496880
申请日：2000-02-02
申请人： Michael J. Paulus , Hamed Sari-Sarraf , Michael L. Simpson , Charles L. Britton, Jr.
发明人： Michael J. Paulus , Hamed Sari-Sarraf , Michael L. Simpson , Charles L. Britton, Jr.
IPC分类号： G01T1161
CPC分类号： A61B6/482 , A61B6/032 , A61B6/037 , A61B6/4035 , A61B6/4092 , A61B6/4241 , A61B6/4417 , A61B6/508 , A61B6/5235 , G01T1/1648
摘要： A method for simultaneous transmission x-ray computed tomography (CT) and single photon emission tomography (SPECT) comprises the steps of: injecting a subject with a tracer compound tagged with a &ggr;-ray emitting nuclide; directing an x-ray source toward the subject; rotating the x-ray source around the subject; emitting x-rays during the rotating step; rotating a cadmium zinc telluride (CZT) two-sided detector on an opposite side of the subject from the source; simultaneously detecting the position and energy of each pulsed x-ray and each emitted &ggr;-ray captured by the CZT detector; recording data for each position and each energy of each the captured x-ray and &ggr;-ray; and, creating CT and SPECT images from the recorded data. The transmitted energy levels of the x-rays lower are biased lower than energy levels of the &ggr;-rays. The x-ray source is operated in a continuous mode. The method can be implemented at ambient temperatures.
摘要翻译：用于同时透射x射线计算机断层摄影（CT）和单光子发射断层摄影（SPECT）的方法包括以下步骤：用标有伽马射线放射核素的示踪剂化合物注射受试者; 将x射线源引导到受试者; 围绕主体旋转x射线源; 在旋转步骤期间发射X射线; 在来自对象的另一侧旋转碲化锌碲化镉（CZT）双面检测器; 同时检测每个脉冲X射线的位置和能量以及由CZT检测器捕获的每个发射的γ射线; 记录每个位置的数据和每个捕获的X射线和γ射线的每个能量; 并从记录的数据创建CT和SPECT图像。 x射线的透射能级低于伽马射线的能级。 x射线源以连续模式运行。该方法可以在环境温度下实现。

9. 发明授权

US5986272A Real-time method and apparatus for measuring the temperature of a fluorescing phosphor 有权
标题翻译：用于测量荧光荧光粉温度的实时方法和装置
公开(公告)号：US5986272A
公开(公告)日：1999-11-16
申请号：US293916
申请日：1999-04-19
申请人： Charles L. Britton, Jr. , David L. Beshears , Marc L. Simpson , Michael R. Cates , Steve W. Allison
发明人： Charles L. Britton, Jr. , David L. Beshears , Marc L. Simpson , Michael R. Cates , Steve W. Allison
IPC分类号： G01K11/20 , G01K11/00
CPC分类号： G01K11/20
摘要： A method for determining the temperature of a fluorescing phosphor is provided, together with an apparatus for performing the method. The apparatus includes a photodetector for detecting light emitted by a phosphor irradiated with an excitation pulse and for converting the detected light into an electrical signal. The apparatus further includes a differentiator for differentiating the electrical signal and a zero-crossing discrimination circuit that outputs a pulse signal having a pulse width corresponding to the time period between the start of the excitation pulse and the time when the differentiated electrical signal reaches zero. The width of the output pulse signal is proportional to the decay-time constant of the phosphor.
摘要翻译：提供了用于确定荧光荧光体的温度的方法以及用于执行该方法的装置。该装置包括用于检测由激发脉冲照射的荧光体发射的光并用于将检测到的光转换成电信号的光电检测器。该装置还包括用于区分电信号的微分器和输出具有与激励脉冲开始与微分电信号达到零时间之间的时间间隔相对应的脉冲宽度的脉冲信号的过零鉴别电路。输出脉冲信号的宽度与荧光体的衰减时间常数成比例。

10. 发明授权

US08591481B2 Microfabricated instruments and methods to treat recurrent corneal erosion 有权
标题翻译：微量手术和治疗复发性角膜糜烂的方法
公开(公告)号：US08591481B2
公开(公告)日：2013-11-26
申请号：US12052971
申请日：2008-03-21
申请人： Charles L. Britton , Brian R. D'Urso , Edward Chaum , John T. Simpson , Justin S. Baba , M. Nance Ericson , Robert J. Warmack
发明人： Charles L. Britton , Brian R. D'Urso , Edward Chaum , John T. Simpson , Justin S. Baba , M. Nance Ericson , Robert J. Warmack
IPC分类号： A61M5/158
CPC分类号： A61F9/007 , A61B2017/320004 , A61F9/0017
摘要： In one embodiment, the present invention provides a device and method for treating recurrent corneal erosion. In one embodiment, the method includes the steps of contacting an epithelium layer of a cornea with an array of glass micro-rods including a plurality of sharp features having a length that penetrates a Bowman's layer of the eye, wherein the plurality of sharp features of the array of glass micro-rods produces a plurality of punctures in the Bowman's layer of the eye that are of micro-scale or less. In another embodiment, the present invention provides a method and device for drug delivery. In one embodiment, the device includes an array of glass micro-rods, wherein at least one glass micro-rod of the array of glass micro-rods includes a sharp feature opposite a base of the array of glass micro-rods, wherein the sharp feature includes a treated surface for delivering a chemical compound to the eye.
摘要翻译：在一个实施方案中，本发明提供了用于治疗复发性角膜侵蚀的装置和方法。在一个实施例中，该方法包括以下步骤：使角膜的上皮层与玻璃微杆阵列接触，所述玻璃微杆包括具有穿透眼睛Bowman层的长度的多个尖锐特征，其中多个尖锐特征玻璃微棒的阵列在眼睛的Bowman层中产生微量级或更小的多个穿刺。在另一个实施方案中，本发明提供用于药物递送的方法和装置。在一个实施例中，该装置包括玻璃微棒阵列，其中玻璃微棒阵列的至少一个玻璃微棒包括与玻璃微棒阵列相对的尖锐特征，其中尖锐特征包括用于将化学化合物递送至眼睛的处理表面。

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