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1. 发明授权

US09421356B2 Transdermal methods and systems for the delivery of corticosteroid compounds 有权
标题翻译：用于输送皮质类固醇化合物的透皮方法和系统
公开(公告)号：US09421356B2
公开(公告)日：2016-08-23
申请号：US12199051
申请日：2008-08-27
申请人： Carter R. Anderson , Russell L. Morris , Robert Cohen , William V. Fowler
发明人： Carter R. Anderson , Russell L. Morris , Robert Cohen , William V. Fowler
IPC分类号： A61N1/04 , A61K9/00
CPC分类号： A61N1/0448 , A61K9/0009 , A61N1/044
摘要： An integrated iontophoresis skin-worn patch and method for delivering a therapeutically effective amount of a corticosteroid drug compound in a systemically-safe and skin-safe manner for site-specific treatment of inflammation pain is disclosed.
摘要翻译：公开了一种用于以系统安全和皮肤安全的方式递送治疗有效量的皮质类固醇药物化合物的综合离子电渗皮肤磨损贴片和方法，用于炎症疼痛的特异性治疗。

2. 发明授权

US08295924B2 Transdermal systems for the delivery of ionic agents directly to open wounds and surgically repaired incisions 有权
标题翻译：用于将离子剂直接递送至开放性伤口和手术修复的切口的透皮系统
公开(公告)号：US08295924B2
公开(公告)日：2012-10-23
申请号：US13009999
申请日：2011-01-20
申请人： Carter R. Anderson , Russell L. Morris , Robert Cohen
发明人： Carter R. Anderson , Russell L. Morris , Robert Cohen
IPC分类号： A61N1/30 , A61M31/00 , A61F13/00
CPC分类号： A61N1/0448
摘要： A transdermal system for the delivery of an anesthetic or other active therapeutic agent directly to a selected site of injured skin tissue by iontophoresis is disclosed, which utilizes a transdermal skin-worn patch including a donor electrode chamber containing a donor electrode and an amount of an active agent in a form suitable for transdermal delivery in electrical communication with the donor electrode and a return electrode. The patch also contains a source of electric current connected in a circuit with the donor and return electrode, a current regulating device is optionally provided in the circuit for controlling the electrical output of the patch and at least the donor electrode chamber includes a provision for absorbing a quantity of fluid associated with weepage from adjacent injured skin tissue.
摘要翻译：公开了一种用于通过离子电渗法将麻醉剂或其它活性治疗剂直接递送至受损皮肤组织的选定部位的透皮系统，其利用透皮的皮肤佩戴的贴片，其包括供体电极室，其包含施主电极和活性剂，其形式适合于与供体电极和返回电极电连通的透皮递送。贴片还包含与供体和返回电极在电路中连接的电流源，电路中可选地提供电流调节装置，用于控制贴片的电输出，并且至少供体电极室包括用于吸收与来自相邻受伤皮肤组织的渗漏相关的一定量的流体。

3. 发明申请

US20110092926A1 ABUSE POTENTIAL REDUCTION IN ABUSABLE SUBSTANCE DOSAGE FORM 有权
标题翻译：滥用可吸收物质剂量形式的潜在减少
公开(公告)号：US20110092926A1
公开(公告)日：2011-04-21
申请号：US12976610
申请日：2010-12-22
申请人： Carter R. Anderson , Russell L. Morris
发明人： Carter R. Anderson , Russell L. Morris
IPC分类号： A61M35/00 , A61B19/02
CPC分类号： A62D3/33 , A61J1/00 , A61J1/14 , A61K9/7084 , A61K31/445 , A62D3/00 , A62D2101/26 , B09B3/0075 , B09B2220/14 , B65D25/14
摘要： The potential for substance abuse involving residual amounts of abusable substances remaining in used skin-worn patches is reduced by the provision of a system and method for combining the abusable substance with a separate anti-abuse substance agent as part of a removal or disposal procedure.
摘要翻译：通过提供将可滥用物质与单独的抗滥用物质试剂相结合的系统和方法作为去除或处理程序的一部分，减少了残留在使用过的皮肤磨损块中的残留量的可滥用物质的潜在的药物滥用。

4. 发明授权

US07867511B2 Abuse potential reduction in abusable substance dosage form 有权
标题翻译：滥用潜在的可吸入物质剂量减少
公开(公告)号：US07867511B2
公开(公告)日：2011-01-11
申请号：US10763628
申请日：2004-01-23
申请人： Carter R. Anderson , Russell L. Morris
发明人： Carter R. Anderson , Russell L. Morris
IPC分类号： A61K9/70 , A61F13/00
CPC分类号： A62D3/33 , A61J1/00 , A61J1/14 , A61K9/7084 , A61K31/445 , A62D3/00 , A62D2101/26 , B09B3/0075 , B09B2220/14 , B65D25/14
摘要： The potential for substance abuse involving residual amounts of abusable substances remaining in used skin-worn patches is reduced by the provision of a system and method for combining the abusable substance with a separate anti-abuse substance agent as part of a removal or disposal procedure.
摘要翻译：通过提供将可滥用物质与单独的抗滥用物质试剂相结合的系统和方法作为去除或处理程序的一部分，减少了残留在使用过的皮肤磨损块中的残留量的可滥用物质的潜在的药物滥用。

5. 发明申请

US20100324470A1 Dosage Control Electrode for Iontophoresis Device 有权
标题翻译：离子电渗装置用量控制电极
公开(公告)号：US20100324470A1
公开(公告)日：2010-12-23
申请号：US12868123
申请日：2010-08-25
申请人： Carter R. Anderson , Russell L. Morris
发明人： Carter R. Anderson , Russell L. Morris
IPC分类号： A61N1/30 , A61N1/00
CPC分类号： A61N1/0436 , A61N1/044
摘要： An electrode assembly for use in an iontophoresis device for the transcutaneous administration of an active therapeutic species has a base layer of including a linking conductive base material which is consumed (oxidizes or reduces) preferentially to water, a first upper layer of sacrificial material coated on a first portion of the base layer wherein the sacrificial material is consumed preferentially to the linking conductive base material of the base layer. A second upper layer of non-conducting material is coated on a second portion of the base layer, the second upper layer being spaced from the first upper layer, connected by a narrow exposed linking area of the base layer material remaining exposed therebetween. During operation of an associated iontophoresis device, the sacrificial material will be sequentially consumed; the first upper layer will be fully consumed followed by the linking conductive base material of the exposed linking area of the base layer which severs the base layer thereby breaking circuit continuity disabling activity in the device. A visual indicator may be provided allowing a wearer to monitor the state of reaction of the linking area.
摘要翻译：用于经皮给药活性治疗物种的离子电渗疗法装置的电极组件具有包含优先吸收（氧化或还原）水的连接导电基材的基层，涂覆在第一上层的牺牲材料基底层的第一部分，其中牺牲材料优先地消耗到基底层的连接导电基底材料。第二上层非导电材料被涂覆在基层的第二部分上，第二上层与第一上层隔开，第二上层由保留在其间的基层材料的窄暴露的连接区连接。在相关联的离子电渗装置的操作期间，牺牲材料将被顺序消耗; 第一上层将被完全消耗，之后是基底层的暴露的连接区域的连接导电基底材料，其切断基底层，从而破坏器件中的电路连续性失效活动。可以提供视觉指示器，允许佩戴者监视连接区域的反应状态。

6. 再颁专利

USRE41946E1 Portable immediate response medical analyzer having multiple testing modules 有权
标题翻译：便携式立即响应医疗分析仪，具有多个测试模块
公开(公告)号：USRE41946E1
公开(公告)日：2010-11-23
申请号：US10153081
申请日：2002-05-22
申请人： Carter R. Anderson , David T. Giddings , James D. Kurkowski , Robbi T. Thompson , Kee Van Sin
发明人： Carter R. Anderson , David T. Giddings , James D. Kurkowski , Robbi T. Thompson , Kee Van Sin
IPC分类号： G01N27/327
CPC分类号： G01N33/48785
摘要： A portable device that includes a plurality of test modules for analyzing preselected concentrations of various body fluids of a patient. The portable diagnostic device interfaces and utilizes disposable cartridges and reagent diagnostic test strips and other fluid sample diagnostic devices to determine the amounts of preselected parameters in a patient's blood through either electrochemical, electrical, optical, or mechanical analysis. The disposable fluid sample diagnostic devices may include sample chambers with inlet ports, electrical, physical, or chemical sensors, in situ calibration media, a plurality of electrical interface terminals, and temperature control elements. An electrical interface interconnects the various test modules with one or more corresponding integrated circuits which in turn are electrically coupled to a common interactive display, printer, power supply, and communication ports.
摘要翻译：一种便携式装置，其包括用于分析患者的各种体液的预选浓度的多个测试模块。便携式诊断装置接口并利用一次性药筒和试剂诊断试纸以及其它流体样品诊断装置，以通过电化学，电学，光学或机械分析来确定患者血液中预选参数的量。一次性流体样品诊断装置可以包括具有入口端口，电气，物理或化学传感器，原位校准介质，多个电接口端子和温度控制元件的样品室。电接口将各种测试模块与一个或多个相应的集成电路互连，所述集成电路又电耦合到共同的交互式显示器，打印机，电源和通信端口。

7. 发明申请

US20100068250A1 Abuse Potential Reduction in Abusable Substance Dosage Form 有权
标题翻译：滥用潜在的减少药物滥用形式
公开(公告)号：US20100068250A1
公开(公告)日：2010-03-18
申请号：US12621619
申请日：2009-11-19
申请人： Carter R. Anderson , Russell L. Morris
发明人： Carter R. Anderson , Russell L. Morris
IPC分类号： A61K31/445 , A61K9/70 , A61P25/04
CPC分类号： A62D3/33 , A61J1/00 , A61J1/14 , A61K9/7084 , A61K31/445 , A62D3/00 , A62D2101/26 , B09B3/0075 , B09B2220/14 , B65D25/14
摘要： The potential for substance abuse involving residual amounts of abusable substances remaining in used skin-worn patches is reduced by the provision of a system and method for combining the abusable substance with a separate anti-abuse substance agent as part of a removal or disposal procedure.
摘要翻译：通过提供将可滥用物质与单独的抗滥用物质试剂相结合的系统和方法作为去除或处理程序的一部分，减少了残留在使用过的皮肤磨损块中的残留量的可滥用物质的潜在可能性。

8. 发明申请

US20090180936A1 MEDICATION DISPOSAL SYSTEM 有权
标题翻译：药物处置系统
公开(公告)号：US20090180936A1
公开(公告)日：2009-07-16
申请号：US12412144
申请日：2009-03-26
申请人： Carter R. Anderson , Russell L. Morris
发明人： Carter R. Anderson , Russell L. Morris
IPC分类号： B01J19/00
CPC分类号： A61K9/7023 , A61K31/445 , B09B3/0075 , B09B2220/14
摘要： The potential for environmental release of unused and expired medications is reduced by the provision of a system and method for combining the unused or expired medication with an amount of activated carbon as part of a disposal procedure.
摘要翻译：作为处置程序的一部分，通过提供将未使用或过期的药物与一定量的活性炭组合的系统和方法来减少未使用和过期药物的环境释放的潜力。

9. 发明授权

US6150174A Method for measurement of whole blood coagulation parameters 失效
标题翻译：全血凝固参数测定方法
公开(公告)号：US6150174A
公开(公告)日：2000-11-21
申请号：US34478
申请日：1998-03-04
申请人： Kee Van Sin , Carter R. Anderson
发明人： Kee Van Sin , Carter R. Anderson
IPC分类号： G01N33/49 , G01N33/86
CPC分类号： G01N33/86 , G01N33/4905
摘要： The present invention provides a method for determining the coagulation propensity of blood wherein a condition in a portion of a blood sample is assessed and related to the onset of coagulation. Apparatus for performing the method is encompassed by the invention.
摘要翻译：本发明提供一种用于测定血液凝固倾向的方法，其中评估血液样品的一部分的状况并与凝血的发生相关。用于执行该方法的装置包括在本发明中。

10. 发明授权

US5036861A Method and apparatus for non-invasively monitoring plasma glucose levels 失效
标题翻译：用于非侵入性监测血浆葡萄糖水平的方法和装置
公开(公告)号：US5036861A
公开(公告)日：1991-08-06
申请号：US463387
申请日：1990-01-11
申请人： Walter L. Sembrowich , Carter R. Anderson , William R. Kennedy
发明人： Walter L. Sembrowich , Carter R. Anderson , William R. Kennedy
IPC分类号： A61B5/00 , A61N1/32 , G01N33/66
CPC分类号： G01N33/66 , A61B5/14521 , A61B5/14532 , A61B5/4266 , A61N1/325
摘要： A method and apparatus non-invasively monitor plasma constituent levels. A localized, modified sweating response is induced providing a sweat secretion for analysis of the plasma constituents.
摘要翻译：一种方法和装置非侵入性地监测血浆成分水平。诱发局部的，改良的出汗反应，提供用于分析血浆成分的汗液分泌。

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