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1. 发明授权

US09247912B2 Method, image processing device and computed tomography system for obtaining a 4D image data record of an object under examination and computer program product with program code sections for carrying out a method of this kind 有权
标题翻译：方法，图像处理装置和计算机断层摄影系统，用于获得被检查对象的4D图像数据记录和具有用于执行这种方法的程序代码部分的计算机程序产品
公开(公告)号：US09247912B2
公开(公告)日：2016-02-02
申请号：US13435881
申请日：2012-03-30
申请人： Gabriel Haras , Stefan Thesen , Carsten Thierfelder , Johann Uebler
发明人： Gabriel Haras , Stefan Thesen , Carsten Thierfelder , Johann Uebler
IPC分类号： A61B6/03 , A61B6/04 , A61B6/00 , G06T17/00 , A61B5/0456 , A61B5/00
CPC分类号： A61B6/03 , A61B5/0456 , A61B5/7207 , A61B6/0457 , A61B6/481 , A61B6/486 , A61B6/503 , A61B6/507 , A61B6/541 , G06T17/00 , G06T2200/08 , G06T2210/41
摘要： A method is disclosed for obtaining a 4D image data record of an object under examination using measured data from a computed tomography system in which projection data are accepted which were acquired by way of the computed tomography system at different imaging time points by way of an helical scan method following the administration of contrast medium to the object under examination). On the basis of the projection data, image data of the object under examination are then reconstructed and linked with the imaging time points to a space/time data record. Then, a parameterized 4D image data model is individualized with adaptation to the space/time data record by varying model parameters. An image processing device and a computed tomography system with an image processing device of this kind are also described.
摘要翻译：公开了一种用于使用来自计算机断层摄影系统的测量数据获得被检查物体的4D图像数据记录的方法，其中接受通过计算机断层摄影系统在不同成像时间点通过螺旋将造影剂施用于检查对象之后的扫描方法）。在投影数据的基础上，对被检查对象的图像数据进行重建，并将其与成像时间点连接到空间/时间数据记录。然后，参数化的4D图像数据模型通过改变模型参数而适应空间/时间数据记录来个性化。还描述了具有这种图像处理装置的图像处理装置和计算机断层摄影系统。

2. 发明申请

US20100324434A1 METHOD AND DEVICE FOR ASSISTING IN DETERMINATION OF THE SUITABILITY OF A PATIENT FOR A SCAN OF THE PATIENT'S HEART USING AN X-RAY COMPUTER TOMOGRAPH AND METHOD AND X-RAY COMPUTER TOMOGRAPH FOR SCANNING THE HEART OF A PATIENT 有权
标题翻译：使用X射线计算机TOMOGRAPH和方法以及用于扫描患者心脏的方法和X射线计算机图谱来确定患者心脏扫描患者适合性的方法和装置
公开(公告)号：US20100324434A1
公开(公告)日：2010-12-23
申请号：US12818587
申请日：2010-06-18
申请人： Thomas ALLMENDINGER , Heiko Mehldau , Thomas Seiler , Carsten Thierfelder
发明人： Thomas ALLMENDINGER , Heiko Mehldau , Thomas Seiler , Carsten Thierfelder
IPC分类号： A61B5/0402 , A61B6/03
CPC分类号： A61B5/0456 , A61B6/503 , A61B6/541
摘要： A method is disclosed for assisting in determination of the suitability of a patient for a scan of the heart of the patient using an X-ray computer tomograph. In at least one embodiment of the method, a) an electrocardiogram of the patient is recorded; b) the electrocardiogram is evaluated by predicting the occurrence time of at least the immediately following R wave on the basis of at least four immediately consecutive R waves of the electrocardiogram which were measured last, and comparing this with the actual measured occurrence time of the next R wave; and c) wherein the quality of the prediction is visualized qualitatively. Further, in at least one embodiment, a device is disclosed including an ECG instrument and a computation device for carrying out the method. At least one embodiment of the invention furthermore relates to a method and a device for scanning the heart of a patient on the basis of a prediction of R waves.
摘要翻译：公开了一种用于帮助确定患者对于使用X射线计算机断层摄影术对患者心脏进行扫描的适合性的方法。在该方法的至少一个实施例中，a）记录患者的心电图; b）通过基于最后测量的至少四个紧邻的心电图的R波来预测至少紧随其后的R波的发生时间来评估心电图，并将其与下一次的实际测量的发生时间进行比较 R波; 和c）其中预测的质量被定性可视化。此外，在至少一个实施例中，公开了一种包括用于执行该方法的ECG仪器和计算装置的装置。本发明的至少一个实施例还涉及一种用于基于R波的预测来扫描患者的心脏的方法和装置。

3. 发明申请

US20060082774A1 Reference body for alignment of laser projectors and an image data acquisition system, and tomography apparatus including same 审中-公开
标题翻译：用于对准激光投影仪的参考体和图像数据采集系统，以及包括其的断层摄影装置
公开(公告)号：US20060082774A1
公开(公告)日：2006-04-20
申请号：US11243230
申请日：2005-10-04
申请人： Thorsten Buttner , Winfried Korber , Carsten Thierfelder
发明人： Thorsten Buttner , Winfried Korber , Carsten Thierfelder
IPC分类号： G01B11/00
CPC分类号： A61B6/583 , A61B6/032 , A61B6/08
摘要： A reference body for alignment of laser projectors and an acquisition system of a tomography apparatus relative to one another, has at least two reference indicators, with each reference indicator establishing a reference plane. Each reference plane serves for alignment of one of the laser projectors. The at least two reference indicators enable the simultaneous alignment of laser projectors without a shifting of the reference body being necessary. A computed tomography apparatus includes such a reference body
摘要翻译：用于对准激光投影仪的参考体和相对于彼此的断层摄影装置的采集系统具有至少两个参考指示器，每个参考指示器建立参考平面。每个参考平面用于对准一个激光投影仪。至少两个参考指示器使得能够同时对准激光投影仪，而不需要参考体的移动。计算机断层摄影装置包括这样的参考体

4. 发明授权

US08218719B2 Computerized method and processor for selecting acquisition configurations to obtain X-ray computed tomography data 失效
标题翻译：用于选择采集配置以获得X射线计算机断层摄影数据的计算机化方法和处理器
公开(公告)号：US08218719B2
公开(公告)日：2012-07-10
申请号：US12953735
申请日：2010-11-24
申请人： Thomas Allmendinger , Stefan Reichelt , Carsten Thierfelder
发明人： Thomas Allmendinger , Stefan Reichelt , Carsten Thierfelder
IPC分类号： A61B6/03
CPC分类号： A61B6/032 , A61B5/02405 , A61B6/503 , A61B6/504
摘要： In a method to assist in the selection of an acquisition configuration from a set of adjustable acquisition configurations for the acquisition of x-ray projections of the heart of a patient with a computed tomography apparatus to examine the heart of the patient, the which method is based on an examination type to be specified. At least two acquisition configurations for the specified examination type (which acquisition configurations can be adjusted at the computed tomography apparatus) are considered for which at least one probability density function is respectively kept ready that was determined for the respective acquisition configuration for a specific variable pertaining to a person and/or for the x-ray dose to be applied to the person. Using the at least two probability density functions, the acquisition configuration that is best suited for the examination of the heart of the patient according to the specified examination type is determined from the at least two adjustable acquisition configurations under consideration, based on at least one determined variable to be specified and pertaining to the current patient to be examined and/or based on a value pertaining to the applied x-ray dose. The invention also concerns a computed tomography apparatus operable according to such a method and a storage medium encoded with programming instructions for implementing such a method.
摘要翻译：在一种用于利用计算机断层摄影装置获取患者心脏的X射线投影的一组可调采集配置来帮助选择采集配置以检查患者的心脏的方法中，哪个方法是根据要指定的检查类型。考虑用于指定检查类型的至少两个采集配置（在计算机断层摄影装置可以调整采集配置），至少一个概率密度函数分别保持准备就是针对特定变量的各个采集配置确定的对于某人和/或x射线剂量施用于该人。使用至少两个概率密度函数，根据指定的检查类型最适合于检查患者心脏的采集配置基于至少一个确定的变量被指定并属于要检查的当前患者和/或基于与所应用的x射线剂量有关的值。本发明还涉及根据这种方法可操作的计算机断层摄影装置和用编程指令编码的用于实现这种方法的存储介质。

5. 发明申请

US20110129056A1 COMPUTERIZED METHOD AND PROCESSOR FOR SELECTING ACQUISITION CONFIGURATIONS TO OBTAIN X-RAY COMPUTED TOMOGRAPHY DATA 失效
标题翻译：用于选择获取X射线计算机图形数据的获取配置的计算机方法和处理器
公开(公告)号：US20110129056A1
公开(公告)日：2011-06-02
申请号：US12953735
申请日：2010-11-24
申请人： Thomas Allmendinger , Stefan Reichelt , Carsten Thierfelder
发明人： Thomas Allmendinger , Stefan Reichelt , Carsten Thierfelder
IPC分类号： A61B6/03
CPC分类号： A61B6/032 , A61B5/02405 , A61B6/503 , A61B6/504
摘要： In a method to assist in the selection of an acquisition configuration from a set of adjustable acquisition configurations for the acquisition of x-ray projections of the heart of a patient with a computed tomography apparatus to examine the heart of the patient, the which method is based on an examination type to be specified. At least two acquisition configurations for the specified examination type (which acquisition configurations can be adjusted at the computed tomography apparatus) are considered for which at least one probability density function is respectively kept ready that was determined for the respective acquisition configuration for a specific variable pertaining to a person and/or for the x-ray dose to be applied to the person. Using the at least two probability density functions, the acquisition configuration that is best suited for the examination of the heart of the patient according to the specified examination type is determined from the at least two adjustable acquisition configurations under consideration, based on at least one determined variable to be specified and pertaining to the current patient to be examined and/or based on a value pertaining to the applied x-ray dose. The invention also concerns a computed tomography apparatus operable according to such a method and a storage medium encoded with programming instructions for implementing such a method.
摘要翻译：在一种用于利用计算机断层摄影装置获取患者心脏的X射线投影的一组可调采集配置来帮助选择采集配置以检查患者的心脏的方法中，哪个方法是根据要指定的检查类型。考虑用于指定检查类型的至少两个采集配置（在计算机断层摄影装置可以调整采集配置），至少一个概率密度函数分别保持准备就是针对特定变量的各个采集配置确定的对于某人和/或x射线剂量施用于该人。使用至少两个概率密度函数，根据指定的检查类型最适合于检查患者心脏的采集配置基于至少一个确定的变量被指定并属于要检查的当前患者和/或基于与所应用的x射线剂量有关的值。本发明还涉及根据这种方法可操作的计算机断层摄影装置和用编程指令编码的用于实现这种方法的存储介质。

6. 发明申请

US20100260400A1 METHOD AND DATA-PROCESSING SYSTEM FOR DETERMINING THE PROPORTION OF CALCIUM IN CORONARY ARTERIES 有权
标题翻译：用于确定冠状动脉钙的比例的方法和数据处理系统
公开(公告)号：US20100260400A1
公开(公告)日：2010-10-14
申请号：US12729267
申请日：2010-03-23
申请人： Dominik Bernhardt , Jörg Hausleiter , Carsten Thierfelder , Johann Uebler , Fernando Vega-Higuera
发明人： Dominik Bernhardt , Jörg Hausleiter , Carsten Thierfelder , Johann Uebler , Fernando Vega-Higuera
IPC分类号： G06T7/00
CPC分类号： A61B6/481 , A61B5/02007 , A61B6/032 , A61B6/504 , G06T7/0012 , G06T7/11 , G06T7/136 , G06T7/70 , G06T2207/10081 , G06T2207/30048 , G06T2207/30101
摘要： A method and a data-processing system are disclosed for determining the proportion of calcium in coronary arteries using image data from CT angiography. In at least one embodiment of the method, anatomical landmarks are detected in the image data in the region of the heart and coronary arteries are segmented taking into account the detected landmarks. Regions with an increased HU value compared to a contrast agent surroundings are segmented in the segmented coronary arteries. A proportion of calcium respectively is calculated from the segmented regions for one or more of the segmented coronary arteries. At least the last two steps are carried out fully automatically by a data-processing system. Weighting factors for the individual regions are used when calculating the proportion of calcium, which weighting factors depend on both the threshold for segmenting the respective region and the volume of said region. The method and the data-processing system of at least one embodiment allow the dose exposure of the patient to be reduced and reduce the time expenditure of the user for determining the proportion of calcium.
摘要翻译：公开了一种使用来自CT血管造影术的图像数据来确定冠状动脉中钙的比例的方法和数据处理系统。在该方法的至少一个实施例中，在心脏区域中的图像数据中检测解剖标志，并且考虑到检测到的界标来分割冠状动脉。在分割冠状动脉中分割具有与造影剂周围环境相比增加的HU值的区域。对于一个或多个分割冠状动脉的分割区域分别计算一部分钙。至少最后两个步骤由数据处理系统完全自动执行。当计算钙的比例时，使用各个区域的权重因子，该加权因子取决于分割各个区域的阈值和所述区域的体积。至少一个实施方案的方法和数据处理系统允许减少患者的剂量暴露并减少用户确定钙的比例的时间支出。

7. 发明授权

US08699772B2 Scanning of a cyclically moved examination object using a contrast agent within the scope of a preliminary examination by means of a CT scanner 有权
标题翻译：通过CT扫描仪在初步检查范围内使用造影剂扫描循环移动的检查对象
公开(公告)号：US08699772B2
公开(公告)日：2014-04-15
申请号：US12892011
申请日：2010-09-28
申请人： Thomas Allmendinger , Jörg Hausleiter , Heiko Mehldau , Carsten Thierfelder
发明人： Thomas Allmendinger , Jörg Hausleiter , Heiko Mehldau , Carsten Thierfelder
IPC分类号： G06K9/00
CPC分类号： A61B6/481 , A61B5/0456 , A61B6/027 , A61B6/032 , A61B6/4014 , A61B6/4266 , A61B6/466 , A61B6/482 , A61B6/503 , A61B6/504 , A61B6/507 , A61B6/5288 , A61B6/541
摘要： A method is disclosed for scanning a cyclically moved examination object using a contrast agent within the scope of a preliminary examination by way of a CT scanner, in which measurement data is recorded at a sequence of recording times. A first image is reconstructed at every recording time from the measurement data, from which a time profile of a concentration of the contrast agent is established. The recording times for respectively recording a certain phase of the motion are synchronized with a motion signal from the examination object. A second image with a time offset with respect to the first image is reconstructed from the measurement data at each recording time. A motion curve representing a time profile of an intensity of the cyclical motion is established by comparing the first image and the second image at each recording time.
摘要翻译：公开了一种用于通过CT扫描仪在初步检查范围内使用造影剂扫描循环移动的检查对象的方法，其中测量数据以记录次序记录。在每个记录时间从测量数据重建第一图像，从中建立造影剂的浓度的时间曲线。用于分别记录运动的某一相位的记录时间与来自检查对象的运动信号同步。在每个记录时间从测量数据重建相对于第一图像具有时间偏移的第二图像。通过在每个记录时间比较第一图像和第二图像来建立表示循环运动强度的时间曲线的运动曲线。

8. 发明授权

US08718342B2 Method and data-processing system for determining the proportion of calcium in coronary arteries 有权
标题翻译：确定冠状动脉钙含量的方法和数据处理系统
公开(公告)号：US08718342B2
公开(公告)日：2014-05-06
申请号：US12729267
申请日：2010-03-23
申请人： Dominik Bernhardt , Jörg Hausleiter , Carsten Thierfelder , Johann Uebler , Fernando Vega-Higuera
发明人： Dominik Bernhardt , Jörg Hausleiter , Carsten Thierfelder , Johann Uebler , Fernando Vega-Higuera
IPC分类号： G06K9/00
CPC分类号： A61B6/481 , A61B5/02007 , A61B6/032 , A61B6/504 , G06T7/0012 , G06T7/11 , G06T7/136 , G06T7/70 , G06T2207/10081 , G06T2207/30048 , G06T2207/30101
摘要： A method and a data-processing system are disclosed for determining the proportion of calcium in coronary arteries using image data from CT angiography. In at least one embodiment of the method, anatomical landmarks are detected in the image data in the region of the heart and coronary arteries are segmented taking into account the detected landmarks. Regions with an increased HU value compared to a contrast agent surroundings are segmented in the segmented coronary arteries. A proportion of calcium respectively is calculated from the segmented regions for one or more of the segmented coronary arteries. At least the last two steps are carried out fully automatically by a data-processing system. Weighting factors for the individual regions are used when calculating the proportion of calcium, which weighting factors depend on both the threshold for segmenting the respective region and the volume of said region. The method and the data-processing system of at least one embodiment allow the dose exposure of the patient to be reduced and reduce the time expenditure of the user for determining the proportion of calcium.
摘要翻译：公开了一种使用来自CT血管造影术的图像数据来确定冠状动脉中钙的比例的方法和数据处理系统。在该方法的至少一个实施例中，在心脏区域中的图像数据中检测解剖标志，并且考虑到检测到的界标来分割冠状动脉。在分割冠状动脉中分割具有与造影剂周围环境相比增加的HU值的区域。对于一个或多个分割冠状动脉的分割区域分别计算一部分钙。至少最后两个步骤由数据处理系统完全自动执行。当计算钙的比例时，使用各个区域的权重因子，该加权因子取决于分割各个区域的阈值和所述区域的体积。至少一个实施方案的方法和数据处理系统允许减少患者的剂量暴露并减少用户确定钙的比例的时间支出。

9. 发明申请

US20090124892A1 Method for measuring cardiac perfusion in a patient and CT system for carrying out the method 审中-公开
标题翻译：用于测量患者和CT系统中心脏灌注的方法，用于执行该方法
公开(公告)号：US20090124892A1
公开(公告)日：2009-05-14
申请号：US12289441
申请日：2008-10-28
申请人： Herbert Bruder , Karl Stierstorfer , Carsten Thierfelder
发明人： Herbert Bruder , Karl Stierstorfer , Carsten Thierfelder
IPC分类号： A61B6/03
CPC分类号： A61B6/481 , A61B6/503 , A61B6/507 , A61B6/541 , A61B6/589 , G01R33/5601 , G01R33/56366
摘要： A method and a CT system are disclosed for measuring the perfusion in vessels and/or muscles of the heart (cardiac perfusion) in a patient. In at least one embodiment of the method the patient receives a contrast agent bolus, the patient is scanned for a scan period of a plurality of cardiac cycles in a scan field of a CT system controlled by the cardiac rhythm, a plurality of CT image data is reconstructed from projection data of a particular cardiac phase from respectively one cardiac cycle, and the temporal profile of the absorption values at at least one location in the heart is determined and displayed on the basis of a plurality of CT image data at successive times. At least one embodiment of the invention is distinguished by the fact that during the examination, the patient is repeatedly and alternately moved in opposite directions along a system axis of the CT system such that his cardiac region passes through the scan field at a cardiac phase range and the cardiac region is completely scanned spirally.
摘要翻译：公开了用于测量患者血管和/或心脏肌肉（心脏灌注）的灌注的方法和CT系统。在该方法的至少一个实施方案中，患者接受造影剂推注，在由心律控制的CT系统的扫描场中扫描患者多个心动周期的扫描周期，多个CT图像数据从特定心脏相位的投影数据分别从一个心动周期重构，并且基于连续的多个CT图像数据来确定和显示心脏中至少一个位置处的吸收值的时间分布。本发明的至少一个实施例的特征在于，在检查期间，患者沿着CT系统的系统轴线沿相反方向重复地和交替地移动，使得他的心脏区域在心脏相位范围内通过扫描场并且心脏区域被螺旋地完全扫描。

10. 发明授权

US08611987B2 Method and device for assisting in determination of the suitability of a patient for a scan of the patient's heart using an X-ray computer tomograph and method and X-ray computer tomograph for scanning the heart of a patient 有权
标题翻译：用于使用X射线计算机断层摄影机和方法以及用于扫描患者心脏的X射线计算机断层扫描仪来帮助确定患者对患者心脏扫描的适合性的方法和装置
公开(公告)号：US08611987B2
公开(公告)日：2013-12-17
申请号：US12818587
申请日：2010-06-18
申请人： Thomas Allmendinger , Heiko Mehldau , Thomas Seiler , Carsten Thierfelder
发明人： Thomas Allmendinger , Heiko Mehldau , Thomas Seiler , Carsten Thierfelder
IPC分类号： A61B5/05
CPC分类号： A61B5/0456 , A61B6/503 , A61B6/541
摘要： A method is disclosed for assisting in determination of the suitability of a patient for a scan of the heart of the patient using an X-ray computer tomograph. In at least one embodiment of the method, a) an electrocardiogram of the patient is recorded; b) the electrocardiogram is evaluated by predicting the occurrence time of at least the immediately following R wave on the basis of at least four immediately consecutive R waves of the electrocardiogram which were measured last, and comparing this with the actual measured occurrence time of the next R wave; and c) wherein the quality of the prediction is visualized qualitatively. Further, in at least one embodiment, a device is disclosed including an ECG instrument and a computation device for carrying out the method. At least one embodiment of the invention furthermore relates to a method and a device for scanning the heart of a patient on the basis of a prediction of R waves.
摘要翻译：公开了一种用于帮助确定患者对于使用X射线计算机断层摄影术对患者心脏进行扫描的适合性的方法。在该方法的至少一个实施例中，a）记录患者的心电图; b）通过基于最后测量的至少四个紧邻的心电图的R波来预测至少紧随其后的R波的发生时间来评估心电图，并将其与下一次的实际测量的发生时间进行比较 R波; 和c）其中预测的质量被定性可视化。此外，在至少一个实施例中，公开了一种包括用于执行该方法的ECG仪器和计算装置的装置。本发明的至少一个实施例还涉及一种用于基于R波的预测来扫描患者的心脏的方法和装置。

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