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1. 发明申请

WO2006007410A2 MINIMALLY INVASIVE CORING VEIN HARVESTER 审中-公开
标题翻译：最小的入侵角钢收割机
公开(公告)号：WO2006007410A2
公开(公告)日：2006-01-19
申请号：PCT/US2005/021361
申请日：2005-06-16
申请人： MEDTRONIC, INC. , BONNER, Matthew, D. , KEOGH, James, R. , BRISCOE, Roderick, E. , JOLLY, Katherine, S. , USHER, Raymond, W. , BUHR, Rebecca, A. , CHRISTIAN, Steven, C. , CLAGUE, Cynthia, T. , HOBDAY, Michael, J. , JAHNS, Scott, E. , HAARSTAD, Philip, J. , DAIGLE, Tom, P. , REETZ, Robert, H. , SANDSTROM, Jeffrey, D.
发明人： BRISCOE, Roderick, E. , JOLLY, Katherine, S. , USHER, Raymond, W. , BUHR, Rebecca, A. , CHRISTIAN, Steven, C. , CLAGUE, Cynthia, T. , HOBDAY, Michael, J. , JAHNS, Scott, E. , HAARSTAD, Philip, J. , DAIGLE, Tom, P. , REETZ, Robert, H. , SANDSTROM, Jeffrey, D.
IPC分类号： A61B17/00
CPC分类号： A61B17/22 , A61B17/00008 , A61B17/320016 , A61B17/32002 , A61B17/32053 , A61B2017/00557 , A61B2017/00778 , A61B2017/22062 , A61B2017/22068
摘要： The invention provides a system and method for harvesting a vessel section. The system comprises a vessel support member, a handle, and a tubular cutting device. The vessel support member is introduced into the vessel section to be harvested. The tubular cutting device may comprise an outer tubular member or an outer and an inner tubular member. The outer tubular member carries at least one cutting element. The tubular member or members are advanced over the vessel section and vessel support member to core out the vessel section and tissue adjoining the vessel section.
摘要翻译：本发明提供了一种收集血管部分的系统和方法。该系统包括容器支撑构件，手柄和管状切割装置。将容器支撑构件引入待收获的容器部分。管状切割装置可以包括外部管状构件或外部管状构件和内部管状构件。外部管状构件承载至少一个切割元件。管状构件在容器部分和容器支撑构件上前进，以将与容器部分相邻的容器部分和组织芯出。

2. 发明申请

WO2012054776A1 MITRAL BIOPROSTHESIS WITH LOW VENTRICULAR PROFILE 审中-公开
标题翻译：具有低通气剖面的麻醉生物学
公开(公告)号：WO2012054776A1
公开(公告)日：2012-04-26
申请号：PCT/US2011/057170
申请日：2011-10-20
申请人： MEDTRONIC INC , KOVALSKY, Igor , CLAGUE, Cynthia T.
发明人： KOVALSKY, Igor , CLAGUE, Cynthia T.
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2220/0016 , A61F2230/0013 , A61F2230/0054 , A61F2230/008 , A61F2250/0039 , A61F2250/0063
摘要： A heart valve prosthesis configured for placement at a mitral valve in the heart is disclosed that includes a stent-like support structure for supporting a prosthetic mitral valve. The support structure is configured to have a low ventricular profile with only a short length thereof protruding into the left ventricle when deployed in vivo. The support structure includes an upstream section that is outwardly expandable to sit against the atrial wall so as to at least partially anchor the prosthesis therein and a downstream section to which the prosthetic mitral valve is coupled that extends between the left atria and ventricle through the native mitral valve. The low-ventricular profile of the prosthesis is achieved by shaping the support structure such that the downstream section extends within and overlaps with the upstream section at given regions around the circumference of the support structure in an expanded configuration.
摘要翻译：公开了一种配置用于置于心脏二尖瓣的心脏瓣膜假体，其包括用于支撑假体二尖瓣的支架状支撑结构。支撑结构被配置为具有低的心室轮廓，当在体内部署时，其仅具有短的长度突出到左心室。所述支撑结构包括上游部分，所述上游部分向外可扩张以抵靠所述心房壁，以至少部分地将所述假体锚定在其中并且所述假性二尖瓣联接的下游部分在所述左心房和心室之间延伸穿过所述天然二尖瓣通过使支撑结构成形来实现假体的低心室轮廓，使得下游部分在扩展构型中在支撑结构的圆周周围的给定区域处与上游部分延伸并重叠。

3. 发明申请

WO2010123734A2 SYSTEM AND METHOD FOR CLOSURE OF AN INTERNAL OPENING IN TISSUE, SUCH AS A TRANS-APICAL ACCESS OPENING 审中-公开
标题翻译：用于关闭组织内部开放的系统和方法，例如转接开关
公开(公告)号：WO2010123734A2
公开(公告)日：2010-10-28
申请号：PCT/US2010/031074
申请日：2010-04-14
申请人： MEDTRONIC INC. , AHLBERG, Sarah , SIMMA, Sara , ROTHSTEIN, Paul T. , CLEMENTS, Martin , JELICH, Damian , LASKE, Timothy G. , CLAGUE, Cynthia , GREEN, Michael , IAIZZO, Paul
发明人： AHLBERG, Sarah , SIMMA, Sara , ROTHSTEIN, Paul T. , CLEMENTS, Martin , JELICH, Damian , LASKE, Timothy G. , CLAGUE, Cynthia , GREEN, Michael , IAIZZO, Paul
IPC分类号： A61B17/04
CPC分类号： A61B17/0401 , A61B2017/00243 , A61B2017/00663 , A61B2017/00867 , A61B2017/0441 , A61B2017/0443 , A61B2017/0464 , A61B2017/1142
摘要： A method for closing an opening at a target site including bodily tissue including embedding a plurality of self-closing clips into the target site in a spaced apart manner about a perimeter of the opening. Each of the clips has opposing clip ends and an intermediate segment. A flexible tether is coupled to the embedded clips to form a loop about the opening perimeter. A pulling force is applied onto at least one of the loop ends, thereby drawing the perimeter of the opening onto itself to completely close the opening. The loop ends are secured to maintain the target site in a closed state. In some embodiments, the target site is apical cardiac tissue, and the method is performed as part of a trans-apical access procedure.
摘要翻译：一种用于在包括身体组织在内的目标位置处关闭开口的方法，包括围绕开口的周边以间隔开的方式将多个自闭合夹子嵌入目标部位。每个夹子具有相对的夹子端部和中间部分。柔性系绳联接到嵌入的夹子上以围绕开口周边形成环。将拉力施加到至少一个环端，从而将开口的周边拉到其上以完全关闭开口。环路端部被固定以将目标部位保持在关闭状态。在一些实施方案中，靶位点是心尖心脏组织，并且该方法作为跨顶部进入程序的一部分进行。

4. 发明申请

WO2005072624A2 VESSEL SEALING DEVICES 审中-公开
标题翻译： VESSEL密封装置
公开(公告)号：WO2005072624A2
公开(公告)日：2005-08-11
申请号：PCT/US2005/000224
申请日：2005-01-05
申请人： MEDTRONIC, INC. , JAHNS, Scott, E. , KEOGH, Jams, R. , PIGNATO, Paul, A. , OLIG, Christopher , MONTPETIT, Karen, P. , CLAGUE, Cynthia, T. , USHER, Raymond, W. , HAARSTAD, Philip, J. , GUENST, Gary, W.
发明人： JAHNS, Scott, E. , KEOGH, Jams, R. , PIGNATO, Paul, A. , OLIG, Christopher , MONTPETIT, Karen, P. , CLAGUE, Cynthia, T. , USHER, Raymond, W. , HAARSTAD, Philip, J. , GUENST, Gary, W.
IPC分类号： A61B17/00
CPC分类号： A61B17/32053 , A61B17/0482 , A61B17/11 , A61B2017/1107 , A61B2017/1135 , A61B2017/1139
摘要： A device for temporarily sealing an opening in a blood vessel is provided. The device comprises a cutting mechanism for creating an opening in a blood vessel and a seal for sealing the opening in the blood vessel. The seal is delivered through an inner lumen of a tool body coupled to the cutting mechanism. Methods for using the device to construct an anastomosis between two vessels are also provided.
摘要翻译：提供了用于临时密封血管中的开口的装置。该装置包括用于在血管中形成开口的切割机构和用于密封血管中的开口的密封件。密封件通过联接到切割机构的工具主体的内腔传送。还提供了使用该装置来构建两个血管之间的吻合的方法。

5. 发明申请

WO2011031552A1 PARAVALVULAR LEAK CLOSURE DEVICES AND METHODS 审中-公开
标题翻译：旁路泄漏封闭装置及方法
公开(公告)号：WO2011031552A1
公开(公告)日：2011-03-17
申请号：PCT/US2010/046985
申请日：2010-08-27
申请人： MEDTRONIC INC. , ROTHSTEIN, Paul, T. , BERGIN, Cathleen, A. , CLAGUE, Cynthia, T. , GREEN, Michael, M. , HILL, Alexander, J. , KEOGH, James, R. , LASKE, Timothy, G.
发明人： ROTHSTEIN, Paul, T. , BERGIN, Cathleen, A. , CLAGUE, Cynthia, T. , GREEN, Michael, M. , HILL, Alexander, J. , KEOGH, James, R. , LASKE, Timothy, G.
IPC分类号： A61B18/14
CPC分类号： A61B18/1477 , A61B18/1492 , A61B2018/00011 , A61B2018/143 , A61B2218/002 , A61B2218/007 , A61F2/82
摘要： An ablation catheter including an inner tube having a length, a distal end and a longitudinal axis, a plurality of needles extending from the distal end of the inner tube and biased away from the longitudinal axis, an outer sheath slideably moveable relative to the inner tube to surround at least a portion of the length of the inner tube and its extending needles, and a radio frequency energy source electrically connected to the plurality of needles.
摘要翻译：一种消融导管，其包括具有长度，远端和纵向轴线的内管，从所述内管的远端延伸并偏离所述纵向轴线的多个针，相对于所述内管可滑动地移动的外护套以围绕内管及其延伸针的长度的至少一部分，以及电连接到多个针的射频能量源。

6. 发明申请

WO2006007410A3 MINIMALLY INVASIVE CORING VEIN HARVESTER 审中-公开
标题翻译：最小的入侵角钢收割机
公开(公告)号：WO2006007410A3
公开(公告)日：2007-04-19
申请号：PCT/US2005021361
申请日：2005-06-16
申请人： MEDTRONIC INC , BONNER MATTHEW D , KEOGH JAMES R , BRISCOE RODERICK E , JOLLY KATHERINE S , USHER RAYMOND W , BUHR REBECCA A , CHRISTIAN STEVEN C , CLAGUE CYNTHIA T , HOBDAY MICHAEL J , JAHNS SCOTT E , HAARSTAD PHILIP J , DAIGLE TOM P , REETZ ROBERT H , SANDSTROM JEFFREY D
发明人： BRISCOE RODERICK E , JOLLY KATHERINE S , USHER RAYMOND W , BUHR REBECCA A , CHRISTIAN STEVEN C , CLAGUE CYNTHIA T , HOBDAY MICHAEL J , JAHNS SCOTT E , HAARSTAD PHILIP J , DAIGLE TOM P , REETZ ROBERT H , SANDSTROM JEFFREY D
IPC分类号： A61B17/00
CPC分类号： A61B17/22 , A61B17/00008 , A61B17/320016 , A61B17/32002 , A61B17/32053 , A61B2017/00557 , A61B2017/00778 , A61B2017/22062 , A61B2017/22068
摘要： The invention provides a system and method for harvesting a vessel section. The system comprises a vessel support member, a handle, and a tubular cutting device. The vessel support member is introduced into the vessel section to be harvested. The tubular cutting device may comprise an outer tubular member or an outer and an inner tubular member. The outer tubular member carries at least one cutting element. The tubular member or members are advanced over the vessel section and vessel support member to core out the vessel section and tissue adjoining the vessel section.
摘要翻译：本发明提供了一种收集血管部分的系统和方法。该系统包括容器支撑构件，手柄和管状切割装置。将容器支撑构件引入待收获的容器部分。管状切割装置可以包括外部管状构件或外部管状构件和内部管状构件。外部管状构件承载至少一个切割元件。管状构件在容器部分和容器支撑构件上前进，以将与容器部分相邻的容器部分和组织芯出。

7. 发明申请

WO2010123734A3 SYSTEM AND METHOD FOR CLOSURE OF AN INTERNAL OPENING IN TISSUE, SUCH AS A TRANS-APICAL ACCESS OPENING 审中-公开
标题翻译：用于关闭组织内部开放的系统和方法，例如转接开关
公开(公告)号：WO2010123734A3
公开(公告)日：2011-01-27
申请号：PCT/US2010031074
申请日：2010-04-14
申请人： MEDTRONIC INC , AHLBERG SARAH , SIMMA SARA , ROTHSTEIN PAUL T , CLEMENTS MARTIN , JELICH DAMIAN , LASKE TIMOTHY G , CLAGUE CYNTHIA , GREEN MICHAEL , IAIZZO PAUL
发明人： AHLBERG SARAH , SIMMA SARA , ROTHSTEIN PAUL T , CLEMENTS MARTIN , JELICH DAMIAN , LASKE TIMOTHY G , CLAGUE CYNTHIA , GREEN MICHAEL , IAIZZO PAUL
IPC分类号： A61B17/04
CPC分类号： A61B17/0401 , A61B2017/00243 , A61B2017/00663 , A61B2017/00867 , A61B2017/0441 , A61B2017/0443 , A61B2017/0464 , A61B2017/1142
摘要： A method for closing an opening at a target site including bodily tissue including embedding a plurality of self-closing clips (30) into the target site in a spaced apart manner about a perimeter of the opening. Each of the clips has opposing clip ends (56,58) and an intermediate segment (50). A flexible tether (24) is coupled to the embedded clips to form a loop about the opening perimeter. A pulling force is applied onto at least one of the loop ends, thereby drawing the perimeter of the opening onto itself to completely close the opening. The loop ends are secured to maintain the target site in a closed state. In some embodiments, the target site is apical cardiac tissue, and the method is performed as part of a trans-apical access procedure.
摘要翻译：一种用于在包括身体组织的目标位置处关闭开口的方法，包括围绕开口的周边以间隔开的方式将多个自闭合夹子（30）嵌入到目标部位中。每个夹具具有相对的夹端（56,58）和中间段（50）。柔性系绳（24）联接到嵌入的夹子以形成围绕开口周界的环。将拉力施加到至少一个环端，从而将开口的周边拉到其上以完全关闭开口。环路端部被固定以将目标部位保持在关闭状态。在一些实施方案中，靶位点是心尖心脏组织，并且该方法作为跨顶部进入程序的一部分进行。

8. 发明申请

WO2009108464A1 SURGICAL FASTENING CLIPS, SYSTEMS AND METHODS FOR PROXIMATING TISSUE 审中-公开
标题翻译：外科急救夹具，系统和方法用于接受组织
公开(公告)号：WO2009108464A1
公开(公告)日：2009-09-03
申请号：PCT/US2009/032952
申请日：2009-02-03
申请人： MEDTRONIC , INC. , CLAGUE, Cynthia, T. , STEWART, Mark, T. , GREEN, Michael, M. , ROTHSTEIN, Paul, T. , JELICH, Damian, A. , NAYAK, Asha, S. , TORRIANNI, Mark, W. , COPPIN, Chris, M. , HUYNH, Rany , MEYER, Eric, A. , LIDDICOAT, John, R. , LASKE, Timothy, G.
发明人： CLAGUE, Cynthia, T. , STEWART, Mark, T. , GREEN, Michael, M. , ROTHSTEIN, Paul, T. , JELICH, Damian, A. , NAYAK, Asha, S. , TORRIANNI, Mark, W. , COPPIN, Chris, M. , HUYNH, Rany , MEYER, Eric, A. , LIDDICOAT, John, R. , LASKE, Timothy, G.
IPC分类号： A61B17/00 , A61B17/08 , A61B17/064
CPC分类号： A61B17/0057 , A61B17/068 , A61B2017/00243 , A61B2017/00575 , A61B2017/00623 , A61B2017/00867 , A61B2017/0649 , A61B2017/081
摘要： A surgical fastener clip (20) for proximating tissue, the clip providing an undeflected state in which the clip comprises a center portion (22), a, first leg (24), and a second leg (26). The center portion has a perimeter (28) defining a circle-like shape. The legs (24,26) project outwardly relative to the perimeter from a point of departure to a tip (30,32). Extension of each of the legs relative to the perimeter defines an identical wind direction that is either clockwise or counterclockwise. The clip optionally includes a linear cross-member (60) extending across the perimeter (28). The surgical clip can be formed by a wire (70) that is partially wound onto itself in a spiral-like fashion, with the center portion (22) and the legs (24,26) being co-planar in the undeflected state. During use, the clip is rotated, drawing tissue into the center portion. Systems incorporating the clip are also provided.
摘要翻译：一种用于接近组织的手术紧固夹（20），所述夹提供未偏转状态，其中夹具包括中心部分（22），第一腿部（24）和第二腿部（26）。中心部分具有限定圆形形状的周边（28）。腿部（24,26）从出发点向尖端（30,32）相对于周边向外突出。每个腿相对于周边的延伸限定了顺时针或逆时针方向相同的风向。夹子可选地包括横跨周边（28）延伸的线性横向构件（60）。手术夹可以由线（70）形成，线（70）以螺旋状的方式部分地缠绕在自身上，中心部分（22）和腿部（24,26）在未偏转状态下是共面的。在使用过程中，夹子旋转，将纸巾拉入中心部分。还提供了结合夹子的系统。

9. 发明申请

WO2005072624A3 VESSEL SEALING DEVICES 审中-公开
标题翻译： VESSEL密封装置
公开(公告)号：WO2005072624A3
公开(公告)日：2005-11-10
申请号：PCT/US2005000224
申请日：2005-01-05
申请人： MEDTRONIC INC , JAHNS SCOTT E , KEOGH JAMS R , PIGNATO PAUL A , OLIG CHRISTOPHER , MONTPETIT KAREN P , CLAGUE CYNTHIA T , USHER RAYMOND W , HAARSTAD PHILIP J , GUENST GARY W
发明人： JAHNS SCOTT E , KEOGH JAMS R , PIGNATO PAUL A , OLIG CHRISTOPHER , MONTPETIT KAREN P , CLAGUE CYNTHIA T , USHER RAYMOND W , HAARSTAD PHILIP J , GUENST GARY W
IPC分类号： A61B17/00 , A61B17/04 , A61B17/11 , A61B17/32
CPC分类号： A61B17/32053 , A61B17/0482 , A61B17/11 , A61B2017/1107 , A61B2017/1135 , A61B2017/1139
摘要： A device (100) for temporarily sealing an opening in a blood vessel is provided. The device comprises a cutting mechanism (140) for creating an opening in a blood vessel and a seal (8110,114) for sealing the opening in the blood vessel. The seal is delivered through an inner lumen of a tool body (135) coupled to the cutting mechanism.
摘要翻译：提供了用于临时密封血管中的开口的装置（100）。该装置包括用于在血管中形成开口的切割机构（140）和用于密封血管中的开口的密封件（8110,114）。密封件通过联接到切割机构的工具主体（135）的内腔传送。

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