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1. 发明申请

US20100324576A1 Plaque removal device with rotatable cutting element 审中-公开
标题翻译：具有旋转切割元件的斑块去除装置
公开(公告)号：US20100324576A1
公开(公告)日：2010-12-23
申请号：US12871780
申请日：2010-08-30
申请人： Rafael Pintor , Bradley Steven Culbert , Harold Alexander Heitzmann , Bruce D. Stambaugh
发明人： Rafael Pintor , Bradley Steven Culbert , Harold Alexander Heitzmann , Bruce D. Stambaugh
IPC分类号： A61B17/22
CPC分类号： A61B17/320758 , A61B2017/00022 , A61B2017/00685 , A61B2017/22039 , A61B2017/22052 , A61B2017/22068 , A61B2017/22071 , A61B2017/320004 , A61B2017/320008 , A61B2017/320032 , A61B2017/320775
摘要： An elongate tubular body with a rotatable cutting element is provided. An opening is provided near the distal end of the tubular body, and the cutting element may be partially exposed through the opening. The cutting element is configured to remove plaque from the wall of a body lumen. A distal segment may coupled to the distal end of the tubular body and may have a distal port for slidably receiving a guidewire therethrough.
摘要翻译：提供具有可旋转切割元件的细长管状体。在管状体的远端附近设置有开口，并且切割元件可以部分地通过开口露出。切割元件构造成从体腔的壁去除斑块。远侧段可以联接到管状体的远端并且可以具有用于可滑动地容纳穿过其中的导丝的远端口。

2. 发明授权

US5919200A Balloon catheter for abrading a patent foramen ovale and method of using the balloon catheter 有权
标题翻译：用于研磨卵孔卵泡的气囊导管和使用气囊导管的方法
公开(公告)号：US5919200A
公开(公告)日：1999-07-06
申请号：US169142
申请日：1998-10-09
申请人： Bruce D. Stambaugh , Hien V. Nguyen
发明人： Bruce D. Stambaugh , Hien V. Nguyen
IPC分类号： A61B17/22 , A61B17/32 , A61F2/958
CPC分类号： A61B17/320725 , A61B2017/00575 , A61B2017/22061 , A61B2017/320004 , A61M2025/1086 , A61M25/10
摘要： The present invention provides a device and method for closing a patent foramen ovale. The present invention comprises a catheter sheath with proximal and distal ends. A balloon catheter with a plurality of abrasive members is deployably retained within the catheter sheath. Once the catheter sheath is placed by a treating health care professional across a patent foramen ovale, the balloon catheter is advanced such that the balloon and the abrasive members are deployed outside of the distal end of the catheter sheath. The catheter sheath is then removed from the foramen ovale and the balloon is inflated. The treating healthcare professional then abrades the inner surfaces of the patent foramen ovale to thereby cause an area of thrombogenesis. The balloon catheter is then deflated and the abrasive members are then repositioned into the distal end of the catheter sheath and then removed from the patient. The thrombogenic area created along the inner surfaces of the patent foramen ovale then creates of thrombus which over time turns into a scar and the foramen ovale is obliterated.
摘要翻译：本发明提供了一种闭合卵孔卵泡的装置和方法。本发明包括具有近端和远端的导管鞘。具有多个研磨部件的气囊导管可部署地保持在导管鞘内。一旦导管鞘被治疗保健专业人员穿过卵孔专利放置，则气囊导管被推进，使得球囊和研磨构件展开在导管鞘的远端的外侧。然后将导管鞘从孔卵巢中取出并且气囊膨胀。治疗保健专业人员然后磨损卵孔卵泡的内表面，从而引起血栓形成的一个区域。然后将气囊导管放气，然后将研磨构件重新定位到导管护套的远端，然后从患者身上取出。沿卵孔卵圆孔的内表面产生的血栓形成区域随之产生血栓，随着时间的推移，血栓形成瘢痕，卵圆孔被消除。

3. 发明授权

US4908278A Severable multilayer thermoplastic film 失效
标题翻译：可切割多层热塑性薄膜
公开(公告)号：US4908278A
公开(公告)日：1990-03-13
申请号：US926371
申请日：1986-10-31
申请人： Ralph H. Bland , William A. Peper , Bruce D. Stambaugh
发明人： Ralph H. Bland , William A. Peper , Bruce D. Stambaugh
IPC分类号： B32B7/02 , B32B27/30 , C09J7/02
CPC分类号： C09J7/0296 , B32B7/02 , C09J2201/162 , Y10T428/239 , Y10T428/31855 , Y10T428/31913 , Y10T428/31928
摘要： A dispensable multilayer film having alternating layers of a ductile material, a brittle material, and optionally an intermediate layer. The film has excellent strength in its longitudinal and transverse directions but can be transversely cut by forces of less than 9 Newtons on the cutters of commercially available table top tape dispensers. At least one surface of the sheet material can be coated with a functional material.
摘要翻译：具有延性材料，脆性材料和任选的中间层的交替层的可分配的多层膜。该膜在其纵向和横向方向上具有优异的强度，但是可以在市售的台式胶带分配器的切割器上横向切割小于9牛顿的力。片材的至少一个表面可以涂覆有功能材料。

4. 发明授权

US06482217B1 Neuro thrombectomy catheter 有权
标题翻译：神经血栓切除术导管
公开(公告)号：US06482217B1
公开(公告)日：2002-11-19
申请号：US09656635
申请日：2000-09-07
申请人： Rafael Pintor , Bradley Steven Culbert , Harold Alexander Heitzmann , Bruce D. Stambaugh
发明人： Rafael Pintor , Bradley Steven Culbert , Harold Alexander Heitzmann , Bruce D. Stambaugh
IPC分类号： A61B1722
CPC分类号： A61B17/320758 , A61B2017/00022 , A61B2017/00685 , A61B2017/22039 , A61B2017/22052 , A61B2017/22068 , A61B2017/22071 , A61B2017/320004 , A61B2017/320008 , A61B2017/320032 , A61B2017/320775
摘要： An elongate tubular body extends between a rotatable cutter and a control. The cutter is connected to the control with a rotatable element. A vacuum is applied through an annular passage defined between the tubular body and the rotatable element. The tubular body has a sufficiently small outside diameter and sufficient kink resistance and pushability to navigate through the internal carotid artery and at least into the M3 segment of the middle cerebral artery.
摘要翻译：细长管状体在可旋转刀具和控制器之间延伸。刀具通过可旋转元件连接到控制器。通过限定在管状体和可旋转元件之间的环形通道施加真空。管状体具有足够小的外径和足够的扭结阻力和推进性，以便穿过颈内动脉并至少进入大脑中动脉的M3段。

5. 发明授权

US5604019A Tear resistant multilayer films and articles incorporating such films 失效
标题翻译：含有这种膜的抗撕裂多层膜和制品
公开(公告)号：US5604019A
公开(公告)日：1997-02-18
申请号：US425911
申请日：1995-04-20
申请人： Ralph H. Bland , James M. Jonza , James D. Smith , Richard C. Allen , Jeffrey F. Bradley , Kenneth B. Smith , Bruce D. Stambaugh
发明人： Ralph H. Bland , James M. Jonza , James D. Smith , Richard C. Allen , Jeffrey F. Bradley , Kenneth B. Smith , Bruce D. Stambaugh
IPC分类号： B32B7/02 , B32B17/10 , B32B27/36 , B32B27/08
CPC分类号： B32B17/10174 , B32B17/10018 , B32B27/36 , B32B7/02 , Y10S428/91 , Y10S428/911 , Y10T428/1443 , Y10T428/1448 , Y10T428/24942 , Y10T428/2495 , Y10T428/24967 , Y10T428/24975 , Y10T428/2848 , Y10T428/31554 , Y10T428/31562 , Y10T428/31565 , Y10T428/31573 , Y10T428/31616 , Y10T428/31623 , Y10T428/31645 , Y10T428/31728 , Y10T428/31732 , Y10T428/31736 , Y10T428/31743 , Y10T428/31757 , Y10T428/31786 , Y10T428/31797 , Y10T428/31909
摘要： A tear resistant film comprises more than five layers situated one on the other in a parallel array. The layers are individually selected from a stiff polyester or copolyester, a ductile polymeric material, and optionally, an intermediate material. The stiff polyester or copolyester is oriented in at least one direction. Tear resistance may be measured in a Graves area test and reflects the ability of the film to absorb energy. The films of the invention are useful in many articles including security control laminates for glazing members.
摘要翻译：抗撕裂膜包含多于五层的平行排列的另一层。这些层分别选自刚性聚酯或共聚酯，延性聚合物材料和任选的中间材料。刚性聚酯或共聚酯在至少一个方向上取向。抗撕裂性可以在格雷夫斯（Graves）区域测试中测量，并反映了薄膜吸收能量的能力。本发明的薄膜在许多制品中是有用的，其中包括用于玻璃制品的安全控制层压板。

6. 发明授权

US08579926B2 Plaque removal device with rotatable cutting element 有权
标题翻译：具有旋转切割元件的斑块去除装置
公开(公告)号：US08579926B2
公开(公告)日：2013-11-12
申请号：US13305000
申请日：2011-11-28
申请人： Rafael Pintor , Bradley Steven Culbert , Harold Alexander Heitzmann , Bruce D. Stambaugh
发明人： Rafael Pintor , Bradley Steven Culbert , Harold Alexander Heitzmann , Bruce D. Stambaugh
IPC分类号： A61B17/22
CPC分类号： A61B17/320758 , A61B2017/00022 , A61B2017/00685 , A61B2017/22039 , A61B2017/22052 , A61B2017/22068 , A61B2017/22071 , A61B2017/320004 , A61B2017/320008 , A61B2017/320032 , A61B2017/320775
摘要： An elongate tubular body with a rotatable cutting element is provided. An opening is provided near the distal end of the tubular body, and the cutting element may be partially exposed through the opening. The cutting element is configured to remove plaque from the wall of a body lumen. A distal segment may be coupled to the distal end of the tubular body and may have a distal port for slidably receiving a guidewire therethrough.
摘要翻译：提供了具有可旋转切割元件的细长管状体。在管状体的远端附近设置有开口，并且切割元件可以部分地通过开口露出。切割元件构造成从体腔的壁去除斑块。远侧段可以联接到管状体的远端，并且可以具有用于可滑动地容纳穿过其中的导丝的远端口。

7. 发明授权

US07235088B2 Neuro thrombectomy catheter 有权
标题翻译：神经血栓切除术导管
公开(公告)号：US07235088B2
公开(公告)日：2007-06-26
申请号：US10200475
申请日：2002-07-19
申请人： Rafael Pintor , Bradley Steven Culbert , Harold Alexander Heitzmann , Bruce D. Stambaugh
发明人： Rafael Pintor , Bradley Steven Culbert , Harold Alexander Heitzmann , Bruce D. Stambaugh
IPC分类号： A61B17/22
CPC分类号： A61B17/320758 , A61B2017/00022 , A61B2017/00685 , A61B2017/22039 , A61B2017/22052 , A61B2017/22068 , A61B2017/22071 , A61B2017/320004 , A61B2017/320008 , A61B2017/320032 , A61B2017/320775
摘要： An elongate tubular body extends between a rotatable cutter and a control. The cutter is connected to the control with a rotatable element. A vacuum is applied through an annular passage defined between the tubular body and the rotatable element. The tubular body has a sufficiently small outside diameter and sufficient kink resistance and pushability to navigate through arteries such as the internal carotid artery.
摘要翻译：细长管状体在可旋转刀具和控制器之间延伸。刀具通过可旋转元件连接到控制器。通过限定在管状体和可旋转元件之间的环形通道施加真空。管状体具有足够小的外径和足够的扭结阻力和推进性能以导航诸如颈内动脉之类的动脉。

8. 发明授权

US06283935B1 Ultrasonic device for providing reversible tissue damage to heart muscle 失效
公开(公告)号：US06283935B1
公开(公告)日：2001-09-04
申请号：US09164420
申请日：1998-09-30
申请人： Michael D. Laufer , Bruce D. Stambaugh , Hien V. Nguyen
发明人： Michael D. Laufer , Bruce D. Stambaugh , Hien V. Nguyen
IPC分类号： A61B1720
CPC分类号： A61B17/320068 , A61B2017/00084 , A61B2017/00247 , A61B2017/22008 , A61B2018/00392
摘要： An ultrasonic medical or surgical device creates holes in heart tissue utilizing an ultrasonic needle or probe. The ultrasonic needle is inserted into heart tissue and activated to cause cavitation of fluid surrounding the needle. The cavitation heats the surrounding tissue and causes reversible tissue damage. The ultrasonic device consists of a transducer, a needle, and a regulator. The device can be a hand held device for external application or may be a catheter device for performing a minimally invasive procedure. A temperature sensor may be positioned on the needle for sensing a temperature of the heart tissue in which the needle has bee inserted.

9. 发明授权

US06106520A Endocardial device for producing reversible damage to heart tissue 失效
标题翻译：用于产生心脏组织可逆损伤的心内膜装置
公开(公告)号：US06106520A
公开(公告)日：2000-08-22
申请号：US163849
申请日：1998-09-30
申请人： Michael D. Laufer , Bruce D. Stambaugh , Hien V. Nguyen
发明人： Michael D. Laufer , Bruce D. Stambaugh , Hien V. Nguyen
IPC分类号： A61B18/04 , A61B18/14
CPC分类号： A61B18/1492 , A61B18/1477 , A61B2018/00392 , A61B2018/00821 , A61B2018/1425
摘要： A minimally invasive medical or surgical device creates holes in heart tissue utilizing a needle connected to an energy source, such a radio frequency generator, a resistive heating source, or a microwave energy source. The needle is inserted into heart tissue from an interior of the heart and activated to heat the surrounding tissue in order to produce reversible tissue damage. The device consists of an energy source and regulator, electric contacts to the energy source, a catheter, and a needle at the distal end of the catheter for delivering energy to the heart tissue. The catheter is fed through the vasculature into the interior of the heart. A temperature sensor may be positioned on the needle for sensing a temperature of the heart tissue in which the needle has been inserted. Preferably, a regulator is connected to the energy source and to the temperature sensor for controlling the temperature of the heart tissue in which the needle has been inserted to about 40.degree. C. to about 60.degree. C. as sensed by the temperature sensor.
摘要翻译：微创医疗或外科手术装置利用连接到能量源的针，如射频发生器，电阻加热源或微波能量源在心脏组织中产生孔。将针从心脏的内部插入心脏组织，并激活以加热周围的组织，以产生可逆的组织损伤。该装置包括能量源和调节器，能量源的电触点，导管以及在导管的远端处的针，用于将能量传递到心脏组织。导管通过脉管系统进入心脏的内部。温度传感器可以位于针上，用于感测针已插入的心脏组织的温度。优选地，调节器连接到能量源和温度传感器，用于将针已被插入的心脏组织的温度控制在由温度传感器感测的约40℃至约60℃。

10. 发明申请

US20120071907A1 PLAQUE REMOVAL DEVICE WITH ROTATABLE CUTTING ELEMENT 有权
标题翻译：带可旋转切割元件的PLAQUE拆卸装置
公开(公告)号：US20120071907A1
公开(公告)日：2012-03-22
申请号：US13305000
申请日：2011-11-28
申请人： Rafael Pintor , Bradley Steven Culbert , Harold Alexander Heitzmann , Bruce D. Stambaugh
发明人： Rafael Pintor , Bradley Steven Culbert , Harold Alexander Heitzmann , Bruce D. Stambaugh
IPC分类号： A61B17/22
CPC分类号： A61B17/320758 , A61B2017/00022 , A61B2017/00685 , A61B2017/22039 , A61B2017/22052 , A61B2017/22068 , A61B2017/22071 , A61B2017/320004 , A61B2017/320008 , A61B2017/320032 , A61B2017/320775
摘要： An elongate tubular body with a rotatable cutting element is provided. An opening is provided near the distal end of the tubular body, and the cutting element may be partially exposed through the opening. The cutting element is configured to remove plaque from the wall of a body lumen. A distal segment may be coupled to the distal end of the tubular body and may have a distal port for slidably receiving a guidewire therethrough.
摘要翻译：提供具有可旋转切割元件的细长管状体。在管状体的远端附近设置有开口，并且切割元件可以部分地通过开口露出。切割元件构造成从体腔的壁去除斑块。远侧段可以联接到管状体的远端，并且可以具有用于可滑动地容纳穿过其中的导丝的远端口。

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