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1. 发明授权

US09283160B2 Stabilization of cosmetic compositions 有权
标题翻译：化妆品组合物的稳定化
公开(公告)号：US09283160B2
公开(公告)日：2016-03-15
申请号：US13144113
申请日：2010-01-28
申请人： Bernd Herzog , Julie Grumelard
发明人： Bernd Herzog , Julie Grumelard
IPC分类号： A61Q17/04 , A61K8/36 , A61K8/37 , A61K8/40 , A61K8/41 , A61K8/49
CPC分类号： A61K8/494 , A61K8/36 , A61K8/37 , A61K8/40 , A61K8/41 , A61K8/411 , A61K8/496 , A61K8/4966 , A61K2800/52 , A61K2800/592 , A61Q17/04
摘要： Disclosed is the Use of UV absorbers selected from (a1) diphenylacrylates; and (a2) specific hydroxyphenyl triazines for stabilizing cosmetic compositions comprising an organic UV absorber selected from (b1) a specific benzophenone derivative, (b2) a specific benzotriazole derivative and (b3) a specific triazine derivative and UV filters selected from (c1) cinnamic acid derivatives; and (c2) dibenzoylmethane derivatives.
摘要翻译：公开了使用选自（a1）二苯基丙烯酸酯的UV吸收剂; 和（a2）用于稳定化妆品组合物的特定羟基苯基三嗪，其包含选自（b1）特定二苯甲酮衍生物，（b2）特定苯并三唑衍生物和（b3）特定三嗪衍生物的有机UV吸收剂和选自（c1）肉桂酸酸衍生物; 和（c2）二苯甲酰甲烷衍生物。

2. 发明授权

US08986662B2 Use of silane and siloxane bis(biphenyl) triazine derivatives as UV absorbers 有权
标题翻译：使用硅烷和硅氧烷双（联苯）三嗪衍生物作为紫外线吸收剂
公开(公告)号：US08986662B2
公开(公告)日：2015-03-24
申请号：US13878763
申请日：2011-10-20
申请人： Barbara Wagner , Bernd Herzog
发明人： Barbara Wagner , Bernd Herzog
IPC分类号： A61K8/00 , A61K8/49 , A61K8/58 , A61K8/898 , A61Q17/04 , C07F7/08
CPC分类号： A61K8/585 , A61K8/898 , A61Q17/04 , C07F7/0838
摘要： Disclosed is the use of silane and siloxane bis(biphenyl)triazine derivatives of formula (1), wherein n is a number from 1 to 4; if n=1, X is *-L-Sil; or a radical of formula (11′), L is a linker selected from a radical of formula (2); R1, R2, R3 independently from each other are C1-C22alkyl; C6-C20aryl; C1-C22alkoxy; or O—C6-C20aryl; R4, R5, R6 and R7 independently from each other are hydrogen; C1-C22alkyl; C6-C20aryl; C1-C22alkoxy; or O—C6-C20aryl; b is a number from 0 to 30; c is a number from 0 to 6; and d is a number from 0 to 1; p is a number from 1 to 250; q is a number from 0 to 250; and Sil, Sil1 and Sil2 independently from each other are a silane-, oligosiloxane or polysiloxane moiety; if n=2, X is a bivalent radical of formula (1a); or (1b); x is a number from 2 to 250; y is a number from 0 to 250; and z is a number from 1 to 50; if n=3, X is a trivalent radical containing a silane-, oligosiloxane or polysiloxane moiety; If n=4, X is a tetravalent radical of formula (1c); and A is a radical of formula (111′) as UV absorbers.
摘要翻译：公开了式（1）的硅烷和硅氧烷双（联苯）三嗪衍生物的用途，其中n为1至4的数; 如果n = 1，X为* -L-Sil; 或式（11'）的基团，L是选自式（2）的基团的连接基团; R 1，R 2，R 3彼此独立地为C 1 -C 22烷基; C6-C20芳基; C1-C22烷氧基; 或O-C6-C20芳基; R4，R5，R6和R7彼此独立地是氢; C 1 -C 22烷基; C6-C20芳基; C1-C22烷氧基; 或O-C6-C20芳基; b是从0到30的数字; c是从0到6的数字; d为0〜1的数; p是从1到250的数字; q是从0到250的数字; 和Sil，Sil1和Sil2彼此独立地是硅烷，低聚硅氧烷或聚硅氧烷部分; 如果n = 2，X是式（1a）的二价基团; 或（1b）; x是从2到250的数字; y是从0到250的数字; z为1〜50的数; 如果n = 3，X是含有硅烷，低聚硅氧烷或聚硅氧烷部分的三价基团; 如果n = 4，X是式（1c）的四价基团; 并且A是作为UV吸收剂的式（111'）基团。

3. 发明授权

US08585782B2 Use of specific bis(biphenyl)triazine derivatives and mixtures thereof as UV absorbers 有权
标题翻译：使用特定的双（联苯）三嗪衍生物及其混合物作为UV吸收剂
公开(公告)号：US08585782B2
公开(公告)日：2013-11-19
申请号：US13822014
申请日：2011-09-09
申请人： Barbara Wagner , Bernd Herzog
发明人： Barbara Wagner , Bernd Herzog
IPC分类号： C09B62/04 , A61Q17/00 , C07D251/24
CPC分类号： A61K8/4966 , A61K2800/5922 , A61Q17/04
摘要： Disclosed is the use of mixtures comprising at least 2 structurally different bis(biphenyl)triazine derivatives of formula (1) as UV absorbers for increasing the UVA protection factor of cosmetic or dermatological compositions. Wherein X and R1-R6 are defined in the claims and in the specification.
摘要翻译：公开了包含至少2种结构不同的式（1）的双（联苯）三嗪衍生物的混合物作为UV吸收剂的用途，用于增加化妆品或皮肤病学组合物的UVA保护因子。其中X和R 1 -R 6在权利要求书和说明书中定义。

4. 发明申请

US20130202542A1 USE OF SILANE AND SILOXANE BIS(BIPHENYL) TRIAZINE DERIVATIVES AS UV ABSORBERS 有权
标题翻译：使用硅烷和硅氧烷双（BIPHENYL）TRIAZINE衍生物作为紫外线吸收剂
公开(公告)号：US20130202542A1
公开(公告)日：2013-08-08
申请号：US13878763
申请日：2011-10-20
申请人： Barbara Wagner , Bernd Herzog
发明人： Barbara Wagner , Bernd Herzog
IPC分类号： A61K8/58 , A61Q17/04 , C07F7/08
CPC分类号： A61K8/585 , A61K8/898 , A61Q17/04 , C07F7/0838
摘要： Disclosed is the use of silane and siloxane bis(biphenyl)triazine derivatives of formula (1), wherein n is a number from 1 to 4; if n=1, X is *-L-Sil; or a radical of formula (11′), L is a linker selected from a radical of formula (2); R1, R2, R3 independently from each other are C1-C22alkyl; C6-C20aryl; C1-C22alkoxy; or O—C6-C20aryl; R4, R5, R6 and R7 independently from each other are hydrogen; C1-C22alkyl; C6-C20aryl; C1-C22alkoxy; or O—C6-C20aryl; b is a number from 0 to 30; c is a number from 0 to 6; and d is a number from 0 to 1; p is a number from 1 to 250; q is a number from 0 to 250; and Sil, Sil1 and Sil2 independently from each other are a silane-, oligosiloxane or polysiloxane moiety; if n=2, X is a bivalent radical of formula (1a); or (1b); x is a number from 2 to 250; y is a number from 0 to 250; and z is a number from 1 to 50; if n=3, X is a trivalent radical containing a silane-, oligosiloxane or polysiloxane moiety; If n=4, X is a tetravalent radical of formula (1c); and A is a radical of formula (111′) as UV absorbers.
摘要翻译：公开了式（1）的硅烷和硅氧烷双（联苯）三嗪衍生物的用途，其中n为1至4的数; 如果n = 1，X为* -L-Sil; 或式（11'）的基团，L是选自式（2）的基团的连接基团; R 1，R 2，R 3彼此独立地为C 1 -C 22烷基; C6-C20芳基; C1-C22烷氧基; 或O-C6-C20芳基; R4，R5，R6和R7彼此独立地是氢; C 1 -C 22烷基; C6-C20芳基; C1-C22烷氧基; 或O-C6-C20芳基; b是从0到30的数字; c是从0到6的数字; d为0〜1的数; p是从1到250的数字; q是从0到250的数字; 和Sil，Sil1和Sil2彼此独立地是硅烷，低聚硅氧烷或聚硅氧烷部分; 如果n = 2，X是式（1a）的二价基团; 或（1b）; x是从2到250的数字; y是从0到250的数字; z为1〜50的数; 如果n = 3，X是含有硅烷，低聚硅氧烷或聚硅氧烷部分的三价基; 如果n = 4，X是式（1c）的四价基团; 并且A是作为UV吸收剂的式（111'）基团。

5. 发明授权

US08393556B2 Preparation of nanoscalar UV absorbers 有权
标题翻译：纳米级紫外线吸收剂的制备
公开(公告)号：US08393556B2
公开(公告)日：2013-03-12
申请号：US12664429
申请日：2008-06-27
申请人： Stefan Müller , Bernd Herzog
发明人： Stefan Müller , Bernd Herzog
IPC分类号： B02C15/00
CPC分类号： C07D251/24 , A61K8/4966 , A61K2800/412 , A61K2800/413 , A61Q17/04 , B82Y5/00
摘要： Disclosed is a method of preparing a composition, comprising a micronized insoluble organic UV absorber, which method comprises grinding the insoluble organic UV absorber, in coarse particle form, in a grinding apparatus comprising yttrium-stabilized zirconium oxide grinding beads, in the presence of alkyl polyglucoside having the formula CnH2n+1O(C6H10O5)xH, in which n is an integer ranging from 8 to 16 and x is the mean polymerisation level of the glucoside moiety (C6H10O5) and ranges from 1.4 to 1.6, or an ester thereof and in the presence of an antifoam agent as dispersingagent auxiliary.
摘要翻译：公开了一种制备组合物的方法，该组合物包含微粉化的不溶性有机UV吸收剂，该方法包括在包含钇稳定的氧化锆研磨珠的研磨装置中，在烷基存在下研磨粗颗粒形式的不溶性有机UV吸收剂具有式C n H 2n + 10（C 6 H 10 O 5）x H的聚葡萄糖苷，其中n是8至16的整数，x是葡萄糖苷部分（C 6 H 10 O 5）的平均聚合水平，范围为1.4至1.6，或其酯，消泡剂作为分散助剂的存在。

6. 发明申请

US20090258041A1 Protection of Oxidizable Agents 审中-公开
标题翻译：氧化剂的保护
公开(公告)号：US20090258041A1
公开(公告)日：2009-10-15
申请号：US12083557
申请日：2006-06-21
申请人： Sebastien Mongiat , Werner Baschong , Bernd Herzog
发明人： Sebastien Mongiat , Werner Baschong , Bernd Herzog
IPC分类号： A61K8/02 , A61P17/02
CPC分类号： A61K31/05 , A61K8/11 , A61K8/14 , A61K8/347 , A61K8/37 , A61K8/375 , A61K8/42 , A61K8/46 , A61K8/466 , A61K8/4926 , A61K8/4966 , A61K8/4973 , A61K8/553 , A61K8/671 , A61K8/676 , A61K31/222 , A61K31/255 , A61K31/34 , A61K31/445 , A61K2800/412 , A61K2800/413 , A61K2800/522 , A61Q1/02 , A61Q5/02 , A61Q11/00 , A61Q17/04 , A61Q19/00 , A61Q19/10
摘要： Formulations for cosmetical or pharmaceutical use contain an antioxidant in encapsulated form and a cosmetically or pharmaceutically acceptable carrier. The antioxidant is selected from carbon bridged hindered phenoles, ester bridged hindered phenoles, amide bridged hindered phenoles, lactones of hindered phenoles, sterically hindered oxylamines and sterically hindered hydroxylamines. The encapsulated antioxidant is of high activity and suitable to protect a further active ingredient, e.g. oxidizable natural substances, vitamins, fragrances, and extracts from plants fungi, algae or animals, from premature degradation, especially when coencapsulated together with the ingredient. The formulations are useful inter alia for the preparation of a cosmetical or pharmaceutical skin care or skin delivery formulation, injectable solution, infusion solution, eye drop, drinking solution, a dietary or enriched food, an oral care formulation, drinking gargles, in-halants, or as a food additive.
摘要翻译：化妆品或药物用途的制剂含有包封形式的抗氧化剂和化妆品或药学上可接受的载体。抗氧化剂选自碳桥接的受阻酚，酯桥接的受阻酚，酰胺桥接的受阻酚，受阻酚的内酯，空间位阻的羟胺和空间位阻羟胺。包封的抗氧化剂具有高活性并且适于保护另外的活性成分，例如，可氧化的天然物质，维生素，香料，以及来自植物真菌，藻类或动物的提取物，过早降解，特别是当与成分一起胶囊时。该制剂尤其用于制备美容或药物皮肤护理或皮肤递送制剂，可注射溶液，输注溶液，滴眼剂，饮用溶液，饮食或富含食物，口腔护理制剂，饮用漱口剂，漱口剂，或作为食品添加剂。

7. 发明申请

US20050155586A1 Apparatus for controlling a pressure in a fuel inflow line 有权
标题翻译：用于控制燃料流入管线中的压力的装置
公开(公告)号：US20050155586A1
公开(公告)日：2005-07-21
申请号：US11040677
申请日：2005-01-20
申请人： Lothar Dickenscheid , Bernd Herzog
发明人： Lothar Dickenscheid , Bernd Herzog
IPC分类号： F02M37/00 , F02M37/10 , F02M59/46 , F02M63/00 , F02M1/00
CPC分类号： F16K15/042 , F02M37/106 , F16K15/028 , F16K17/0406 , F16K17/0413 , F16K17/044
摘要： In an apparatus (12) for controlling a pressure in a fuel inflow line of a motor vehicle, a shutoff valve (20) and a pressure limiting valve (21) are arranged in a connection (19). The connection (19) is arranged between an inflow junction (16) which leads to the inflow line and an outflow junction (17) which is led into a fuel container. The pressure limiting valve (21) opens above a first pressure and throttles the flow of the fuel through the connection (19). The shutoff valve (20) closes above a second pressure, the second pressure being higher than the first pressure. This ensures that, when a fuel delivery unit is at a standstill, the pressure in the inflow line does not exceed the first pressure and that, during operation of the delivery unit, the pressure in the inflow line can rise above the second pressure and an internal combustion engine of the motor vehicle is supplied sufficiently with fuel.
摘要翻译：在用于控制机动车辆的燃料流入管路中的压力的装置（12）中，截止阀（20）和限压阀（21）被布置在连接（19）中。连接件（19）设置在通向流入管线的流入结（16）和被引入燃料容器的流出结（17）之间。压力限制阀（21）在第一压力之上打开并且通过连接件（19）节流燃料的流动。截止阀（20）在第二压力以上闭合，第二压力高于第一压力。这确保了当燃料输送单元处于停止状态时，流入管线中的压力不超过第一压力，并且在输送单元的操作期间，流入管线中的压力可以升高到高于第二压力，并且机动车辆的内燃机被充分地供给燃料。

8. 发明授权

US06384284B1 Biphenyl compounds substituted by camphor or hydantoin derivatives as sunscreen compositions 有权
标题翻译：由樟脑或乙内酰脲衍生物取代的联苯化合物作为防晒组合物
公开(公告)号：US06384284B1
公开(公告)日：2002-05-07
申请号：US09806358
申请日：2001-03-29
申请人： Rudolf Zink , Dieter Reinehr , Helmut Luther , Bernd Herzog
发明人： Rudolf Zink , Dieter Reinehr , Helmut Luther , Bernd Herzog
IPC分类号： C07C4900
CPC分类号： C07C309/24 , A61K8/35 , A61K8/466 , A61K8/4946 , A61Q17/04 , C07C45/74 , C07C49/683
摘要： A description is given of diphenyl compounds of formula wherein R is a camphor or hydantoin derivative; and R1 is hydrogen; or C1-C5alkyl. These compounds are suitable as light stabilizers in cosmetic, pharmaceutical and veterinary formulations.
摘要翻译：给出了二烷基化合物的描述，R是樟脑或乙内酰脲衍生物; 并且R 1是氢; 或C1-C5烷基。这些化合物在化妆品，药物和兽药制剂中适合作为光稳定剂。

9. 发明授权

US06235271B1 UV-protection formulation 失效
标题翻译：紫外线防护配方
公开(公告)号：US06235271B1
公开(公告)日：2001-05-22
申请号：US09122554
申请日：1998-07-24
申请人： Helmut Luther , Albert Stehlin , Bernd Herzog
发明人： Helmut Luther , Albert Stehlin , Bernd Herzog
IPC分类号： A61K742
CPC分类号： A61K8/29 , A61K8/0241 , A61K8/0279 , A61K8/42 , A61K8/4946 , A61K8/496 , A61K8/4966 , A61K8/73 , A61K8/8147 , A61K8/8176 , A61K2800/412 , A61K2800/652 , A61K2800/654 , A61Q17/04 , Y10S514/937
摘要： The present invention provides, as a first aspect, a sun protection agent, which is especially suitable for use in pharmaceutical or cosmetic applications, comprising a) a micronized organic UV absorber; and one, or preferably both of; b) an oil-soluble, non-micronized UV absorber and/or an inorganic micropigment; and c) a polymeric hollow sphere additive and/or a polymer selected from xanthan and/or polyvinylpyrrolidone. The present invention also provides a sunscreen composition comprising A) 0.1 to 15%, preferably 0.5 to 10% by weight, based on the total composition of a sun screen agent according to the present invention; and B) a cosmetically acceptable carrier.
摘要翻译：作为第一方面，本发明提供了特别适用于药物或化妆品应用的防晒剂，其包括：a）微粉化有机UV吸收剂; 和b）油溶性非微粉化紫外线吸收剂和/或无机微胶囊中的一种，或优选两者; 和c）聚合物中空球体添加剂和/或选自黄原胶和/或聚乙烯吡咯烷酮的聚合物。本发明还提供防晒组合物，其包含A）基于总组合物的0.1至15重量％，优选0.5至10重量％根据本发明的防晒剂; 和B）美容上可接受的载体。

10. 发明授权

US08361446B2 Use of benzotriazole derivatives for photostabilisation 有权
标题翻译：苯并三唑衍生物用于光稳定化
公开(公告)号：US08361446B2
公开(公告)日：2013-01-29
申请号：US11919104
申请日：2006-04-20
申请人： Stefan Müller , Jochen Giesinger , Thomas Ehlis , Bernd Herzog , Peter König , Gilbert Kreyer , Katja Quass
发明人： Stefan Müller , Jochen Giesinger , Thomas Ehlis , Bernd Herzog , Peter König , Gilbert Kreyer , Katja Quass
IPC分类号： A61K8/49 , A61P17/04
CPC分类号： A61Q17/04 , A61K8/496 , A61K2800/52
摘要： Use of benzotriazole derivatives of formula (1), wherein R1 is C1-C30alkyl; C1C5alkoxy; C1-C5alkoxycarbonyl; C5-C7cycloalkyl; C6-C10aryl; aralkyl; —SO3M; a radical of formula (1a) R3 is hydrogen; C1C5alkyl; C1C5alkoxy; halogen, preferably Cl; or hydroxy; R4 and R5 are each independently of the other hydrogen; or d-C5alkyl; m is 1 or 2; n is O or 1; if m=1, R2 is hydrogen; unsubstituted or phenyl-substituted d-C1-C12alkyl; or C6-C10aryl; if m=2, R2 is the direct bond; or —(CH2)p—; and p is 1 to 3; for enhancing the photostability of cosmetic or dermatologic compositions comprising at least one further organic UV absorber.
摘要翻译：式（1）的苯并三唑衍生物的用途，其中R 1是C 1 -C 30烷基; C1C5烷氧基 C1-C5烷氧基羰基; C5-C7环烷基; C6-C10芳基; 芳烷基 -SO3M; 式（1a）的基团R 3是氢; C 1 -C 5烷基; C1C5烷氧基卤素，优选Cl; 或羟基; R4和R5各自独立地为氢; 或d-C 5烷基; m为1或2; n为0或1; 如果m = 1，则R2为氢; 未取代或苯基取代的d-C 1 -C 12烷基; 或C 6 -C 10芳基; 如果m = 2，则R2是直接键; 或 - （CH 2）p - ; p为1〜3; 用于增强包含至少一种另外的有机UV吸收剂的化妆品或皮肤病学组合物的光稳定性。

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