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1. 发明申请

WO2008070680A1 SEPARATION OF HIGH DENSITY LIPOPROTEINS ON POLYMER MONOLITHS WITH DECREASED HYDROPHOBICITY 审中-公开
标题翻译：高密度脂蛋白在聚合物单体上的分离与降低的疏水性
公开(公告)号：WO2008070680A1
公开(公告)日：2008-06-12
申请号：PCT/US2007/086408
申请日：2007-12-04
申请人： BERKELEY HEARTLAB, INC , WARNICK, George, Russell , HEWETT, Gary
发明人： WARNICK, George, Russell , HEWETT, Gary
IPC分类号： B01D15/08
CPC分类号： B01J20/26 , B01J20/261 , B01J20/264 , B01J20/267 , B01J20/28042 , B01J20/285 , B01J2220/82
摘要： Described are polymer monolith compositions for separating high density lipoprotein, as well as related methods of use.
摘要翻译：描述了用于分离高密度脂蛋白的聚合物整料组合物以及相关的使用方法。

2. 发明申请

WO2007092380A2 APOLIPOPROTEIN E GENOTYPING AND ACCOMPANYING INTERNET-BASED HEALTH MANAGEMENT SYSTEM 审中-公开
标题翻译： APOLIPOPROTEIN E基因分析和相关互联网卫生管理系统
公开(公告)号：WO2007092380A2
公开(公告)日：2007-08-16
申请号：PCT/US2007003034
申请日：2007-02-06
申请人： BERKELEY HEARTLAB INC , BANET MATTHEW , SCHULTZ RANDON , DHILLON MARSHAL , FLEMING ADAM , VISSER HENK , HALL CHRISTOPHER , LANIER VANCE JR
发明人： BANET MATTHEW , SCHULTZ RANDON , DHILLON MARSHAL , FLEMING ADAM , VISSER HENK , HALL CHRISTOPHER , LANIER VANCE JR
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , G06F19/18 , G06F19/3418 , G06F19/3475 , G06F19/3481
摘要： The invention provides a system for monitoring a patient that includes: 1) a blood test that measures an Apo E genotype or a derivative thereof from the patient to generate Apo E information; 2) a database that receives and stores the patient's Apo E information; and 3) an Internet-based system connected to the database and configured to process the Apo E information with an algorithm that, in response, generates a diet and treatment plan for the patient
摘要翻译：本发明提供一种用于监测患者的系统，其包括：1）测量来自患者的Apo E基因型或其衍生物的血液检测以产生Apo E信息; 2）接收并存储患者Apo E信息的数据库; 以及3）连接到数据库并基于因特网的系统，其被配置为使用算法来处理Apo E信息，所述算法作为响应，为患者产生饮食和治疗计划

3. 发明专利

AU1814301A Cardiovascular healthcare management system and method 未知
公开(公告)号：AU1814301A
公开(公告)日：2001-06-12
申请号：AU1814301
申请日：2000-12-01
申请人： BERKELEY HEARTLAB INC
发明人： RUDERMAN FRANK R , SHEWMAKE DAVID T
IPC分类号： G16H10/60 , G06F19/00
摘要： The disclosure relates to an interactive, web based cardiovascular healthcare management system which has an infomediary site with databases having information relating to cardiovascular disease risk factors such as age, blood pressure, LDL, HDL and subfractions thereof and cardiovascular disease management such as diet, exercise, drugs and cardiovascular education materials. The physician can communicate electronically with the infomediary site to obtain patient test results and formulate a patient treatment plan from the diet, exercise and drug data. The physician can electronically communicate treatment plans to the patient through a record in the infomediary site. The patient can electronically communicate compliance information to the physician through the patient record. The infomediary site may also provide a case manager to provide initial draft treatment plans to the physician, gather patient history data and/or patient treatment plan compliance data.

4. 发明专利

AU2003221918A1 A METHOD FOR IDENTIFYING AT RISK CARDIOVASCULAR DISEASE PATIENTS 未知
公开(公告)号：AU2003221918A1
公开(公告)日：2003-10-27
申请号：AU2003221918
申请日：2003-04-11
申请人： BERKELEY HEARTLAB INC
发明人： SHEWMAKE DAVID , RUDERMAN FRANK , BOGGESS CHRISTOPHER , CLENDENEN FAITH
IPC分类号： G01N33/92 , G01N24/00

5. 发明申请

US20040043496A1 Method for identifying patients who will require multiple invasive cardiovascular procedures 审中-公开
标题翻译：确定需要多次侵入性心血管手术的患者的方法
公开(公告)号：US20040043496A1
公开(公告)日：2004-03-04
申请号：US10463664
申请日：2003-06-16
申请人： Berkeley HeartLab, Inc.
发明人： H. Robert Superko
IPC分类号： G01N033/92
CPC分类号： G01N33/92 , G01N2800/52
摘要： The invention provides a method for identifying patients who will require multiple invasive cardiac procedures comprising measuring elevated LDL IVb levels in patients who have had or will have invasive heart surgery.
摘要翻译：本发明提供了一种用于鉴定需要多次侵入性心脏手术的患者的方法，包括测量已经或将要进行侵入性心脏手术的患者的升高的LDL IVb水平。

6. 发明申请

WO2007040975A3 INTERNET-BASED PATIENT-MONITORING SYSTEM FEATURING INTERACTIVE MESSAGING ENGINE 审中-公开
公开(公告)号：WO2007040975A3
公开(公告)日：2007-04-12
申请号：PCT/US2006/036311
申请日：2006-09-18
申请人： BERKELEY HEARTLAB, INC. , HALL, Christopher , LANIER, Vance, Whitson, Jr. , BANET, Matthew , SCHULTZ, Randon , DHILLON, Marshal , FLEMING, Adam , VISSER, Henk
发明人： HALL, Christopher , LANIER, Vance, Whitson, Jr. , BANET, Matthew , SCHULTZ, Randon , DHILLON, Marshal , FLEMING, Adam , VISSER, Henk
IPC分类号： A61B5/00
摘要： The invention provides: 1) a monitoring device featuring systems that monitor the patient's vital sign and exercise information; 2) an Internet-based system configured to receive, store, and display vital sign and exercise from the monitoring device, and blood test information from an external blood test; and 3) a messaging system configured to process the vital sign, exercise, and blood test information, and in response send a personalized message to the patient.

7. 发明申请

WO2003087844A1 A METHOD FOR IDENTIFYING AT RISK CARDIOVASCULAR DISEASE PATIENTS 审中-公开
标题翻译：一种识别风险性心脏病患者的方法
公开(公告)号：WO2003087844A1
公开(公告)日：2003-10-23
申请号：PCT/US2003/011375
申请日：2003-04-11
申请人： BERKELEY HEARTLAB, INC. , SHEWMAKE, David , RUDERMAN, Frank , BOGGESS, Christopher , CLENDENEN, Faith
发明人： SHEWMAKE, David , RUDERMAN, Frank , BOGGESS, Christopher , CLENDENEN, Faith
IPC分类号： G01N33/92
CPC分类号： G01N33/92 , G01N2800/32 , G01N2800/52
摘要： The invention provides a data base of LDL, I, IIa, IIb, IIIa, IIb, IVa, IVb and HDL2a, HDL2b, HDL 3a, HDL 3b and HDL 3c together with patient data such as HDL-C, LDL-C, Apo A, ApoB, Lp(a) and patient personal data useful for treatment, diagnosing, and monitoring cardiovascular disease. The data base contains the LDL and HDL subfraction data in quantitative mg/dl values and permits deriving relationship amongst the LDL and HDL values and cardiovascular disease. Quantitative data permits more effective treatment and monitoring of cardiovascular disease. For example, quantitative differences in LDL and HDL subclass levels can determine the need for more or less aggressive treatment. The data base which includes patient events, procedures, interventions which is correlated to LDL and HDl quantitative subclass data permits development of personalized patient treatment plans and monitoring the effectiveness of such treatment. Thus, LDL and HDL quantitative subfraction data can be used to more effectively treat and monitor cardiovascular disease. The invention, for example, provides a method for identifying patients with normal NCEP lipid levels who are in need of treatment for cardiovascular disease comprising measuring one or more LDL or HDL particle subclass levels and identifying abnormal LDL or HDL subclass levels. LDL III a & b and HDL 2b are preferred subclasses.
摘要翻译：本发明提供LDL，I，IIa，IIb，IIIa，IIb，IVa，IVb和HDL2a，HDL2b，HDL 3a，HDL 3b和HDL 3c的数据库以及患者数据如HDL-C，LDL-C，Apo A，ApoB，Lp（a）和患者个人资料可用于治疗，诊断和监测心血管疾病。数据库包含定量mg / dl值中的LDL和HDL次级分数据，并允许LDL和HDL值与心血管疾病之间的关系。定量数据可以更有效地治疗和监测心血管疾病。例如，LDL和HDL亚类水平的定量差异可以确定对或多或少积极治疗的需要。包括与LDL和HDI定量亚类数据相关的患者事件，程序，干预措施的数据库允许开发个性化的患者治疗计划并监测此类治疗的有效性。因此，LDL和HDL定量分数据可用于更有效地治疗和监测心血管疾病。例如，本发明提供了一种用于鉴定需要治疗心血管疾病的正常NCEP脂质水平的患者的方法，包括测量一种或多种LDL或HDL颗粒亚类水平并鉴定异常的LDL或HDL亚类水平。 LDL III a＆b和HDL 2b是优选的亚类。

8. 发明申请

US20030235918A1 Method for identifying at risk cardiovascular disease patients 有权
标题翻译：识别危险心血管疾病患者的方法
公开(公告)号：US20030235918A1
公开(公告)日：2003-12-25
申请号：US10412838
申请日：2003-04-12
申请人： Berkeley HeartLab, Inc.
发明人： David Shewmake , Frank Ruderman , Christopher Boggess , Faith Clendenen
IPC分类号： G01N031/00
CPC分类号： G01N33/92 , C25B1/285 , G01N2800/32 , G01N2800/52 , Y10T436/104165
摘要： The invention provides a data base of LDL, I, Ia, IIb, IIIa, IIb, IVa, IVb and HDL2a, HDL2b, HDL 3a, HDL 3b and HDL 3c together with patient data such as HDL-C, LDL-C, Apo A, ApoB, Lp(a) and patient personal data useful for treatment, diagnosing, and monitoring cardiovascular disease. The data base contains the LDL and HDL subfraction data in quantitative mg/dl values and permits deriving relationship amongst the LDL and HDL values and cardiovascular disease. Quantitative data permits more effective treatment and monitoring of cardiovascular disease. For example, quantitative differences in LDL and HDL subclass levels can determine the need for more or less aggressive treatment. The data base which includes patient events, procedures, interventions which is correlated to LDL and HD1 quantitative subclass data permits development of personalized patient treatment plans and monitoring the effectiveness of such treatment. Thus, LDL and HDL quantitative subfraction data can be used to more effectively treat and monitor cardiovascular disease. The invention, for example, provides a method for identifying patients with normal NCEP lipid levels who are in need of treatment for cardiovascular disease comprising measuring one or more LDL or HDL particle subclass levels and identifying abnormal LDL or HDL subclass levels. LDL III a & b and HDL 2b are preferred subclasses.
摘要翻译：本发明提供LDL，I，Ia，IIb，IIIa，IIb，IVa，IVb和HDL2a，HDL2b，HDL 3a，HDL 3b和HDL 3c的数据库以及患者数据如HDL-C，LDL-C，Apo A，ApoB，Lp（a）和患者个人资料可用于治疗，诊断和监测心血管疾病。数据库包含定量mg / dl值中的LDL和HDL次级分数据，并允许LDL和HDL值与心血管疾病之间的关系。定量数据可以更有效地治疗和监测心血管疾病。例如，LDL和HDL亚类水平的定量差异可以确定对或多或少积极治疗的需要。包括与LDL和HD1定量亚类数据相关的患者事件，程序，干预措施的数据库允许开发个性化的患者治疗计划并监测此类治疗的有效性。因此，LDL和HDL定量分数据可用于更有效地治疗和监测心血管疾病。例如，本发明提供了一种用于鉴定需要治疗心血管疾病的正常NCEP脂质水平的患者的方法，包括测量一种或多种LDL或HDL颗粒亚类水平并鉴定异常的LDL或HDL亚类水平。 LDL III a＆b和HDL 2b是优选的亚类。

9. 发明申请

US20030194812A1 Method for identifying risk cardiovascular disease patients 有权
标题翻译：识别风险心血管疾病患者的方法
公开(公告)号：US20030194812A1
公开(公告)日：2003-10-16
申请号：US10122081
申请日：2002-04-12
申请人： Berkeley HeartLab, Inc.
发明人： David Shewmake , Frank Ruderman , Christopher Boggess
IPC分类号： G01N033/92
CPC分类号： G01N33/92 , G01N2800/32 , G01N2800/52
摘要： The invention provides a method for identifying patients with normal NCEP lipid levels who are in need of treatment for cardiovascular disease comprising measuring one or more LDL or HDL particle subclass levels and identifying abnormal LDL or HDL subclass levels. LDL III anullb and HDL 2b are preferred subclasses.
摘要翻译：本发明提供了一种用于鉴定需要治疗心血管疾病的正常NCEP脂质水平的患者的方法，包括测量一种或多种LDL或HDL颗粒亚类水平并鉴定异常的LDL或HDL亚类水平。 LDL III a + b和HDL 2b是优选的亚类。

10. 发明申请

WO2007040963A3 INTERNET-BASED SYSTEM FOR MONITORING BLOOD TEST, VITAL SIGN, AND EXERCISE INFORMATION FROM A PATIENT 审中-公开
标题翻译：基于互联网的系统，用于监测血液测试，VITAL标志和来自患者的锻炼信息
公开(公告)号：WO2007040963A3
公开(公告)日：2007-10-25
申请号：PCT/US2006036212
申请日：2006-09-18
申请人： BERKELEY HEARTLAB INC , HALL CHRISTOPER , LANIER VANCE WHITSON JR , SHEWMAKE DAVID , RUDERMAN FRANK , BANET MATTHEW , SCHULTZ RANDON , DHILLON MARSHAL , FLEMING ADAM , VISSER HENK
发明人： HALL CHRISTOPER , LANIER VANCE WHITSON JR , SHEWMAKE DAVID , RUDERMAN FRANK , BANET MATTHEW , SCHULTZ RANDON , DHILLON MARSHAL , FLEMING ADAM , VISSER HENK
IPC分类号： G06Q10/00
CPC分类号： G06F19/3418 , G06F19/3456 , G06F19/3475 , G16H10/60 , G16H15/00 , G16H40/63 , G16H50/20
摘要： The invention provides a system for monitoring a patient that includes: 1) a first database that stores the patient's blood test information; 2) a monitoring device that collects the patient's cardiovascular and exercise information; 3) a second database that receives cardiovascular and exercise information from the monitoring device; and 4) an Internet-based system that displays the blood test, cardiovascular, and exercise information.
摘要翻译：本发明提供了一种用于监测患者的系统，包括：1）存储患者血液测试信息的第一数据库; 2）收集患者心血管和运动信息的监测装置; 3）从监测装置接收心血管和运动信息的第二数据库; 以及4）基于互联网的系统，显示血液测试，心血管和运动信息。

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