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1. 发明申请

WO2008109603A2 VITAL SIGN MONITOR FOR CUFFLESSLY MEASURING BLOOD PRESSURE WITHOUT USING AN EXTERNAL CALIBRATION 审中-公开
标题翻译：无需使用外部校准即可测量血压的VITAL SIGN MONITOR
公开(公告)号：WO2008109603A2
公开(公告)日：2008-09-12
申请号：PCT/US2008/055803
申请日：2008-03-04
申请人： TRIAGE WIRELESS, INC. , ZHOU, Zhou , DHILLON, Marshall, Singh , VISSER, Henk , TERRY, Andrew, Stanley , BANET, Matthew
发明人： ZHOU, Zhou , DHILLON, Marshall, Singh , VISSER, Henk , TERRY, Andrew, Stanley , BANET, Matthew
IPC分类号： A61B5/021
CPC分类号： A61B5/021 , A61B5/02125 , A61B5/0261 , A61B5/0402 , A61B5/6824 , A61B5/7239
摘要： The invention provides a method for measuring a patient's blood pressure featuring the following steps: 1) measuring a first time-dependent optical signal with a first optical sensor; 2) measuring a second time-dependent optical signal with a second optical sensor; 3) measuring a time-dependent electrical signal with an electrical sensor; 4) estimating the patient's arterial properties using either the first or second time-dependent optical signal; 5) determining a pulse transit time (PTT) from the time-dependent electrical signal and at least one of the first and second time-dependent optical signals; and 6) calculating a blood pressure value using a mathematical model that includes the PTT and the patient's arterial properties.
摘要翻译：本发明提供了一种用于测量患者血压的方法，其特征在于以下步骤：1）用第一光学传感器测量第一时间相关的光信号; 2）用第二光学传感器测量第二时间相关光信号; 3）用电传感器测量与时间有关的电信号; 4）使用第一或第二时间依赖光信号估计患者的动脉特性; 5）根据时间相关电信号和第一和第二时间依赖光信号中的至少一个确定脉冲传播时间（PTT）; 以及6）使用包括PTT和患者动脉特性的数学模型来计算血压值。

2. 发明申请

WO2007040975A3 INTERNET-BASED PATIENT-MONITORING SYSTEM FEATURING INTERACTIVE MESSAGING ENGINE 审中-公开
公开(公告)号：WO2007040975A3
公开(公告)日：2007-04-12
申请号：PCT/US2006/036311
申请日：2006-09-18
申请人： BERKELEY HEARTLAB, INC. , HALL, Christopher , LANIER, Vance, Whitson, Jr. , BANET, Matthew , SCHULTZ, Randon , DHILLON, Marshal , FLEMING, Adam , VISSER, Henk
发明人： HALL, Christopher , LANIER, Vance, Whitson, Jr. , BANET, Matthew , SCHULTZ, Randon , DHILLON, Marshal , FLEMING, Adam , VISSER, Henk
IPC分类号： A61B5/00
摘要： The invention provides: 1) a monitoring device featuring systems that monitor the patient's vital sign and exercise information; 2) an Internet-based system configured to receive, store, and display vital sign and exercise from the monitoring device, and blood test information from an external blood test; and 3) a messaging system configured to process the vital sign, exercise, and blood test information, and in response send a personalized message to the patient.

3. 发明申请

WO2007040971A2 INTERNET-BASED HEALTH MANAGEMENT SYSTEM FOR IDENTIFYING AND MINIMIZING RISK FACTORS CONTRIBUTING TO METABOLIC SYNDROME 审中-公开
标题翻译：基于因特网的健康管理系统识别和最小化代谢综合症的风险因素
公开(公告)号：WO2007040971A2
公开(公告)日：2007-04-12
申请号：PCT/US2006/036301
申请日：2006-09-18
申请人： BERKELEY HEARTLAB , HALL, Christopher , LANIER, Vance , SHEWMAKE, David , RUDERMAN, Frank , BANET, Matthew , SCHULTZ, Randon , DHILLON, Marshal , FLEMING, Adam , VISSER, Henk
发明人： HALL, Christopher , LANIER, Vance , SHEWMAKE, David , RUDERMAN, Frank , BANET, Matthew , SCHULTZ, Randon , DHILLON, Marshal , FLEMING, Adam , VISSER, Henk
IPC分类号： G01N33/92
CPC分类号： A61B5/0022 , A61B5/021 , A61B5/024 , A61B5/145 , A61B5/14532 , G06F19/00 , G06F19/3481 , G06Q50/22 , G16H10/20 , G16H10/60 , G16H15/00
摘要： The invention provides a system that determines if a patient has Metabolic Syndrome, and in response provides a disease-management program that helps reduce medical risks associated with this malady. The system features a device configured to collect glucose information and blood pressure information, and then transmit this information to a central computer system. The system also includes a database configured to receive triglyceride information and cholesterol information from an external blood test, and a central computer system featuring: 1) a communication interface configured to communicate with the device to receive glucose and blood pressure information and with the database to receive triglyceride and cholesterol information; 2) a user interface configured to accept patient information; and 3) a processor configured to operate an algorithm that processes the glucose, blood pressure, triglyceride, cholesterol, and patient information to determine if the patient has Metabolic Syndrome.
摘要翻译：本发明提供了一种确定患者是否患有代谢综合征并且作为响应提供疾病管理程序以帮助降低与这种疾病相关的医疗风险的系统。该系统具有一个配置为收集葡萄糖信息和血压信息的设备，然后将该信息传输到中央计算机系统。该系统还包括配置成从外部血液测试接收甘油三酯信息和胆固醇信息的数据库，以及中央计算机系统，其特征在于：1）通信接口，被配置为与设备通信以接收葡萄糖和血压信息，并且与数据库接收甘油三酯和胆固醇信息; 2）配置成接受患者信息的用户界面; 以及3）配置成操作处理葡萄糖，血压，甘油三酯，胆固醇和患者信息以确定患者是否患有代谢综合征的算法的处理器。

4. 发明申请

WO2008154643A1 VITAL SIGN MONITOR FOR MEASURING BLOOD PRESSURE USING OPTICAL, ELECTRICAL, AND PRESSURE WAVEFORMS 审中-公开
标题翻译：使用光学，电气和压力波形测量血压的VITAL SIGN MONITOR
公开(公告)号：WO2008154643A1
公开(公告)日：2008-12-18
申请号：PCT/US2008/066769
申请日：2008-06-12
申请人： TRIAGE WIRELESS, INC. , BANET, Matthew, John , ZHOU, Zhou , MARSHAL, Dhillon, Singh , KOPOTIC, Robert, J.
发明人： BANET, Matthew, John , ZHOU, Zhou , MARSHAL, Dhillon, Singh , KOPOTIC, Robert, J.
IPC分类号： A61B5/00
CPC分类号： A61B5/02125 , A61B5/0022 , A61B5/02133 , A61B5/0225 , A61B5/02416 , A61B5/0295 , A61B5/0402 , A61B5/0452 , A61B5/1118 , A61B5/14551 , A61B5/6824 , A61B5/721 , A61B5/7239 , A61B5/742
摘要： A method and apparatus for continuous measurement of blood pressure, based on pulse transit time, which does not require any external calibration. This technique, referred to herein as the 'composite technique', is carried out with a body- worn sensor that measures blood pressure and other vital signs, and wirelessly transmits them to a remote monitor. A network of disposable sensors, typically placed on the patient's right arm and chest, connect to the body sensor and measure a time-dependent electrical waveform, optical waveform, and pressure waveform. The disposable sensors typically include an armband that features an inflatable bladder coupled to a pressure sensor, at least 3 electrical sensors (e.g. electrodes), and an optical sensor (e.g., a light source and photodiode) attached to a wrist-worn band.
摘要翻译：基于脉冲传播时间连续测量血压的方法和装置，其不需要任何外部校准。这种技术在本文中被称为“复合技术”，是用身体磨损的传感器进行的，该传感器测量血压和其他生命体征，并将其无线传输到远程监视器。通常放置在患者右臂和胸部的一次性传感器网络连接到身体传感器，并测量与时间有关的电波形，光学波形和压力波形。一次性传感器通常包括臂罩，其具有连接到压力传感器，至少3个电传感器（例如电极）和连接到腕带的光学传感器（例如，光源和光电二极管）的可充气囊。

5. 发明申请

WO2007092380A2 APOLIPOPROTEIN E GENOTYPING AND ACCOMPANYING INTERNET-BASED HEALTH MANAGEMENT SYSTEM 审中-公开
标题翻译： APOLIPOPROTEIN E基因分析和相关互联网卫生管理系统
公开(公告)号：WO2007092380A2
公开(公告)日：2007-08-16
申请号：PCT/US2007003034
申请日：2007-02-06
申请人： BERKELEY HEARTLAB INC , BANET MATTHEW , SCHULTZ RANDON , DHILLON MARSHAL , FLEMING ADAM , VISSER HENK , HALL CHRISTOPHER , LANIER VANCE JR
发明人： BANET MATTHEW , SCHULTZ RANDON , DHILLON MARSHAL , FLEMING ADAM , VISSER HENK , HALL CHRISTOPHER , LANIER VANCE JR
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , G06F19/18 , G06F19/3418 , G06F19/3475 , G06F19/3481
摘要： The invention provides a system for monitoring a patient that includes: 1) a blood test that measures an Apo E genotype or a derivative thereof from the patient to generate Apo E information; 2) a database that receives and stores the patient's Apo E information; and 3) an Internet-based system connected to the database and configured to process the Apo E information with an algorithm that, in response, generates a diet and treatment plan for the patient
摘要翻译：本发明提供一种用于监测患者的系统，其包括：1）测量来自患者的Apo E基因型或其衍生物的血液检测以产生Apo E信息; 2）接收并存储患者Apo E信息的数据库; 以及3）连接到数据库并基于因特网的系统，其被配置为使用算法来处理Apo E信息，所述算法作为响应，为患者产生饮食和治疗计划

6. 发明申请

WO2007040961A3 MONITORING DEVICE FOR MEASURING CALORIE EXPENDITURE 审中-公开
标题翻译：监测卡路里支出的监测装置
公开(公告)号：WO2007040961A3
公开(公告)日：2007-07-19
申请号：PCT/US2006036174
申请日：2006-09-18
申请人： BERKELEY HEARTLAB , BROWNING RAY , HALL CHRISTOPHER , BANET MATTHEW
发明人： BROWNING RAY , HALL CHRISTOPHER , BANET MATTHEW
IPC分类号： A61B5/00
CPC分类号： A61B5/002 , A61B5/0022 , A61B5/024 , A61B5/11
摘要： The invention provides a monitoring device that features: 1) a cardiac sensor component with at least one light-emitting diode and a photodetector; 2) a pedometer component with at least one motion-sensing component (e.g., an accelerometer); and 3) a wireless component with a wireless interface that communicates with an external weight scale. The device also features a microprocessor in electrical communication with the cardiac sensor, pedometer, and wireless components and configured to analyze: 1) a signal from the cardiac sensor component to generate heart rate information; 2) a signal from the pedometer component to generate exercise information; 3) heart rate and exercise information to generate calorie information; and 4) a signal from the external weight scale to calculate weight information (e.g., weight and percent body fat).
摘要翻译：本发明提供了一种监测装置，其特征在于：1）具有至少一个发光二极管和光电检测器的心脏传感器部件; 2）具有至少一个运动感测部件（例如，加速度计）的计步器部件; 以及3）具有与外部重量秤通信的无线接口的无线部件。该装置还具有与心脏传感器，计步器和无线部件电通信的微处理器，并且被配置为分析：1）来自心脏传感器部件的信号以产生心率信息; 2）来自计步器组件的信号以产生运动信息; 3）心率和运动信息产生卡路里信息; 和4）来自外部重量级的信号以计算重量信息（例如体重和身体脂肪百分比）。

7. 发明申请

WO2009009761A1 DEVICE FOR DETERMINING RESPIRATORY RATE AND OTHER VITAL SIGNS 审中-公开
标题翻译：用于确定呼吸率和其他身体信号的装置
公开(公告)号：WO2009009761A1
公开(公告)日：2009-01-15
申请号：PCT/US2008/069862
申请日：2008-07-11
申请人： TRIAGE WIRELESS, INC. , BANET, Matthew, J. , ZHOU, Zhou , KOPOTIC, Robert, J. , DHILLON, Marshall, Singh , TERRY, Andrew, Stanley , VISSER, Henk, II
发明人： BANET, Matthew, J. , ZHOU, Zhou , KOPOTIC, Robert, J. , DHILLON, Marshall, Singh , TERRY, Andrew, Stanley , VISSER, Henk, II
IPC分类号： A61B5/08
CPC分类号： A61B5/0816 , A61B5/002 , A61B5/0022 , A61B5/02055 , A61B5/022 , A61B5/0408 , A61B5/0823 , A61B5/1455 , A61B5/6826 , A61B5/6838 , A61B5/7225 , A61B5/7257 , A61B5/726 , A61B7/04 , A61B2560/0412 , A61B2560/0462 , A61B2560/0468 , G06F19/00 , G16H40/67
摘要： A body-worn sensor that measures respiratory rate and other vital signs using an acoustic sensor (e.g., a small-scale sensor). The body-worn sensor features a chest-worn patch sensor that combines both the acoustic sensor and an ECG electrode into a single adhesive patch. To measure blood pressure, the device additionally performs a 'composite' PTT-based measurement that features both pressure- dependent and pressure-free measurements. The acoustic sensor measures respiration rate by recording sounds related to the patient's inspiration and expiration. The acoustic sensor is typically placed near the patient's trachea, but can also be placed on the middle right and left side of the chest, and the middle right and left side of the back.
摘要翻译：使用声传感器（例如小型传感器）测量呼吸频率和其他生命体征的身体磨损传感器。身体磨损的传感器具有胸部贴片传感器，其将声学传感器和ECG电极组合成单个粘合剂贴片。为了测量血压，该装置还执行基于PTT的“复合”测量，其具有压力依赖性和无压力测量。声学传感器通过记录与患者的吸气和呼气相关的声音来测量呼吸率。声学传感器通常放置在病人的气管附近，但也可以放置在胸部的中间右侧和左侧以及背部的中间右侧和左侧。

8. 发明申请

WO2007040971A3 INTERNET-BASED HEALTH MANAGEMENT SYSTEM FOR IDENTIFYING AND MINIMIZING RISK FACTORS CONTRIBUTING TO METABOLIC SYNDROME 审中-公开
标题翻译：基于互联网的卫生管理系统，用于识别和最小化风险因素对代谢综合征的贡献
公开(公告)号：WO2007040971A3
公开(公告)日：2007-10-11
申请号：PCT/US2006036301
申请日：2006-09-18
申请人： BERKELEY HEARTLAB , HALL CHRISTOPHER , LANIER VANCE , SHEWMAKE DAVID , RUDERMAN FRANK , BANET MATTHEW , SCHULTZ RANDON , DHILLON MARSHAL , FLEMING ADAM , VISSER HENK
发明人： HALL CHRISTOPHER , LANIER VANCE , SHEWMAKE DAVID , RUDERMAN FRANK , BANET MATTHEW , SCHULTZ RANDON , DHILLON MARSHAL , FLEMING ADAM , VISSER HENK
IPC分类号： G06F19/00
CPC分类号： A61B5/0022 , A61B5/021 , A61B5/024 , A61B5/145 , A61B5/14532 , G06F19/3481 , G06Q50/22 , G16H10/20 , G16H10/60 , G16H15/00
摘要： The invention provides a system that determines if a patient has Metabolic Syndrome, and in response provides a disease-management program that helps reduce medical risks associated with this malady. The system features a device configured to collect glucose information and blood pressure information, and then transmit this information to a central computer system. The system also includes a database configured to receive triglyceride information and cholesterol information from an external blood test, and a central computer system featuring: 1) a communication interface configured to communicate with the device to receive glucose and blood pressure information and with the database to receive triglyceride and cholesterol information; 2) a user interface configured to accept patient information; and 3) a processor configured to operate an algorithm that processes the glucose, blood pressure, triglyceride, cholesterol, and patient information to determine if the patient has Metabolic Syndrome.
摘要翻译：本发明提供了一种确定患者是否具有代谢综合征的系统，并且作为响应提供了有助于减少与该疾病相关的医疗风险的疾病管理程序。该系统具有被配置为收集葡萄糖信息和血压信息的装置，然后将该信息发送到中央计算机系统。该系统还包括配置为从外部血液测试中接收甘油三酯信息和胆固醇信息的数据库，以及中央计算机系统，其特征在于：1）通信接口，被配置为与设备通信以接收葡萄糖和血压信息，并且与数据库接受甘油三酯和胆固醇信息; 2）被配置为接收患者信息的用户界面; 以及3）处理器，其被配置为操作处理葡萄糖，血压，甘油三酯，胆固醇和患者信息以确定患者是否具有代谢综合征的算法。

9. 发明申请

WO2007040961A2 MONITORING DEVICE FOR MEASURING CALORIE EXPENDITURE 审中-公开
标题翻译：监测卡路里开支的监测装置
公开(公告)号：WO2007040961A2
公开(公告)日：2007-04-12
申请号：PCT/US2006/036174
申请日：2006-09-18
申请人： BERKELEY HEARTLAB , BROWNING, Ray , HALL, Christopher , BANET, Matthew
发明人： BROWNING, Ray , HALL, Christopher , BANET, Matthew
IPC分类号： A61B5/04
CPC分类号： A61B5/002 , A61B5/0022 , A61B5/024 , A61B5/11 , G06F19/00 , G16H40/67
摘要： The invention provides a monitoring device that features: 1) a cardiac sensor component with at least one light-emitting diode and a photodetector; 2) a pedometer component with at least one motion-sensing component (e.g., an accelerometer); and 3) a wireless component with a wireless interface that communicates with an external weight scale. The device also features a microprocessor in electrical communication with the cardiac sensor, pedometer, and wireless components and configured to analyze: 1) a signal from the cardiac sensor component to generate heart rate information; 2) a signal from the pedometer component to generate exercise information; 3) heart rate and exercise information to generate calorie information; and 4) a signal from the external weight scale to calculate weight information (e.g., weight and percent body fat).
摘要翻译：本发明提供了一种监测装置，其特征在于：1）具有至少一个发光二极管和光电探测器的心脏传感器部件; 2）具有至少一个运动感测部件（例如，加速计）的计步器部件; 以及3）具有与外部体重秤进行通信的无线接口的无线组件。该装置还具有与心脏传感器，计步器和无线组件电通信的微处理器，并被配置为分析：1）来自心脏传感器组件的信号以生成心率信息; 2）来自计步器组件的信号以生成锻炼信息; 3）心率和运动信息来生成卡路里信息; 和4）来自外部体重秤的信号，以计算体重信息（例如，体重和身体脂肪百分比）。

10. 发明申请

WO2008109603A3 VITAL SIGN MONITOR FOR CUFFLESSLY MEASURING BLOOD PRESSURE WITHOUT USING AN EXTERNAL CALIBRATION 审中-公开
标题翻译：无需使用外部校准即可测量血压的VITAL SIGN监视器
公开(公告)号：WO2008109603A3
公开(公告)日：2009-12-30
申请号：PCT/US2008055803
申请日：2008-03-04
申请人： TRIAGE WIRELESS INC , ZHOU ZHOU , DHILLON MARSHALL SINGH , VISSER HENK , TERRY ANDREW STANLEY , BANET MATTHEW
发明人： ZHOU ZHOU , DHILLON MARSHALL SINGH , VISSER HENK , TERRY ANDREW STANLEY , BANET MATTHEW
IPC分类号： A61B5/02
CPC分类号： A61B5/021 , A61B5/02125 , A61B5/0261 , A61B5/0402 , A61B5/6824 , A61B5/7239
摘要： The invention provides a method for measuring a patient's blood pressure featuring the following steps: 1) measuring a first time-dependent optical signal with a first optical sensor; 2) measuring a second time-dependent optical signal with a second optical sensor; 3) measuring a time-dependent electrical signal with an electrical sensor; 4) estimating the patient's arterial properties using either the first or second time-dependent optical signal; 5) determining a pulse transit time (PTT) from the time-dependent electrical signal and at least one of the first and second time-dependent optical signals; and 6) calculating a blood pressure value using a mathematical model that includes the PTT and the patient's arterial properties.
摘要翻译：本发明提供了一种用于测量患者血压的方法，其特征在于以下步骤：1）用第一光学传感器测量第一时间相关的光信号; 2）用第二光学传感器测量第二时间相关光信号; 3）用电传感器测量与时间有关的电信号; 4）使用第一或第二时间依赖光信号估计患者的动脉特性; 5）根据时间相关电信号和第一和第二时间依赖光信号中的至少一个确定脉冲传输时间（PTT）; 以及6）使用包括PTT和患者动脉特性的数学模型来计算血压值。

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