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1. 发明专利

AU3678100A Biosensor 未知
公开(公告)号：AU3678100A
公开(公告)日：2000-11-02
申请号：AU3678100
申请日：2000-04-13
申请人： HITOSHI MUGURUMA , ATSUNORI HIRATSUKA , ISAO KARUBE
发明人： MUGURUMA HITOSHI , HIRATSUKA ATSUNORI , KARUBE ISAO
IPC分类号： G01N27/327 , C12Q1/00
摘要： A novel high-performance biosensor including a plasma-polymerized film, produced by a simpler method, and applicable to a wide range of fields.

2. 发明授权

US08500981B2 Electrophoresis apparatus and electrophoresis method 有权
标题翻译：电泳仪和电泳法
公开(公告)号：US08500981B2
公开(公告)日：2013-08-06
申请号：US13054271
申请日：2009-07-15
申请人： Koji Sakairi , Satonari Akutsu , Yuji Maruo , Takateru Matsunaga , Yutaka Unuma , Atsunori Hiratsuka , Hideki Kinoshita , Nao Sakaguchi , Kenji Yokoyama
发明人： Koji Sakairi , Satonari Akutsu , Yuji Maruo , Takateru Matsunaga , Yutaka Unuma , Atsunori Hiratsuka , Hideki Kinoshita , Nao Sakaguchi , Kenji Yokoyama
IPC分类号： G01N27/447 , G01N27/453
CPC分类号： G01N27/44773
摘要： An electrophoresis apparatus includes a sample separating section for containing a sample separating medium for separating a sample in a horizontal direction, the sample separating section containing the sample separating medium in such a manner that the sample separating medium has an exposed portion at least one end of a surface of the sample separating medium, the surface being in parallel with the horizontal direction; and medium connecting means for connecting a sample containing medium to the sample separating medium at a connecting region, the sample containing medium containing a sample, and the connecting region satisfying a particular equation. By this, an electrophoresis technique with better accuracy than conventional arts can be provided.
摘要翻译：电泳装置包括样品分离部分，用于容纳用于在水平方向上分离样品的样品分离介质，样品分离部分包含样品分离介质，使得样品分离介质具有暴露部分，至少一端所述样品分离介质的表面与所述水平方向平行; 以及介质连接装置，用于在连接区域连接包含样品的介质到样品分离介质，所述样品包含含有样品的介质和满足特定等式的连接区域。由此，可以提供比现有技术更好的精度的电泳技术。

3. 发明授权

US08449748B2 Sample separation/adsorption appliance 有权
标题翻译：样品分离/吸附装置
公开(公告)号：US08449748B2
公开(公告)日：2013-05-28
申请号：US13001274
申请日：2009-06-01
申请人： Uichi Midorikawa , Takateru Matsunaga , Yuji Maruo , Yutaka Unuma , Atsunori Hiratsuka , Hideki Kinoshita , Kenji Yokoyama
发明人： Uichi Midorikawa , Takateru Matsunaga , Yuji Maruo , Yutaka Unuma , Atsunori Hiratsuka , Hideki Kinoshita , Kenji Yokoyama
IPC分类号： G01N27/447
CPC分类号： G01N27/4473
摘要： A sample separation/adsorption appliance (100) according to one embodiment of the present invention includes: a first buffer solution tank (103) equipped with a first electrode (101) and used for holding a first buffer solution; a second buffer solution tank (104) equipped with a second electrode (102) and used for holding a second buffer solution; a sample separation section (110) that holds a sample separation medium (131) for separating a sample; and a conductive section (120) that holds a conductive medium (133), wherein: the sample separation medium (131) and the conductive medium (133) are in contact with the sample adsorption member (132), respectively, on the opposite sides thereof; an end of the sample separation medium (131) opposite to an end being in contact with the sample adsorption member (132) is connected to an inside of the first buffer solution tank (103); and an end of the conductive medium (133) opposite to an end being in contact with the sample adsorption member (132) is connected to an inside of the second buffer solution tank (104). With this arrangement, a sample separation/adsorption appliance that enables efficient transfer of a sample is offered.
摘要翻译：根据本发明的一个实施方案的样品分离/吸附装置（100）包括：装备有第一电极（101）并用于保持第一缓冲溶液的第一缓冲溶液罐（103）装备有第二电极（102）并用于保持第二缓冲溶液的第二缓冲溶液罐（104）; 样品分离部（110），其保持用于分离样品的样品分离介质（131）以及保持导电介质（133）的导电部（120），其中：所述样品分离介质（131）和所述导电介质（133）分别在所述样品吸附部件（132）的相对侧的; 与第一缓冲溶液罐（103）的内部连接的是与样品吸附部件（132）接触的端部相反的样品分离介质（131）的端部。并且与与样品吸附构件（132）接触的端部相对的导电介质（133）的端部连接到第二缓冲溶液罐（104）的内部。通过这种布置，提供了能够有效地转移样品的样品分离/吸附装置。

4. 发明授权

US08221604B2 Method for controlling substance transfer 有权
标题翻译：物质转移控制方法
公开(公告)号：US08221604B2
公开(公告)日：2012-07-17
申请号：US10533015
申请日：2003-10-28
申请人： Kazuyoshi Yano , Isao Karube , Atsunori Hiratsuka , Shuo-Wen Tsai
发明人： Kazuyoshi Yano , Isao Karube , Atsunori Hiratsuka , Shuo-Wen Tsai
IPC分类号： G01N27/447
CPC分类号： B01D57/02 , G01N27/44773 , G01N27/44791
摘要： Transfer of fluid substances, and/or substances comprised in fluid substances, is controlled by introducing a separation medium, which prevents transfer of the fluid substances, and/or the substances comprised in the fluid substances, to an intermediate cavity connecting a first cavity and a second cavity; and introducing a connection medium to replace the separation medium and thereby start substance transfer to the second cavity. Substance transfer may be readily controlled without relying on mechanical means. Based on the present invention, two-dimensional electrophoretic analysis can be readily implemented on a chip.
摘要翻译：通过引入分离介质来控制流体物质和/或包含在流体物质中的物质，该分离介质防止流体物质和/或包含在流体物质中的物质转移到连接第一空腔和第二腔; 并引入连接介质以更换分离介质，从而开始物质转移到第二腔。可以容易地控制物质转移，而不依赖于机械装置。基于本发明，可以容易地在芯片上实现二维电泳分析。

5. 发明申请

US20110094887A1 SAMPLE SEPARATION/ADSORPTION APPLIANCE 有权
标题翻译：样品分离/吸附装置
公开(公告)号：US20110094887A1
公开(公告)日：2011-04-28
申请号：US13001274
申请日：2009-06-01
申请人： Uichi Midorikawa , Takateru Matsunaga , Yuji Maruo , Yutaka Unuma , Atsunori Hiratsuka , Hideki Kinoshita , Kenji Yokoyama
发明人： Uichi Midorikawa , Takateru Matsunaga , Yuji Maruo , Yutaka Unuma , Atsunori Hiratsuka , Hideki Kinoshita , Kenji Yokoyama
IPC分类号： G01N27/447
CPC分类号： G01N27/4473
摘要： A sample separation/adsorption appliance (100) according to one embodiment of the present invention includes: a first buffer solution tank (103) equipped with a first electrode (101) and used for holding a first buffer solution; a second buffer solution tank (104) equipped with a second electrode (102) and used for holding a second buffer solution; a sample separation section (110) that holds a sample separation medium (131) for separating a sample; and a conductive section (120) that holds a conductive medium (133), wherein: the sample separation medium (131) and the conductive medium (133) are in contact with the sample adsorption member (132), respectively, on the opposite sides thereof; an end of the sample separation medium (131) opposite to an end being in contact with the sample adsorption member (132) is connected to an inside of the first buffer solution tank (103); and an end of the conductive medium (133) opposite to an end being in contact with the sample adsorption member (132) is connected to an inside of the second buffer solution tank (104). With this arrangement, a sample separation/adsorption appliance that enables efficient transfer of a sample is offered.
摘要翻译：根据本发明的一个实施方案的样品分离/吸附装置（100）包括：装备有第一电极（101）并用于保持第一缓冲溶液的第一缓冲溶液罐（103）装备有第二电极（102）并用于保持第二缓冲溶液的第二缓冲溶液罐（104）; 样品分离部（110），其保持用于分离样品的样品分离介质（131）以及保持导电介质（133）的导电部（120），其中：所述样品分离介质（131）和所述导电介质（133）分别在所述样品吸附部件（132）的相对侧的; 与第一缓冲溶液罐（103）的内部连接的是与样品吸附部件（132）接触的端部相反的样品分离介质（131）的端部。并且与与样品吸附构件（132）接触的端部相对的导电介质（133）的端部连接到第二缓冲溶液罐（104）的内部。通过这种布置，提供了能够有效地转移样品的样品分离/吸附装置。

6. 发明申请

US20080296158A1 DEVICE FOR ELECTROPHORESIS, DEVICE FOR TRANSFER, DEVICE FOR ELECTROPHORESIS AND TRANSFER, CHIP FOR ELECTROPHORESIS AND TRANSFER, AND METHOD FOR ELECTROPHORESIS, METHOD FOR TRANSFER, AND METHOD FOR ELECTROPHORESIS AND TRANSFER 审中-公开
标题翻译：用于电泳的装置，用于转印的装置，用于电泳和转印的装置，用于电泳和转印的芯片，以及用于电泳的方法，用于转移的方法，以及用于电泳和转移的方法
公开(公告)号：US20080296158A1
公开(公告)日：2008-12-04
申请号：US12130691
申请日：2008-05-30
申请人： Yuji Maruo , Yutaka Unuma , Atsunori Hiratsuka , Hideki Kinoshita , Kenji Yokoyama , Koji Sakairi , Satonari Akutsu
发明人： Yuji Maruo , Yutaka Unuma , Atsunori Hiratsuka , Hideki Kinoshita , Kenji Yokoyama , Koji Sakairi , Satonari Akutsu
IPC分类号： C25B7/00 , C25B9/00
CPC分类号： G01N27/44704 , B01L3/50273
摘要： A device for electrophoresis applies a voltage to a medium in contact with a plurality of electric conductors so that a potential of adjacent conductors is within a certain range. This allows preventing decline in electrophoresis speed. A device for electrophoresis and transfer includes an electrode having a plurality of electrode regions being insulated one another and arranged in a specific direction. This allows providing a practical and easy-to-use device for electrophoresis and transfer. A device for transfer alters an applied voltage or applied voltage duration to a certain position to another position. This allows improving transfer efficiency.
摘要翻译：用于电泳的装置将电压施加到与多个电导体接触的介质，使得相邻导体的电位在一定范围内。这样可以防止电泳速度下降。用于电泳和转印的装置包括具有彼此绝缘并沿特定方向布置的多个电极区域的电极。这允许提供用于电泳和转移的实用且易于使用的装置。用于传送的装置将施加的电压或施加的电压持续时间改变到某个位置到另一位置。这样可以提高传输效率。

7. 发明申请

US20050177071A1 Invasive appliance 审中-公开
标题翻译：有创器具
公开(公告)号：US20050177071A1
公开(公告)日：2005-08-11
申请号：US10516253
申请日：2003-08-29
申请人： Hiroshi Nakayama , Fumiaki Emoto , Atsunori Hiratsuka
发明人： Hiroshi Nakayama , Fumiaki Emoto , Atsunori Hiratsuka
IPC分类号： A61B5/15 , A61B5/00 , B65D81/00
CPC分类号： A61B5/15136 , A61B5/150022 , A61B5/150068 , A61B5/150076 , A61B5/150083 , A61B5/150091 , A61B5/150114 , A61B5/150122 , A61B5/150129 , A61B5/150137 , A61B5/150389 , A61B5/150412 , A61B5/150442 , A61B5/150503 , A61B5/150977 , A61B5/15107 , A61B5/15117 , A61M5/422
摘要： An invasive apparatus for obtaining an in vivo fluid is provided wherein the invasive apparatus includes a different stimulus applying portion for applying a stimulus different from a stimulus applied by an invasive portion to an organism in a leading end area other than a hole through which the invasive portion exits. The invasive portion is a hollow tube, knife, needle or laser beam, and the different stimulus is a mechanical stimulus. A recessed portion and/or raised portion is formed in the area other than the hole, and the different stimulus applying portion is the recessed portion and/or raised portion. The different stimulus is given by the recessed portion and/or raised portion.
摘要翻译：提供了一种用于获得体内流体的侵入性装置，其中所述侵入性装置包括不同的刺激施加部分，用于将不同于由侵入部分施加的刺激的刺激施加到除了侵入性的孔之外的前端区域中的生物体部分退出。侵入部分是中空管，刀，针或激光束，并且不同的刺激是机械刺激。在孔以外的区域形成有凹部和/或凸部，不同的刺激施加部是凹部和/或凸起部。不同的刺激由凹部和/或凸起部分给出。

8. 发明申请

US20110114485A1 ELECTROPHORESIS APPARATUS AND ELECTROPHORESIS METHOD 有权
标题翻译：电泳装置和电泳方法
公开(公告)号：US20110114485A1
公开(公告)日：2011-05-19
申请号：US13054271
申请日：2009-07-15
申请人： Koji Sakairi , Satonari Akutsu , Yuji Maruo , Takateru Matsunaga , Yutaka Unuma , Atsunori Hiratsuka , Hideki Kinoshita , Nao Sakaguchi , Kenji Yokoyama
发明人： Koji Sakairi , Satonari Akutsu , Yuji Maruo , Takateru Matsunaga , Yutaka Unuma , Atsunori Hiratsuka , Hideki Kinoshita , Nao Sakaguchi , Kenji Yokoyama
IPC分类号： G01N27/447 , G01N27/453
CPC分类号： G01N27/44773
摘要： An electrophoresis apparatus includes a sample separating section for containing a sample separating medium for separating a sample in a horizontal direction, the sample separating section containing the sample separating medium in such a manner that the sample separating medium has an exposed portion at least one end of a surface of the sample separating medium, the surface being in parallel with the horizontal direction; and medium connecting means for connecting a sample containing medium to the sample separating medium at a connecting region, the sample containing medium containing a sample, and the connecting region satisfying a particular equation. By this, an electrophoresis technique with better accuracy than conventional arts can be provided.
摘要翻译：电泳装置包括样品分离部分，用于容纳用于在水平方向上分离样品的样品分离介质，样品分离部分包含样品分离介质，使得样品分离介质具有暴露部分，至少一端所述样品分离介质的表面与所述水平方向平行; 以及介质连接装置，用于在连接区域连接包含样品的介质到样品分离介质，所述样品包含含有样品的介质和满足特定等式的连接区域。由此，可以提供比现有技术更好的精度的电泳技术。

9. 发明授权

US07087149B1 Biosensor 有权
标题翻译：生物传感器
公开(公告)号：US07087149B1
公开(公告)日：2006-08-08
申请号：US09958671
申请日：2000-04-13
申请人： Hitoshi Muguruma , Atsunori Hiratsuka , Isao Karube
发明人： Hitoshi Muguruma , Atsunori Hiratsuka , Isao Karube
IPC分类号： G01N27/327 , C08F2/46 , C12Q1/00
CPC分类号： C12Q1/002
摘要： A novel biosensor was accomplished using a plasma-polymerized membrane. The biosensor of the present invention is a high-performance biosensor produced by a simpler method and applicable to a wide range of fields.
摘要翻译：使用等离子体聚合膜完成了新颖的生物传感器。本发明的生物传感器是通过更简单的方法制造并适用于广泛领域的高性能生物传感器。

10. 发明申请

US20060137983A1 Method of controlling migration of substance 有权
标题翻译：控制物质迁移的方法
公开(公告)号：US20060137983A1
公开(公告)日：2006-06-29
申请号：US10533015
申请日：2003-10-28
申请人： Kazuyoshi Yano , Isao Karube , Atsunori Hiratsuka , Shuo-Wen Tsai
发明人： Kazuyoshi Yano , Isao Karube , Atsunori Hiratsuka , Shuo-Wen Tsai
IPC分类号： C07K1/26 , B01D57/02 , G01N27/447
CPC分类号： B01D57/02 , G01N27/44773 , G01N27/44791
摘要： Transfer of fluid substances, and/or substances comprised in fluid substances, is controlled by introducing a separation medium, which prevents transfer of the fluid substances, and/or the substances comprised in the fluid substances, to an intermediate cavity connecting a first cavity and a second cavity; and introducing a connection medium to replace the separation medium and thereby start substance transfer to the second cavity. Substance transfer may be readily controlled without relying on mechanical means. Based on the present invention, two-dimensional electrophoretic analysis can be readily implemented on a chip.
摘要翻译：通过引入分离介质来控制流体物质和/或包含在流体物质中的物质，该分离介质防止流体物质和/或包含在流体物质中的物质转移到连接第一空腔和第二腔; 并引入连接介质以更换分离介质，从而开始物质转移到第二腔。可以容易地控制物质转移，而不依赖于机械装置。基于本发明，可以容易地在芯片上实现二维电泳分析。

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