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    • 1. 发明授权
    • Microemulsion preconcentrate, microemulsion and use thereof
    • 微乳液预浓缩液,微乳液及其用途
    • US08158134B1
    • 2012-04-17
    • US10110212
    • 2000-10-20
    • Andreas SupersaxoMarc Antoine WederHans Georg Weder
    • Andreas SupersaxoMarc Antoine WederHans Georg Weder
    • A61K9/00A61K9/46C11D17/00
    • A61K9/1075A61K9/4858A61K38/13
    • The invention relates to compositions in the form of microemulsion preconcentrates that contain (a) a mixture that consists of a medium-chain triglyceride and an omega-9 fatty acid and/or an omega-6 fatty acid; and (b) a surface-active component that contains a polyoxethylene tenside. When contacted with water or with an aqueous medium these microemulsion preconcentrates form microemulsions. The microemulsions of the O/W type have an average particle size below 150 nm, preferably below 100 nm. The inventive microemulsion preconcentrates and microemulsions are suitable for use as vehicles for substances, namely active agents, that are hardly soluble in water, but soluble in components (a) and/or (b). In the aqueous phase, said microemulsions may contain water-soluble substances.
    • 本发明涉及微乳液预浓缩物形式的组合物,其含有(a)由中链甘油三酯和ω-9脂肪酸和/或ω-6脂肪酸组成的混合物; 和(b)含有聚氧乙烯表面活性剂的表面活性成分。 当与水或水介质接触时,这些微乳液预浓缩物形成微乳液。 O / W型的微乳液的平均粒度小于150nm,优选低于100nm。 本发明的微乳液预浓缩物和微乳液适用于难溶于水但可溶于组分(a)和/或(b)的物质即活性剂的载体。 在水相中,所述微乳液可含有水溶性物质。