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    • 1. 发明申请
    • Method and apparatus of sterilization using monochromatic UV radiation source
    • 使用单色紫外线辐射源灭菌的方法和设备
    • US20050079096A1
    • 2005-04-14
    • US10939818
    • 2004-09-13
    • Susan Brown-SkrobotJames EbelJohn EnnsGregory HillAllan Kimble
    • Susan Brown-SkrobotJames EbelJohn EnnsGregory HillAllan Kimble
    • A61L2/10A61L12/06B65B25/00
    • A61L12/063A61L2/10B65B25/008
    • This invention provides a process of sterilizing a medical device, and preferably the contents of a sealed container which comprises said medical device, comprising the step of exposing said medical device to monochromatic ultraviolet radiation whereby the Dvalue of Bacillus stearothermophilus (ATCC 7953) is at least 23.7 mJ/cm2 monochromatic ultraviolet radiation at 257 nm to the spore. Further, this invention provides a process of sterilizing a medical device comprising the step of subjecting said medical device to monochromatic ultraviolet radiation wherein the minimum total energy density of said monochromatic ultraviolet radiation at 257 nm which reaches the microorganisms present on said medical device is at least 284 mJ/cm2. This invention further provides an apparatus for delivering UV radiation to a medical device for sterilization comprising a laser and a scanner for the laser such that at least 284 mJ/cm2 at 257 nm is applied to a treatment area for said medical device. This invention provides a process and apparatus in which sterilization can be achieved in less than 20 seconds, preferably less than 15 seconds, more preferably in less than 5 seconds. The process and apparatus are efficient and continuous.
    • 本发明提供了一种对医疗装置进行灭菌的方法,优选包括所述医疗装置的密封容器的内容物,其包括将所述医疗装置暴露于单色紫外线辐射的步骤,由此使嗜热脂肪芽孢杆菌(ATCC 7953)的D值至少为 对于孢子,在257nm处具有23.7mJ / cm 2的单色紫外线辐射。 此外,本发明提供一种消毒医疗装置的方法,包括以下步骤:对所述医疗装置进行单色紫外线辐射,其中到达所述医疗装置上存在的微生物的257nm处的所述单色紫外线辐射的最小总能量密度至少为 284mJ / cm 2。 本发明还提供了一种用于将UV辐射递送到用于灭菌的医疗装置的装置,包括用于激光的激光器和扫描器,使得在257nm处的至少284mJ / cm 2被施加到所述医疗装置的治疗区域。 本发明提供一种方法和装置,其中可以在少于20秒,优选小于15秒,更优选在少于5秒内实现灭菌。 该方法和设备是有效和连续的。