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1. 发明申请

US20050183055A1 Method and apparatus for automating the design of programmable logic devices 审中-公开
标题翻译：用于自动化可编程逻辑器件设计的方法和装置
公开(公告)号：US20050183055A1
公开(公告)日：2005-08-18
申请号：US10771596
申请日：2004-02-04
申请人： Alfredo Herrera
发明人： Alfredo Herrera
IPC分类号： G06F17/50
CPC分类号： G06F17/5054 , G06F17/5072
摘要： The design of programmable logic devices, such as FPGAs, may be automated to allow scripts, setup files, and other tool files to be created directly from hollowed and filled netlist, and data-path and design constraint files without extensive human intervention. This allows an FPGA design to be created directly from a logic file to accelerate the FPGA design process. Once hollowed and filled netlists, and data-path and design constraint files have been generated from a design in a standard fashion, the implementation of that design onto an FPGA in an optimized fashion is automated by providing a computer program that is capable of implementing the design, testing the design, evaluating the test results, and altering the design to arrive at a more optimal design. The process may include several steps, such as initial placement of logic groups, sizing of logic groups and FPGA selection, timing analysis, and filled netlist complete design review. The steps may be iterative.
摘要翻译：可编程逻辑器件（例如FPGA）的设计可以自动化，以便直接从中空填充的网表，数据路径和设计约束文件直接创建脚本，设置文件和其他工具文件，而无需广泛的人为干预。这允许直接从逻辑文件创建FPGA设计，以加速FPGA设计过程。一旦中空和填充的网表，并且已经以标准方式从设计生成了数据路径和设计约束文件，则以优化的方式将该设计实现到FPGA上，通过提供能够实现设计，测试设计，评估测试结果，改变设计以获得更优化的设计。该过程可以包括几个步骤，例如逻辑组的初始放置，逻辑组的大小和FPGA选择，时序分析和填充的网表完整设计审查。这些步骤可能是迭代的。

2. 发明授权

US07189316B2 Pulsed field electrophoresis chambers, accessories and method of utilization for separation of DNA molecules 失效
标题翻译：脉冲场电泳室，附件和分离DNA分子的利用方法
公开(公告)号：US07189316B2
公开(公告)日：2007-03-13
申请号：US10070878
申请日：2001-06-07
申请人： Ana Maria Riverón Rojas , Lilia López Cánova , Oscar Arencibia Díaz , Jose Alfredo Herrera Isidrón , Gabriel Pérez Pérez , Esther Orozco Orozco , Carlos Alberto Cánino Ramos , Luis Mariano Batista Santiler , Regnar Gigato Pérez , Leonardo Ruíz Esquivel , Maria Dolores Noa Blanco , Elisa Javert Higginson
发明人： Ana Maria Riverón Rojas , Lilia López Cánova , Oscar Arencibia Díaz , Jose Alfredo Herrera Isidrón , Gabriel Pérez Pérez , Esther Orozco Orozco , Carlos Alberto Cánino Ramos , Luis Mariano Batista Santiler , Regnar Gigato Pérez , Leonardo Ruíz Esquivel , Maria Dolores Noa Blanco , Elisa Javert Higginson
IPC分类号： G01N27/447
CPC分类号： G01N27/44773 , G01N27/44704
摘要： Methods of use, accessories and chambers, optimal for performing Pulsed Field Gel Electrophoresis (PFGE) of DNA molecules in ‘Contour Clamped Homogeneous Electric Field’ (CHEF) and ‘Transversal Alternating Field Electrophoresis’ (TAFE) systems, are provided herein. DNA molecules are rapidly separated in the minigels of these chambers. The sizes of chambers and accessories are determined by the separation between the opposite polarity electrodes; which is comprised between 6.2 and 15 cm. Reproducibility of molecule separation is achieved because the accessories warrant homogeneous electric resistance in the buffer and minigels. Chambers allow a high-throughput sample format using the reagents efficiently. It is attained excluding the non-useful electrophoresis zones For a better optimization, TAFE chambers have several useful electrophoresis zones (UEZ), each carrying a minigel. One or more UEZ can be activated at will in the electrophoresis, to vary the number of minigels, the number of samples and the amount of buffer among the experiments. TAFE chambers having ‘inverted electrode configuration’ with the cathodes at their bottom are presented.
摘要翻译：本文提供了使用“轮廓夹紧均匀电场”（CHEF）和“横向交替场电泳”（TAFE）系统进行DNA分子的脉冲场凝胶电泳（PFGE）的最佳使用方法，附件和室。 DNA分子在这些室的微型凝胶中快速分离。室和附件的尺寸由相反极性电极之间的间隔决定; 它在6.2和15厘米之间。实现了分子分离的重现性，因为这些附件保证了缓冲液和小型凝胶中的均匀的电阻。室可以高效地使用试剂进行高通量样品。实现排除非有用的电泳区域为了更好地优化，TAFE室具有几个有用的电泳区（UEZ），每个携带微型玻璃。可以在电泳中随意激活一个或多个UEZ，以便在实验中改变微胶囊数量，样品数量和缓冲液量。提出了具有“倒置电极配置”的底部具有阴极的TAFE室。

3. 发明授权

US06800933B1 Integrated circuit cooling device 有权
标题翻译：集成电路冷却装置
公开(公告)号：US06800933B1
公开(公告)日：2004-10-05
申请号：US09840019
申请日：2001-04-23
申请人： Charles R. Mathews , Miguel Santana, Jr. , Alfredo Herrera
发明人： Charles R. Mathews , Miguel Santana, Jr. , Alfredo Herrera
IPC分类号： H01L2334
CPC分类号： H01L35/34 , H01L23/38 , H01L2924/0002 , Y10S257/93 , H01L2924/00
摘要： Various embodiments of a semiconductor-on-insulator substrate incorporating a Peltier effect heat transfer device and methods of fabricating the same are provided. In one aspect, a circuit device is provided that includes an insulating substrate, a semiconductor structure positioned on the insulating substrate and a Peltier effect heat transfer device coupled to the insulating substrate to transfer heat between the semiconductor structure and the insulating substrate.
摘要翻译：提供了包含珀尔帖效应传热装置的绝缘体上半导体衬底的各种实施例及其制造方法。一方面，提供了一种电路装置，其包括绝缘基板，位于绝缘基板上的半导体结构和耦合到该绝缘基板的珀尔帖效应传热装置，以在半导体结构和绝缘基板之间传递热量。

4. 发明申请

US20070179663A1 Method and apparatus for manufacturing data indexing 有权
标题翻译：用于制造数据索引的方法和装置
公开(公告)号：US20070179663A1
公开(公告)日：2007-08-02
申请号：US11341701
申请日：2006-01-27
申请人： Michael McIntyre , Alex Bierwag , Charlie Reading , Alfredo Herrera
发明人： Michael McIntyre , Alex Bierwag , Charlie Reading , Alfredo Herrera
IPC分类号： G06F19/00
CPC分类号： G05B23/0229 , G05B23/0264 , Y10S707/99936 , Y10S707/99937 , Y10S707/99942
摘要： A method, apparatus, and a system for generating an index for storing data. A pattern associated with a first set of data is determined. The first set of data is stored. A determination is made as to whether the pattern associated with a second set of data corresponds to the pattern associated with the first set of data. An index associated with the first set of data is correlated to the second set of data in response to determining that the pattern associated with the second set of data corresponds to the pattern associated with the first set of data.
摘要翻译：一种用于生成用于存储数据的索引的方法，装置和系统。确定与第一组数据相关联的模式。第一组数据被存储。确定与第二组数据相关联的模式是否对应于与第一组数据相关联的模式。响应于确定与第二组数据相关联的模式对应于与第一组数据相关联的模式，与第一组数据相关联的索引与第二组数据相关。

5. 发明授权

US08034225B2 Pulsed field gel electrophoresis chambers, accessories and methods of use for the separation of DNA molecules 失效
标题翻译：脉冲场凝胶电泳室，附件和分离DNA分子的方法
公开(公告)号：US08034225B2
公开(公告)日：2011-10-11
申请号：US11643454
申请日：2006-12-21
申请人： Ana Maria Riveron Rojas , Lilia Lopez Canovas , Oscar Arencibia Diaz , Jose Alfredo Herrera Isidron , Gabriel Perez Perez , Esther Orozco Orozco , Carlos Alberto Canino Ramos , Luis Mariano Batista Santiler , Regnar Gigato Perez , Leonardos Ruiz Esquvel , Maria Dolores Noa Blanco , Elisa Javert Higginson
发明人： Ana Maria Riveron Rojas , Lilia Lopez Canovas , Oscar Arencibia Diaz , Jose Alfredo Herrera Isidron , Gabriel Perez Perez , Esther Orozco Orozco , Carlos Alberto Canino Ramos , Luis Mariano Batista Santiler , Regnar Gigato Perez , Leonardos Ruiz Esquvel , Maria Dolores Noa Blanco , Elisa Javert Higginson
IPC分类号： G01N27/453
CPC分类号： G01N27/44773 , G01N27/44704
摘要： Methods of use, accessories and chambers, optimal for performing Pulsed Field Gel Electrophoresis (PFGE) of DNA molecules in ‘Contour Clamped Homogeneous Electric Field’ (CHEF) and ‘Transversal Alternating Field Electrophoresis’ (TAFE) systems, are provided herein. DNA molecules are rapidly separated in the minigels of these chambers. The sizes of chambers and accessories are determined by the separation between the opposite polarity electrodes; which is comprised between 6.2 and 15 cm. Reproducibility of molecule separation is achieved because the accessories warrant homogeneous electric resistance in the buffer and minigels. Chambers allow a high-throughput sample format using the reagents efficiently. It is attained excluding the non-useful electrophoresis zones. For a better optimization, TAFE chambers have several useful electrophoresis zones (UEZ), each carrying a minigel. One or more UEZ can be activated at will in the electrophoresis, to vary the number of minigels, the number of samples and the amount of buffer among the experiments. TAFE chambers having ‘inverted electrode configuration’ with the cathodes at their bottom are presented.
摘要翻译：本文提供了使用“轮廓夹紧均匀电场”（CHEF）和“横向交替场电泳”（TAFE）系统进行DNA分子的脉冲场凝胶电泳（PFGE）的最佳使用方法，附件和室。 DNA分子在这些室的微型凝胶中快速分离。室和附件的尺寸由相反极性电极之间的间隔决定; 它在6.2和15厘米之间。实现了分子分离的重现性，因为这些附件保证了缓冲液和小型凝胶中的均匀的电阻。室可以高效地使用试剂进行高通量样品。实现排除非有用的电泳区域。为了更好的优化，TAFE室具有几个有用的电泳区（UEZ），每个携带一个微型玻璃。可以在电泳中随意激活一个或多个UEZ，以便在实验中改变微胶囊数量，样品数量和缓冲液量。提出了具有“倒置电极配置”的底部具有阴极的TAFE室。

6. 发明授权

US07556726B2 Circuit for imposing voltages on the electrodes of trays used in the CHEF pulsed field electrophoresis system 有权
标题翻译：用于在CHEF脉冲场电泳系统中使用的托盘电极施加电压的电路
公开(公告)号：US07556726B2
公开(公告)日：2009-07-07
申请号：US10479828
申请日：2002-06-07
申请人： José Alfredo Herrera Isidron , Ana Maria Riveron Rojas , Carlos Alberto Cánino Ramos , Lilia Lopez Canovas , Maria Dolores Noa Blanco
发明人： José Alfredo Herrera Isidron , Ana Maria Riveron Rojas , Carlos Alberto Cánino Ramos , Lilia Lopez Canovas , Maria Dolores Noa Blanco
IPC分类号： G01N27/453
CPC分类号： G01N27/44713 , G01N27/44773
摘要： Circuit to clamp the voltages in the electrodes of the CHEF system chambers of Pulsed Field Gel Electrophoresis (PFGE) which is formed by two identical clamping circuits that are connected to a power supply through an alternator and only one of the two circuits receives electric power at the same time. Each clamping circuit is formed by several resistors and diodes connected in series to form a voltage divider. Voltage repeaters are connected to the nodes formed in the union of two resistors. Each repeater is connected to a pair of electrodes that should be polarized at the same potential. Diodes are introduced to correct small errors in the voltage pattern applied to the electrodes. The circuit is able to maintain the potential of each electrode in front of the variations of conductivity that occur inside the chamber during the electrophoresis. This way each imposition circuit generates a homogeneous electric field of same value and different direction in a PFGE chamber of the CHEF system. Chambers with different number, disposition and separation among the electrodes can be polarized with this circuit.
摘要翻译：用于钳位由脉冲场凝胶电泳（PFGE）的CHEF系统室的电极中的电压的电路，其由两个相同的钳位电路形成，钳位电路通过交流发电机连接到电源，并且仅两个电路中的一个接收电力同一时间。每个钳位电路由串联连接的几个电阻和二极管形成一个分压器。电压中继器连接到形成在两个电阻的并联中的节点。每个中继器连接到应该在相同电位极化的一对电极。引入二极管以校正施加到电极的电压图案中的小误差。该电路能够在电泳期间在室内发生的电导率变化之前保持每个电极的电位。这样，每个拼版电路在CHEF系统的PFGE室中产生相同值和不同方向的均匀电场。电极之间具有不同数量，配置和分离的室可以用该电路进行极化。

7. 发明申请

US20060034806A1 Trichoderma SPP strains with high capactiy of fungus biological control and selection process thereof by molecular markers 有权
标题翻译：木霉菌SPP菌株具有较高的真菌生物控制能力，并通过分子标记筛选其过程
公开(公告)号：US20060034806A1
公开(公告)日：2006-02-16
申请号：US11244089
申请日：2005-10-06
申请人： Alfredo Herrera-Estrella , Rafael Galdames-Gutierrez , Jose Martinez-Hernandez
发明人： Alfredo Herrera-Estrella , Rafael Galdames-Gutierrez , Jose Martinez-Hernandez
IPC分类号： C12N1/16 , A01N63/04
CPC分类号： C12R1/885 , A01N63/04 , C12Q1/18 , G01N2333/37
摘要： Trichoderma spp. strains with high capacity for fungus biological control in wide ranges of temperature and pH are described, such strains being compatible with each other. Likewise, a process of selection of such strains through molecular markers is described. The described process reduce the number of necessary experiments to determine if a Trichoderma strain, not previously described, can display a biological activity more acceptable than those well known.
摘要翻译：木霉属描述了在宽温度和pH范围内具有高真菌生物控制能力的菌株，这些菌株彼此相容。同样，描述了通过分子标记物选择这些菌株的方法。所描述的方法减少了必要的实验的数量，以确定以前未描述的木霉菌株是否可以显示出比所熟知的更可接受的生物活性。

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