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1. 发明申请

US20050182453A1 Treatment of epilepsy by high frequency electrical stimulation and/or drug stimulation 审中-公开
标题翻译：通过高频电刺激和/或药物刺激治疗癫痫
公开(公告)号：US20050182453A1
公开(公告)日：2005-08-18
申请号：US11103945
申请日：2005-04-12
申请人： Todd Whitehurst , Edward Overstreet , Albert Maltan
发明人： Todd Whitehurst , Edward Overstreet , Albert Maltan
IPC分类号： A61M5/142 , A61N1/18 , A61N1/36
CPC分类号： A61N1/37205 , A61M5/14276 , A61N1/06 , A61N1/36064 , A61N1/36082 , A61N1/36135 , A61N1/36157 , A61N1/36171
摘要： Exemplary methods of treating a patient with epilepsy include applying a stimulus to a stimulation site within the patient with an implanted system control unit in accordance with one or more stimulation parameters. The stimulus includes a stimulation current having a frequency substantially equal to or greater than 400 Hz. Exemplary systems for treating a patient with epilepsy include a system control unit configured to apply a stimulus to a stimulation site within the patient in accordance with one or more stimulation parameters. The stimulus includes a stimulation current having a frequency substantially equal to or greater than 400 Hz.
摘要翻译：治疗患有癫痫患者的示例性方法包括根据一个或多个刺激参数用植入的系统控制单元向患者内的刺激部位施加刺激。刺激包括具有基本上等于或大于400Hz的频率的刺激电流。用于治疗患有癫痫患者的示例性系统包括系统控制单元，其被配置为根据一个或多个刺激参数将刺激应用于患者内的刺激部位。刺激包括具有基本上等于或大于400Hz的频率的刺激电流。

2. 发明申请

US20070021804A1 Stimulation using a microstimulator to treat tinnitus 审中-公开
标题翻译：刺激使用微刺激器治疗耳鸣
公开(公告)号：US20070021804A1
公开(公告)日：2007-01-25
申请号：US10854108
申请日：2004-05-26
申请人： Albert Maltan , Todd Whitehurst
发明人： Albert Maltan , Todd Whitehurst
IPC分类号： A61N1/00
CPC分类号： A61N1/361 , A61N1/0526 , A61N1/36036 , A61N1/37205
摘要： An implantable microstimulator and a stimulating electrode are implanted to treat tinnitus. The microstimulator is connected to the stimulating electrode via a short, flexible lead. The electrode is implanted in the promontory of the cochlea or in the cochlear round window niche to deliver electrical stimulation to the auditory nervous system and thereby suppress or mask the tinnitus. The microstimulator may be surgically implanted through the ear canal, via a mastoidectomy or through the middle fossa, i.e., a supra-meatal approach. The microstimulator may be placed in middle ear cavity, a bony recess created in the bone surrounding the middle ear, the mastoid, the cochlea or a part of the temporal bone. In addition, the system may further include a test electrode, a test stimulator and a remote programming device that employs a bi-directional radio-frequency communication link to control and program the microstimulator and the test stimulator.
摘要翻译：植入微型刺激器和刺激电极植入治疗耳鸣。微型激励器通过短而柔性的引线连接到刺激电极。将电极植入耳蜗的耳朵或耳蜗圆窗口，以将电刺激输送到听觉神经系统，从而抑制或掩蔽耳鸣。微型刺激器可以通过耳道，通过乳突切除术或通过中窝进行外科手术植入，即超级肉眼方法。微型刺激器可以放置在中耳腔中，在围绕中耳的骨骼中产生的骨凹部，乳突，耳蜗或颞骨的一部分。此外，该系统还可以包括测试电极，测试激励器和远程编程设备，其采用双向射频通信链路来控制和编程微型激励器和测试激励器。

3. 发明申请

US20050157896A1 Hollow tube enclosing an implantable personal sound link module 审中-公开
标题翻译：封闭一个可植入式个人声音连接模块的空心管
公开(公告)号：US20050157896A1
公开(公告)日：2005-07-21
申请号：US11079641
申请日：2005-03-14
申请人： Albert Maltan , Janusz Kuzma
发明人： Albert Maltan , Janusz Kuzma
IPC分类号： H04R25/00
CPC分类号： H04R25/606
摘要： A hollow tube device enclosing a personal sound link module is inserted into a tunnel (40) made through the soft tissue connecting the retro-auricular space (50) with the ear canal (30). The hollow tube device contains an acoustic transducer (65), located at the distal part (68) of an enclosed case, close to or inside the ear canal, an antenna (64) that receives and also potentially sends signals to a remote source, signal processing circuitry (67), telemetry circuitry (69), a power source (66) that powers the device, and possibly a microphone (63). Signals transmitted from a remote source are received through the antenna and telemetry circuitry, processed, and presented to the acoustic transducer, where they are converted to sound waves broadcast into the user's ear canal. The remote source may be a radio station, radio receiver, CD player, DVD player, tape player, audio system, telephone, TV receiver or station, or other source of audio signals intended to be heard privately by the user.
摘要翻译：封闭个人声音连接模块的中空管装置被插入穿过将耳环空间（50）与耳道（30）连接的软组织制成的隧道（40）中。中空管装置包含位于封闭壳体的远端部分（68）附近或耳道内的声学换能器（65），接收并且还可能向远程源发送信号的天线（64）信号处理电路（67），遥测电路（69），为设备供电的电源（66）以及可能的麦克风（63）。从远程源发送的信号通过天线和遥测电路被接收，被处理并呈现给声换能器，在那里它们被转换成广播到用户耳道的声波。远程源可以是用户私下听到的无线电台，无线电接收机，CD播放器，DVD播放器，磁带机，音频系统，电话机，电视接收机或电台，或者其它的音频信号源。

4. 发明申请

US20050031145A1 Novel hearing aid design 失效
标题翻译：新型助听器设计
公开(公告)号：US20050031145A1
公开(公告)日：2005-02-10
申请号：US10932813
申请日：2004-09-01
申请人： Albert Maltan , Alfred Mann , James McGivern , Philip Lee
发明人： Albert Maltan , Alfred Mann , James McGivern , Philip Lee
IPC分类号： H04R25/00 , H04R25/02
CPC分类号： H04R25/505 , H04R25/554 , H04R25/558 , H04R25/60 , H04R25/65 , H04R25/658 , H04R2225/51 , H04R2225/67 , H04R2420/07
摘要： A hearing aid module is shaped for insertion into a tunnel made through the soft tissue that connects the retro-auricular space with the ear canal. The hearing aid module contains a speaker or auditory transducer, a battery or other power source powering the module, signal processing circuitry, and a microphone. Telemetry circuitry within the module allows the signal processing circuitry to be programmed with a desired frequency response or signal processing strategy using an external programming unit. A remote control unit permits the user to make simple adjustments, such as volume and/or tone (frequency) control.
摘要翻译：助听器模块被成形为插入到通过将耳环空间与耳道连接的软组织制成的隧道中。助听器模块包括扬声器或听觉换能器，为模块供电的电池或其他电源，信号处理电路和麦克风。模块内的遥测电路允许使用外部编程单元对信号处理电路进行所需的频率响应或信号处理策略的编程。遥控单元允许用户进行简单的调节，例如音量和/或音调（频率）控制。

5. 发明申请

US20070282396A1 System and method of contra-lateral ear stimulation for preserving neuronal survival and plasticity of the auditory system prior to permanent intra-cochlear implantation 审中-公开
标题翻译：用于在永久性耳蜗植入之前保持听觉系统的神经元存活和可塑性的对侧耳刺激的系统和方法
公开(公告)号：US20070282396A1
公开(公告)日：2007-12-06
申请号：US10954321
申请日：2004-09-30
申请人： Edward Overstreet , Albert Maltan , Janusz Kuzma
发明人： Edward Overstreet , Albert Maltan , Janusz Kuzma
IPC分类号： A61N1/36
CPC分类号： A61N1/36036 , A61N1/37205
摘要： An implantable microstimulator, or equivalent neural stimulator, generates a relatively simple signal containing temporally challenging information and delivers such signal to the middle or outer portion of the ear contra-lateral to an ear having a cochlear implant of a bilaterally deafened patient. Such stimulation delivered to the contra lateral ear advantageously increases the survival rate of neurons therein, and further helps maintain or extend the plasticity of the higher auditory pathways of the contra-lateral ear, thereby allowing a cochlear implant to be more effectively used in such ear at a later date. The stimulation provided by the microstimulator, or equivalent simple neural stimulator, need not be continuous, but may be provided only during limited periods of time each day, or only on selected days. Further, such stimulation preserves whatever residual hearing may be left in the contra lateral ear.
摘要翻译：植入式微刺激器或等效神经刺激器产生包含时间上具有挑战性的信息的相对简单的信号，并且将这种信号传递到具有双侧耳聋患者的耳蜗植入物的耳朵的中部或外部部分。传递到对侧耳的这种刺激有利地增加其中神经元的存活率，并且进一步有助于维持或延长对侧耳的较高听觉通路的可塑性，从而允许在这种耳朵中更有效地使用人工耳蜗晚一些。由微刺激器提供的刺激或相当的简单神经刺激器不必是连续的，而是可以仅在每天的有限时间段期间提供，或者仅在选定的日子提供。此外，这种刺激保留在对侧耳中留下的残留听力。

6. 发明申请

US20070282395A1 System and method for preserving neuronal survival and plasticity of the auditory system prior to permanent intra-cochlear implantation 审中-公开
标题翻译：在永久性耳蜗植入之前保持听觉系统的神经元存活和可塑性的系统和方法
公开(公告)号：US20070282395A1
公开(公告)日：2007-12-06
申请号：US10954320
申请日：2004-09-30
申请人： Albert Maltan , Edward Overstreet , Janusz Kuzma
发明人： Albert Maltan , Edward Overstreet , Janusz Kuzma
IPC分类号： A61N1/36
CPC分类号： A61N1/36036 , A61N1/37205
摘要： A system and method uses an electrical stimulator to stimulate the auditory system with a relatively simple signal that contains temporally challenging information in order to preserve neuronal survival and plasticity of the auditory system, and also to preserve residual hearing. The stimulation provided need not be continuous, but may be provided only during limited periods of time each day, or only on selected days. The system or method is particularly suited for very young children who acquire hearing impairment or deafness early in life and who may not yet be ready for a cochlear implant. The invention requires only minimal surgical intervention, if any, and may be carried out without the need for intra-cochlear electrodes. Under special circumstances, the invention may also be used with older children or adults with a hearing impairment or deafness.
摘要翻译：系统和方法使用电刺激器以相对简单的信号刺激听觉系统，该信号包含时间上具有挑战性的信息，以便保持听觉系统的神经元存活和可塑性，并且还保留残留听力。提供的刺激不需要是连续的，而是可以仅在每天有限的时间段内提供，或仅在选定的日子提供。该系统或方法特别适用于在生命早期获得听力障碍或耳聋的可能尚未准备好进行人工耳蜗的年幼儿童。本发明仅需要最小的手术干预（如果有的话），并且可以在不需要耳蜗电极的情况下进行。在特殊情况下，本发明也可与具有听力障碍或耳聋的年龄较大的儿童或成年人一起使用。

7. 发明申请

US20050102006A1 Skull-mounted electrical stimulation system 审中-公开
标题翻译：头盔电刺激系统
公开(公告)号：US20050102006A1
公开(公告)日：2005-05-12
申请号：US10949067
申请日：2004-09-24
申请人： Todd Whitehurst , Rafael Carbunaru , Albert Maltan , Michael Faltys
发明人： Todd Whitehurst , Rafael Carbunaru , Albert Maltan , Michael Faltys
IPC分类号： A61M5/142 , A61M5/172 , A61N1/34 , A61N1/18
CPC分类号： A61M5/14276 , A61M5/1723 , A61M2205/3523 , A61M2205/52 , A61M2205/8243 , A61N1/36071
摘要： Systems and methods for applying electrical stimulation to the brain to treat headaches and neuralgia use at least one implantable system control unit (SCU), specifically an implantable signal/pulse generator (IPG) with one or more electrodes. The IPG is implanted in the skull and communicates with at least one external appliance, such as a Behind-the-Ear (BTE) unit. In a preferred embodiment, the system is capable of open- and closed-loop operation. In closed-loop operation, at least one SCU includes a sensor, and the sensed condition is used to adjust stimulation parameters.
摘要翻译：用于向大脑施加电刺激以治疗头痛和神经痛的系统和方法使用至少一个可植入系统控制单元（SCU），特别是具有一个或多个电极的可植入信号/脉冲发生器（IPG）。将IPG植入颅骨中并与至少一个外部设备（例如耳后（BTE））单元进行通信。在优选实施例中，系统能够进行开环和闭环操作。在闭环操作中，至少一个SCU包括传感器，并且使用感测到的条件来调整刺激参数。

8. 发明申请

US20070217640A1 Hearing Aid Design 失效
标题翻译：助听器设计
公开(公告)号：US20070217640A1
公开(公告)日：2007-09-20
申请号：US11752196
申请日：2007-05-22
申请人： Albert Maltan , Alfred Mann , James McGivern , Philip Lee
发明人： Albert Maltan , Alfred Mann , James McGivern , Philip Lee
IPC分类号： H04R25/00
CPC分类号： H04R25/505 , H04R25/554 , H04R25/558 , H04R25/60 , H04R25/65 , H04R25/658 , H04R2225/51 , H04R2225/67 , H04R2420/07
摘要： A hearing aid module is shaped for insertion into a tunnel made through the soft tissue that connects the retro-auricular space with the ear canal. The hearing aid module contains a speaker or auditory transducer, a battery or other power source powering the module, signal processing circuitry, a microphone, and a hollow tube which contains a steroid or drug. Telemetry circuitry within the module allows the signal processing circuitry to be programmed with a desired frequency response or signal processing strategy using an external programming unit. A remote control unit permits the user to make simple adjustments, such as volume and/or tone (frequency) control.
摘要翻译：助听器模块被成形为插入到通过将耳环空间与耳道连接的软组织制成的隧道中。助听器模块包含扬声器或听觉换能器，为模块供电的电池或其它电源，信号处理电路，麦克风和含有类固醇或药物的中空管。模块内的遥测电路允许使用外部编程单元对信号处理电路进行所需的频率响应或信号处理策略的编程。遥控单元允许用户进行简单的调节，例如音量和/或音调（频率）控制。

9. 发明申请

US20070213788A1 Electrical stimulation of the inner ear in patients with unilateral hearing loss 审中-公开
标题翻译：单侧听力损伤患者内耳电刺激
公开(公告)号：US20070213788A1
公开(公告)日：2007-09-13
申请号：US10941207
申请日：2004-09-15
申请人： Mary Osberger , Albert Maltan
发明人： Mary Osberger , Albert Maltan
IPC分类号： A61N1/00
CPC分类号： A61N1/0541 , A61N1/36036
摘要： For a patient having unilateral hearing loss, an extra-cochlear electrode is placed within the middle ear of the deaf ear, and is connected to a microstimulator that is implanted under the skin or recessed in the temporal bone or some other location in the skull near the deaf ear. In one preferred embodiment, the extra-cochlear electrode is a mesh ball electrode that is placed in the round window niche, on the promontory, or in some other extra-cochlear location, of the deaf ear. Whenever a trigger signal generated by a microphone is received by the microstimulator, the microstimulator generates a stimulus pulse that is applied to the mesh ball electrode. The electrical signal applied through the mesh ball electrode provides temporal information to supplement the sound signal that is received by the other, normally-functioning ear of the patient.
摘要翻译：对于具有单侧听力损失的患者，将耳蜗外的电极放置在聋耳的中耳内，并连接到微型刺激器，其被植入在皮肤下或凹陷在颞骨中或颅骨中的其他位置附近耳聋。在一个优选实施例中，耳蜗外电极是放置在聋耳的圆形窗口小龛，岬角或其他耳蜗外的位置。每当由微型激励器接收由麦克风产生的触发信号时，微型激励器产生施加到网状球电极的刺激脉冲。通过网球电极施加的电信号提供时间信息以补充由患者的另一个正常功能的耳朵接收的声音信号。

10. 发明申请

US20070213787A1 Soft, middle-ear electrode for suppressing tinnitis 审中-公开
标题翻译：软，中耳电极用于抑制炎症
公开(公告)号：US20070213787A1
公开(公告)日：2007-09-13
申请号：US10932812
申请日：2004-09-01
申请人： Janusz Kuzma , Albert Maltan
发明人： Janusz Kuzma , Albert Maltan
IPC分类号： A61N1/36
CPC分类号： H04R25/75 , A61N1/36036 , A61N1/361
摘要： A soft, ball-shaped middle-ear electrode is inserted and wedged into the natural cavity that exists in front of the round window. An electrical pulse generator connected to the soft, ball-shaped electrode provides electrical stimulation to the region surrounding the round window for the purpose of suppressing tinnitus or to improve hearing.
摘要翻译：柔软的球形中耳电极被插入并楔入存在于圆窗前面的自然腔中。连接到软的球形电极的电脉冲发生器为了抑制耳鸣或改善听力而向围绕圆窗的区域提供电刺激。

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