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    • 1. 发明申请
    • Optical Fiber
    • 光纤
    • US20070089462A1
    • 2007-04-26
    • US11538334
    • 2006-10-03
    • Julia FarroniAdrian CarterKanishka Tankala
    • Julia FarroniAdrian CarterKanishka Tankala
    • C03B37/023
    • G02B6/02114C03B37/01217C03B37/01231C03B2201/10C03B2201/12C03B2201/28C03B2201/31C03B2201/34C03B2201/42C03B2203/23C03B2203/31G02B6/024
    • An optical fiber comprises a photosensitive core that includes a concentration of a first material that increases the refractive index of the core and a concentration of a second material that is other than boron and that reduces the refractive index of the core. A cladding is disposed about the core for tending to confine light to the core. The fiber also includes at least one longitudinally extending region having a thermal coefficient of expansion that is different from the thermal coefficient of expansion of the cladding. In another embodiment, the core includes a concentration of germanium and a concentration of boron. Also disclosed is a polarization-maintaining double-clad (PM DC) fiber comprising one or both of at least one circular axially extending stress inducing region(s) and an inner cladding comprising a circular outer perimeter. Fibers according to the invention can include a rare earth dopant for emitting light of a selected wavelength responsive to being pumped by pump light of a pump wavelength that is different than the selected wavelength.
    • 光纤包括感光芯,其包括提高芯的折射率的第一材料的浓度和不同于硼的第二材料的浓度,并降低芯的折射率。 围绕芯部布置包层以倾向于将光限制在芯部上。 纤维还包括具有不同于包层的热膨胀系数的热膨胀系数的至少一个纵向延伸区域。 在另一个实施方案中,芯包括锗的浓度和硼的浓度。 还公开了一种包括至少一个圆形轴向延伸的应力诱导区域和包含圆形外周边的内包层中的一个或两个的偏振保持双包层(PMDC)光纤。 根据本发明的纤维可以包括用于发射选定波长的光的稀土掺杂剂,其响应于通过不同于所选波长的泵浦波长的泵浦光泵浦。
    • 4. 发明申请
    • Optical fiber for handling higher powers
    • 用于处理更高功率的光纤
    • US20050226580A1
    • 2005-10-13
    • US10820475
    • 2004-04-08
    • Bryce SamsonAdrian Carter
    • Bryce SamsonAdrian Carter
    • G02B6/024G02B6/036G02B6/10G02B6/22
    • G02B6/03622G02B6/024G02B6/0281G02B6/03611G02B6/03633G02B6/105
    • An optical fiber comprising a core having an outer region disposed about an inner region and an intensity profile having a highest intensity that is less than the highest intensity of a Gaussian intensity profile that is normalized to have the same power as the intensity profile. The outer region can comprise an index of refraction that is greater than an index of refraction comprised by the inner region. The outer region can comprise a first concentration of a selected rare earth and any concentration of the selected rare earth comprised by the inner region can be less than the selected concentration. The inner region can include first and second rare earths and the outer region can be photosensitive. A second cladding can be included. A fiber according to the invention can be birefringent and can include, for example, at least one longitudinally extending stress inducing region for creating birefringence.
    • 一种光纤,包括具有围绕内部区域设置的外部区域的核心和具有最高强度的强度分布,所述强度分布小于高斯强度分布的最高强度,该高斯强度分布被归一化以具有与强度分布相同的功率。 外部区域可以包括大于由内部区域包括的折射率的折射率。 外部区域可以包括所选稀土的第一浓度,并且由内部区域包含的所选稀土的任何浓度可以小于所选择的浓度。 内部区域可以包括第一和第二稀土,并且外部区域可以是光敏的。 可以包括第二包层。 根据本发明的纤维可以是双折射的,并且可以包括例如用于产生双折射的至少一个纵向延伸的应力诱导区域。
    • 5. 发明授权
    • Phenyl-and phenylalkyl-substituted ethanolamines and ethylenediamines
    • 苯基和苯基烷基取代的乙醇胺和乙二胺
    • US06770636B2
    • 2004-08-03
    • US09912163
    • 2001-07-24
    • Klaus FuchsWerner StranskyMatthias GrauertAdrian CarterWolfram GaidaThomas WeiserHelmut Ensinger
    • Klaus FuchsWerner StranskyMatthias GrauertAdrian CarterWolfram GaidaThomas WeiserHelmut Ensinger
    • A61K3133
    • C07D295/125C07C211/35C07C217/48C07C2601/02C07C2601/14C07C2601/16C07D231/12C07D233/56C07D249/08C07D295/092
    • Compounds of formula 1, wherein: R1 is hydrogen, hydroxy, CF3, NO2, CN, halogen, C1-C8-alkyl, or C1-C8-alkoxy; R2, R3, and R4 independently of one another are hydrogen, C1-C8-alkyl, hydroxy, NO2, CN, C1-C8-alkoxyl, CF3, or halogen; R5 and R6 independently of one another are hydrogen or a group consisting of C1-C8-alkyl, C2-C8-alkenyl, C3-C8-alkynyl, C3-C8-cycloalkyl, C3-C8-cycloalkyl-C1-C6-alkylene, C5-C8-cycloalkenyl, C5-C8-cycloalkenyl-C1-C6-alkylene, C6-C10-aryl, and C6-C10-aryl-C1-C6-alkylene, each optionally substituted by a group consisting of C1-C6-alkyl, C2-C6-alkenyl, halogen, C1-C6-alkyloxy, —NH2, —NH(C1-C4-alkyl), —N(C1-C4-alkyl)2, hydroxy, ═O, —COOH, —CO—OC1-C4-alkyl, —CONH2, —CONH(C1-C4-alkyl), —CON(C1-C4-alkyl)2, and CF3, or R5 and R6 together with the nitrogen atom are a saturated or unsaturated 5-, 6-, 7-, or 8-membered heterocyclic group optionally containing one or two further heteroatoms consisting of sulfur, oxygen, and nitrogen, and optionally mono-, di-, or trisubstituted by a group consisting of C1-C4-alkyl, hydroxy, ═O, —COOH, —CO—OC1-C4-alkyl, —CONH2, —CONH(C1-C4-alkyl), —CON(C1-C4-alkyl)2, halogen, and benzyl; X is oxygen, —NH—, —N(CHO)—, —N(CO—C1-C6-alkyl), —N(C1-C6-alkyl), or —N(C3-C6-cycloalkyl-C1-C4-alkylene); and A is a group consisting of C1-C6-alkylene, C2-C6-alkenylene, and C3-C6-alkynylene, each optionally substituted by a group consisting of halogen, ═O, and hydroxy, or an optical isomer, enantiomer, tautomer, free base, or pharmacologically acceptable acid addition salt thereof; methods of making such compounds; pharmaceutical compositions thereof, and their use in treating or preventing certain diseases.
    • 式1的化合物,其中:R 1是氢,羟基,CF 3,NO 2,CN,卤素,C 1 -C 8 - 烷基或C 1 -C 8 - 烷氧基; R 2,R 3, 4>彼此独立地是氢,C 1 -C 8 - 烷基,羟基,NO 2,CN,C 1 -C 8 - 烷氧基,CF 3或卤素; R 5和R 6彼此独立地是氢或基团 由C 1 -C 8 - 烷基,C 2 -C 8 - 烯基,C 3 -C 8 - 炔基,C 3 -C 8 - 环烷基,C 3 -C 8 - 环烷基-C 1 -C 6亚烷基,C 5 -C 8 - 环烯基,C 5 -C 8 - 环烯基 - C 1 -C 6 - 亚烷基,C 6 -C 10 - 芳基和C 6 -C 10 - 芳基-C 1 -C 6亚烷基,各自任选被C 1 -C 6 - 烷基,C 2 -C 6 - 烯基,卤素,C 1 -C 6 - 烷氧基,-NH 2,-NH(C 1 -C 4 - 烷基),-N(C 1 -C 4 - 烷基)2,羟基,= O,-COOH,-CO-OC 1 -C 4烷基,-CONH 2,-CONH C 1 -C 4烷基),-CON(C 1 -C 4 - 烷基)2和CF 3或R 5和R 6与氮原子一起为饱和或不饱和的5-,6-,7-或 任选地含有一个或两个由硫,氧和氮组成的另外的杂原子的8-元杂环基,以及任选的单 - ,二 - ,或被由C 1 -C 4 - 烷基,羟基,O,-COOH,-CO-OC 1 -C 4烷基,-CONH 2,-CONH(C 1 -C 4 - 烷基),-CON(C 1 -C 4) - 烷基)2,卤素和苄基; X是氧,-NH-,-N(CHO) - , - N(CO-C 1 -C 6烷基), - N(C 1 -C 6 - 烷基) (C 3 -C 6 - 环烷基-C 1 -C 4 - 亚烷基); 并且A是由C 1 -C 6亚烷基,C 2 -C 6亚烯基和C 3 -C 6亚炔基组成的基团,各自任选地被卤素,= O和羟基取代,或光学异构体,对映体,互变异构体, 游离碱或其药理学上可接受的酸加成盐; 制备此类化合物的方法; 其药物组合物及其在治疗或预防某些疾病中的用途。
    • 7. 发明授权
    • 1,2,3,4,5,6-Hexahydro-2,6-methano-3-benzazocin-10-ols
    • 1,2,3,4,5,6-六氢-2,6-亚甲基-3-苯并吖庚因-10-ols
    • US06455538B1
    • 2002-09-24
    • US09523473
    • 2000-03-10
    • Matthias GrauertAdrian CarterWolf-Dietrich BechtelThomas WeiserRainer PallukUwe Pschorn
    • Matthias GrauertAdrian CarterWolf-Dietrich BechtelThomas WeiserRainer PallukUwe Pschorn
    • A61K31439
    • C07D221/26
    • Compounds of general formula I wherein X is a single bond, —O—, C-C4-alkylene, or an alkylene bridge having 1 to 8 carbon atoms which may be branched or unbranched and optionally have one or two oxygen atom(s) anywhere in the bridge; R1 is hydrogen, methyl, ethyl, or phenyl; R2 is hydrogen or methyl; R3 is hydrogen, fluorine, chlorine, bromine, hydroxy, methyl, or methoxy; R4 is hydrogen, methyl, or ethyl; R5 is hydrogen, methyl, or ethyl; R6 is hydrogen, methyl, or ethyl; R7 is tert-butyl, cyclohexyl, phenyl optionally substituted by R9 and R10, which may be identical or different, or; R8 is hydrogen or C1-C4-alkyl; Z is oxygen, NH, or sulfur; R9 is hydrogen, methyl, fluorine, chlorine, bromine, or methoxy; R10 is hydrogen, methyl, fluorine, chlorine, bromine, or methoxy; optionally in the form of the individual optical isomers, mixtures of the individual enantiomers or racemates as well as in the form of the free bases or the corresponding acid addition salts with pharmaceutically acceptable acids.
    • 通式I的化合物,其中X是单键,-O-,C-C4-亚烷基或具有1至8个碳原子的亚烷基桥,其可以是支链或非支链的,并且任选地在一个或多个氧原子中具有一个或两个氧原子 桥梁 R1是氢,甲基,乙基或苯基; R2是氢或甲基; R3是氢,氟,氯,溴,羟基,甲基或甲氧基; R4是氢,甲基或乙基; R5是氢,甲基或乙基; R6是氢,甲基或乙基; R 7是叔丁基,环己基,任选被R 9和R 10取代的苯基,其可以相同或不同,或者R 8是氢或C 1 -C 4 - 烷基; Z是氧,NH或硫; R9是氢,甲基,氟,氯,溴或甲氧基; R 10为氢,甲基,氟,氯,溴或甲氧基; 任选以各种旋光异构体的形式,各个对映异构体或外消旋体的混合物,以及游离碱的形式或与药学上可接受的酸的相应的酸加成盐。
    • 10. 发明申请
    • Fiber Optic Article with Inner Region
    • 内光纤光纤产品
    • US20060198590A1
    • 2006-09-07
    • US11419907
    • 2006-05-23
    • Julia FarroniUpendra ManyamNils JacobsonKanishka TankalaAdrian Carter
    • Julia FarroniUpendra ManyamNils JacobsonKanishka TankalaAdrian Carter
    • G02B6/02
    • G02B6/024
    • A fiber optic article can comprise a core, an inner region disposed about the core and a cladding disposed about the inner region. The index of refraction of the cladding can be less than that of the inner region, and the index of refraction of the inner region can be less than that of the core. The fiber can include a second cladding disposed about the cladding, where the second cladding has an index of refraction that is less than the index of refraction of the cladding. The inner region can have a non circular outer perimeter that includes at least one inwardly oriented section. The article can be elongate along a longitudinal axis and can include at least one longitudinally extending region, such as a stress inducing region, for providing birefringence and the inwardly oriented region can face the longitudinally extending region. The fiber optic article can include active material for providing light responsive to the article receiving pump light, such as, for example, one or more rare earths. The rare earths can include erbium and ytterbium.
    • 光纤制品可以包括芯,围绕芯设置的内部区域和围绕内部区域设置的包层。 包层的折射率可以小于内部区域的折射率,并且内部区域的折射率可以小于芯部的折射率。 纤维可以包括围绕包层设置的第二包层,其中第二包层的折射率小于包层的折射率。 内部区域可以具有包括至少一个向内定向的部分的非圆形外周边。 该制品可以沿纵向轴线延伸并且可以包括至少一个纵向延伸区域,例如应力诱导区域,用于提供双折射,并且向内取向区域可面向纵向延伸区域。 光纤制品可以包括用于提供响应于物品接收泵浦光的光的活性材料,例如一个或多个稀土。 稀土可以包括铒和镱。