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1. 发明申请

WO2012067682A1 SYSTEM AND METHOD FOR PRESENTING INFORMATION REPRESENTATIVE OF LESION FORMATION IN TISSUE DURING AN ABLATION PROCEDURE 审中-公开
标题翻译：系统和方法，用于在消除程序期间呈现组织中的组织形成信息表示
公开(公告)号：WO2012067682A1
公开(公告)日：2012-05-24
申请号：PCT/US2011/047235
申请日：2011-08-10
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , AFONSO, Valtino X. , DRAGNEV, Lubomir V. , CUMMING, Sarah E. , SHAI, Yitzhak I. , PAUL, Saurav
发明人： AFONSO, Valtino X. , DRAGNEV, Lubomir V. , CUMMING, Sarah E. , SHAI, Yitzhak I. , PAUL, Saurav
IPC分类号： A61B18/00
CPC分类号： A61B18/1492 , A61B5/0402 , A61B5/042 , A61B5/7203 , A61B18/1233 , A61B18/14 , A61B18/24 , A61B34/25 , A61B2017/00128 , A61B2017/00199 , A61B2018/00178 , A61B2018/00351 , A61B2018/00357 , A61B2018/00577 , A61B2018/00648 , A61B2018/00702 , A61B2018/00714 , A61B2018/00738 , A61B2018/00779 , A61B2018/00875 , A61B2018/00892 , A61B2018/0212 , A61B2018/0262 , A61B2034/104 , A61B2034/2046 , A61B2034/2051 , A61B2034/2072 , A61B2034/301 , A61B2090/065 , A61B2218/002 , A61N7/022
摘要： A method and system 10 for presenting information representative of lesion formation is provided. The system 10 comprises an electronic control unit (ECU) 22. The ECU 22 is configured to acquire a value for an ablation description parameter and/or a position signal metric, wherein the value corresponds to a location in the tissue. The ECU 22 is further configured to evaluate the value, assign it a visual indicator of a visualization scheme associated with the parameter/metric corresponding to the value, and generate a marker comprising the visual indicator such that the marker is indicative of the acquired value. The method comprises acquiring a value for the parameter/metric, and evaluating the value. The method further includes assigning a visual indicator of a visualization scheme associated with the parameter/metric corresponding to the value, and generating a marker comprising the visual indicator.
摘要翻译：提供了一种表示病变形成信息的方法和系统10。系统10包括电子控制单元（ECU）22。ECU 22被配置为获取消融描述参数和/或位置信号度量的值，其中该值对应于组织中的位置。 ECU22进一步被配置为评估该值，为其指定与该值相对应的参数/度量相关联的可视化方案的视觉指示符，并且生成包括视觉指示符的标记，使得该标记指示所获取的值。该方法包括获取参数/度量的值并评估该值。该方法还包括分配与该值对应的参数/度量相关联的可视化方案的视觉指示符，以及生成包括视觉指示符的标记。

2. 发明申请

WO2012064818A1 ELECTROPHYSIOLOGY CATHETERS HAVING A LOOP PORTION AND METHODS OF MANUFACTURING THEREFOR 审中-公开
标题翻译：具有环形部分的电生理导管及其制造方法
公开(公告)号：WO2012064818A1
公开(公告)日：2012-05-18
申请号：PCT/US2011/059922
申请日：2011-11-09
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , AFONSO, Valtino X. , POTTER, Daniel J. , CHAN, Howard , ROY, Pianka , DE LA RAMA, Alan , VELASCO, Jennifer , CHEN, Kailing
发明人： AFONSO, Valtino X. , POTTER, Daniel J. , CHAN, Howard , ROY, Pianka , DE LA RAMA, Alan , VELASCO, Jennifer , CHEN, Kailing
IPC分类号： A61B5/042
CPC分类号： A61B5/0422 , A61B5/6856 , A61B18/1492 , A61B2017/003 , A61B2017/00323 , A61B2017/00867 , A61B2018/0016 , A61B2018/00214 , A61B2018/00351 , A61B2018/1435 , A61B2562/0209 , B23K1/0008
摘要： An electrophysiology (EP) catheter (10, 110) has a longitudinal axis (A) and includes a catheter body (12) having a proximal region (14); a neck region (18), and a distal portion (16, 116). In an embodiment, the distal portion (16) is predisposed into a loop consisting of a single, helical revolution when in a non-compressed state. An axis (a) of the single, helical revolution is offset from the longitudinal axis (A). In another embodiment, the distal portion (116) is predisposed into a plurality of loops comprising at least a first loop and a second loop when in a non-compressed state, wherein a majority of the first loop and a majority of the second loop is disposed within a common plane that is substantially perpendicular to the longitudinal axis (A). The EP catheter (10, 110) further includes a plurality of electrodes (20) coupled to the distal portion (16, 116).
摘要翻译：电生理学（EP）导管（10,110）具有纵向轴线（A）并且包括具有近端区域（14）的导管主体（12）; 颈部区域（18）和远端部分（16,116）。在一个实施例中，当处于非压缩状态时，远侧部分（16）被预先设置成由单个螺旋旋转组成的回路。单个螺旋旋转的轴线（a）偏离纵向轴线（A）。在另一个实施例中，当处于非压缩状态时，远端部分（116）被预先设置成包括至少第一环路和第二环路的多个环路，其中第一环路的大部分和第二环路的大部分是设置在基本上垂直于纵向轴线（A）的公共平面内。 EP导管（10,110）还包括耦合到远端部分（16,116）的多个电极（20）。

3. 发明申请

WO2007035306A2 SYSTEM AND METHOD FOR THREE-DIMENSIONAL MAPPING OF ELECTROPHYSIOLOGY INFORMATION 审中-公开
标题翻译：电生理信息三维映射的系统与方法
公开(公告)号：WO2007035306A2
公开(公告)日：2007-03-29
申请号：PCT/US2006/035290
申请日：2006-09-12
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , AFONSO, Valtino, X. , BELHE, Kedar, Ravindra , SCHWEITZER, Jeffrey, A.
发明人： AFONSO, Valtino, X. , BELHE, Kedar, Ravindra , SCHWEITZER, Jeffrey, A.
IPC分类号： A61B5/04
CPC分类号： A61B5/0422 , A61B5/04012 , A61B5/044 , A61B5/0452
摘要： An electrophysiology apparatus (8) is used to measure electrical activity occurring in a heart (10) of a patient (11) and to visualize the electrical activity and/or information related to the electrical activity. A three dimensional map of the electrical activity and/or the information related to the electrical activity is created. Colors, shades of colors, and/or grayscales are assigned to values of the parameters and colors corresponding to the parameters for the electrograms sampled by the electrodes (e.g., 12, 14, 16, 17, 18, 19, 22) are updated on the three dimensional model (62).
摘要翻译：电生理学装置（8）用于测量在患者（11）的心脏（10）中发生的电活动并且可视化与电活动相关的电活动和/或信息。创建电活动的三维图和/或与电活动有关的信息。将颜色，色调和/或灰度等级分配给参数的值和对应于由电极采样的电描记图（例如，12,14,16,17,18,19,22）的参数的参数的值被更新为三维模型（62）。

4. 发明申请

WO2012092016A1 SYSTEM AND METHOD FOR DIAGNOSING ARRHYTHMIAS AND DIRECTING CATHETER THERAPIES 审中-公开
标题翻译：用于诊断ARRHYTHMIAS和导管导管治疗的系统和方法
公开(公告)号：WO2012092016A1
公开(公告)日：2012-07-05
申请号：PCT/US2011/066100
申请日：2011-12-20
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , AFONSO, Valtino, X. , SHI, Jiazheng , KIM, Steven, J. , DENO, D., Curtis , MORGAN, Dennis, J.
发明人： AFONSO, Valtino, X. , SHI, Jiazheng , KIM, Steven, J. , DENO, D., Curtis , MORGAN, Dennis, J.
IPC分类号： A61B5/04
CPC分类号： A61B5/0422 , A61B5/0044 , A61B5/04017 , A61B5/044 , A61B5/0452 , A61B5/0538 , A61B5/065 , A61B5/066 , A61B5/068 , A61B5/4836 , A61B5/6852 , A61B5/6855 , A61B18/1492 , A61B34/20 , A61B34/25 , A61B2018/00577 , A61B2018/00839 , A61B2562/043 , A61B2576/023
摘要： An efficient system for diagnosing arrhythmias and directing catheter therapies may allow for measuring, classifying, analyzing, and mapping spatial electrophysiological (EP) patterns within a body. The efficient system may further guide arrhythmia therapy and update maps as treatment is delivered. The efficient system may use a medical device having a high density of sensors with a known spatial configuration for collecting EP data and positioning data. Further, the efficient system may also use an electronic control system (ECU) for computing and providing the user with a variety of metrics, derivative metrics, high definition (HD) maps, HD composite maps, and general visual aids for association with a geometrical anatomical model shown on a display device.
摘要翻译：用于诊断心律失常并引导导管治疗的有效系统可以允许测量，分类，分析和映射身体内的空间电生理（EP）模式。有效的系统可以进一步指导心律失常治疗和更新地图，因为治疗被传递。有效的系统可以使用具有已知空间配置的高密度传感器的医疗装置来收集EP数据和定位数据。此外，有效系统还可以使用电子控制系统（ECU）来计算并向用户提供各种度量，导数度量，高清晰度（HD）地图，高清复合地图以及与几何图形相关联的一般视觉辅助解剖模型显示在显示设备上。

5. 发明申请

WO2007137077A3 SYSTEM AND METHOD FOR MAPPING COMPLEX FRACTIONATED ELECTROGRAM INFORMATION 审中-公开
标题翻译：用于映射复合分解电子信息的系统和方法
公开(公告)号：WO2007137077A3
公开(公告)日：2008-06-19
申请号：PCT/US2007069055
申请日：2007-05-16
申请人： ST JUDE MEDICAL ATRIAL FIBRILL , AFONSO VALTINO X
发明人： AFONSO VALTINO X
IPC分类号： A61B5/0402
CPC分类号： A61B5/04012 , A61B5/0422 , A61B5/044
摘要： A system 8 for presenting information representative of patient electrophysiological activity, such as complex fractionated electrogram information, includes at least one electrode to measure electrogram information from the heart surface, at least one processor coupled to the at least one electrode 17 to receive the electrogram information and measure a location of the at least one electrode 17 within the heart 10, and a presentation device 23 to present the electrogram information as associated with the location at which it was measured on a model of the patient's heart. A memory may also be provided in which to store the associated electrogram information and measured location. Data may be analyzed using both time-domain and frequency-domain information to create a three-dimensional map. The map displays the data as colors, shades of color, and/or grayscales, and may further utilize contour lines, such as isochrones, to present the information.
摘要翻译：用于呈现表示患者电生理活动的信息的系统8，例如复杂分级电描记图信息，包括至少一个电极，用于测量来自心脏表面的电描记图信息;耦合到至少一个电极17的至少一个处理器，以接收电描记图信息并且测量心脏10内的至少一个电极17的位置，以及呈现装置23，以呈现与在患者心脏的模型上测量的位置相关联的电描记图信息。还可以提供存储器，用于存储相关联的电描记图信息和测量位置。可以使用时域和频域信息来分析数据以创建三维地图。地图将数据显示为颜色，色调和/或灰度等级，并且可以进一步利用诸如等时线的等高线来呈现信息。

6. 发明申请

WO2012047374A1 METHOD AND SYSTEM FOR IDENTIFYING CARDIAC ARRHYTHMIA DRIVER SITES 审中-公开
标题翻译：用于识别心脏病患者的方法和系统
公开(公告)号：WO2012047374A1
公开(公告)日：2012-04-12
申请号：PCT/US2011/047234
申请日：2011-08-10
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , RYU, Kyungmoo , AFONSO, Valtino X.
发明人： RYU, Kyungmoo , AFONSO, Valtino X.
IPC分类号： A61N1/00
CPC分类号： A61B5/0452 , A61B5/046 , A61N1/3624
摘要： A method of identifying potential driver sites for cardiac arrhythmias includes acquiring a plurality of electrograms from a plurality of locations on at least a portion of a patient's heart (10). Using the acquired electrograms, at least one electrical activity map is generated. Desirable electrical activity maps include complex fractionated electrogram standard deviation and mean maps, dominant frequency maps, peak-to-peak voltage maps, and activation sequence maps. Using one or more of these maps (e.g., by analyzing one or more electrogram morphological characteristics represented by these maps), at least one potential driver site can be detected.
摘要翻译：识别用于心律失常的潜在驾驶员位置的方法包括从患者心脏（10）的至少一部分上的多个位置获取多个电描记图。使用所获取的电描记图，生成至少一个电活动图。期望的电活动图包括复杂的分级电描记图标准偏差和平均图，主要频率图，峰 - 峰电压图和激活序列图。使用这些图中的一个或多个（例如，通过分析由这些图表示的一个或多个电描记图形态特征），可以检测至少一个潜在的驾驶员地点。

7. 发明申请

WO2007137077A2 SYSTEM AND METHOD FOR MAPPING COMPLEX FRACTIONATED ELECTROGRAM INFORMATION 审中-公开
标题翻译：用于映射复合分解电子信息的系统和方法
公开(公告)号：WO2007137077A2
公开(公告)日：2007-11-29
申请号：PCT/US2007/069055
申请日：2007-05-16
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , AFONSO, Valtino X.
发明人： AFONSO, Valtino X.
IPC分类号： A61B5/02
CPC分类号： A61B5/04012 , A61B5/0422 , A61B5/044 , G06F19/00
摘要： A system 8 for presenting information representative of patient electrophysiological activity, such as complex fractionated electrogram information, includes at least one electrode to measure electrogram information from the heart surface, at least one processor coupled to the at least one electrode 17 to receive the electrogram information and measure a location of the at least one electrode 17 within the heart 10, and a presentation device 23 to present the electrogram information as associated with the location at which it was measured on a model of the patient's heart. A memory may also be provided in which to store the associated electrogram information and measured location. Data may be analyzed using both time-domain and frequency-domain information to create a three-dimensional map. The map displays the data as colors, shades of color, and/or grayscales, and may further utilize contour lines, such as isochrones, to present the information.
摘要翻译：用于呈现表示患者电生理活动的信息的系统8，例如复杂分级电描记图信息，包括至少一个电极，用于测量来自心脏表面的电描记图信息，耦合到至少一个电极17的至少一个处理器，以接收电描记图信息并且测量心脏10内的至少一个电极17的位置，以及呈现装置23，以呈现与在患者心脏的模型上测量的位置相关联的电描记图信息。还可以提供存储相关电描记图信息和测量位置的存储器。可以使用时域和频域信息来分析数据以创建三维地图。该地图将数据显示为颜色，色调和/或灰度等级，并且可以进一步利用诸如等时线的等值线来呈现信息。

8. 发明申请

WO2007035306A3 SYSTEM AND METHOD FOR THREE-DIMENSIONAL MAPPING OF ELECTROPHYSIOLOGY INFORMATION 审中-公开
标题翻译：用于电子生物学信息的三维映射的系统和方法
公开(公告)号：WO2007035306A3
公开(公告)日：2007-06-28
申请号：PCT/US2006035290
申请日：2006-09-12
申请人： ST JUDE MEDICAL ATRIAL FIBRILL , AFONSO VALTINO X , BELHE KEDAR RAVINDRA , SCHWEITZER JEFFREY A
发明人： AFONSO VALTINO X , BELHE KEDAR RAVINDRA , SCHWEITZER JEFFREY A
IPC分类号： A61B5/04
CPC分类号： A61B5/0422 , A61B5/04012 , A61B5/044 , A61B5/0452
摘要： An electrophysiology apparatus (8) is used to measure electrical activity occurring in a heart (10) of a patient (11) and to visualize the electrical activity and/or information related to the electrical activity. A three dimensional map of the electrical activity and/or the information related to the electrical activity is created. Colors, shades of colors, and/or grayscales are assigned to values of the parameters and colors corresponding to the parameters for the electrograms sampled by the electrodes (e.g., 12, 14, 16, 17, 18, 19, 22) are updated on the three dimensional model (62).
摘要翻译：使用电生理学设备（8）来测量在患者（11）的心脏（10）中发生的电活动并且显现与电活动有关的电活动和/或信息。创建电活动的三维图和/或与电活动相关的信息。将颜色，颜色阴影和/或灰度分配给与由电极（例如，12,14,16,17,18,19,22）采样的电描记图的参数对应的参数和颜色的值被更新三维模型（62）。

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