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1. 发明专利

JP2003000233A Method for proliferating cell 审中-公开
标题翻译：促进细胞的方法
公开(公告)号：JP2003000233A
公开(公告)日：2003-01-07
申请号：JP2001234224
申请日：2001-06-19
申请人： Kazumi Asami , Masao Shimizu , Isao Shimozaki , Akira Takeuchi , 勇生下崎 , 和己浅見 , 正雄清水 , 晃竹内
发明人： SHIMOZAKI ISAO , TAKEUCHI AKIRA , ASAMI KAZUMI , SHIMIZU MASAO
IPC分类号： A61L27/00 , C12N5/07 , C12N5/077 , C12N5/06
摘要： PROBLEM TO BE SOLVED: To provide a method for efficiently proliferating cells through the activation of proliferation potency thereof by imparting thermal stimulation to epithelial cells or interstitial cells. SOLUTION: The thermal stimulation is imparted to the cell to activate the decomposition and reconstruction of collagen and enhance the remodeling function of the extracellular matrix and resultantly to prorate the physiological proliferation reactions of the cells.
摘要翻译：要解决的问题：提供通过对上皮细胞或间质细胞施加热刺激，通过其增殖效力的活化来有效增殖细胞的方法。解决方案：将热刺激赋予细胞以激活胶原蛋白的分解和重建，并增强细胞外基质的重塑功能，从而分化细胞的生理增殖反应。

2. 发明专利

JP2003000231A Method for proliferating normal cell 审中-公开
标题翻译：促进正常细胞的方法
公开(公告)号：JP2003000231A
公开(公告)日：2003-01-07
申请号：JP2001225186
申请日：2001-06-20
申请人： Kazumi Asami , Masao Shimizu , Isao Shimozaki , Akira Takeuchi , 勇生下崎 , 和己浅見 , 正雄清水 , 晃竹内
发明人： SHIMOZAKI ISAO , TAKEUCHI AKIRA , ASAMI KAZUMI , SHIMIZU MASAO
IPC分类号： C12N5/07 , C12N5/077 , C12N5/09 , C12N5/06
摘要： PROBLEM TO BE SOLVED: To provide a method for proliferating only normal cells through a p53 gene by imparting thermal stimulation to epithelial cells or interstitial cells. SOLUTION: Cells are confirmed to have the p53 gene, then they are thermally stimulated so that a heat shock protein may be expressed and the p53 gene is activated whereby the apoptosis of abnormal cells that are apt to cause canceration are induced and the proliferation of only normal cells are promoted.
摘要翻译：要解决的问题：提供通过对上皮细胞或间质细胞赋予热刺激而仅通过p53基因增殖正常细胞的方法。解决方案：确认细胞具有p53基因，然后对其进行热刺激，从而可以表达热休克蛋白，并激活p53基因，从而诱导易于引起癌变的异常细胞的凋亡，仅增殖促进正常细胞。

3. 发明专利

JP2006167387A Body temperature controlling apparatus 审中-公开
标题翻译：身体温度控制装置
公开(公告)号：JP2006167387A
公开(公告)日：2006-06-29
申请号：JP2004382506
申请日：2004-12-13
申请人： Blast Co Ltd , Luke Hospital , Isao Shimozaki , Akira Takeuchi , 勇生下崎 , 医療法人社団ルーク会 , 株式会社ブラスト , 晃竹内
发明人： SHIMOZAKI ISAO , TAKEUCHI AKIRA
IPC分类号： A61F7/00 , A01K13/00 , A61B5/01 , A61F7/08 , A61N5/06
摘要： PROBLEM TO BE SOLVED: To provide a body temperature controlling apparatus which mathematically, minutely and continuously gets hold of a heat transfer situation of an animal or the human body wherein the heat is hardly transferred to a central portion and the temperature autonomously changes, increases the deep temperature in a wide range by optimizing a heating efficiency and maintains the temperature in a certain range.
SOLUTION: The body temperature controlling apparatus is equipped with heating means 1a-e to cover the whole of the human body lower than the neck, and several fans 2a-f at various places to ventilate the inside, and executes the heating or the temperature control of the deep part of the human body by acquiring a heating period of the resonance of the surface and the deep on the basis of an FFT analysis of the body temperature and periodically changing the heating amount by the ON-OFF operation of the heating means with the same period and the same or the opposite phase.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：提供一种体温控制装置，其在数学上，微妙且连续地获得动物或人体的热传递状态，其中热几乎不传递到中心部分，并且温度自主地改变，通过优化加热效率并将温度保持在一定范围内，在较宽的范围内增加深度温度。解决方案：体温控制装置配备有加热装置1a-e以覆盖比颈部低的人体整体，以及多个风扇2a-f，用于对内部进行通风，并执行加热或通过基于体温的FFT分析获取表面和深度的共振的加热期，并通过对体温的ON-OFF动作周期性地变更加热量来进行人体深部的温度控制加热装置具有相同的周期和相同或相反的相位。版权所有（C）2006，JPO＆NCIPI

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