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    • 3. 发明专利
    • Food formulated with fat-soluble effective component
    • 食用脂肪可溶性有效成分
    • JP2005143365A
    • 2005-06-09
    • JP2003384204
    • 2003-11-13
    • Hiroyuki IjimaToshihiro NomuraTomoaki Takeda弘之 井島知晶 武田俊博 野村
    • NOMURA TOSHIHIROIJIMA HIROYUKITAKEDA TOMOAKI
    • A23L1/30A23L1/00A61K9/48A61K35/50A61K38/43A61P3/00
    • PROBLEM TO BE SOLVED: To obtain a food enabling efficiently absorbing CoQ 10 from the oral mucous membrane. SOLUTION: The food 5 formulated with CoQ 10 is obtained by forming CoQ 10 containing-agar capsules 3 through including in agar capsule films 2 CoQ 10 containing oil liquid 1 obtained by dissolving CoQ 10 in a medium chain triglyceride, adding CoQ 10 containing agar capsules 3 to a food 4 formulated with placenta essence, heat-sterilizing the food, and cooling followed by homogeneously mixing. Since the food 5 formulated with the placenta essence attaches to the oral mucous membrane by its viscosity, the food makes the CoQ 10 containing-agar capsules 3 together stay for a long time in the mouth, and in this condition, the CoQ 10 -containing oil liquid 1 in the CoQ 10 containing-agar capsules 3 is emitted by chewing or crushing by the tongue so as to attache CoQ 10 together with the medium chain triglyceride to the oral mucous membrane. COPYRIGHT: (C)2005,JPO&NCIPI
    • 要解决的问题:获得能够从口腔粘膜有效吸收CoQ 10 的食物。 解决方案:通过在琼脂胶囊膜2 CoQ 10中包含含有琼脂胶囊3的含CoQ SB 10 10 SBB,获得配制有CoQ <10> 的食品5, / SB>含有油性液体1,其通过将CoQ 10 溶解在中链甘油三酯中,将含有琼脂胶囊3的CoQ <10> / SB>添加到配制有胎盘精华的食物4中, 对食物进行灭菌,然后冷却,然后均匀混合。 由于用胎盘精华配制的食物5通过其粘度附着在口腔粘膜上,所以食物使含有琼脂胶囊3的CoQ <10> 一起在口中保持很长时间, 在含有琼脂胶囊3的CoQ <10> / SB> 10 含油脂液体1中,通过舌头的咀嚼或粉碎来排出,以便粘附CoQ 10S与中链甘油三酯连同口服粘膜。 版权所有(C)2005,JPO&NCIPI
    • 4. 发明专利
    • Enzyme-compounded granule acting in intestine, and enzyme-compounded food using the enzyme-compounded granule
    • 在酵素中使用酶复合颗粒饲料,以及使用酶复合颗粒的酶复合食品
    • JP2008109910A
    • 2008-05-15
    • JP2006296290
    • 2006-10-31
    • Hiroyuki IjimaToshihiro NomuraTomoaki Takeda弘之 井島知晶 武田俊博 野村
    • NOMURA TOSHIHIROIJIMA HIROYUKITAKEDA TOMOAKI
    • A23L1/30A23L1/00A61K9/16A61K9/48A61K47/42A61K47/44
    • PROBLEM TO BE SOLVED: To make an enzyme and an enteric substance to arrive at an intestine without being exposed to a gastric juice. SOLUTION: An oil liquid 2 containing CoQ 10 of enteric substance is encapsulated with a gelatin coating film 3 to form a seamless nucleus 1, and an enzyme-containing coating film 4 is disposed on the surface of the seamless nucleus 1 to form an enzyme-compounded granule 5. The enzyme-compounded granules 5 are charged and sealed in a hard capsule 6, and the whole surface of the capsule is coated with zein 7 to form an enzyme-compounded food 8. When the enzyme-compounded food 8 is drunk, the enzyme-compounded food 8 arrives at the intestine through a stomach without being dissolved in a gastric juice due to the existence of the coating layer of the zein 7. The coating layer of the zein 7, and the hard capsule 6 are sequentially collapsed in the intestine, and the enzyme compounded in the enzyme-containing coating films 4 of the enzyme-compounded granules 5 are released in the intestine. The gelatin coating films 3 of the seamless nuclei 1 exposed by the collapse of the coating films 4 are collapsed to release the oil liquid 2 containing the CoQ 10 in the intestine. COPYRIGHT: (C)2008,JPO&INPIT
    • 要解决的问题:使酶和肠道物质到达肠道而不暴露于胃液。

      解决方案:含有肠溶物质的CoQ 10 的油液2用明胶涂膜3包封以形成无缝核1,并且在表面上设置含酶的涂膜4 的无缝核1以形成酶复合颗粒5.将酶组合的颗粒5装入并密封在硬胶囊6中,并将胶囊的整个表面涂覆有玉米醇溶蛋白7以形成酶复合食品8 当酶复合食物8被饮用时,由于玉米醇溶蛋白7的涂层的存在,酶复合食物8通过胃而不会溶解在胃液中而到达肠道。玉米蛋白的包衣层 如图7所示,硬胶囊6在肠中依次塌陷,并且在酶组合颗粒5的含酶涂膜4中复合的酶在肠中释放。 通过涂膜4的塌陷暴露出的无缝核1的明胶被膜3被塌缩,从而将含有CoQ 10 的油液2释放到肠内。 版权所有(C)2008,JPO&INPIT