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1. 发明申请

WO2021149974A1 MICRO-SPICULE COMPOSITION TO CONTROL ITS SHAPE AND METHOD FOR PRODUCING THE SAME 审中-公开
公开(公告)号：WO2021149974A1
公开(公告)日：2021-07-29
申请号：PCT/KR2021/000567
申请日：2021-01-14
申请人： PAEAN AESTHETICS INC.
发明人： HAN, Kyuboem , HA, Jongcheon
IPC分类号： A61K8/02 , A61K8/73 , A61K8/34 , A61Q19/00
摘要： A composition for controlling the shape of the micro-spicule particles, micro-spicule particles molded by water-soluble materials, and its method for producing the microspicule particles molding with water-soluble materials having a sharp pointed vertex without tip collapse by controlling the amount of the alkylated glycerin compound in the solution loaded onto the multiple pattern engraved mold. The shape of molded micro-spicules can be controlled by using alkylated glycerin and thus various types of water-soluble micro-spicule particles can be prepared when mixed with a non-aqueous formulation and applied to the skin, the water-soluble micro-spicule particles prepared by the present invention provide advantageous scrubbing effect.

2. 发明申请

WO2008140230A1 PROCESS FOR IDENTIFICATION OF KINASE SUBSTRATE SPECIFICITY BY USING PEPTIDE LIBRARY 审中-公开
标题翻译：通过使用肽库来识别激酶底物特异性的方法
公开(公告)号：WO2008140230A1
公开(公告)日：2008-11-20
申请号：PCT/KR2008/002632
申请日：2008-05-09
申请人： SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION , LEE, Yoon-Sik , KIM, Byung-Gee , KIM, Eun-Mi , SHIN, Dong-Sik , KIM, Yun Gon , KIM, Mira
发明人： LEE, Yoon-Sik , KIM, Byung-Gee , KIM, Eun-Mi , SHIN, Dong-Sik , KIM, Yun Gon , KIM, Mira
IPC分类号： C12Q1/00
CPC分类号： C12Q1/485 , C07K1/047 , G01N2333/9121
摘要： The present invention relates to a process for the identification of a kinase substrate specificity by using a peptide library. More particulary, the present invention is directed to a process for indent ifying a kinase substrate specificity, comprising: i ) linking a plurality of peptides, having a same amino acid sequence, to the surface of a solid support resin to obtain a peptide library which has peptides, with the same amino acid sequence, on the surface of the solid support resin; ii) repeating the step i ) with changing the amino acid sequence to give a random mixture of peptide libraries, wherein each solid suppot resin has peptides with a same amino acid sequence, however the amino acid sequence liked to each solid support is different from one another," iii) phosphorylating selectively a specific amino acid of a peptide which has a certain amino acid sequence by reacting the random mixture of the peptide libraries with a kinase, to give a phosphorylated peptide library; iv) reacting the phosphorylated peptide library with an antibody which is conjugated with one of a phosphatase and a peroxidase and binds selectively to a phosphorylated amino acid, followed by the addition of a substrate selectively acting on the thus prepared reaction mixture; v) selecting a solid support resin which has a peptide library of which property has been changed, by detecting the change of property due to the reaction of the sbustrate with one of the phosphatase and the peroxidase; and vi) separating a peptide from the selected solid support resin followed by analysing a sequece of the separated peptide.
摘要翻译：本发明涉及通过使用肽文库鉴定激酶底物特异性的方法。更具体地，本发明涉及一种用于缩进激酶底物特异性的方法，其包括：i）将具有相同氨基酸序列的多个肽连接到固体支持树脂的表面，以获得肽文库，在固体支持树脂的表面上具有相同氨基酸序列的肽; ii）通过改变氨基酸序列来重复步骤i），得到肽文库的无规混合物，其中每个固体支素树脂具有相同氨基酸序列的肽，然而对于每种固体支持物所喜欢的氨基酸序列不同于另一个，“iii）通过使肽文库的无规混合物与激酶反应，使具有特定氨基酸序列的肽的特定氨基酸磷酸化，得到磷酸化肽文库; iv）使磷酸化肽文库与抗体，其与磷酸酶和过氧化物酶之一缀合，并且与磷酸化氨基酸选择性结合，然后加入选择性地作用在如此制备的反应混合物上的底物; v）选择固体支持树脂，其具有肽文库通过检测由于sbustrate与磷酸酶和过氧化物之一的反应引起的性质变化，该性质已经改变 Ë; 和vi）从所选择的固体支持树脂中分离肽，然后分析分离的肽的片段。

3. 发明申请

WO2008136644A2 APPARATUS AND METHOD FOR RECOGNIZING SUBCUTANEOUS VEIN PATTERN 审中-公开
标题翻译：用于识别皮下静脉图案的装置和方法
公开(公告)号：WO2008136644A2
公开(公告)日：2008-11-13
申请号：PCT/KR2008/002571
申请日：2008-05-07
申请人： INNOZEST Inc. , SEO, Keunjoo
发明人： SEO, Keunjoo
IPC分类号： A61B5/02
CPC分类号： A61B5/0059 , A61B5/489
摘要： The present invention relates to an apparatus and a method for recognizing a subcutaneous vein pattern. More particularly, the present invention is directed to an apparatus for recognizing a subcutaneous vein pattern comprising: a light illuminator having an NIR (near infrared light) emitting device; an image acquisitor having a lenz and an image sensor which converts light reflected from subcutaneous vein into an image signal; a microprocessor which adjusts an illuminating intensity of the light illuminator and a light receiving sensitivity of the image acquisitor according to an illuminance estimated from the image signal; and a displayer which display image signals received from the microprocessor.
摘要翻译：用于识别皮下静脉图案的设备和方法技术领域本发明涉及一种用于识别皮下静脉图案的设备和方法。更具体地，本发明涉及一种用于识别皮下静脉图案的设备，其包括：具有NIR（近红外光）发射装置的光照明器; 具有lenz和图像传感器的图像获取器，其将从皮下静脉反射的光转换为图像信号; 微处理器，其根据从所述图像信号估计的照度来调整所述光照射器的照射强度和所述图像获取器的光接收灵敏度; 以及显示从微处理器接收的图像信号的显示器。

4. 发明申请

WO2006009346A2 NOVEL PROCESS FOR PREPARATION OF 2,6-DIALKYLTETRALIN 审中-公开
标题翻译：制备2,6-DIALKYLTETRALIN的新方法
公开(公告)号：WO2006009346A2
公开(公告)日：2006-01-26
申请号：PCT/KR2005/000507
申请日：2005-02-23
申请人： SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION
发明人： KIM, Young Gyu , KIM, Woon Ki , KIM, Byung Hyun , LEE, Jong Gil
CPC分类号： C07C29/17 , C07C1/24 , C07C5/367 , C07C13/48 , C07C15/24 , C07C29/141 , C07C29/32 , C07C33/20 , C07C2521/02 , C07C2521/06 , C07C2527/054 , C07C2527/08 , C07C2527/11 , C07C2527/1206 , C07C2527/128 , C07C2527/135 , C07C2527/138 , C07C2527/173 , C07C2531/08 , C07C2602/10 , C07C33/30
摘要： The present invention provides a novel method for highly selective preparation of 2,6-dialkyltetralin, a key precursor for 2,6-dimethylnaphthalene (2,6-DMN), which does not require an extra step for purifying various isomers obtained from the conventional processes for 2,6-DMN. The invention is advantageous to improve the synthetic yield, to simplify the operation and thus to reduce the cost, since different starting materials and different pathways are exploited and thus the additional steps are not necessary.
摘要翻译：本发明提供了一种用于高选择性制备2,6-二烷基四氢萘酚的新方法，2,6-二烷基四烯是2,6-二甲基萘（2,6-DMN）的关键前体，其不需要额外的步骤来纯化由常规 2,6-DMN的过程。本发明有利于提高合成产率，简化操作并因此降低成本，因为不同的起始材料和不同的途径被利用，因此不需要额外的步骤。

5. 发明申请

WO2009123383A1 APPARATUS AND METHOD FOR BLOCKING OUTFLOW OF FLUID FROM A DAMAGED SHIP 审中-公开
标题翻译：用于阻塞流体从损坏的船舶流出的装置和方法
公开(公告)号：WO2009123383A1
公开(公告)日：2009-10-08
申请号：PCT/KR2008/006040
申请日：2008-10-14
申请人： SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION , KIM, Yong Hyup , KIM, Wal Jun , KANG, Tae June , KIM, Seong Jun , LEE, Seung Min , JANG, Eui Yun , IM, Hyeong Wook , KIM, Taewoo , SEO, Dong Kyun
发明人： KIM, Yong Hyup , KIM, Wal Jun , KANG, Tae June , KIM, Seong Jun , LEE, Seung Min , JANG, Eui Yun , IM, Hyeong Wook , KIM, Taewoo , SEO, Dong Kyun
IPC分类号： B63B43/04
CPC分类号： B63B25/082 , B63B43/16
摘要： The present invention relates to an apparatus and method for blocking outflow of fluid from a damaged ship. Particularly, the present invention is directed to an apparatus for blocking outflow of fluid from a damaged ship, comprising a contractible and inflatable balloon of which inflation diameter is larger than a maximum diameter of a damaged hull, a conduit consisting of a rigid conduit and a flexible conduit, through which a filler is charged into or discharged from said balloon, wherein said rigid conduit is connected to said balloon and a method for blocking outflow of fluid from a damaged ship.
摘要翻译：本发明涉及一种用于阻止流体从受损船舶流出的装置和方法。特别地，本发明涉及一种用于阻止流体从受损船舶流出的装置，其包括充气直径大于损坏船体的最大直径的可收缩和可膨胀气囊，由刚性导管和柔性导管，填充物通过该导管填充入或从所述气球排出，其中所述刚性导管连接到所述气囊，以及阻止流体从受损船舶流出的方法。

6. 发明申请

WO2008093999A1 MRI T1 CONTRASTING AGENT COMPRISING MANGANESE OXIDE NANOPARTICLE 审中-公开
标题翻译： MRI T1对比剂包含锰氧化物纳米颗粒
公开(公告)号：WO2008093999A1
公开(公告)日：2008-08-07
申请号：PCT/KR2008/000574
申请日：2008-01-30
申请人： SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION , HYEON, Taeghwan , AN, Kwangjin , NA, Hyon Bin , LEE, Junghee
发明人： HYEON, Taeghwan , AN, Kwangjin , NA, Hyon Bin , LEE, Junghee
IPC分类号： A61K49/08
CPC分类号： A61K49/08 , A61K49/126 , A61K49/1854 , A61K49/1857 , A61K49/186 , A61K49/1863 , B82Y5/00 , Y10T428/2982
摘要： The present invention relates to the use of and method for using MnO nanoparticles as MRI Tl contrasting agents which reduces Tl of tissue. More specifically, the present invention is directed to MRI Tl contrasting agent comprising MnO nanoparticle coated with a biocompatible material bound to a biologically active material such as a targeting agent, for example tumor marker etc., and methods for diagnosis and treatment of tumor etc. using said MRI Tl contrasting agent, thereby obtaining more detailed images than the conventional MRI Tl-weighted images. The MRI Tl contrasting agent of the present invention allows a high resolution anotomic imaging by emphasizing Tl contrast images between tissues based on the difference of accumulation of the contarsting agent in tissues. Also, the MRI Tl contrasting agent of the present invention enables to visualize cellular distibution due to its high intracellular uptake. The MRI Tl contrasting agent of the present invention can be used for target-specific diagnosis and treatment of various diseases such as tumor etc. when targeting agents binding to disease- specific biomarkers are conjugated to the surface of nanoparticles.
摘要翻译：本发明涉及使用MnO纳米颗粒作为降低组织T1的MRI T1对比剂的用途和方法。更具体地，本发明涉及包含结合生物活性物质如靶向剂例如肿瘤标志物等的生物相容性材料的MnO纳米颗粒的MRI Tl造影剂，以及用于诊断和治疗肿瘤等的方法。使用所述MRI T1对比剂，从而获得比常规MRI T1加权图像更详细的图像。本发明的MRI T1造影剂基于组织中对比剂的积累差异，通过强调组织之间的T1对比度图像，可以进行高分辨率的插入成像。此外，本发明的MRI T1对比剂能够由于其高细胞内摄取而可视化细胞分布。当与疾病特异性生物标志物结合的靶向剂与纳米颗粒的表面缀合时，本发明的MRI Tl造影剂可用于靶向特异性诊断和治疗各种疾病如肿瘤等。

7. 发明申请

WO2008047966A2 METHOD FOR ENHANCING GLYCOSYLATION OF RECOMBINANT PROTEIN 审中-公开
标题翻译：用于增强重组蛋白质糖蛋白的方法
公开(公告)号：WO2008047966A2
公开(公告)日：2008-04-24
申请号：PCT/KR2006/004523
申请日：2006-11-01
申请人： HANSON BIOTECH CO., LTD , PARK, Tai Hyun , CHOI, Shin Sik , PARK, Ju Hyun
发明人： PARK, Tai Hyun , CHOI, Shin Sik , PARK, Ju Hyun
IPC分类号： C07K14/59
CPC分类号： C07K14/00 , C12N2510/02

8. 发明申请

WO2007055522A1 NOVEL DRUM EDUTAINMENT APPARATUS 审中-公开
标题翻译：新款DRUM EDUTATIONMENT APPARATUS
公开(公告)号：WO2007055522A1
公开(公告)日：2007-05-18
申请号：PCT/KR2006/004685
申请日：2006-11-09
申请人： DOOGI DOOGI DRM CO., LTD. , CHA, Young-gyoon , CHA, Young-choun
发明人： CHA, Young-gyoon , CHA, Young-choun
IPC分类号： G10D13/00
CPC分类号： G10H1/368 , G10H2210/091 , G10H2220/011 , G10H2220/015 , G10H2220/135
摘要： The present invention relates to an educational entertainment apparatus including a singing guidance unit, which comprises drum instrument set comprising snare, base, tomtom and hihat; a storage unit for musical scores for playing said drum instrument set; a monitor for displaying musical scores; a sensor for the detection of the beating motion of said drum instrument set; an input unit for inputting a singing voice for the operation of the function of said singing guidance unit; a storage unit for storing the information of lyrics and accompaniments for the operation of said singing guidance unit; a mixer for mixing sound sources; a speaker for the operation of said singing guidance unit; an accounting unit which accounts coin or paper money inserted thereto; a control box; a monitor for singing; a keyboard for inputing signals for the operation of said singing guidance unit; a soundproof housing for shielding sounds; a recording unit; and network interface card, more particularly, is directed to an music educational entertainment apparatus for allowing players to play drum instrument set according to the accompaniments displayed on the monitor for playing, to become proficient in playing based on the evaluation of the accuracy and proficiency of playing improved by means of the function of the sensor for the detection of motion, and to sing a song according to the accompaniments and lyrics through the input unit for inputting a singing voice.
摘要翻译：本发明涉及一种包括歌唱引导单元的教育娱乐设备，该歌唱引导单元包括包括圈套，基座，竖琴和高音的鼓乐器组; 用于播放所述鼓乐器组的乐谱的存储单元; 用于显示乐谱的监视器; 用于检测所述鼓乐器组的跳动运动的传感器; 输入单元，用于输入用于操作所述歌唱导引单元的功能的歌声; 存储单元，用于存储用于所述歌唱导引单元的操作的歌词和伴奏的信息; 用于混合声源的混音器; 用于操作所述唱歌指导单元的扬声器; 记帐插入硬币或纸币的会计单位; 一个控制箱一个唱歌监视器; 用于输入用于所述歌唱导引单元的操作的信号的键盘; 用于屏蔽声音的隔音外壳; 记录单元; 更具体地，涉及一种音乐教育娱乐装置，用于允许玩家根据显示在显示器上的伴奏播放鼓乐器进行播放，以基于对准确性和熟练程度的评估而熟练地播放通过用于检测运动的传感器的功能进行改进，并且通过输入单元根据伴奏和歌词来唱歌以输入歌唱声音。

9. 发明申请

WO2004088291A1 REAL-TIME MONITORING APPARATUS FOR BIOCHEMICAL REACTION 审中-公开
标题翻译：生物化学反应实时监测装置
公开(公告)号：WO2004088291A1
公开(公告)日：2004-10-14
申请号：PCT/KR2004/000785
申请日：2004-04-03
申请人： BIONEER CORPORATION , BAEK, Jong-Soo , CHO, Dong-Yeon , PARK, Hanee , PARK, Han-Oh
发明人： BAEK, Jong-Soo , CHO, Dong-Yeon , PARK, Hanee , PARK, Han-Oh
IPC分类号： G01N21/84
CPC分类号： G01N21/0332 , B01L7/52 , G01N21/6452 , G01N2021/6484
摘要： The present invention relates to an apparatus for real-time monitoring chemical reaction between various biomaterials. More particularly, the present invention directed to a real-time monitoring apparatus for biochemical reaction, which comprises parabolic mirror and/or an optical waveguide tube for effective irradiation of light over the whole plate with uniform intensity.
摘要翻译：本发明涉及用于实时监测各种生物材料之间的化学反应的装置。更具体地，本发明涉及一种用于生化反应的实时监测装置，其包括用于在整个板上均匀强度地有效照射光的抛物面镜和/或光波导管。

10. 发明申请

WO2009128596A1 APPARATUS AND METHOD FOR CONTENTS TRANSMISSION AT ADAPTIVE VARIABLE SPEEDS 审中-公开
标题翻译：用于适应变化速度传输的装置和方法
公开(公告)号：WO2009128596A1
公开(公告)日：2009-10-22
申请号：PCT/KR2008/005749
申请日：2008-09-30
申请人： CASTIS CO., LTD. , KIM, Seung-hak
发明人： KIM, Seung-hak
IPC分类号： G06Q50/00
CPC分类号： H04L5/1446 , Y02D50/10
摘要： The present invention relates to an apparatus and method for contents transmission at adaptive variable speeds. Particularly, the present invention is directed to an apparatus for contents transmission at adaptive variable speeds, which comprises means for adjusting a contents transmission speed and means for transmitting contents, wherein said means for adjusting a contents transmission speed determines an optimal transmission speed and requests said means for transmitting contents to transmit the contents at the optimal transmission speed, wherein said means for transmitting contents transmits the contents at the optimal transmission speed determined by said means for adjusting contents transmission speed; and a method for contents transmission at adaptive variable speeds.
摘要翻译：本发明涉及一种适应变速内容传输的装置和方法。特别地，本发明涉及一种用于以自适应变速的内容传输的装置，其包括用于调整内容传输速度的装置和用于发送内容的装置，其中所述用于调整内容传输速度的装置确定最佳传输速度并请求所述用于以最佳传输速度发送内容以发送内容的装置，其中所述用于发送内容的装置以由所述用于调整内容传输速度的装置确定的最佳传输速度发送内容; 以及以适应变速的内容传输的方法。

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