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1. 发明申请

WO2009148829A3 METHOD FOR TREATING HYDROCARBON-BEARING FORMATIONS WITH FLUORINATED EPOXIDES 审中-公开
公开(公告)号：WO2009148829A3
公开(公告)日：2009-12-10
申请号：PCT/US2009/044662
申请日：2009-05-20
申请人： BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM , 3M INNOVATIVE PROPERTIES COMPANY , SHARMA, Mukul, M. , POPE, Gary, A. , MARTIN, Steve , DAMS, Rudolf, J. , QIU, Zai-Ming
发明人： SHARMA, Mukul, M. , POPE, Gary, A. , MARTIN, Steve , DAMS, Rudolf, J. , QIU, Zai-Ming
IPC分类号： C09K8/00 , C09K8/035
摘要： A method of treating a hydrocarbon-bearing formation with a fluorinated epoxide and a treated hydrocarbon-bearing formation. A method of making proppants is also disclosed, which includes combining a plurality of particles with a fluorinated epoxide. The particles comprise at least one of sand, resin-coated sand, ceramic, thermoplastic, clay, bauxite, nut or seed shells, fruit pits, or wood. A particle treated with a ring-opened product of a fluorinated epoxide is also disclosed, wherein the particle comprises one of sand, resin-coated sand, ceramic, thermoplastic, clay, bauxite, nut or seed shells, fruit pits, or wood.

2. 发明申请

WO2009018358A2 DEVICE FOR THE MODULATION OF CARDIAC END DIASTOLIC VOLUME 审中-公开
标题翻译：心脏末端胶质体积调节装置
公开(公告)号：WO2009018358A2
公开(公告)日：2009-02-05
申请号：PCT/US2008/071618
申请日：2008-07-30
申请人： THE TEXAS A & M UNIVERSITY SYSTEM , CRISCIONE, John, C. , BISWAS, Saurabh
发明人： CRISCIONE, John, C. , BISWAS, Saurabh
IPC分类号： A61B19/00 , A61F2/00
CPC分类号： A61M1/107 , A61M1/106 , A61M1/1068 , A61M1/12 , A61N1/3627
摘要： The present invention provides methods, systems, kits and devices that reduce dyskinesis and hypokinesis. For example, the direct compression cardiac device may be positioned about at least a portion of a heart, and includes a resilient inner panel in contact with at least a portion of the heart periphery, one or more resilient members positioned about the resilient inner panel and at least partially surrounded by an expandable outer panel. The resistance supplied by the inner panel to the heart may be modulated to control the end-diastolic heart volume and remodel the heart, the resistance supplied by the expandable outer panel to the heart may be modulated to control the end-systolic heart volume and remodel the heart or both.
摘要翻译：本发明提供减少运动障碍和运动不良的方法，系统，试剂盒和装置。例如，直接压迫心脏装置可以围绕心脏的至少一部分定位，并且包括与心脏周边的至少一部分接触的弹性内板，围绕弹性内板定位的一个或多个弹性构件，以及至少部分地由可扩张的外板包围。内部面板向心脏提供的电阻可以被调制以控制舒张末期的心脏体积并改造心脏，由可扩张的外部面板向心脏提供的电阻可以被调制以控制收缩期的心脏体积和改造心脏或两者。

3. 发明申请

WO2008124630A1 CONTAINER FOR KEEPING COMPONENT SEPARATE UP TO THEIR USE 审中-公开
标题翻译：用于保持组件的容器分离到其使用
公开(公告)号：WO2008124630A1
公开(公告)日：2008-10-16
申请号：PCT/US2008/059470
申请日：2008-04-04
申请人： INJEXXION, INC. , MCKENNA, Larry , RECORD, Chris
发明人： MCKENNA, Larry , RECORD, Chris
IPC分类号： B65D25/08
CPC分类号： B65D51/2835
摘要： The present invention includes dispensers, containers, methods of making and using dispensers with a fitting to attach to a second container and position a reservoir about the second container. The reservoir includes a diaphragm positioned opposite an orifice and a hollow perforator slidably positioned in the orifice. The hollow perforator includes a perforator portion and an access port portion that forms a chamber to hold one or more components. The one or more components may be released from the chamber without the removal of the dispenser from a container.
摘要翻译：本发明包括分配器，容器，制造和使用具有配件的分配器附接到第二容器并将储存器围绕第二容器定位的方法。储存器包括与孔相对设置的隔膜和可滑动地定位在孔口中的中空穿孔器。中空穿孔器包括穿孔部分和形成用于容纳一个或多个部件的室的进入口部分。一个或多个部件可以从腔室释放而不将分配器从容器中取出。

4. 发明申请

WO2008022332A2 SYSTEM, METHOD AND KIT FOR REPLICATING A DNA ARRAY 审中-公开
标题翻译：系统，方法和替代DNA阵列的工具箱
公开(公告)号：WO2008022332A2
公开(公告)日：2008-02-21
申请号：PCT/US2007/076244
申请日：2007-08-17
申请人： BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM , CROOKS, Richard, M. , JOOHOON, Kim , SUN, Li , LIN, Haohao
发明人： CROOKS, Richard, M. , JOOHOON, Kim , SUN, Li , LIN, Haohao
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6834 , C12Q1/6837 , C12Q2565/537 , C12Q2563/131 , C12Q2525/197
摘要： The present invention includes methods, systems and kits for replicating an oligonucleotide array. The replication includes hybridizing one or more biotin-functionalized oligonucleotides to one or more oligonucleotides on a first substrate and capturing the one or more biotin-functionalized oligonucleotides with streptavidin attached to a second substrate. The one or more biotin- functionalized oligonucleotides may be separated from the one or more oligonucleotides by mechanical force to form a replicated array.
摘要翻译：本发明包括用于复制寡核苷酸阵列的方法，系统和试剂盒。所述复制包括将一种或多种生物素官能化寡核苷酸与第一底物上的一种或多种寡核苷酸杂交，并用附着于第二底物的链霉抗生物素蛋白捕获所述一种或多种生物素官能化的寡核苷酸。一个或多个生物素官能化的寡核苷酸可以通过机械力从一个或多个寡核苷酸分离以形成复制阵列。

5. 发明申请

WO2007084103A2 HIGH TEMPERATURE ION CHANNELS AND PORES 审中-公开
标题翻译：高温离子通道和孔
公开(公告)号：WO2007084103A2
公开(公告)日：2007-07-26
申请号：PCT/US2005/046649
申请日：2005-12-21
申请人： THE TEXAS A & M UNIVERSITY SYSTEM , KANG, Xiaofeng , GU, Li Qun, Andrew , CHELEY, Stephen , BAYLEY, Hagan
发明人： KANG, Xiaofeng , GU, Li Qun, Andrew , CHELEY, Stephen , BAYLEY, Hagan
IPC分类号： G01N33/53
CPC分类号： G01N33/54366 , G01N33/48721 , G01N33/54393 , G01N33/6872
摘要： The present invention includes an apparatus, system and method for stochastic sensing of an analyte to a protein pore. The protein pore may be an engineer protein pore, such as an ion channel at temperatures above 55°C and even as high as near 100°C. The analyte may be any reactive analyte, including chemical weapons, environmental toxins and pharmaceuticals. The analyte covalently bonds to the sensor element to produce a detectable electrical current signal. Possible signals include change in electrical current. Detection of the signal allows identification of the analyte and determination of its concentration in a sample solution. Multiple analytes present in the same solution may also be detected.
摘要翻译：本发明包括用于将分析物随机感测到蛋白质孔的装置，系统和方法。蛋白质孔可以是工程蛋白孔，例如在55℃以上甚至高达100℃附近的离子通道。分析物可以是任何反应性分析物，包括化学武器，环境毒素和药物。分析物共价结合到传感器元件以产生可检测的电流信号。可能的信号包括电流变化。信号的检测允许识别分析物并确定其在样品溶液中的浓度。同一解决方案中存在的多种分析物也可能被检测到。

6. 发明申请

WO2007011639A3 CATALYTIC IMMUNOGLOBULINS 审中-公开
公开(公告)号：WO2007011639A3
公开(公告)日：2007-01-25
申请号：PCT/US2006/027185
申请日：2006-07-13
申请人： COIMMUNE INC. , HANSON, Carl, Veith , WEKSLER, Marc , PAUL, Sudhir , NISHIYAMA, Yasuhiro
发明人： HANSON, Carl, Veith , WEKSLER, Marc , PAUL, Sudhir , NISHIYAMA, Yasuhiro
IPC分类号： C07K16/00 , C12N9/00 , A61K39/395
摘要： The present invention describes the composition of class and subclass selected pooled human immunoglobulins with catalytic activity, methods of preparation thereof, and therapeutic utility thereof.

7. 发明申请

WO2006078861A2 METHOD, SYSTEM AND APPARATUS FOR A TIME STAMPED VISUAL MOTION SENSOR 审中-公开
标题翻译：用于时间标记的视觉运动传感器的方法，系统和设备
公开(公告)号：WO2006078861A2
公开(公告)日：2006-07-27
申请号：PCT/US2006/001970
申请日：2006-01-18
申请人： BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM , ZHANG, Guangbin , LIU, Jin
发明人： ZHANG, Guangbin , LIU, Jin
IPC分类号： G08B13/18 , C12Q1/68 , G06M7/00 , G08B21/00 , G06K9/00 , H04N7/18
CPC分类号： G06T7/246 , G06T2200/28
摘要： The present invention provides a method, system and apparatus for a time stamped visual motion sensor that provides a compact pixel size, higher speed motion detection and accuracy in velocity computation, high resolution, low power integration and reduces the data transfer and computation load of the following digital processor. The present invention provides a visual motion sensor cell that includes a photosensor, an edge detector connected to the photosensor and a time stamp component connected to the edge detector. The edge detector receives inputs from the photosensor and generates a pulse when a moving edge is detected. The time stamp component tracks a time signal and samples a time voltage when the moving edge is detected. The sampled time voltage can be stored until the sampled time voltage is read. In addition, the edge detector can be connected to one or more neighboring photosensors to improve sensitivity and robustness.
摘要翻译：本发明提供了一种用于时间标记的视觉运动传感器的方法，系统和设备，其提供了紧凑的像素尺寸，更高速度的运动检测和速度计算精度，高分辨率，低功率积分并减少以下数字处理器的数据传输和计算负载。本发明提供一种视觉运动传感器单元，其包括光电传感器，连接到光电传感器的边缘检测器和连接到边缘检测器的时间戳部件。边缘检测器接收来自光电传感器的输入，并在检测到移动边缘时产生脉冲。时间标记组件追踪时间信号并在检测到运动边缘时采样时间电压。采样时间电压可以被存储直到读取采样时间电压。此外，边缘检测器可以连接到一个或多个相邻的光电传感器，以提高灵敏度和鲁棒性。

8. 发明申请

WO2006053225A2 PROTEIN-NOBLE METAL NANOPARTICLES 审中-公开
标题翻译：蛋白质贵金属纳米粒子
公开(公告)号：WO2006053225A2
公开(公告)日：2006-05-18
申请号：PCT/US2005/040943
申请日：2005-11-11
申请人： BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM , YACAMAN, Miguel, Jose , ELECHIGUERRA, Jose, Luis , LARA, Humberto , BURT, Justin, Lockheart
发明人： YACAMAN, Miguel, Jose , ELECHIGUERRA, Jose, Luis , LARA, Humberto , BURT, Justin, Lockheart
IPC分类号： A61K33/38 , A61K9/14
CPC分类号： A61K38/02 , A61K33/24 , A61K33/38 , A61K47/52 , A61K47/6923 , A61K47/6929 , B82Y5/00 , A61K2300/00
摘要： The present invention is a composition and method of making protein-noble metal nanoparticles and methods for using the same as anti-virals.
摘要翻译：本发明是制备蛋白质 - 贵金属纳米颗粒的组合物和方法以及使用其作为抗病毒剂的方法。

9. 发明申请

WO2006050511A2 BUTYROPHENOMENES AND SIGMA-1 RECEPTOR ANTAGONISTS PROTECT AGAINST OXIDATIVES-STRESS 审中-公开
标题翻译：丁酰苯丙氨酸和SIGMA-1受体拮抗剂保护抗氧化剂 - 应激
公开(公告)号：WO2006050511A2
公开(公告)日：2006-05-11
申请号：PCT/US2005/040090
申请日：2005-11-03
申请人： UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH , SCHETZ, John, A. , SIMPKINS, James , ALBERT, Jeffery
发明人： SCHETZ, John, A. , SIMPKINS, James , ALBERT, Jeffery
IPC分类号： A61K31/445 , A61K31/137 , A61K31/12
CPC分类号： A61K31/12 , A61K31/137 , A61K31/445
摘要： The present invention includes compositions and methods for the protection of one or more central nervous system cells from trauma, when administered before, during or after the trauma, wherein the composition includes an effective amount of a butyrophenone, e.g., a 1-linked phenyl butyrophenone that is electronegative along the butyl chain and/or a Sigma-1 receptor antagonist.
摘要翻译：本发明包括当在创伤之前，之中或之后施用时保护一种或多种中枢神经系统细胞免受外伤的组合物和方法，其中所述组合物包含有效量的丁酰苯，例如，沿丁基链负电性的1'shy;连接的苯基丁酰苯和/或Sigma-1受体拮抗剂。

10. 发明申请

WO2006047515A2 DENDRITIC CELLS LOADED WITH HEAT SHOCKED MELANOMA CELL BODIES 审中-公开
标题翻译：树突状细胞装载热休克蛋白细胞体
公开(公告)号：WO2006047515A2
公开(公告)日：2006-05-04
申请号：PCT/US2005/038360
申请日：2005-10-25
申请人： BAYLOR RESEARCH INSTITUTE , PALUCKA, Anna, Karolina , BANCHEREAU, Jacques
发明人： PALUCKA, Anna, Karolina , BANCHEREAU, Jacques
IPC分类号： A61K39/00 , C12N5/08
CPC分类号： A61K35/28 , A61K39/0011 , A61K2039/5152 , A61K2039/5154 , A61K2039/5156 , A61K2039/6043
摘要： The present invention includes compositions and methods for the isolation, purification and preparation of immunogenic antigens for the production of customized cancer vaccines that include dendritic cells that are contacted with an antigen that includes heat-shocked cancer cells.
摘要翻译：本发明包括用于分离，纯化和制备用于产生定制的癌症疫苗的免疫原性抗原的组合物和方法，所述定制的癌症疫苗包括与包含热休克癌细胞的抗原接触的树突细胞。

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