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1. 发明申请

WO2020257017A1 INGESTIBLE DEVICE WITH COMPONENT CAPABLE OF RESIDING IN THE GASTROINTESTINAL TRACT 审中-公开
公开(公告)号：WO2020257017A1
公开(公告)日：2020-12-24
申请号：PCT/US2020/036920
申请日：2020-06-10
申请人： PROGENITY, INC.
发明人： JONES, Ryan Elliott , GOLUCH, Edgar D.
IPC分类号： A61B5/07 , A61B5/00 , A61K9/48 , A61B5/145
摘要： An ingestible device includes a capsule containing an SLS. The capsule degrades at a desired location in the GI tract, such as the intestine, thereby allowing the SLS to expand and engage the walls of the intestine. Upon such expansion/engagement, the SLS is sufficiently resistant to forces within the GI tract, such as peristaltic forces within the intestine, to allow the SLS to reside within the GI tract in a relatively stable manner and/or for a relatively long time. The SLS may include one or more functional components as described herein. Related components, systems and methods are disclosed.

2. 发明申请

WO2020191121A1 METHOD FOR IMAGING A REGION OF INTEREST OF A SAMPLE USING A TOMOGRAPHIC X-RAY MICROSCOPE, MICROSCOPE, SYSTEM AND COMPUTER PROGRAM 审中-公开
公开(公告)号：WO2020191121A1
公开(公告)日：2020-09-24
申请号：PCT/US2020/023494
申请日：2020-03-19
申请人： CARL ZEISS SMT INC.
发明人： CASE, Thomas Anthony , CANDELL, Susan , KOTWAL, Naomi , GU, Allen , LECHNER, Lorenz , BRODERICK, Wayne
IPC分类号： G21K7/00 , G06T7/73
摘要： A method for imaging a region of interest of a sample using a tomographic X-ray microscope, the method comprising the steps of: registering a position of the sample, the step of registering including: imaging a portion of the sample containing a feature using the microscope, identifying the feature by matching the feature to a pre-recorded feature, and determining a relative position of the feature in relation to the pre-recorded feature, navigating a field of view of the microscope over the region of interest based on the registered position of the sample, and imaging the region of interest using the microscope.

3. 发明申请

WO2018111466A1 INGESTIBLE DEVICE RECOVERY SYSTEM 审中-公开
公开(公告)号：WO2018111466A1
公开(公告)日：2018-06-21
申请号：PCT/US2017/061024
申请日：2017-11-10
申请人： JONES, Mitchell Lawrence , WAHL, Christopher Loren , LILLIS, Alec John
发明人： JONES, Mitchell Lawrence , WAHL, Christopher Loren , LILLIS, Alec John
IPC分类号： A61B1/04 , A61B10/00 , A61B5/07 , A61B10/04
摘要： Various embodiments are described herein for a recovery tool kit system including a recovery tool and an associated retrieval method for retrieving and storing an ingestible device.

4. 发明申请

WO2018048754A8 SYSTEMS AND METHODS FOR EXTRACTING A SAMPLE FROM AN INGESTIBLE DEVICE 审中-公开
标题翻译：用于从可消化装置中提取样品的系统和方法
公开(公告)号：WO2018048754A8
公开(公告)日：2018-03-15
申请号：PCT/US2017/049973
申请日：2017-09-01
申请人： JONES, Mitchell Lawrence , WAHL, Christopher Loren , PHILIPPSEN, Aaron Olafur Laurence , LEMAY, Matthieu Olivier , ALLAN, Nicholas David
发明人： JONES, Mitchell Lawrence , WAHL, Christopher Loren , PHILIPPSEN, Aaron Olafur Laurence , LEMAY, Matthieu Olivier , ALLAN, Nicholas David
IPC分类号： G01N1/28 , A61B5/00
摘要： Systems and methods for extracting and/or analyzing a sample, such as a sample present in an ingestible device, are disclosed. Methods for extracting a sample from an ingestible device via centrifugation, are also disclosed. Additionally, a sleeve device and adapter configured to extract the sample from the ingestible device and grating the device to remove a portion of the housing of said ingestible device, are disclosed.
摘要翻译：公开了用于提取和/或分析诸如存在于可摄取装置中的样本的样本的系统和方法。还公开了通过离心从可摄取装置提取样品的方法。另外，公开了一种套筒装置和适配器，其被构造成从可摄入装置提取样品并且使该装置光滑以移除所述可摄入装置的壳体的一部分。

5. 发明申请

WO2012008974A1 PUPIL DEPENDENT WAVEFRONT REFRACTION 审中-公开
标题翻译： PUPIL依赖性WAVEFRONT REFRACTION
公开(公告)号：WO2012008974A1
公开(公告)日：2012-01-19
申请号：PCT/US2010/050658
申请日：2010-09-29
申请人： CARL ZEISS VISION INC. , CARL ZEISS VISION GMBH , SPRATT, Ray Steven , KRATZER, Timo , CABEZA, Jesus Miguel Guillen
发明人： SPRATT, Ray Steven , KRATZER, Timo , CABEZA, Jesus Miguel Guillen
IPC分类号： A61B3/103 , G09B23/28
CPC分类号： A61B3/1015 , A61B3/0025
摘要： A method of determining an ophthalmic prescription (Rx) for a patient's eye, includes obtaining a wavefront measurement of the patient's eye; determining a first Rx for the patient's eye from the wavefront measurement, the first Rx corresponding to a maximum value of a merit function calculated from the wavefront measurement of the patient's eye for a first size of the pupil of the patient's eye; determining one or more additional Rx's of the patient's eye for one or more additional pupil sizes different from the first pupil size, wherein each additional Rx is determined for a corresponding size by calculating a value of the merit function for the previously-calculated Rx at the corresponding size and searching for an Rx at the corresponding size that provides a larger value of the merit function than the previously-calculated Rx at the corresponding size; determining a final Rx based on the first Rx and the additional Rx's; and outputting the final Rx.
摘要翻译：确定患者眼睛的眼科处方（Rx）的方法包括：获得患者眼睛的波前测量; 从波前测量确定患者眼睛的第一Rx，第一Rx对应于从患者眼睛的第一大小的患者眼睛的波前测量计算的优值函数的最大值; 确定与第一瞳孔大小不同的一个或多个附加瞳孔尺寸的患者眼睛的一个或多个附加的Rx，其中通过计算先前计算的Rx的优值函数的值来确定每个附加的Rx对应的大小以相应的大小搜索相对应的尺寸的Rx，其提供比先前计算的相应尺寸的Rx更好的优值函数值; 基于第一Rx和附加Rx确定最终的Rx; 并输出最终的Rx。

6. 发明申请

WO2010144267A1 METHOD AND SYSTEM FOR HEATING A TIP APEX OF A CHARGED PARTICLE SOURCE 审中-公开
标题翻译：用于加热充电颗粒源的提示APEX的方法和系统
公开(公告)号：WO2010144267A1
公开(公告)日：2010-12-16
申请号：PCT/US2010/036527
申请日：2010-05-28
申请人： CARL ZEISS NTS, LLC , NOTTE IV, John A. , PERCIVAL, Randy , RAHMAN, Milton , BARRISS, Louise , MELLO, Russ , DIMANNA, Mark D.
发明人： NOTTE IV, John A. , PERCIVAL, Randy , RAHMAN, Milton , BARRISS, Louise , MELLO, Russ , DIMANNA, Mark D.
IPC分类号： H01J1/15 , G05D23/27
CPC分类号： G05D23/27 , H01J37/08 , H01J37/22 , H01J37/242 , H01J37/243 , H01J2237/0807
摘要： System and method for heating an apex of a tip of a charged particle source, for example, a gas ion source, comprising a detector configured to detect light generated by the tip apex, and a controller coupled with the charged particle source and the detector so that the controller can control heating of the tip apex based on the light detected by the detector.
摘要翻译：用于加热带电粒子源的尖端的例如气体离子源的顶点的系统和方法，包括检测器，其被配置为检测由尖端尖端产生的光，以及与带电粒子源和检测器耦合的控制器控制器可以基于由检测器检测到的光来控制尖端顶点的加热。

7. 发明申请

WO2010005622A2 TELESCOPING DEVICES 审中-公开
标题翻译：望远镜装置
公开(公告)号：WO2010005622A2
公开(公告)日：2010-01-14
申请号：PCT/US2009/042668
申请日：2009-05-04
申请人： KONARKA TECHNOLOGIES, INC. , PALMER, Samuel
发明人： PALMER, Samuel
IPC分类号： H01L31/045
CPC分类号： H01L27/301 , H01G9/2068 , H01L51/0037 , H01L51/0097 , H01L51/4226 , H02S30/20 , Y02E10/549 , Y02P70/521
摘要： Telescoping devices, as well as related components, systems, and methods, are disclosed.
摘要翻译：公开了伸缩装置以及相关部件，系统和方法。

8. 发明申请

WO2009155272A2 CROSS-SECTION SYSTEMS AND METHODS 审中-公开
标题翻译：交叉系统和方法
公开(公告)号：WO2009155272A2
公开(公告)日：2009-12-23
申请号：PCT/US2009/047474
申请日：2009-06-16
申请人： CARL ZEISS SMT. INC. , SCIPIONI, Lawrence , KNIPPELMEYER, Rainer , RIEDESEL, Christoph , MORGAN, John , MANTZ, Ulrich , WAGEMANN, Ulrich
发明人： SCIPIONI, Lawrence , KNIPPELMEYER, Rainer , RIEDESEL, Christoph , MORGAN, John , MANTZ, Ulrich , WAGEMANN, Ulrich
IPC分类号： H01J37/30
CPC分类号： G01N1/286 , H01J2237/0807 , H01J2237/304 , H01J2237/31745 , H01L22/12 , H01L2924/0002 , H01L2924/00
摘要： Cross-section systems and methods are disclosed. Methods can include imaging a cross-section of a first sample, and simultaneously preparing a cross-section of a second sample so that the cross-section of the second sample can be imaged. The first and second samples can be, for example, first and second semiconductor articles, respectively.
摘要翻译：公开了截面系统和方法。方法可以包括对第一样品的横截面进行成像，并且同时制备第二样品的横截面，使得可以对第二样品的横截面进行成像。第一和第二样品可以分别为例如第一和第二半导体制品。

9. 发明申请

WO2009111149A1 GAS FIELD ION SOURCE WITH COATED TIP 审中-公开
标题翻译：气体离子源，带涂层
公开(公告)号：WO2009111149A1
公开(公告)日：2009-09-11
申请号：PCT/US2009/034000
申请日：2009-02-13
申请人： ALIS CORPORATION , NOTTE IV, John V.
发明人： NOTTE IV, John V.
IPC分类号： H01J37/08 , H01J27/26 , H01J37/065 , H01J37/26 , H01J37/30
CPC分类号： H01J49/168 , H01J27/26 , H01J37/065 , H01J37/08 , H01J37/28 , H01J2237/06341 , H01J2237/0807 , H01J2237/28
摘要： Coated tips, as well as related articles, systems and methods are disclosed.
摘要翻译：披露了涂层技巧，以及相关文章，系统和方法。

10. 发明申请

WO2008118808A1 LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY 审中-公开
标题翻译：液相色谱 - 质谱
公开(公告)号：WO2008118808A1
公开(公告)日：2008-10-02
申请号：PCT/US2008/057902
申请日：2008-03-21
申请人： ADVION BIOSCIENCE, INC. , SCHULTZ, Gary, A. , QUEIROS DE ALMEIDA, Reinaldo, Rodrigo , ALLEN, Mark, Hayden
发明人： SCHULTZ, Gary, A. , QUEIROS DE ALMEIDA, Reinaldo, Rodrigo , ALLEN, Mark, Hayden
IPC分类号： G01N30/80 , G01N30/72
CPC分类号： G01N30/80 , G01N30/6095 , G01N30/7266 , G01N2030/8447
摘要： A liquid chromatography/mass spectrometry system includes a chromatographic column (12) through which an effluent passes, wherein the effluent comprises a plurality of analytes that correspond to a plurality of chromatographic peaks and an eluent; a post-column splitter (14) having at least two output ports through which the effluent of the column is split to at least a first portion and a second portion; a mass spectrometer configured to receive the first portion from a first of the output ports for analysis; and a tube (10) connected to a second of the output ports configured to prevent substantial evaporation of the eluent in the second portion until undergoing mass spectrometry. The second portion has a plurality of separated analytes corresponding to at least two chromatographic peaks. A method of using the system is also disclosed.
摘要翻译：液相色谱/质谱系统包括色谱柱（12），流出物通过该色谱柱（12），其中流出物包括对应于多个色谱峰和洗脱液的多个分析物; 柱分离器（14）具有至少两个输出端口，所述塔的流出物通过所述至少两个输出端口分裂成至少第一部分和第二部分; 质谱仪被配置为从第一输出端口接收第一部分用于分析; 以及连接到输出端口中的第二个输出端口的管（10），其被配置为防止第二部分中的洗脱液基本上蒸发，直到进行质谱分析。第二部分具有对应于至少两个色谱峰的多个分离的分析物。还公开了一种使用该系统的方法。

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