专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2011140359A3 SYSTEMS AND METHODS FOR DELIVERING A THERAPEUTIC AGENT 审中-公开
公开(公告)号：WO2011140359A3
公开(公告)日：2011-11-10
申请号：PCT/US2011/035384
申请日：2011-05-05
申请人： SPRINGLEAF THERAPEUTICS, INC. , BOOMA, Glenn, R. , PIZZOCHERO, Alessandro , GYORY, Richard, J.
发明人： BOOMA, Glenn, R. , PIZZOCHERO, Alessandro , GYORY, Richard, J.
IPC分类号： A61M5/148
摘要： Apparatus for delivering a therapeutic agent to a patient comprising a reservoir for containing a fluid, a first actuator, a transfer structure, and a second actuator. The first actuator exerting force upon the transfer structure, which in turn applies force upon the reservoir to expel fluid from the reservoir. The second actuator exerting a second force on the reservoir to expel fluid from the reservoir.

2. 发明申请

WO2011140475A2 SYSTEMS AND METHODS FOR DELIVERING A THERAPEUTIC AGENT 审中-公开
标题翻译：用于递送治疗剂的系统和方法
公开(公告)号：WO2011140475A2
公开(公告)日：2011-11-10
申请号：PCT/US2011/035573
申请日：2011-05-06
申请人： SPRINGLEAF THERAPEUTICS, INC. , CHIN, Timothy E. , GYORY, J. Richard , HAMILTON, Daniel , PIZZOCHERO, Alessandro , TAYLOR, Jon
发明人： CHIN, Timothy E. , GYORY, J. Richard , HAMILTON, Daniel , PIZZOCHERO, Alessandro , TAYLOR, Jon
IPC分类号： A61M5/142
CPC分类号： A61M5/14586 , A61M5/14248 , A61M5/145 , A61M2005/14252 , A61M2005/14506 , A61M2005/14513
摘要： Devices and methods for delivering a fluid to a patient are disclosed herein. In one embodiment, a delivery system includes a reservoir for containing a fluid and a fluid communicator in fluid communication with the reservoir. An electrochemical actuator is coupled to the reservoir and configured to exert a force on the reservoir upon actuation such that fluid within the reservoir is communicated through the fluid communicator. The actuator includes a first end that is constrained and a second end that is not constrained. The actuator is configured to bend at a location along a length of the actuator when actuated such that the second end of the actuator is displaced in a direction toward the fluid reservoir. The actuator can be an electrochemical actuator. The apparatus can further include a transfer structure disposed between the actuator and the reservoir configured to contact the reservoir upon actuation of the actuator.
摘要翻译：本文公开了用于将流体输送给患者的装置和方法。在一个实施例中，输送系统包括用于容纳流体的储存器和与储存器流体连通的流体通信器。电化学致动器联接到储存器并且构造成在致动时在储存器上施加力，使得储存器内的流体通过流体通信器传递。致动器包括被约束的第一端和不受约束的第二端。致动器构造成在致动器的沿着致动器的长度的位置处弯曲，使得致动器的第二端在朝向流体储存器的方向上移位。致动器可以是电化学致动器。该设备还可以包括设置在致动器和储存器之间的传送结构，该传送结构构造成在致动器致动时接触储存器。

3. 发明申请

WO2011140475A3 SYSTEMS FOR DELIVERING A THERAPEUTIC AGENT 审中-公开
标题翻译：用于递送治疗剂的系统
公开(公告)号：WO2011140475A3
公开(公告)日：2012-04-12
申请号：PCT/US2011035573
申请日：2011-05-06
申请人： SPRINGLEAF THERAPEUTICS INC , CHIN TIMOTHY E , GYORY J RICHARD , HAMILTON DANIEL , PIZZOCHERO ALESSANDRO , TAYLOR JON
发明人： CHIN TIMOTHY E , GYORY J RICHARD , HAMILTON DANIEL , PIZZOCHERO ALESSANDRO , TAYLOR JON
IPC分类号： A61M5/142
CPC分类号： A61M5/14586 , A61M5/14248 , A61M5/145 , A61M2005/14252 , A61M2005/14506 , A61M2005/14513
摘要： Devices and methods for delivering a fluid to a patient are disclosed herein. In one embodiment, a delivery system includes a reservoir for containing a fluid and a fluid communicator in fluid communication with the reservoir. An electrochemical actuator is coupled to the reservoir and configured to exert a force on the reservoir upon actuation such that fluid within the reservoir is communicated through the fluid communicator. The actuator includes a first end that is constrained and a second end that is not constrained. The actuator is configured to bend at a location along a length of the actuator when actuated such that the second end of the actuator is displaced in a direction toward the fluid reservoir. The actuator can be an electrochemical actuator. The apparatus can further include a transfer structure disposed between the actuator and the reservoir configured to contact the reservoir upon actuation of the actuator.
摘要翻译：本文公开了用于将流体输送给患者的装置和方法。在一个实施例中，输送系统包括用于容纳流体的储存器和与储存器流体连通的流体通信器。电化学致动器联接到储存器并且构造成在致动时在储存器上施加力，使得储存器内的流体通过流体通信器传递。致动器包括被约束的第一端和不受约束的第二端。致动器构造成在致动器的沿着致动器的长度的位置处弯曲，使得致动器的第二端在朝向流体储存器的方向上移位。致动器可以是电化学致动器。该设备还可以包括设置在致动器和储存器之间的传送结构，该传送结构构造成在致动器致动时接触储存器。

4. 发明申请

WO2011140445A1 SYSTEMS AND METHODS FOR DELIVERING A THERAPEUTIC AGENT USING MECHANICAL ADVANTAGE 审中-公开
标题翻译：使用机械优势递送治疗药物的系统和方法
公开(公告)号：WO2011140445A1
公开(公告)日：2011-11-10
申请号：PCT/US2011/035527
申请日：2011-05-06
申请人： SPRINGLEAF THERAPEUTICS, INC. , GYORY, J. Richard , PIZZOCHERO, Alessandro
发明人： GYORY, J. Richard , PIZZOCHERO, Alessandro
IPC分类号： A61M5/20
CPC分类号： A61M5/16877 , A61M5/14248 , A61M5/145 , A61M5/14526 , A61M5/14593 , A61M31/00 , A61M35/00 , A61M2005/14252 , A61M2005/14513
摘要： Devices and methods for delivering a therapeutic agent to a patient are disclosed herein. In one embodiment, a delivery system includes a reservoir containing a fluid and a fluid communicator in fluid communication with the reservoir. An actuator is coupled to the reservoir and configured to displace and exert a force on the reservoir for a time period upon actuation such that fluid within the reservoir is communicated through the fluid communicator. An amplification mechanism is coupled to the actuator. The amplification mechanism is configured to increase at least one of the force, the displacement, or the time period the force is exerted by the actuator on the reservoir. In some embodiments, a transfer structure is disposed between the amplification mechanism and the reservoir. The transfer structure is configured to contact the reservoir upon actuation of the actuator. In some embodiments, the actuator can be an electrochemical actuator.
摘要翻译：本文公开了将治疗剂递送至患者的装置和方法。在一个实施例中，输送系统包括容纳流体的储存器和与储存器流体连通的流体通信器。致动器联接到储存器并且构造成在致动时在储存器上移动并施加力一段时间，使得储存器内的流体通过流体通信器传递。放大机构联接到致动器。放大机构被配置为增加力，位移或者由致动器施加在储存器上的力的时间段中的至少一个。在一些实施例中，转移结构设置在放大机构和储存器之间。转移结构构造成在致动器的致动时接触储存器。在一些实施例中，致动器可以是电化学致动器。

5. 发明申请

WO2011140359A2 SYSTEMS AND METHODS FOR DELIVERING A THERAPEUTIC AGENT 审中-公开
标题翻译：用于递送治疗剂的系统和方法
公开(公告)号：WO2011140359A2
公开(公告)日：2011-11-10
申请号：PCT/US2011035384
申请日：2011-05-05
申请人： SPRINGLEAF THERAPEUTICS INC , BOOMA GLENN R , PIZZOCHERO ALESSANDRO , GYORY RICHARD J
发明人： BOOMA GLENN R , PIZZOCHERO ALESSANDRO , GYORY RICHARD J
IPC分类号： A61M37/00
CPC分类号： A61M5/145 , A61M5/14248 , A61M31/00 , A61M35/00 , A61M37/00 , A61M2005/14506 , A61M2005/14513
摘要： Devices, methods, and kits for delivering a therapeutic agent to a patient are disclosed herein. In one embodiment, an apparatus comprises a reservoir for containing a fluid, a first actuator, a transfer structure, and a second actuator. The first actuator has a first configuration and a second configuration and is configured to exert a first force on the reservoir when moved from its first configuration to its second configuration such that a first volume of fluid within the reservoir is communicated out of the fluid reservoir. The transfer structure is disposed between the first actuator and the reservoir and has a surface configured to engage the reservoir such that the first force exerted by the first actuator is distributed across a surface of the reservoir engaged by the transfer structure. The second actuator has a first configuration and a second configuration and is configured to exert a second force on the reservoir when the second actuator is moved from its first configuration to its second configuration such that a second volume of fluid within the reservoir is communication out of the fluid reservoir.
摘要翻译：本文公开了用于将治疗剂递送至患者的装置，方法和试剂盒。在一个实施例中，装置包括用于容纳流体的储存器，第一致动器，转印结构和第二致动器。第一致动器具有第一构造和第二构造，并且构造成当从其第一构型移动到其第二构造时在储存器上施加第一力，使得储存器内的第一体积的流体被连通到流体储存器外。转移结构设置在第一致动器和储存器之间，并且具有构造成与储存器接合的表面，使得由第一致动器施加的第一力分布在由传送结构接合的储存器的表面上。第二致动器具有第一构造和第二构造，并且构造成当第二致动器从其第一构型移动到其第二构造时在储存器上施加第二力，使得储存器内的第二体积的流体从流体储存器。

6. 发明申请

WO2011140356A1 SYSTEMS AND METHODS FOR DELIVERING A THERAPEUTIC AGENT USING MECHANICAL ADVANTAGE 审中-公开
标题翻译：使用机械优势递送治疗剂的系统和方法
公开(公告)号：WO2011140356A1
公开(公告)日：2011-11-10
申请号：PCT/US2011/035381
申请日：2011-05-05
申请人： SPRINGLEAF THERAPEUTICS, INC. , GYORY, J., Richard , PIZZOCHERO, Alessandro
发明人： GYORY, J., Richard , PIZZOCHERO, Alessandro
IPC分类号： A61M5/145 , A61M5/148
CPC分类号： A61M5/142 , A61M5/14244 , A61M5/14248 , A61M5/14586 , A61M5/148 , A61M2005/14506 , A61M2205/0272 , A61M2205/8206
摘要： Devices and methods for delivering a therapeutic agent to a patient are disclosed herein. In one embodiment, a delivery system includes a reservoir configured to contain a fluid, a first actuator coupled to the reservoir, a second actuator coupled to the first actuator, and an adaptor at least partially disposed between the first actuator and the second actuator. The first actuator and the second actuator are configured to collectively exert a force on the reservoir such that at least a portion of the fluid within the reservoir is communicated out of the reservoir. The adaptor is configured to couple the first actuator and the second actuator.
摘要翻译：本文公开了将治疗剂递送至患者的装置和方法。在一个实施例中，输送系统包括被配置为容纳流体的储存器，耦合到储存器的第一致动器，联接到第一致动器的第二致动器以及至少部分地设置在第一致动器和第二致动器之间的适配器。第一致动器和第二致动器构造成共同地在储存器上施加力，使得储存器内的流体的至少一部分被连通出储存器。适配器被配置为联接第一致动器和第二致动器。

7. 发明公开

EP2652324A2 ELECTROCHEMICAL ACTUATORS 审中-公开
标题翻译：电化学执行器
公开(公告)号：EP2652324A2
公开(公告)日：2013-10-23
申请号：EP11811450.3
申请日：2011-12-16
申请人： Massachusetts Institute Of Technology , Springleaf Therapeutics Inc.
发明人： CHIANG, Yet-Ming , CHIN, Timothy, E. , CIMA, Michael J. , GYORY, J., Richard
IPC分类号： F03G7/00 , H01M4/02
CPC分类号： H01M14/00 , F03G7/005 , H01M4/131 , H01M4/134 , H01M10/052 , H01M10/058
摘要： Devices and methods for providing electrochemical actuation are described herein. In one embodiment, an actuator device includes an electrochemical cell including a negative electrode and a positive electrode At least a portion of the negative electrode is formed with a material formulated to at least one of intercalate, de-intercalate, alloy with, oxidize, reduce, or plate with a first portion of the positive electrode to an extent different than with a second portion of the positive electrode such that a differential strain is imparted between the first portion and the second portion of the positive electrode and such that at least a portion of the electrochemical cell is displaced. The electrochemical cell includes a portion that is pre-bent along an axis of the electrochemical cell to define a fold axis and the displacement of the at least a portion of the electrochemical cell is maximized along the fold axis.

8. 发明公开

EP2571551A2 SYSTEMS AND METHODS FOR DELIVERING A THERAPEUTIC AGENT 审中-公开
标题翻译：系统和方法的治疗剂的释放
公开(公告)号：EP2571551A2
公开(公告)日：2013-03-27
申请号：EP11727829.1
申请日：2011-05-06
申请人： Springleaf Therapeutics Inc.
发明人： CHIN, Timothy E. , GYORY, J. Richard , HAMILTON, Daniel , PIZZOCHERO, Alessandro , TAYLOR, Jon
IPC分类号： A61M5/142
CPC分类号： A61M5/14586 , A61M5/14248 , A61M5/145 , A61M2005/14252 , A61M2005/14506 , A61M2005/14513
摘要： Devices and methods for delivering a fluid to a patient are disclosed herein. In one embodiment, a delivery system includes a reservoir for containing a fluid and a fluid communicator in fluid communication with the reservoir. An electrochemical actuator is coupled to the reservoir and configured to exert a force on the reservoir upon actuation such that fluid within the reservoir is communicated through the fluid communicator. The actuator includes a first end that is constrained and a second end that is not constrained. The actuator is configured to bend at a location along a length of the actuator when actuated such that the second end of the actuator is displaced in a direction toward the fluid reservoir. The actuator can be an electrochemical actuator. The apparatus can further include a transfer structure disposed between the actuator and the reservoir configured to contact the reservoir upon actuation of the actuator.

9. 发明申请

US20140350528A1 SYSTEMS AND METHODS FOR DELIVERING A THERAPEUTIC AGENT 审中-公开
标题翻译：用于递送治疗剂的系统和方法
公开(公告)号：US20140350528A1
公开(公告)日：2014-11-27
申请号：US14215485
申请日：2014-03-17
申请人： SpringLeaf Therapeutics, Inc.
发明人： Yet-Ming CHIANG , Timothy E. CHIN , Michael J. CIMA , J. Richard GYORY , Malinda TUPPER
IPC分类号： A61M5/142
CPC分类号： A61M5/14248 , A61M5/148
摘要： Devices and methods for delivering a fluid to a patient are disclosed herein. In one embodiment, a method includes providing a wearable delivery device that includes an electrochemical actuator and a reservoir containing a fluid with viscosity greater than 15 cP. The electrochemical actuator can be actuated such that the actuator exerts sufficient force on the reservoir to cause the fluid within the reservoir to be communicated to the patient's body over a time period. In some embodiments, the time period is two hours. In one embodiment, a delivery system includes a reservoir containing a fluid having a viscosity greater than 15 cP and a fluid communicator in fluid communication with the reservoir. An electrochemical actuator is coupled to the reservoir and configured to exert a sufficient force on the reservoir for a time period upon actuation such that the fluid within the reservoir is communicated through the fluid communicator.
摘要翻译：本文公开了用于将流体输送给患者的装置和方法。在一个实施方案中，一种方法包括提供包含电化学致动器和含有粘度大于15cP的流体的容器的耐磨输送装置。可以致动电化学致动器，使得致动器在储存器上施加足够的力使得储存器内的流体在一段时间内与患者的身体连通。在一些实施例中，时间段为两小时。在一个实施方案中，递送系统包括含有粘度大于15cP的流体的储存器和与储存器流体连通的流体通信器。电化学致动器耦合到储存器并且构造成在致动时在储存器上施加足够的力一段时间，使得储存器内的流体通过流体通信器传递。

10. 发明申请

US20140135699A1 SYSTEMS AND METHODS FOR DELIVERING A THERAPEUTIC AGENT 审中-公开
标题翻译：用于递送治疗剂的系统和方法
公开(公告)号：US20140135699A1
公开(公告)日：2014-05-15
申请号：US13673464
申请日：2012-11-09
申请人： J. Richard Gyory
发明人： J. Richard Gyory
IPC分类号： A61M5/145
CPC分类号： A61M5/148 , A61M5/1483
摘要： A delivery system includes a reservoir configured to contain a fluid and a fluid communicator configured to be placed in fluid communication with the reservoir. A first actuator is coupled to the reservoir and configured to exert a first force on the reservoir upon actuation. A transfer structure disposed between the first actuator and the reservoir is configured to engage the reservoir distribute the first force across a surface of the reservoir. A second actuator is disposed and oriented so that when the first actuator is displaced toward the fluid reservoir, the second actuator moves from a first configuration to a second configuration and exerts a second force on the transfer structure. The combination of the first and second forces collectively urge the transfer structure towards the reservoir such that fluid within the reservoir is communicated through the fluid communicator.
摘要翻译：输送系统包括构造成容纳流体的储存器和构造成与储存器流体连通的流体通信器。第一致动器联接到储存器并且构造成在致动时在储存器上施加第一力。设置在第一致动器和储存器之间的传送结构被配置成接合储存器将第一力分布在储存器的表面上。第二致动器被设置和定向成使得当第一致动器朝向流体储存器移位时，第二致动器从第一构造移动到第二构造并且在转移结构上施加第二力。第一和第二力的组合共同地将转移结构推向储存器，使得储存器内的流体通过流体通信器传递。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式