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    • 86. 发明公开
    • PYRIDAZINE DERIVATIVES
    • 哒嗪衍生物
    • EP2077997A1
    • 2009-07-15
    • EP07819250.7
    • 2007-10-23
    • Syngenta Participations AG
    • TRAH, StephanLAMBERTH, ClemensWENDEBORN, Sebastian
    • C07D237/08C07D237/12C07D237/14C07D237/18C07D237/04C07D405/04C07D409/04C07D401/04C07D403/04C07D413/04C07D417/04C07D401/12C07D409/12C07D307/60
    • C07D237/14A01N43/58C07D237/08C07D237/12C07D307/60C07D307/79C07D401/04C07D401/12C07D403/04C07D405/04C07D405/12C07D407/04C07D409/04C07D409/12C07D413/04C07D417/04
    • The present invention relates to novel pyridazine derivatives of formula (I) as active ingredients which have microbiocidal activity, in particular fungicidal activity: wherein R1 is hydrogen, C1-C6alkyl, C1-C8haloalkyl or C3-C6cycloalkyl; R2 is cycloalkyl, cycloalkylalkyl, halocycloalkyl, cycloalkoxy, halocycloalkoxy, cycloalkylalkoxy, halocycloalkylalkoxy, alkoxyalkyl, cycloalkoxyalkoxyalkyl, haloalkoxyalkyl, trialkylsilyl, alkylthioalkyl, haloalkylthioalkyl, cycloalkylthio, halocycloalkylthio, cycloalkylalkylthio, halocycloalkylalkylthio, alkylsulfinylalkyl, alkylsulfonylalkyl, alkylsulfinyl, haloalkylsulfinyl, alkylsulfonyl, haloalkylsulfonyl, C2-C6alkenyl, C2-C6alkynyl, optionally substituted arylsulfonyl, optionally substituted aryloxy, optionally substituted heteroaryloxy, optionally substituted arylthio, optionally substituted heteroarylthio; or R2 together with an adjacent carbon atom forms an optionally substituted fused ring; R3 is an optionally substituted aryl; R4 is hydrogen, halogen, C1-C6alkyl, C1-C6haloalkyl, C1-C8alkoxy, C1-C6haloalkoxy, hydroxy or cyano; and n is a whole number from 1 to 4; or an agrochemically usable salt form thereof.
    • 本发明涉及式(I),其具有杀微生物活性作为活性成分,特别是杀真菌活性的新颖的哒嗪衍生物:其中R1是氢,C1-C6烷基,C1-C8卤代烷基或C 3 -C 6环烷基; R 2是环烷基,环烷基烷基,卤代环烷基,环烷氧基,卤代环烷氧基,环烷基烷氧基,halocycloalkylalkoxy,烷氧基烷基,cycloalkoxyalkoxyalkyl,卤代烷氧基烷基,三烷基甲硅烷,烷硫基烷基,haloalkylthioalkyl,环烷硫基,halocycloalkylthio,cycloalkylalkylthio,halocycloalkylalkylthio,alkylsulfinylalkyl,烷基磺酰基烷基,烷基亚磺酰基,卤代烷,烷基磺酰基,卤代烷基磺酰基,C2- 任选取代的芳基磺酰基,任选取代的芳基氧基,任选取代的杂芳基氧基,任选取代的芳基硫基,任选取代的杂芳基硫基; 或R2与相邻碳原子一起形成任选取代的稠合环; R3是任选取代的芳基; R 4是氢,卤素,C 1 -C 6烷基,C 1 -C 6卤代烷基,C 1 -C 8烷氧基,C 1 -C 6卤代烷氧基,羟基或氰基; n是从1到4的整数; 或其农业化学可用的盐形式。
    • 89. 发明公开
    • PESTICIDALLY ACTIVE TETRAZINE DERIVATIVES
    • 农药有效四嗪
    • EP1187818A1
    • 2002-03-20
    • EP00938800.0
    • 2000-06-19
    • Syngenta Participations AG
    • ZAMBACH, WernerNAEF, RudolfTRAH, StephanJEANGUENAT, AndréEBERLE, MartinSTEIGER, Arthur
    • C07D257/08C07D401/04A01N43/713
    • C07D401/04A01N43/713C07D257/08
    • The invention relates to compounds of general formula (I), wherein T-V is -N=N- or -NH-NH-; X1 is R1; X2 and X3 are each independently of the other H or R1; R1 is for instance halogen, CN, NO2, C1-C6alkyl, C3-C8cycloalkyl, C1-C6haloalkyl, C3-C8halocycloalkyl, C1-C6alkoxy, C3-C8cycloalkoxy or C1-C6haloalkoxy; Ar1 is unsubstituted or mono- to tetra-substituted aryl or heteroaryl; Ar2 is unsubstituted or mono- to penta-substituted aryl or heteroaryl; A is a single bond, C1-C12alkylene, O, O(C1-C12alkylene), S(O)n, S(O)n(C1-C12alkylene), C2-C8alkenylene, C2-C8alkynylene; NR6, NR6(C1-C12alkylene) or C(=Z); Z is O, NR4, NNR4R5 or NOR4; R2 is H, C1-C6alkyl or C3-C8cycloalkyl; R4 and R5 are each independently of the other H, C1-C6alkyl or C1-C6haloalkyl; R6 is H, C1-C6alkyl, C3-C8cycloalkyl, C1-C6haloalkyl, C2-C8alkenyl, C2-C8alkynyl, aryl-C1-C6alkyl, (CH2)pC(O)R7 or C1-C6alkoxy-C2-C6alkyl; R7 is H, C1-C6alkyl, C3-C8cycloalkyl, C1-C6haloalkyl, C1-C6alkoxy, N(R8)2 or C1-C6alkoxy-C2-C6alkyl; R8 is H, C1-C6alkyl, C3-C8cycloalkyl, C1-C6haloalkyl or aryl-C1-C6alkyl; n is 0, 1 or 2; p is 0, 1, 2, 3, 4, 5, or 6; and Q is O or S; a process for the preparation of those compounds and their use; pesticides, the active ingredient of which is selected from those compounds; and a method of preparing those compositions and their use; intermediates in the preparation of those compounds; and a process for the preparation of those intermediates and their use.
    • 90. 发明公开
    • PESTICIDAL TRIAZINE DERIVATIVES
    • 署理农药三嗪衍生物
    • EP1175410A1
    • 2002-01-30
    • EP00922671.3
    • 2000-05-02
    • Syngenta Participations AG
    • STEIGER, ArthurZAMBACH, WernerJEANGUENAT, AndréEBERLE, MartinTRAH, StephanFAROOQ, Saleem
    • C07D253/06A01N43/707
    • A01N57/22A01N43/707C07D253/07
    • A compound of formula (I), wherein R1 is unsubstituted or substituted aryl or heteroaryl, the substituents of the aryl and heteroaryl rings being selected, for example, from the group consisting of OH, halogen, CN, NO2, C1-C6alkyl, C3-C8cycloalkyl, C1-C6alkyl-C3-C8cycloalkyl, C3-C8cycloalkyl-C1-C6alkyl, C1-C6haloalkyl, C3-C8halocycloalkyl, C1-C6alkoxy and phenyl; phenoxy; phenylthio; phenylamino; and phenyl-(C1-C6alkyl)-amino; the substituents of the phenoxy, phenylthio, phenylamino and phenyl-(C1-C6alkyl)-amino groups being selected from the group consisting of halogen, CN, NO2, C1-C6alkyl, C3-C8cycloalkyl, C1-C6haloalkyl, C3-C8halocycloalkyl, C1-C6alkoxy, C3-C8cycloalkoxy, C1-C6alkylthio, C3-C8cycloalkylthio, C1-C6haloalkylthio and C3-C8halocycloalkylthio; R2 is, for example, H, OH, halogen, CN, NO2, C1-C6alkyl or C1-C6alkoxy; A is, for example, a single bond, C1-C12alkylene, O or O(C1-C12alkylene); R4 is H, C1-C6alkyl, C3-C8cycloalkyl, C1-C6haloalkyl, C1-C6alkoxy, N(R5)2 or C1-C6alkoxy-C2-C6alkyl; R5 is H, C1-C6alkyl, C3-C8cycloalkyl, C1-C6haloalkyl or aryl-C1-C6alkyl; X1 is R10; X2 and X3 are each independently of the other H or R10; R10 is, for example, halogen, CN, NO2, C1-C6alkyl or C3-C8cycloalkyl; and n is 0, 1 or 2, and to their physiologically tolerable and agrochemically acceptable addition compounds, and where appropriate to E/Z isomers, to mixtures of E/Z isomers and/or to tautomers, in each case in free form or in salt form. The compounds, in free form or in agrochemically acceptable salt form, exhibit advantageous pesticidal properties. They are suitable especially in the control of pests in agriculture and stored goods and also in the keeping of domestic animals.