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81. 发明授权

US08409492B2 Method for producing aluminum titanate ceramic 有权
标题翻译：钛酸铝陶瓷的制造方法
公开(公告)号：US08409492B2
公开(公告)日：2013-04-02
申请号：US12707726
申请日：2010-02-18
申请人： Yasushi Noguchi , Atsushi Kaneda , Takayuki Inoue , Mariko Kusabe
发明人： Yasushi Noguchi , Atsushi Kaneda , Takayuki Inoue , Mariko Kusabe
IPC分类号： B28B3/20
CPC分类号： C04B35/478 , C04B38/0006 , C04B2111/00793 , C04B2111/0081 , C04B2235/3201 , C04B2235/3206 , C04B2235/3208 , C04B2235/3213 , C04B2235/3217 , C04B2235/3227 , C04B2235/3232 , C04B2235/3272 , C04B2235/3418 , C04B2235/528 , C04B2235/5436 , C04B2235/77 , F01N2330/06 , C04B38/0054 , C04B38/0074 , C04B38/0645
摘要： A method for producing an aluminum titanate ceramic, which comprises subjecting, to forming, a raw material for aluminum titanate formation, containing Na2O-containing α-alumina particles, to obtain a formed body and then firing the body, wherein the α-alumina particles has such a crystal structure that the ratio of the average value of the average length in axis a direction and the average length in axis b direction, to the average length H in axis c direction is 3 or more.
摘要翻译：一种钛酸铝陶瓷的制造方法，其特征在于，将含有含有Na 2 O的α-氧化铝粒子的钛酸铝形成用原料进行成型，得到成形体，然后烧结所述本体，其中，所述α-氧化铝粒子具有这样的晶体结构，使得轴方向的平均长度的平均值与轴b方向的平均长度与轴c方向的平均长度H的比例为3以上。

82. 发明申请

US20120034250A1 CONDENSED PYRROLOPYRIDINE DERIVATIVE 审中-公开
标题翻译：浓缩吡咯啉衍生物
公开(公告)号：US20120034250A1
公开(公告)日：2012-02-09
申请号：US13264008
申请日：2010-04-13
申请人： Shohei Shirakami , Yutaka Nakajima , Jun Maeda , Hiroaki Tominaga , Hiroaki Yamagishi , Takeshi Hondo , Masamichi Inami , Hiroki Morio , Takayuki Inoue , Tsuyoshi Mizutani , Hiroki Ishioka
发明人： Shohei Shirakami , Yutaka Nakajima , Jun Maeda , Hiroaki Tominaga , Hiroaki Yamagishi , Takeshi Hondo , Masamichi Inami , Hiroki Morio , Takayuki Inoue , Tsuyoshi Mizutani , Hiroki Ishioka
IPC分类号： A61K31/437 , A61K31/55 , A61P37/06 , A61K31/541 , A61K31/5377 , A61K31/496 , C07D471/14 , A61K31/497
CPC分类号： C07D471/14 , C07D519/00
摘要： [Problem]The present invention provides a condensed pyrrolopyridine derivative which is useful as an active ingredient for a pharmaceutical composition, in particular, a pharmaceutical composition for preventing or treating diseases caused by undesirable cytokine signal transduction or diseases caused by abnormal cytokine signal transduction.[Means for Solution]The present inventors have extensively studied a compound having a JAK inhibitory action, and as a result, they have found that a condensed pyrrolopyridine derivative which is the compound of the present invention has an excellent JAK inhibitory action, and is therefore useful as an agent for preventing or treating diseases caused by undesirable cytokine signal transduction or diseases caused by abnormal cytokine signal transduction, thereby completing the present invention.
摘要翻译：本发明提供可用作药物组合物的活性成分的特别是用于预防或治疗由不良细胞因子信号转导引起的疾病或由异常细胞因子信号转导引起的疾病的药物组合物的缩合吡咯并吡啶衍生物。 [解决方案]本发明人广泛研究了具有JAK抑制作用的化合物，结果发现，作为本发明化合物的缩合吡咯并吡啶衍生物具有优异的JAK抑制作用，因此可用作预防或治疗由不良细胞因子信号转导引起的疾病或由异常细胞因子信号转导引起的疾病的药剂，从而完成本发明。

83. 发明授权

US07978898B2 Image acquiring apparatus, image acquiring method, and image acquiring program 有权
标题翻译：图像获取装置，图像获取方法和图像获取程序
公开(公告)号：US07978898B2
公开(公告)日：2011-07-12
申请号：US12857110
申请日：2010-08-16
申请人： Shigeru Uchiyama , Takayuki Inoue , Masatoshi Okugawa , Jeremy Cooke
发明人： Shigeru Uchiyama , Takayuki Inoue , Masatoshi Okugawa , Jeremy Cooke
IPC分类号： G06K9/00
CPC分类号： G02B21/367
摘要： In acquisition of a micro image of a sample by a micro image acquiring unit, when a plurality of image acquiring ranges are set for the sample as an object of image acquisition, a plurality of corresponding focus information are set, and furthermore, when a plurality of partial images acquired by scanning the sample by the micro image acquiring unit include a partial image including mixing of a plurality of image acquiring ranges, the focus information is switched in the middle of scanning of the partial image. With such a structure, even when a plurality of objects are contained in the sample, images of the respective objects can be preferably acquired. Thereby, an image acquiring apparatus, an image acquiring method, and an image acquiring program which are capable of preferably acquiring images of a plurality of objects are realized even when the plurality of objects are contained in a sample.
摘要翻译：在通过微图像获取单元获取样本的微图像时，当为样本设置多个图像采集范围作为图像获取对象时，设置多个对应的焦点信息，此外，当多个通过由微图像获取单元扫描样本而获取的部分图像包括包括多个图像获取范围的混合的部分图像，在部分图像的扫描中间切换焦点信息。利用这种结构，即使在样本中包含多个对象，也可以优选地获取各个对象的图像。因此，即使当多个对象被包含在样本中时，也能够实现能够优选地获取多个对象的图像的图像获取装置，图像获取方法和图像获取程序。

84. 发明申请

US20090264399A1 HETEROCYCLIC JANUS KINASE 3 INHIBITORS 失效
标题翻译：杂交种JANUS KINASE 3抑制剂
公开(公告)号：US20090264399A1
公开(公告)日：2009-10-22
申请号：US11995445
申请日：2006-07-13
申请人： Takayuki Inoue , Takashi Tojo , Masataka Morita , Yutaka Nakajima , Keiko Hatanaka , Shohei Shirakami , Hiroshi Sasaki , Akira Tanaka , Fumie Takahashi , Koichiro Mukoyoshi , Yasuyuki Higashi , Akira Okimoto , Takeshi Hondo , Hitoshi Sawada
发明人： Takayuki Inoue , Takashi Tojo , Masataka Morita , Yutaka Nakajima , Keiko Hatanaka , Shohei Shirakami , Hiroshi Sasaki , Akira Tanaka , Fumie Takahashi , Koichiro Mukoyoshi , Yasuyuki Higashi , Akira Okimoto , Takeshi Hondo , Hitoshi Sawada
IPC分类号： A61K31/437 , C07D471/04 , C07D413/14 , C07D471/14 , A61K31/5377 , A61K31/397 , A61P25/00 , A61P37/06 , A61P35/00 , A61P35/02 , A61P11/06
CPC分类号： C07D471/14 , C07D519/00
摘要： The invention relates to compound of the formula (I) or its salt, wherein —R1, —R2, —R3, —R4, —R5, -M-, —X— and —Y═ are as defined in the description, their use of as, medicament, the process for their preparation and use for the treatment of JAK3 mediated diseases.
摘要翻译：本发明涉及式（I）或其盐的化合物，其中-R1，-R2，-R3，-R4，-R5，-M-，-X-和-Y-如说明书中所定义，它们使用as，药物，其制备方法和用于治疗JAK3介导的疾病。

85. 发明申请

US20080174776A1 Fluorescence correlation spectroscopy analyzer 有权
标题翻译：荧光相关光谱分析仪
公开(公告)号：US20080174776A1
公开(公告)日：2008-07-24
申请号：US12000732
申请日：2007-12-17
申请人： Takayuki Inoue , Tadashi Maruno , Fumio Iwase
发明人： Takayuki Inoue , Tadashi Maruno , Fumio Iwase
IPC分类号： G01N21/64
CPC分类号： G01N21/6456 , G01J3/2803 , G01J3/2823 , G01J3/2889 , G01J3/4406 , G01J2003/2813 , G01J2003/282 , G01N21/645 , G01N2021/6417 , G01N2021/6423 , H04N5/3454 , H04N5/372
摘要： A fluorescence correlation spectroscopy analyzer 1 is equipped with an excitation light illuminating optical system 21, a fluorescence imaging optical system 22, a CCD camera 15, and a data analyzer 16. The excitation light illuminating optical system 21 illuminates excitation light onto a predetermined region of a measured sample S. The fluorescence imaging optical system 22 images the fluorescence generated at the measured sample S onto the photodetection surface of the CCD camera 15. The CCD camera 15 performs photoelectric conversion of the fluorescence made incident onto the photodetection surface in accordance with the respective pixels and outputs the charges generated by the photoelectric conversion as detection signals from an output terminal. The data analyzer 16 inputs the detection signals based on the charges generated at the pixels, among the pixels of the CCD camera 15, that belong to an analyzed pixel set and computes autocorrelation functions of the input detection signals according to each pixel. A fluorescence correlation spectroscopy analyzer, which is enabled to perform fluorescence correlation spectroscopy analysis on multiple points of a measured sample simultaneously and at high speed, is thus provided.
摘要翻译：荧光相关光谱分析仪1配备有激发光照明光学系统21，荧光成像光学系统22，CCD照相机15和数据分析器16.激发光照射光学系统21将激发光照射到测量样品S.荧光成像光学系统22将在测量样品S处产生的荧光图像成像到CCD照相机15的光电检测表面上。CCD照相机15根据照相机15对入射到光电检测表面上的荧光进行光电转换并输出由光电转换产生的电荷作为来自输出端的检测信号。数据分析器16基于在CCD摄像机15的像素中产生的属于分析像素组的像素产生的电荷输入检测信号，并根据每个像素计算输入检测信号的自相关函数。因此，提供了可以同时进行高速度地对多个点进行荧光相关光谱分析的荧光相关光谱分析仪。

86. 发明申请

US20060229236A1 Cyclic tetrapeptide compound and use thereof 审中-公开
标题翻译：环状四肽化合物及其用途
公开(公告)号：US20060229236A1
公开(公告)日：2006-10-12
申请号：US10500113
申请日：2002-12-27
申请人： Shigeki Satoh , Yasuharu Urano , Kazuhiko Osoda , Mitsuru Hosaka , Kozo Sawada , Takayuki Inoue , Hiroaki Mori , Shoji Takagaki , Takao Fujimura , Hideaki Matsuoka , Katsuhiko Yoshizawa
发明人： Shigeki Satoh , Yasuharu Urano , Kazuhiko Osoda , Mitsuru Hosaka , Kozo Sawada , Takayuki Inoue , Hiroaki Mori , Shoji Takagaki , Takao Fujimura , Hideaki Matsuoka , Katsuhiko Yoshizawa
IPC分类号： A61K38/12 , C07K5/12
CPC分类号： C07K5/126 , A61K38/12
摘要： A cyclic tetrapeptide compound of the formula (I): wherein R1 is hydrogen; R2 is lower alkyl, aryl, optionally substituted ar(lower)alkyl, heterocyclic(lower)alkyl, cyclo(lower)alkyl(lower)alkyl, lower alkylcarbamoyl(lower)alkyl or arylcarbamoyl(lower)alkyl; R3 and R4 are each independently hydrogen, lower alkyl, optionally substituted ar(lower)alkyl, optionally substituted heterocyclic(lower)alkyl or cyclo(lower)alkyl(lower)alkyl, or R3 and R4 are linked together to form lower alkylene or condensed ring, or one of R3 and R4 is linked to the adjacent nitrogen atom to form a ring; R5 is lower alkylene or lower alkenylene, Y is [wherein RY1 is hydrogen, halogen or optionally protected hydroxy, RY2 is hydrogen, halogen, lower alkyl or phenyl, and RY3 is hydrogen or lower alkyl]; R8 is hydrogen or lower alkyl; and n is an integer of 1 or 2, or a salt thereof.
摘要翻译：式（I）的环状四肽化合物：其中R 1是氢; R 2是低级烷基，芳基，任选取代的芳（低级）烷基，杂环（低级）烷基，环（低级）烷基（低级）烷基，低级烷基氨基甲酰基（低级）烷基或芳基氨基甲酰基烷基; R 3和R 4各自独立地为氢，低级烷基，任选取代的芳（低级）烷基，任选取代的杂环（低级）烷基或环（低级）烷基（低级））烷基或R 3和R 4连接在一起形成低级亚烷基或稠环，或者R 3和R 3中的一个 > 4 与相邻的氮原子连接形成环; R 5是低级亚烷基或低级亚烯基，Y是[其中R Y1是氢，卤素或任选保护的羟基，R Y2是氢，卤素，低级烷基或苯基，R 3 Y 3是氢或低级烷基]。 R 8是氢或低级烷基; n为1或2的整数，或其盐。

87. 发明申请

US20060076576A1 High electron mobility epitaxial substrate 有权
标题翻译：高电子迁移率外延衬底
公开(公告)号：US20060076576A1
公开(公告)日：2006-04-13
申请号：US10540514
申请日：2003-12-19
申请人： Takenori Osada , Takayuki Inoue , Noboru Fukuhara
发明人： Takenori Osada , Takayuki Inoue , Noboru Fukuhara
IPC分类号： H01L31/0328 , H01L21/336
CPC分类号： H01L29/7785
摘要： A compound semiconductor epitaxial substrate for use in a strain channel high electron mobility field effect transistor, comprising an InGaAs layer as a strain channel layer 6 and AlGaAs layers containing n-type impurities as back side and front side electron supplying layers 3 and 9, wherein an emission peak wavelength from the strain channel layer 6 at 77 K is set to 1030 nm or more by optimizing the In composition and the thickness of the strain channel layer 6.
摘要翻译：一种用于应变通道高电子迁移率场效应晶体管的化合物半导体外延基板，包括作为应变通道层6的InGaAs层和包含n型杂质的AlGaAs层作为背面侧和前侧电子供给层3和9，其中通过优化应变通道层6的In组成和厚度，将77K处的应变通道层6的发射峰值波长设定为1030nm以上。

88. 发明授权

US06955585B2 Curved surface machining method and an apparatus thereof 失效
标题翻译：曲面加工方法及其装置
公开(公告)号：US06955585B2
公开(公告)日：2005-10-18
申请号：US10934293
申请日：2004-09-03
申请人： Mamoru Mitsuishi , Shinichi Warisawa , Kouichi Kuramoto , Takayuki Inoue
发明人： Mamoru Mitsuishi , Shinichi Warisawa , Kouichi Kuramoto , Takayuki Inoue
IPC分类号： B24C3/00 , B24C1/04 , B24C3/22 , B24C5/02 , B24C7/00 , B24C1/08
CPC分类号： B24C1/04 , B24C3/22 , B24C5/02 , B24C7/0007
摘要： A curved surface machining method that performs finishing of the surface of a workpiece into a curved surface. The method includes the steps of: setting a workpiece in a rotating or stationary state in a water tank filled with an abrasive-containing solution into which an abrasive with a grain size of less than 1 μm has been admixed; and spraying a high-speed fluid in the abrasive-containing solution while a position, direction, and angle thereof is controlled relative to the workpiece, thus grinding and finishing the surface of the workpiece to an intended surface roughness and profile accuracy.
摘要翻译：一种曲面加工方法，其将工件的表面精加工成曲面。该方法包括以下步骤：在填充有磨料的溶液的水箱中将旋转或静止状态的工件设置在其中混合了粒度小于1μm的磨料的混合物; 并将高速流体喷射到含磨料的溶液中，同时相对于工件控制其位置，方向和角度，从而将工件的表面研磨和精加工到预期的表面粗糙度和轮廓精度。

89. 发明申请

US20050095955A1 Curved surface machining method and an apparatus thereof 失效
公开(公告)号：US20050095955A1
公开(公告)日：2005-05-05
申请号：US10934293
申请日：2004-09-03
申请人： Mamoru Mitsuishi , Shinichi Warisawa , Kouichi Kuramoto , Takayuki Inoue
发明人： Mamoru Mitsuishi , Shinichi Warisawa , Kouichi Kuramoto , Takayuki Inoue
IPC分类号： B24C3/00 , B24C1/04 , B24C3/22 , B24C5/02 , B24C7/00 , B24B49/00 , B24C1/00
CPC分类号： B24C1/04 , B24C3/22 , B24C5/02 , B24C7/0007
摘要： A curved surface machining method that performs finishing of the surface of a workpiece into a curved surface. The method includes the steps of: setting a workpiece in a rotating or stationary state in a water tank filled with an abrasive-containing solution into which an abrasive with a grain size of less than 1 μm has been admixed; and spraying a high-speed fluid in the abrasive-containing solution while a position, direction, and angle thereof is controlled relative to the workpiece, thus grinding and finishing the surface of the workpiece to an intended surface roughness and profile accuracy.

90. 发明授权

US06582351B1 Imidazopyridinone derivatives and their use as phosphodiesterase inhibitors 失效
标题翻译：咪唑并吡啶酮衍生物及其作为磷酸二酯酶抑制剂的用途
公开(公告)号：US06582351B1
公开(公告)日：2003-06-24
申请号：US10030979
申请日：2002-01-16
申请人： Kozo Sawada , Takayuki Inoue , Yuki Sawada , Tsuyoshi Mizutani
发明人： Kozo Sawada , Takayuki Inoue , Yuki Sawada , Tsuyoshi Mizutani
IPC分类号： A61K31435
CPC分类号： C07D401/04 , C07D235/26 , C07D235/28 , C07D401/12 , C07D403/04 , C07D405/04 , C07D405/12 , C07D471/04
摘要： A compound (Ia): wherein the variables are defined in the specification, its prodrug or a pharmaceutically acceptable salt thereof useful in the treatment of angina, hypertension etc.
摘要翻译：化合物（Ia）：其中变量在说明书中定义，其前药或其药学上可接受的盐可用于治疗心绞痛，高血压等。

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