专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

81. 发明专利

CH628894A5 VERFAHREN ZUM HERSTELLEN VON NEUEN BENZO(A) CHINOLIZIDIN-DERIVATEN. 未知
公开(公告)号：CH628894A5
公开(公告)日：1982-03-31
申请号：CH320081
申请日：1981-05-15
申请人： CHINOIN GYOGYSZER ES VEGYESZET
发明人： SZANTAY CSABA , SZABO LAJOS , TOEKE LASZLO , TOTH ISTVAN , VIRAG SANDOR , KANYO ERZSEBET , DAVID AGOSTON
IPC分类号： C07D455/06 , C07D491/056 , C07D491/14 , C07D455/03

82. 发明专利

RO73522A 未知
公开(公告)号：RO73522A
公开(公告)日：1981-11-04
申请号：RO8855576
申请日：1976-11-25
申请人： CHINOIN GYOGYSZER ES VEGYESZET
发明人： MESZAROS ZOLTAN , KNOLL JOSZEF , SZENTMIKLOSI PETER , HERMECZ ISTVAN , HORVATH AGNES , VIRAG SANDOR , VASVARI ARPADNE , DAVID AGOSTON
IPC分类号： A61K31/505 , A61K31/519 , A61P7/02 , A61P25/04 , A61P29/00 , A61P43/00 , C07D471/04 , C07D239/70
摘要： Antiphlogistic and anticoagulant compounds of the formula: wherein m is 0, 1 or 2, n is 0, 1 or 2, R is C1 to C6 alkyl, R1 is hydrogen, or C1 to C6 alkyl, R2 is hydrogen, C1 to C6 alkyl, substituted or unsubstituted amino, substituted or unsubstituted hydroxy, carboxy or a group derived from a carboxylic acid or R1 and R2 together form a -(CH=CH)2-group and R5 is 0 or imino or substituted imino.

83. 发明专利

CS203135B2 METHOD OF PRODUCING RACEMIC OR OPTICALLY ACTIVE PYRIMIDO/1,2A/HETEROCYCLIC COMPOUNDS 未知
公开(公告)号：CS203135B2
公开(公告)日：1981-02-27
申请号：CS766576
申请日：1976-11-26
申请人： CHINOIN GYOGYSZER ES VEGYESZET
发明人： MESZAROS ZOLTAN , KNOLL JOZSEF , SZENTMIKLOSI PETER , HERMECZ ISTVAN , HORVATH AGNES , VIRAG SANDOR , VASVARI LELLE , DAVID AGOSTON
IPC分类号： A61K31/505 , A61K31/519 , A61P7/02 , A61P25/04 , A61P29/00 , A61P43/00 , C07D471/04 , C07D487/04
摘要： Antiphlogistic and anticoagulant compounds of the formula: wherein m is 0, 1 or 2, n is 0, 1 or 2, R is C1 to C6 alkyl, R1 is hydrogen, or C1 to C6 alkyl, R2 is hydrogen, C1 to C6 alkyl, substituted or unsubstituted amino, substituted or unsubstituted hydroxy, carboxy or a group derived from a carboxylic acid or R1 and R2 together form a -(CH=CH)2-group and R5 is 0 or imino or substituted imino.

85. 发明专利

CS199288B2 METHOD OF PRODUCING NOVEL DERIVATIVES OF PYRIMIDINE 未知
公开(公告)号：CS199288B2
公开(公告)日：1980-07-31
申请号：CS97177
申请日：1977-02-14
申请人： CHINOIN GYOGYSZER ES VEGYESZET
发明人： HERMECZ ISTVAN , MESZAROS ZOLTAN , VIRAG SANDOR , VASVARI LELLE , HORVATH AGNES , KNOLL JOZSEF , SEBESTYEN GYULA , DAVID AGOSTON
IPC分类号： C07D487/04 , A61K31/505 , A61K31/519 , A61P3/06 , A61P9/10 , A61P25/28 , C07D471/04 , C07D239/70

86. 发明专利

CA1082699A FUSED PYRIMIDINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF 未知
公开(公告)号：CA1082699A
公开(公告)日：1980-07-29
申请号：CA271582
申请日：1977-02-11
申请人： CHINOIN GYOGYSZER ES VEGYESZET
发明人： HERMECZ ISTVAN , MESZAROS ZOLTAN , VIRAG SANDOR , VASVARI LELLE , HORVATH AGNES , KNOLL JOZSEF , SEBESTYEN GYULA , DAVID AGOSTON
IPC分类号： C07D487/04 , A61K31/505 , A61K31/519 , A61P3/06 , A61P9/10 , A61P25/28 , C07D471/04
摘要： This invention relates to a process for the preparation of new, optionally racemic or optically active fused pyrimidine derivatives of the general formula I (I) wherein m is 0 or 1; and if m = 0, then R is hydrogen or lower alkyl; R1 is hydrogen or R and R1 together form a group of the Formula -(CH=CH)2-in which case the dotted line is a further carbon-carbon bond while in all other cases between the positions linked by the dotted line there is only a single bond; R2 is hydrogen or hydroxy and R3 is hydrogen; or R2 is hydroxy and R3 is hydroxymethyl or R2 and R3 together form a valency bond; R6 is hydrogen; a phenyl group which may be optionally substituted by up to three atoms or groups selected from lower alkoxy, hydroxy, methylenedioxy, nitro, cyano, lower dialkylamino, lower alkanoylamino and halogen; trihalogenomethyl; a 5- or 6-membered monocyclic heteroaryl group containing one or two nitrogen atoms and/or 1 oxygen atom and which may be optionally substituted by lower alkyl or nitro; carboxy; or lower alkoxycarbonyl; R7 and R8 are hydrogen or together form a valency bond; R9 is hydrogen or hydroxy; R10 is hydrogen, phenyl, lower alkyl, carboxy, lower alkoxycarbonyl, cyano, methyliminomethyl, a carbamoyl group optionally substituted by one or two lower alkyl groups, a carboxylic acid hydrazido group, a group of the Formula -(CH2)q-COO-lower alkyl - wherein q is 1 or 2; or a group of the general Formula -CO-NH-N=R12 - wherein R12 is benzylidene, furfurylidene or nitrofurfurylidene; or R9 and R10 together form a group of the Formula -(CH2)p- wherein p = 3, 4, 5 or 6; n = 0 or 1 with the proviso that if n = 0, then R and R1 are hydrogen, R2 and R3 are hydrogen or together form a valency bond; R6 is phenyl or carboxy; R7 and R8 together form a valency bond; R9 is hydrogen and R10 is carboxy or lower alkoxycarbonyl; and if m = 1, then R is lower alkyl; R1 is hydrogen; R2 and R3 together form a valency bond; R4 and R5 together form a valency bond; R6 is phenyl or nitrophenyl; R7 and R8 together form a valency bond; R9 is hydrogen; R10 is carboxy or lower alkoxycarbonyl and n = 1. The new compounds possess valuable pharmaceutical properties, being especially effective against atherosclerosis, influencing not only the serum lipids, but also decreasing the quantity of the lipids and cholesterol deposited on the walls of the veins.

87. 发明专利

HU174693B PROCESS FOR PRODUCING CONDENSED PYRIMIDINE DERIVATIVES 未知
公开(公告)号：HU174693B
公开(公告)日：1980-03-28
申请号：HUCI001642
申请日：1976-02-12
申请人： CHINOIN GYOGYSZER ES VEGYESZET
发明人： HERMECZ ISTVAN , MESZAROS ZOLTAN , HORVATH AGNES , VIRAG SANDOR , VASVARI GEB DEBRECZY LELLE , KNOLL JOZSEF , SEBESTYEN GYULA , DAVID AGOSTON
IPC分类号： C07D487/04 , A61K31/505 , A61K31/519 , A61P3/06 , A61P9/10 , A61P25/28 , C07D471/04

88. 发明专利

NO792569L 未知
公开(公告)号：NO792569L
公开(公告)日：1980-02-05
申请号：NO792569
申请日：1979-08-03
申请人： CHINOIN GYOGYSZER ES VEGYESZET
发明人： SCHAWARTZ JOZSEF , DAVID AGOSTON , HORVATH GABOR
IPC分类号： A61K31/275 , A01N37/34 , A01N37/48 , A01N37/52 , A01N43/50 , A61K31/155 , A61K31/415 , A61P33/00 , C07C67/00 , C07C239/00 , C07C253/00 , C07C255/49 , C07C255/53 , C07C255/54 , C07C255/56 , C07C257/10 , C07C257/12 , C07C257/14 , C07D233/90 , C07C

89. 发明专利

CA1070681A LOCAL ANAESTHETIC SALTS AND A PROCESS FOR THE PREPARATION THEREOF 未知
公开(公告)号：CA1070681A
公开(公告)日：1980-01-29
申请号：CA268121
申请日：1976-12-17
申请人： CHINOIN GYOGYSZER ES VEGYESZET
发明人： SZEJTLI JOZSEF , DOSA EVA , TASSONYI EDOEMER , DAVID AGOSTON , NAGY ZSUZSANNA NEE BIRO
IPC分类号： C08B37/08
摘要： Water-soluble local anaesthetic compounds of sustained effect are prepared by reacting a chondroitin derivative with a basic local anaesthetic compound.

90. 发明专利

HU174116B METHOD AND DEVICE TO DETERMINE THE FLUIDITY CHARACTERISTICS GRANULAR SOLID MATTERS 未知
公开(公告)号：HU174116B
公开(公告)日：1979-11-28
申请号：HUCI001633
申请日：1975-12-29
申请人： CHINOIN GYOGYSZER ES VEGYESZET
发明人： DAVID AGOSTON , SZANISZLO KOCSARD , NAGY JANOS , ROENKOES LASZLO
IPC分类号： G01N11/02 , G01N33/00 , G01N11/04

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式