专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

71. 发明申请

US20070187592A1 High sensitivity slitless ion source mass spectrometer for trace gas leak detection 有权
标题翻译：高灵敏度无缝离子源质谱仪，用于痕量气体泄漏检测
公开(公告)号：US20070187592A1
公开(公告)日：2007-08-16
申请号：US11354737
申请日：2006-02-15
申请人： J. Geist , Jeffrey Diep , Peter Williams , Charles Perkins
发明人： J. Geist , Jeffrey Diep , Peter Williams , Charles Perkins
IPC分类号： H01J49/30 , H01J49/14
CPC分类号： H01J49/30 , H01J37/08 , H01J49/147
摘要： A mass spectrometer includes a main magnet having spaced-apart polepieces which define a gap, the main magnet producing a magnetic field in the gap, an ion source to generate ions and to accelerate the ions into the magnetic field in the gap, the ion source located outside the gap, and an ion detector to detect a selected species of the ions generated by the ion source and deflected by the magnetic field. The ion detector is located in the gap at a natural focus point of the selected species of ions. The mass spectrometer may be used in a trace gas leak detector.
摘要翻译：质谱仪包括具有限定间隙的间隔开的极点的主磁体，主磁体在间隙中产生磁场，离子源产生离子并将离子加速到间隙中的磁场中，离子源位于间隙之外，以及离子检测器，用于检测由离子源产生的并被磁场偏转的选定种类的离子。离子检测器位于所选离子种类的自然聚焦点的间隙中。质谱仪可用于痕量气体检漏仪。

72. 发明申请

US20070179196A1 Hiv integrase inhibitors 失效
标题翻译： Hiv整合酶抑制剂
公开(公告)号：US20070179196A1
公开(公告)日：2007-08-02
申请号：US10587682
申请日：2005-03-09
申请人： Wei Han , Melissa Egbertson , John Wai , Linghang Zhuang , Rowena Ruzek , Debra Perlow , Richard Isaacs , Mark Cameron , Bruce Foster , Ulf Dolling , R. Hoermer , Vanessa Obligado , Lou Neilson , Boyoung Kim , Linda Payne , Matthew Morrissette , Peter Williams , Philip Pye , Remy Angelaud , Danny Mancheno , David Askin
发明人： Wei Han , Melissa Egbertson , John Wai , Linghang Zhuang , Rowena Ruzek , Debra Perlow , Richard Isaacs , Mark Cameron , Bruce Foster , Ulf Dolling , R. Hoermer , Vanessa Obligado , Lou Neilson , Boyoung Kim , Linda Payne , Matthew Morrissette , Peter Williams , Philip Pye , Remy Angelaud , Danny Mancheno , David Askin
IPC分类号： A01N37/08
CPC分类号： C07D471/04
摘要： Hydroxy (tetra- or hexa-)hydronaphthyridine dione compounds of Formula I are inhibitors of HIV integrase and inhibitors of HIV replication: (I) wherein a, R,1?, R,2?, R,3?, R,4? and R,5? are defined herein. The compounds are useful in the prevention and treatment of infection by HIV and in the prevention, delay in the onset, and treatment of AIDS. The compounds are employed against HIV infection and AIDS as compounds per se or in the form of pharmaceutically acceptable salts. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.
摘要翻译：式I的羟基（四或六） - 氢化萘啶二酮化合物是HIV整合酶和HIV复制抑制剂的抑制剂：（I）其中a，R ，1？，R 2？R ，3？，R ，4？并且R ，5？在本文中定义。这些化合物可用于预防和治疗艾滋病毒感染以及预防，延迟艾滋病的发病和治疗。这些化合物用作抗感染和艾滋病作为化合物本身或以药学上可接受的盐的形式。化合物及其盐可以用作药物组合物中的成分，任选与其它抗病毒剂，免疫调节剂，抗生素或疫苗组合使用。

73. 发明授权

US07209892B1 Electronic music/media distribution system 失效
标题翻译：电子音乐/媒体分发系统
公开(公告)号：US07209892B1
公开(公告)日：2007-04-24
申请号：US09471971
申请日：1999-12-23
申请人： Albhy Galuten , Dmitry Radbel , Peter Williams
发明人： Albhy Galuten , Dmitry Radbel , Peter Williams
IPC分类号： G06Q30/00
CPC分类号： G06Q30/0603 , G06F21/10 , G06Q30/0625 , G06Q30/0643
摘要： An electronic media distribution system which facilitates the distribution of media to consumers over a network, such as the Internet, while achieving commercial business objectives and protecting the intellectual property rights associated with the media being distributed. The system provides the infrastructure and support for various market participants to engage in buying, selling, finding and distributing music. The system provides an interface for consumers to locate, access and receive musical content over the Internet. The system facilitates continued control over the musical content sent to consumers by dynamically enforcing retailer agreements and restrictions governing the purchase, use, and distribution of the content. The system also provides a service to retailers and distributors in assisting with the management of sales and distribution of music over the Internet. Specifically, the system certifies and distributes retail offers for the content where the offers are dynamically updated by electronic contracts between the retailers and distributors of the music.
摘要翻译：一种电子媒体分发系统，其有助于通过诸如因特网的网络向消费者分发媒体，同时实现商业业务目标并保护与被分发的媒体相关联的知识产权。该系统为各种市场参与者提供基础设施和支持，从事购买，销售，发现和发行音乐。该系统为消费者提供了通过互联网定位，访问和接收音乐内容的界面。该系统通过动态地实施零售商协议和管理内容的购买，使用和分发的限制来促进对发送给消费者的音乐内容的持续控制。该系统还为零售商和分销商提供服务，以协助管理互联网上音乐的销售和分销。具体来说，系统通过零售商和音乐经销商之间的电子合同动态更新优惠的内容来认证和分发零售优惠。

74. 发明申请

US20060270062A1 MASS SPECTROMETRIC IMMUNOASSAY 审中-公开
公开(公告)号：US20060270062A1
公开(公告)日：2006-11-30
申请号：US11462504
申请日：2006-08-04
申请人： Randall Nelson , Peter Williams , Jennifer Krone
发明人： Randall Nelson , Peter Williams , Jennifer Krone
IPC分类号： G01N33/543 , G01N33/00
CPC分类号： G01N24/00 , C12Q1/6816 , C12Q1/6872 , G01N33/5302 , G01N33/54373 , G01N33/6851 , Y10T436/24
摘要： Rapid mass spectrometric immunoassay methods for detecting and/or quantifying antibody and antigen analytes utilizing affinity capture to isolate the analytes and internal reference species (for quantification) followed by mass spectrometric analysis of the isolated analyte/internal reference species. Quantification is obtained by normalizing and calibrating obtained mass spectrum against the mass spectrum obtained for an antibody/antigen of known concentration.

75. 发明申请

US20060230496A1 Protection attachment for a safety helmet 有权
标题翻译：安全帽的保护附件
公开(公告)号：US20060230496A1
公开(公告)日：2006-10-19
申请号：US11377093
申请日：2006-03-16
申请人： Simon Husbands , Sergio Sequiera , Peter Williams
发明人： Simon Husbands , Sergio Sequiera , Peter Williams
IPC分类号： A42B1/04
CPC分类号： A42B3/105 , A42B3/22
摘要： A safety construction helmet is provided with an attachment which extends over the top of the helmet and provides sun protection.
摘要翻译：安全施工头盔设有一个在头盔顶部延伸并提供防晒功能的附件。

76. 发明申请

US20060138190A1 Pill splitter 失效
标题翻译：药丸分离器
公开(公告)号：US20060138190A1
公开(公告)日：2006-06-29
申请号：US11093734
申请日：2005-03-30
申请人： Peter Williams
发明人： Peter Williams
IPC分类号： B65H35/10 , B26B17/00
CPC分类号： A61J7/0007 , Y10T83/04 , Y10T225/10 , Y10T225/30 , Y10T225/329 , Y10T225/371
摘要： A tablet splitter includes a tablet bed having a bed body with a tablet holding structure for holding a tablet. A base is included having a base side wall with an outer perimeter. The side wall surrounds a recess extending along a longitudinal axis. The recess is shaped for receiving and retaining the bed body of the tablet bed. A cap having a cap side wall engages and slides over the outer perimeter of the base side wall along the longitudinal axis. The cap has an interior with a first splitting member positioned therein for engaging and splitting tablets held by the tablet bed.
摘要翻译：片剂分离器包括具有用于保持片剂的具有片剂保持结构的床体的片剂床。包括具有具有外周边的基侧壁的底座。侧壁围绕沿着纵向轴线延伸的凹部。该凹部成形为用于接收和保持片剂床的床体。具有帽侧壁的盖子沿着纵向轴线接合并在基座侧壁的外周上滑动。盖具有内部，其中定位有第一分裂构件，用于接合和分离由片剂床保持的片剂。

77. 发明申请

US20060049632A1 Tube fitting for stainless steel tubing 失效
标题翻译：管件适用于不锈钢管材
公开(公告)号：US20060049632A1
公开(公告)日：2006-03-09
申请号：US10467241
申请日：2002-02-06
申请人： Peter Williams
发明人： Peter Williams
IPC分类号： F16L13/14
CPC分类号： F16L19/14 , F16L19/10
摘要： A tube fitting that uses only two components, namely a fitting body and a fitting nut. The nut and body are adapted to be threadably coupled together by relative rotation therebetween. The nut includes an integral tube gripping ring that cooperates with a camming surface on the body when the fitting is made-up. The camming surface preferably has a steep camming angle. The ring is radially compressed against the tube outer wall to form a seal and a tight tube grip. The ring also forms a line contact-type seal against the camming surface. The ring is designed to have a hinging action and to plastically deform during pull-up to embed into the tubing for excellent tube grip, and an axially adjacent swage or col let zone that isolates any stress riser resulting from the embedding action from vibration effects. The fitting components, and particularly the ring, may be case hardened, the fitting may include a self-gauging feature to indicate sufficient pull-up to prevent excessive pull-up. Also provided is a single ferrule tube fitting that uses a steep camming surface and is at least about 3.3 times harder than the stainless steel tube end.
摘要翻译：仅使用两个部件的管接头，即接头体和接头螺母。螺母和本体适于通过它们之间的相对旋转而螺纹连接在一起。螺母包括一体的管夹环，当配件组装时，其与主体上的凸轮表面配合。凸轮表面优选具有陡峭的凸轮角度。环围绕管外壁径向压缩以形成密封和紧密的管夹。该环也形成针对凸轮表面的线接触型密封。该环被设计成具有铰接作用并且在上拉期间塑性变形以嵌入到用于优异管夹的管道中，以及轴向相邻的模具或排放区，其将由嵌入作用产生的任何应力提升器与振动效应隔离开。装配部件，特别是环可以是表面硬化的，配件可以包括自我测量特征，以指示足够的上拉以防止过度的上拉。还提供了使用陡峭的凸轮表面并且比不锈钢管端硬度至少约3.3倍的单个套圈管接头。

78. 发明申请

US20060012169A1 Tube fitting with tube gripping ring and sealant 失效
标题翻译：管接头与管夹环和密封剂
公开(公告)号：US20060012169A1
公开(公告)日：2006-01-19
申请号：US10518869
申请日：2003-09-18
申请人： Peter Williams
发明人： Peter Williams
IPC分类号： F16L47/00
CPC分类号： F16L19/14 , Y10T29/49428
摘要： A tube fitting (50) that uses two basic components, namely a fitting body (54) and a fitting nut (52). The nut (52) and body (54) are adapted to be threadably coupled together by relative rotation therebetween. The nut (52) includes an integral tube gripping ring (80) that may be separable from the nut upon pull-up of the fitting. The tube gripping ring and nut (52) form a trepan in which a sealant (400) is disposed.
摘要翻译：一种管接头（50），其使用两个基本部件，即配合体（54）和配合螺母（52）。螺母（52）和主体（54）适于通过它们之间的相对旋转而螺纹连接在一起。螺母（52）包括一体的管夹紧环（80），当套管上拉时，可以与螺母分离。管夹环和螺母（52）形成了一个配置有密封剂（400）的托盘。

79. 发明申请

US20050256676A1 Ultrasonic testing of fitting assembly for fluid conduits with a hand-held apparatus 失效
标题翻译：用手持式设备对流体管道的接头组件进行超声波检测
公开(公告)号：US20050256676A1
公开(公告)日：2005-11-17
申请号：US10518337
申请日：2003-06-17
申请人： Richard Ales , William Glime , John Hull , Jeffrey Rubinski , Michael Seymour , Peter Williams , Wenxian Yang
发明人： Richard Ales , William Glime , John Hull , Jeffrey Rubinski , Michael Seymour , Peter Williams , Wenxian Yang
IPC分类号： G01N29/00 , G01B5/14 , G01N29/04 , G01N29/11 , G01N29/24 , G01N29/28 , G01N29/46
CPC分类号： G01N29/043 , G01N29/11 , G01N29/2462 , G01N29/2468 , G01N29/28 , G01N29/46 , G01N2291/02491 , G01N2291/0422 , G01N2291/0423 , G01N2291/044 , G01N2291/056 , G01N2291/2634 , G01N2291/2691
摘要： Hand-held apparatus and method for determining relative and/or absolute axial position of a conduit end within a fluid coupling includes application of input ultrasonic energy in the form of transient shear waves and analyzing the reflected energy. Application of the input energy collected at different radial positions about a first axial location is used with wavelet based correlation techniques to better analyze the reflected energy signals. Quality of the abutment between the conduit end and a surface associated with the coupling may also be determined as a separate or combined feature of the axial position determination.
摘要翻译：用于确定流体联接器内的导管端的相对和/或绝对轴向位置的手持装置和方法包括以瞬态剪切波形式施加输入超声能量并分析反射能量。使用基于小波的相关技术来应用在围绕第一轴向位置的不同径向位置处收集的输入能量以更好地分析反射的能量信号。导管端与与联接件相关联的表面之间的邻接的质量也可以被确定为轴向位置确定的单独或组合的特征。

80. 发明申请

US20050153311A1 Mass spectrometric immunoassay analysis of specific proteins and variants present in various biological fluids 失效
标题翻译：对各种生物液体中存在的特定蛋白质和变体的质谱免疫分析
公开(公告)号：US20050153311A1
公开(公告)日：2005-07-14
申请号：US10958867
申请日：2004-10-04
申请人： Randall Nelson , Peter Williams , Jennifer Krone
发明人： Randall Nelson , Peter Williams , Jennifer Krone
IPC分类号： C12Q1/68 , G01N33/53 , G01N33/543
CPC分类号： C12Q1/6816 , C12Q1/6872 , G01N33/5302 , G01N33/54373 , Y10T436/24
摘要： Presented herein is the construction of pipettor tips (termed MSIA-Tips) containing porous solid supports that are constructed, covalently derivatized with affinity ligand, and used to extract specific proteins and their variants from various biological fluids by repeatedly flowing the fluids through the MSIA-Tips. A second protein species (a mass-shifted variant of the targeted protein doped into the samples at a constant concentration) is co-extracted with the endogenous protein and variants and is used as a quantitative internal reference standard (IRS). Nonspecifcally bound compounds are rinsed from the MSIA-Tip using a series of buffer and water rinses, after which the wild type protein, protein variants and the IRS are eluted from the MSIA-Tips directly onto a target in preparation for analysis such as MALDI-TOF. Mass spectrometry of the eluted sample then follows with the retained proteins identified via accurate molecular mass determination. Protein and variant levels are determined via a quantitative method in which the protein/variant signals are normalized to the signal of the IRS and the values compared to a working curve constructed from samples containing known concentrations of the protein or variants.
摘要翻译：这里提出的是构建含有多孔固体支持物的移液器尖端（称为MSIA-Tips），其构建为用亲和配体共价衍生，并且用于通过重复地使流体流过MSIA-DNA来从各种生物流体中提取特异性蛋白质及其变体，提示。将第二种蛋白质物种（以恒定浓度掺入样品中的靶向蛋白质的质量转移变体）与内源蛋白质和变体共萃取并用作定量内部参照标准品（IRS）。使用一系列缓冲液和水冲洗从MSIA-Tip中冲洗非特异性结合的化合物，之后将野生型蛋白质，蛋白质变体和IRS直接从MSIA-Tip中洗脱到靶上用于分析，如MALDI- TOF。洗脱的样品的质谱随后通过精确的分子量测定鉴定的保留的蛋白质。通过定量方法测定蛋白质和变体水平，其中将蛋白质/变体信号归一化为IRS的信号，并且该值与由含有已知浓度的蛋白质或变体的样品构建的工作曲线相比较。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式