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71. 发明授权

US08655458B2 Conformal electrodes for shaped medical device lead body segments 有权
标题翻译：用于成形医疗器械引线体段的保形电极
公开(公告)号：US08655458B2
公开(公告)日：2014-02-18
申请号：US12541461
申请日：2009-08-14
申请人： Bruce A. Tockman , Timothy R. Jackson , Brendan E. Koop , Lili Liu , Kimberly A. Morris , David J. Parins
发明人： Bruce A. Tockman , Timothy R. Jackson , Brendan E. Koop , Lili Liu , Kimberly A. Morris , David J. Parins
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N2001/0585
摘要： A medical lead includes a lead body having at least one conductor extending from a proximal end of the lead body to a distal end of the lead body. The proximal end is adapted to be connected to a pulse generator, and the distal end includes a curved portion. One or more electrodes are operatively connected to the at least one conductor and coupled to the curved portion of the lead body. At least a portion of each of the one or more electrodes includes an arrangement of interconnected, spaced-apart elements that are selectively configured to allow the one or more electrodes to conform to contours of the curved portion during and after implantation of the medical lead.
摘要翻译：医疗用引线包括具有至少一个导体的引线体，导体从引线主体的近端延伸到引线主体的远端。近端适于连接到脉冲发生器，并且远端包括弯曲部分。一个或多个电极可操作地连接到至少一个导体并且耦合到引线主体的弯曲部分。一个或多个电极中的每一个的至少一部分包括互连的间隔开的元件的布置，其被选择性地配置成允许一个或多个电极在植入医疗引线期间和之后使其符合弯曲部分的轮廓。

72. 发明申请

US20130172973A1 NEURAL STIMULATION DEVICE WITH INSULATING SHEATH 审中-公开
标题翻译：神经刺激装置与绝育
公开(公告)号：US20130172973A1
公开(公告)日：2013-07-04
申请号：US13728366
申请日：2012-12-27
申请人： Bruce A. Tockman , Brian D. Soltis , Lili Liu , Eric F. Hammill
发明人： Bruce A. Tockman , Brian D. Soltis , Lili Liu , Eric F. Hammill
IPC分类号： A61N1/05
CPC分类号： A61N1/0556 , A61N1/36053
摘要： Described is a stimulation electrode assembly for stimulation of a vagus nerve within a carotid sheath. The stimulation electrode assembly comprises an insulating sheath and at least one energy delivery element. The insulating sheath includes a flexible sheet of electrically insulative material configured to assume a generally tubular shape to at least partially surround the carotid sheath when implanted, and having a first side and a second side, wherein the first side is positionable toward the carotid sheath when implanted. The at least one energy delivery element is located on the first side of the insulating sheath and is configured to deliver energy to the vagus nerve when implanted.
摘要翻译：描述了一种用于刺激颈动脉鞘内迷走神经的刺激电极组件。刺激电极组件包括绝缘护套和至少一个能量输送元件。绝缘护套包括柔性的电绝缘材料片，其构造成呈现大致管状形状，以便在植入时至少部分地围绕颈动脉鞘，并且具有第一侧和第二侧，其中第一侧可朝向颈动脉鞘定位，植入。所述至少一个能量传递元件位于所述绝缘护套的第一侧上，并且被配置为在植入时将能量传递到迷走神经。

73. 发明申请

US20120130396A1 PEEL-AWAY IS-4/DF-4 LEAD IMPLANT TOOL WITH ELECTRICAL CONTACTS 有权
标题翻译： PEEL-AWAY IS-4 / DF-4铅电动工具与电气接触
公开(公告)号：US20120130396A1
公开(公告)日：2012-05-24
申请号：US13253336
申请日：2011-10-05
申请人： Bruce A. Tockman , Timothy R. Jackson , Peter J. Wolf
发明人： Bruce A. Tockman , Timothy R. Jackson , Peter J. Wolf
IPC分类号： A61B17/00
CPC分类号： A61N1/05 , A61N1/375 , H01R2201/12
摘要： A peel-away lead implant tool is described. The peel away lead implant tool is adapted to be disposed over the terminal connector of a lead during an implantation procedure to protect the terminal connector. The peel-away lead implant tool includes a flexible polymer sheath including electrical contacts formed in a contact region of the sheath. The electrical contacts can be either metal foil contacts or conductive polymer contacts and extend from an outer surface to an inner surface of the sheath such that when the testing apparatus is coupled to the lead implant tool, the electrical contacts are pressed into electrical contact with the ring electrodes located on the terminal connector. The lead implant tool also includes various removal means facilitating the easy removal of the implant tool from the terminal connector when the implantation procedure is complete.
摘要翻译：描述了一个剥离的铅离子植入工具。剥离引线植入工具适于在植入过程期间设置在引线的端子连接器上以保护端子连接器。剥离引线植入工具包括柔性聚合物护套，其包括形成在护套的接触区域中的电触点。电触点可以是金属箔触点或导电聚合物触点，并且从护套的外表面延伸到内表面，使得当测试装置耦合到引线注入工具时，电触点被压入与电接触位于端子连接器上的环形电极。引线植入工具还包括各种移除装置，当植入程序完成时便于从终端连接器容易地移除植入物工具。

74. 发明申请

US20120022617A1 MINIMALLY INVASIVE LEAD SYSTEM FOR VAGUS NERVE STIMLATION 有权
标题翻译：用于VAGUS神经刺激的最小入侵引导系统
公开(公告)号：US20120022617A1
公开(公告)日：2012-01-26
申请号：US13186203
申请日：2011-07-19
申请人： Bruce A. Tockman , Juan Gabriel Hincapie Ordonez , Lili Liu
发明人： Bruce A. Tockman , Juan Gabriel Hincapie Ordonez , Lili Liu
IPC分类号： A61N1/372
CPC分类号： A61N1/36114 , A61N1/0556 , A61N1/0558 , A61N1/36185
摘要： A system including two neurostimulation leads can be used for stimulating a select region of a nerve within a nerve bundle. For example, two leads can be used to stimulate a select region of the vagus nerve located within a patient's carotid sheath. The first neurostimulation is positioned within the carotid sheath and the second neurostimulation lead is positioned external to the carotid sheath. Each of the first and second neurostimulation leads includes at least one electrode defining an electrode array about the select region of the nerve. The electrode array, and more particularly, the different possible electrode vector combinations provided by the first and second neurostimulation leads facilitate steering of stimulation current density fields as needed or desired between the electrodes to effectively and efficiently treat a particular medical, psychiatric, or neurological disorder.
摘要翻译：包括两个神经刺激引线的系统可用于刺激神经束内的神经的选择区域。例如，可以使用两个引线来刺激位于患者颈动脉鞘内的迷走神经的选择区域。第一神经刺激位于颈动脉鞘内，第二神经刺激引线位于颈动脉鞘外。第一和第二神经刺激引线中的每一个包括限定围绕神经的选择区域的电极阵列的至少一个电极。电极阵列，更具体地，由第一和第二神经刺激引线提供的不同的可能的电极向量组合有助于在电极之间根据需要或期望的刺激电流密度场的转向，以有效和有效地治疗特定的医学，精神病学或神经障碍。

75. 发明授权

US08052731B2 Medical electrical lead with expandable fixation features 失效
标题翻译：具有可扩展固定功能的医用电线
公开(公告)号：US08052731B2
公开(公告)日：2011-11-08
申请号：US11422000
申请日：2006-06-02
申请人： Brian D. Soltis , Bruce A. Tockman , Kent C. B. Stalker , Eric T. Johnson , Peter J. D'Aquanni
发明人： Brian D. Soltis , Bruce A. Tockman , Kent C. B. Stalker , Eric T. Johnson , Peter J. D'Aquanni
IPC分类号： A61F2/06 , A61N1/05
CPC分类号： A61N1/057 , A61B18/1492 , A61B2017/00243
摘要： A medical electrical lead adapted to be at least partially implanted in a cardiac vessel includes a fixation feature operable to change from an undeployed configuration to a deployed configuration in which the fixation feature is adapted to engage an inner surface of the cardiac vessel. A tendon is disposed within a lumen of the lead and is operatively connected to the fixation feature and adapted to cause the fixation feature to change from the undeployed configuration to the deployed configuration for acute and/or chronic fixation of the lead. In one embodiment, the fixation feature includes a deflectable region of the lead which in the deployed configuration causes a surface of the lead body to engage the inner surface of the cardiac vessel. In another embodiment, the fixation feature includes a radially expandable structure for engaging the inner surface of the vessel in the deployed configuration.
摘要翻译：适于至少部分地植入心脏血管的医用电线包括固定特征，其可操作以从未部署的构型改变为展开构造，其中固定特征适于接合心脏血管的内表面。腱设置在引导件的内腔中并且可操作地连接到固定特征并且适于使固定特征从未部署的构型改变为用于引导的急性和/或慢性固定的展开配置。在一个实施例中，固定特征包括引线的可偏转区域，其在展开构型中引起引线主体的表面接合心脏血管的内表面。在另一个实施例中，固定特征包括用于在展开构型中接合容器内表面的径向可扩展结构。

76. 发明授权

US08019438B2 Anchor for electrode delivery system 有权
标题翻译：电极传输系统的锚点
公开(公告)号：US08019438B2
公开(公告)日：2011-09-13
申请号：US11168282
申请日：2005-06-28
申请人： Eric T. Johnson , Bruce A. Tockman
发明人： Eric T. Johnson , Bruce A. Tockman
IPC分类号： A61N1/00 , A61B5/00
CPC分类号： A61N1/057 , A61F2/86 , A61F2/95 , A61N2001/0585
摘要： The present invention is device for delivering an electrode into a lateral vein of the coronary sinus. The device includes a support structure, a stent, a tether coupled to the stent and a removable sheath disposed about the stent. The stent is carried on the support structure and is deployable from a first collapsed configuration to a second expanded configuration for engaging the inner walls of the selected vessel. The sheath is sized to retain the stent in the first collapsed configuration. The electrode is carried on the stent or on a lead threaded over the tether.
摘要翻译：本发明是用于将电极输送到冠状窦的侧静脉中的装置。该装置包括支撑结构，支架，联接到支架的系绳和围绕支架设置的可移除的护套。支架承载在支撑结构上，并且可从第一折叠构造展开到第二扩张构型，用于接合所选容器的内壁。护套的尺寸设计成将支架保持在第一折叠构型。电极被携带在支架上或者穿过系绳上的导线上。

77. 发明授权

US07765015B2 Lead with inflatable fixation mechanism 失效
标题翻译：带充气固定机构
公开(公告)号：US07765015B2
公开(公告)日：2010-07-27
申请号：US11622810
申请日：2007-01-12
申请人： Eric T. Johnson , Brian D. Soltis , Bruce A. Tockman , Peter J. D'aquanni , Kent C. B. Stalker , Gayla A. Smith
发明人： Eric T. Johnson , Brian D. Soltis , Bruce A. Tockman , Peter J. D'aquanni , Kent C. B. Stalker , Gayla A. Smith
IPC分类号： A61N1/05
CPC分类号： A61N1/057 , A61M25/04 , A61M25/10 , A61N2001/0585
摘要： A medical electrical lead configured for use in stimulating the left side of the heart (i.e., the left ventricle). In one embodiment, the lead includes an elongate lead body including an inner surface. An inflatable member is disposed on the outer surface of the body between its proximal and distal ends, the inflatable member being adapted when inflated to impart a radial force on and frictionally engage a surface of the coronary sinus or coronary vein for fixation of the distal end of the lead therein. The lead further includes a conductive member extending from the proximal end toward the distal end, and an inner insulating layer positioned between the conductive member and the inner surface of the body. Separation between the inner insulating layer and the inner surface of the body defines an inflation lumen in fluid communication with the inflatable member.
摘要翻译：构造成用于刺激心脏左侧（即，左心室）的医用电线。在一个实施例中，引线包括包括内表面的细长引线主体。可膨胀构件设置在身体的近端和远端之间的外表面上，所述可膨胀构件适于在膨胀时赋予径向力并摩擦地接合冠状窦或冠状静脉的表面以固定远端的铅。引线还包括从近端朝向远端延伸的导电构件，以及位于导电构件和主体内表面之间的内绝缘层。内绝缘层和本体内表面之间的分离限定了与可膨胀构件流体连通的膨胀腔。

78. 发明授权

US07747334B2 Left ventricular lead shapes 有权
标题翻译：左心室铅形
公开(公告)号：US07747334B2
公开(公告)日：2010-06-29
申请号：US11277326
申请日：2006-03-23
申请人： Mark J. Bly , Brian D. Soltis , Bruce A. Tockman , Avram Scheiner
发明人： Mark J. Bly , Brian D. Soltis , Bruce A. Tockman , Avram Scheiner
IPC分类号： A61N1/372
CPC分类号： A61N1/056 , A61N2001/0585
摘要： A lead for sensing and pacing a left ventricle of the heart includes a lead body having a proximal portion and a distal portion, a lumen extending through the lead body, a conductor extending through the lead body from the proximal end to the distal end and an electrode disposed on the distal portion of the lead body and electrically coupled to the conductor. A distal tip of the lead body is continuously deflectable upon advancement and withdrawal of a stylet through the lumen at the distal portion to access a selected branch of the coronary sinus. The distal tip of the lead body may be offset before or after continuously deflecting the distal tip.
摘要翻译：用于感测和起搏心脏左心室的引线包括具有近端部分和远端部分的引线体，延伸穿过引线主体的内腔，从近端延伸穿过引线主体到远端的导体，以及电极，其设置在引线体的远端部分上并电耦合到导体。引导体的远侧末端在通过远端部分的内腔前进和取出探针时可连续偏转，以进入冠状窦的选定分支。引线体的远端可以在连续偏转远端之前或之后偏移。

79. 发明申请

US20100010608A1 Guide Wire Stylet 有权
标题翻译：导丝导管
公开(公告)号：US20100010608A1
公开(公告)日：2010-01-14
申请号：US12564731
申请日：2009-09-22
申请人： Bruce A. Tockman , Frank Vandeputte , Muralidharan Srivathsa , Randy Westlund
发明人： Bruce A. Tockman , Frank Vandeputte , Muralidharan Srivathsa , Randy Westlund
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N2001/0585
摘要： A cardiac lead system includes a cardiac lead having a lumen, and a guide member displaceable within the lumen. The guide member includes a guide wire extension that extends distal to the elongated body of the guide member. The guide wire extension is dimensioned to pass through an external distal opening of the cardiac lead lumen. Engagement of stop features or a stop mechanism of the cardiac lead system provides a push point for advancing the cardiac lead system through the patient's anatomy.
摘要翻译：心脏引导系统包括具有内腔的心脏引线和可在内腔内移位的引导部件。引导构件包括在引导构件的细长主体的远侧延伸的导丝延伸部。引导线延伸部的尺寸设计成穿过心脏引流管腔的外部远端开口。心脏引导系统的停止特征或停止机制的接合为心脏引导系统通过患者的解剖结构提供了推动点。

80. 发明授权

US07610105B2 Methods of using a guide wire stylet 失效
标题翻译：使用导丝探针的方法
公开(公告)号：US07610105B2
公开(公告)日：2009-10-27
申请号：US11432950
申请日：2006-05-12
申请人： Bruce A. Tockman , Frank Vandeputte , Muralidharan Srivathsa , Randy Westlund
发明人： Bruce A. Tockman , Frank Vandeputte , Muralidharan Srivathsa , Randy Westlund
IPC分类号： A61N1/00
CPC分类号： A61N1/056 , A61N2001/0585
摘要： Methods facilitate inserting a cardiac lead into a patient's vasculature. A cardiac lead system includes a cardiac lead having a lumen, and a guide member displaceable within the lumen. The guide member includes a guide wire extension that extends distal to the elongated body of the guide member. The guide wire extension is dimensioned to pass through an external distal opening of the cardiac lead lumen. Engagement of stop features or a stop mechanism of the cardiac lead system provides a push point for advancing the cardiac lead system through the patient's anatomy.
摘要翻译：方法便于将心脏铅插入病人的脉管系统。心脏引导系统包括具有内腔的心脏引线和可在内腔内移位的引导部件。引导构件包括在引导构件的细长主体的远侧延伸的导丝延伸部。引导线延伸部的尺寸设计成穿过心脏引流管腔的外部远端开口。心脏引导系统的停止特征或停止机制的接合为心脏引导系统通过患者的解剖结构提供了推动点。

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