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1. 发明申请

US20080172118A1 LEAD WITH INFLATABLE FIXATION MECHANISM 失效
标题翻译：具有可充气的固定机构
公开(公告)号：US20080172118A1
公开(公告)日：2008-07-17
申请号：US11622810
申请日：2007-01-12
申请人： Eric T. Johnson , Brian D. Soltis , Bruce A. Tockman , Peter J. D'Aquanni , Kent C. B. Stalker , Gayla A. Smith
发明人： Eric T. Johnson , Brian D. Soltis , Bruce A. Tockman , Peter J. D'Aquanni , Kent C. B. Stalker , Gayla A. Smith
IPC分类号： A61N1/05
CPC分类号： A61N1/057 , A61M25/04 , A61M25/10 , A61N2001/0585
摘要： A medical electrical lead configured for use in stimulating the left side of the heart (i.e., the left ventricle). In one embodiment, the lead includes an elongate lead body including an inner surface. An inflatable member is disposed on the outer surface of the body between its proximal and distal ends, the inflatable member being adapted when inflated to impart a radial force on and frictionally engage a surface of the coronary sinus or coronary vein for fixation of the distal end of the lead therein. The lead further includes a conductive member extending from the proximal end toward the distal end, and an inner insulating layer positioned between the conductive member and the inner surface of the body. Separation between the inner insulating layer and the inner surface of the body defines an inflation lumen in fluid communication with the inflatable member.
摘要翻译：构造成用于刺激心脏左侧（即，左心室）的医用电引线。在一个实施例中，引线包括包括内表面的细长引线主体。可膨胀构件设置在身体的近端和远端之间的外表面上，所述可膨胀构件适于在膨胀时赋予径向力并摩擦地接合冠状窦或冠状静脉的表面，用于固定远端的铅。引线还包括从近端朝向远端延伸的导电构件，以及位于导电构件和主体内表面之间的内绝缘层。内绝缘层和本体内表面之间的分离限定了与可膨胀构件流体连通的膨胀腔。

2. 发明授权

US07765015B2 Lead with inflatable fixation mechanism 失效
标题翻译：带充气固定机构
公开(公告)号：US07765015B2
公开(公告)日：2010-07-27
申请号：US11622810
申请日：2007-01-12
申请人： Eric T. Johnson , Brian D. Soltis , Bruce A. Tockman , Peter J. D'aquanni , Kent C. B. Stalker , Gayla A. Smith
发明人： Eric T. Johnson , Brian D. Soltis , Bruce A. Tockman , Peter J. D'aquanni , Kent C. B. Stalker , Gayla A. Smith
IPC分类号： A61N1/05
CPC分类号： A61N1/057 , A61M25/04 , A61M25/10 , A61N2001/0585
摘要： A medical electrical lead configured for use in stimulating the left side of the heart (i.e., the left ventricle). In one embodiment, the lead includes an elongate lead body including an inner surface. An inflatable member is disposed on the outer surface of the body between its proximal and distal ends, the inflatable member being adapted when inflated to impart a radial force on and frictionally engage a surface of the coronary sinus or coronary vein for fixation of the distal end of the lead therein. The lead further includes a conductive member extending from the proximal end toward the distal end, and an inner insulating layer positioned between the conductive member and the inner surface of the body. Separation between the inner insulating layer and the inner surface of the body defines an inflation lumen in fluid communication with the inflatable member.
摘要翻译：构造成用于刺激心脏左侧（即，左心室）的医用电线。在一个实施例中，引线包括包括内表面的细长引线主体。可膨胀构件设置在身体的近端和远端之间的外表面上，所述可膨胀构件适于在膨胀时赋予径向力并摩擦地接合冠状窦或冠状静脉的表面以固定远端的铅。引线还包括从近端朝向远端延伸的导电构件，以及位于导电构件和主体内表面之间的内绝缘层。内绝缘层和本体内表面之间的分离限定了与可膨胀构件流体连通的膨胀腔。

3. 发明授权

US08442656B2 Cardiac lead having implantable stiffening structures for fixation 有权
标题翻译：心脏导联具有可植入的硬化结构用于固定
公开(公告)号：US08442656B2
公开(公告)日：2013-05-14
申请号：US11422014
申请日：2006-06-02
申请人： Bruce A. Tockman , Brian D. Soltis , Eric T. Johnson , Kent C. B. Stalker , Peter J. D'aquanni , Paul E. Zarembo
发明人： Bruce A. Tockman , Brian D. Soltis , Eric T. Johnson , Kent C. B. Stalker , Peter J. D'aquanni , Paul E. Zarembo
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/0573 , A61N2001/0585
摘要： A cardiac lead adapted for fixation at least partially within a cardiac vessel. The lead includes, in one embodiment, an elongate lead body defining a proximal region and a distal region including a distal end region having at least one electrode and a distal tip. The distal end region is configured such that the electrode and the distal tip can be implanted in the cardiac vessel. Stiffening structures in the distal region of the lead are adapted to stiffen selected portions of the lead for fixation of the electrode within the cardiac vessel. In some embodiments, the stiffening structures include an implantable member adapted to be implanted in a lumen of the lead. In other embodiments, the stiffening structures include a sheath adapted to be deployed over the lead body. In still other embodiments, the stiffening structures are integral to the lead and/or the lead body.
摘要翻译：适于至少部分地固定在心脏血管内的心脏引线。在一个实施例中，引线包括限定近端区域的细长引线体和包括具有至少一个电极和远端尖端的远端区域的远侧区域。远端区域被构造成使得电极和远端尖端可以植入心脏血管。铅的远端区域中的加强结构适于加强导线的选定部分，以将电极固定在心脏血管内。在一些实施例中，加强结构包括适于植入在引导管腔中的可植入部件。在其他实施例中，加强结构包括适于部署在引线主体上的护套。在其他实施例中，加强结构与引线和/或引线主体成一体。

4. 发明申请

US20070282414A1 MEDICAL ELECTRICAL LEAD WITH EXPANDABLE FIXATION FEATURES 失效
标题翻译：具有可扩充固定功能的医用电气引线
公开(公告)号：US20070282414A1
公开(公告)日：2007-12-06
申请号：US11422000
申请日：2006-06-02
申请人： Brian D. Soltis , Bruce A. Tockman , Kent C. B. Stalker , Eric T. Johnson , Peter J. D'Aquanni
发明人： Brian D. Soltis , Bruce A. Tockman , Kent C. B. Stalker , Eric T. Johnson , Peter J. D'Aquanni
IPC分类号： A61N1/05
CPC分类号： A61N1/057 , A61B18/1492 , A61B2017/00243
摘要： A medical electrical lead adapted to be at least partially implanted in a cardiac vessel includes a fixation feature operable to change from an undeployed configuration to a deployed configuration in which the fixation feature is adapted to engage an inner surface of the cardiac vessel. A tendon is disposed within a lumen of the lead and is operatively connected to the fixation feature and adapted to cause the fixation feature to change from the undeployed configuration to the deployed configuration for acute and/or chronic fixation of the lead. In one embodiment, the fixation feature includes a deflectable region of the lead which in the deployed configuration causes a surface of the lead body to engage the inner surface of the cardiac vessel. In another embodiment, the fixation feature includes a radially expandable structure for engaging the inner surface of the vessel in the deployed configuration.
摘要翻译：适于至少部分地植入心脏血管的医用电线包括固定特征，其可操作以从未部署的构型改变为展开构造，其中固定特征适于接合心脏血管的内表面。腱设置在引导件的内腔中并且可操作地连接到固定特征并且适于使固定特征从未部署的构型改变为用于引导的急性和/或慢性固定的展开配置。在一个实施例中，固定特征包括引线的可偏转区域，其在展开构型中引起引线主体的表面接合心脏血管的内表面。在另一个实施例中，固定特征包括用于在展开构型中接合容器内表面的径向可扩展结构。

5. 发明申请

US20070293922A1 MEDICAL ELECTRICAL LEAD WITH FRICTION-ENHANCING FIXATION FEATURES 有权
标题翻译：具有摩擦增强固定特性的医用电线
公开(公告)号：US20070293922A1
公开(公告)日：2007-12-20
申请号：US11424349
申请日：2006-06-15
申请人： Brian D. Soltis , Bruce A. Tockman , Kent C. B. Stalker , Eric T. Johnson , Peter J. D'Aquanni
发明人： Brian D. Soltis , Bruce A. Tockman , Kent C. B. Stalker , Eric T. Johnson , Peter J. D'Aquanni
IPC分类号： A61N1/00
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/0585
摘要： Medical electrical leads are provided including fixation features for acute and chronic fixation of a portion of the respective leads within the cardiac venous system. The medical electrical lead includes an elongate body having proximal and distal regions. Tissue contacting portions are selectively located in the distal region to contact an inner surface of the cardiac vessel when the lead is in an implanted position. The tissue contacting portion(s) include fixation features adapted to frictionally engage the inner surface of the cardiac vessel and promote tissue in-growth for chronic fixation. In some embodiments, the fixation features are detachable from the lead such that the lead can be extracted from its implanted position after tissue in-growth occurs.
摘要翻译：提供了医疗电引线，其包括用于心脏静脉系统内的各个引线的一部分的急性和慢性固定的固定特征。医疗电线包括具有近端和远端区域的细长体。当引线处于植入位置时，组织接触部分选择性地位于远端区域中以接触心脏血管的内表面。组织接触部分包括适于摩擦地接合心脏血管的内表面并促进用于慢性固定的组织生长的固定特征。在一些实施例中，固定特征可从铅脱离，使得在组织生长发生之后，引线可以从其植入位置提取。

6. 发明授权

US07890174B2 Medical electrical lead with deployable fixation features 失效
标题翻译：医用电线带有可部署的固定功能
公开(公告)号：US07890174B2
公开(公告)日：2011-02-15
申请号：US11421990
申请日：2006-06-02
申请人： Brian D. Soltis , Bruce A. Tockman , Kent C. B. Stalker , Eric T. Johnson , Peter J. D'Aquanni
发明人： Brian D. Soltis , Bruce A. Tockman , Kent C. B. Stalker , Eric T. Johnson , Peter J. D'Aquanni
IPC分类号： A61N1/36
CPC分类号： A61N1/0573 , A61B18/1492 , A61N1/056 , A61N2001/0585
摘要： A medical electrical lead adapted to be at least partially implanted in a cardiac vessel includes a fixation feature operable to change from an undeployed configuration to a deployed configuration in which the fixation feature is adapted to engage an inner surface of the cardiac vessel. A tendon is disposed within a lumen of the lead and is operatively connected to the fixation feature and adapted to cause the fixation feature to change from the undeployed configuration to the deployed configuration for acute and/or chronic fixation of the lead. In one embodiment, the fixation feature includes a deflectable region of the lead which in the deployed configuration causes a surface of the lead body to engage the inner surface of the cardiac vessel. In another embodiment, the fixation feature includes a radially expandable structure for engaging the inner surface of the vessel in the deployed configuration.
摘要翻译：适于至少部分地植入心脏血管的医用电线包括固定特征，其可操作以从未部署的构型改变为展开构造，其中固定特征适于接合心脏血管的内表面。腱设置在引导件的内腔中并且可操作地连接到固定特征并且适于使固定特征从未部署的构型改变为用于引导的急性和/或慢性固定的展开配置。在一个实施例中，固定特征包括引线的可偏转区域，其在展开构型中引起引线主体的表面接合心脏血管的内表面。在另一个实施例中，固定特征包括用于在展开构型中接合容器内表面的径向可扩展结构。

7. 发明授权

US07725197B2 Medical electrical lead with friction-enhancing fixation features 有权
标题翻译：具有摩擦增强固定功能的医用电线
公开(公告)号：US07725197B2
公开(公告)日：2010-05-25
申请号：US11424349
申请日：2006-06-15
申请人： Brian D. Soltis , Bruce A. Tockman , Kent C. B. Stalker , Eric T. Johnson , Peter J. D'Aquanni
发明人： Brian D. Soltis , Bruce A. Tockman , Kent C. B. Stalker , Eric T. Johnson , Peter J. D'Aquanni
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/0585
摘要： Medical electrical leads are provided including fixation features for acute and chronic fixation of a portion of the respective leads within the cardiac venous system. The medical electrical lead includes an elongate body having proximal and distal regions. Tissue contacting portions are selectively located in the distal region to contact an inner surface of the cardiac vessel when the lead is in an implanted position. The tissue contacting portion(s) include fixation features adapted to frictionally engage the inner surface of the cardiac vessel and promote tissue in-growth for chronic fixation. In some embodiments, the fixation features are detachable from the lead such that the lead can be extracted from its implanted position after tissue in-growth occurs.
摘要翻译：提供了医疗电引线，其包括用于心脏静脉系统内的各个引线的一部分的急性和慢性固定的固定特征。医疗电线包括具有近端和远端区域的细长体。当引线处于植入位置时，组织接触部分选择性地位于远端区域中以接触心脏血管的内表面。组织接触部分包括适于摩擦地接合心脏血管的内表面并促进用于慢性固定的组织生长的固定特征。在一些实施例中，固定特征可从铅脱离，使得在组织生长发生之后，引线可以从其植入位置提取。

8. 发明授权

US08052731B2 Medical electrical lead with expandable fixation features 失效
标题翻译：具有可扩展固定功能的医用电线
公开(公告)号：US08052731B2
公开(公告)日：2011-11-08
申请号：US11422000
申请日：2006-06-02
申请人： Brian D. Soltis , Bruce A. Tockman , Kent C. B. Stalker , Eric T. Johnson , Peter J. D'Aquanni
发明人： Brian D. Soltis , Bruce A. Tockman , Kent C. B. Stalker , Eric T. Johnson , Peter J. D'Aquanni
IPC分类号： A61F2/06 , A61N1/05
CPC分类号： A61N1/057 , A61B18/1492 , A61B2017/00243
摘要： A medical electrical lead adapted to be at least partially implanted in a cardiac vessel includes a fixation feature operable to change from an undeployed configuration to a deployed configuration in which the fixation feature is adapted to engage an inner surface of the cardiac vessel. A tendon is disposed within a lumen of the lead and is operatively connected to the fixation feature and adapted to cause the fixation feature to change from the undeployed configuration to the deployed configuration for acute and/or chronic fixation of the lead. In one embodiment, the fixation feature includes a deflectable region of the lead which in the deployed configuration causes a surface of the lead body to engage the inner surface of the cardiac vessel. In another embodiment, the fixation feature includes a radially expandable structure for engaging the inner surface of the vessel in the deployed configuration.
摘要翻译：适于至少部分地植入心脏血管的医用电线包括固定特征，其可操作以从未部署的构型改变为展开构造，其中固定特征适于接合心脏血管的内表面。腱设置在引导件的内腔中并且可操作地连接到固定特征并且适于使固定特征从未部署的构型改变为用于引导的急性和/或慢性固定的展开配置。在一个实施例中，固定特征包括引线的可偏转区域，其在展开构型中引起引线主体的表面接合心脏血管的内表面。在另一个实施例中，固定特征包括用于在展开构型中接合容器内表面的径向可扩展结构。

9. 发明申请

US20070282413A1 CARDIAC LEAD HAVING STIFFENING STRUCTURES FOR FIXATION 审中-公开
标题翻译：具有固定结构的CARDIAC引线
公开(公告)号：US20070282413A1
公开(公告)日：2007-12-06
申请号：US11422012
申请日：2006-06-02
申请人： Bruce A. Tockman , Brian D. Soltis , Eric T. Johnson , Kent C. B. Stalker , Peter J. D' aquanni , Paul E. Zarembo
发明人： Bruce A. Tockman , Brian D. Soltis , Eric T. Johnson , Kent C. B. Stalker , Peter J. D' aquanni , Paul E. Zarembo
IPC分类号： A61N1/05
CPC分类号： A61N1/057 , A61N2001/0585
摘要： A cardiac lead adapted for fixation at least partially within a cardiac vessel. The lead includes, in one embodiment, an elongate lead body defining a proximal region and a distal region including a distal end region having at least one electrode and a distal tip. The distal end region is configured such that the electrode and the distal tip can be implanted in the cardiac vessel. Stiffening structures in the distal region of the lead are adapted to stiffen selected portions of the lead for fixation of the electrode within the cardiac vessel. In some embodiments, the stiffening structures include an implantable member adapted to be implanted in a lumen of the lead. In other embodiments, the stiffening structures include a sheath adapted to be deployed over the lead body. In still other embodiments, the stiffening structures are integral to the lead and/or the lead body.
摘要翻译：适于至少部分地固定在心脏血管内的心脏引线。在一个实施例中，引线包括限定近端区域的细长引线体和包括具有至少一个电极和远端尖端的远端区域的远侧区域。远端区域被构造成使得电极和远端尖端可以植入心脏血管。铅的远端区域中的加强结构适于加强导线的选定部分，以将电极固定在心脏血管内。在一些实施例中，加强结构包括适于植入在引导管腔中的可植入部件。在其他实施例中，加强结构包括适于部署在引线主体上的护套。在其他实施例中，加强结构与引线和/或引线主体成一体。

10. 发明申请

US20080071339A1 MECHANISM FOR RELEASABLY ENGAGING AN IMPLANTABLE MEDICAL DEVICE FOR IMPLANTATION 有权
标题翻译：用于植入可植入医疗器械用于植入的机构
公开(公告)号：US20080071339A1
公开(公告)日：2008-03-20
申请号：US11855501
申请日：2007-09-14
申请人： Kent C. B. Stalker , Peter J. D'Aquanni , Eric T. Johnson
发明人： Kent C. B. Stalker , Peter J. D'Aquanni , Eric T. Johnson
IPC分类号： A61N1/05
CPC分类号： A61B5/0215 , A61B5/6876 , A61B2560/066 , A61M25/0074 , A61N1/05 , A61N2001/0578
摘要： An apparatus for releasably engaging an implantable medical device during delivery includes an elongate, tubular body having an open distal end a plurality of deflectable jaw members extending distally from the distal end of the body and terminating in distal tip portions, and an actuating member slidably disposed within the body and including a distal end portion operable to prevent inward deflection of the jaw members when positioned proximate the distal tip portions. The jaw members are adapted to releasably engage an engagement feature of the implantable medical device.
摘要翻译：一种用于在输送过程中可释放地接合植入式医疗装置的装置包括细长的管状体，其具有开放的远端，多个可偏转的钳口构件从主体的远端向远侧延伸并且终止于远侧末端部分，以及可滑动地设置的致动构件并且包括远端部分，其可操作以防止当邻近远侧末端部分定位时夹爪构件向内偏转。钳口构件适于可释放地接合可植入医疗装置的接合特征。

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