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71. 发明授权

US07195591B2 Device to permit offpump beating heart coronary bypass surgery 有权
标题翻译：允许偏心跳动心脏冠状动脉旁路手术的装置
公开(公告)号：US07195591B2
公开(公告)日：2007-03-27
申请号：US11063478
申请日：2005-02-23
申请人： Paul A. Spence , Warren P. Williamson, IV
发明人： Paul A. Spence , Warren P. Williamson, IV
IPC分类号： A61B17/00
CPC分类号： A61B17/02 , A61B17/0206 , A61B17/0218 , A61B2017/0243 , A61B2017/306 , A61B2017/308
摘要： A heart retractor links lifting of the heart and regional immobilization which stops one part of the heart from moving to allow expeditious suturing while permitting other parts of the heart to continue to function whereby coronary surgery can be performed on a beating heart while maintaining cardiac output unabated and uninterrupted. Circumflex coronary artery surgery can be performed using the heart retractor of the present invention. The retractor includes a plurality of flexible arms and a plurality of rigid arms as well as a surgery target immobilizing element. One form of the retractor can be used in minimally invasive surgery, while other forms of the retractor can accommodate variations in heart size and paracardial spacing.
摘要翻译：心脏牵开器连接心脏的抬起和区域性固定，其阻止心脏的一部分移动以允许快速缝合，同时允许心脏的其他部分继续发挥作用，从而可以在跳动的心脏上进行冠状动脉手术，同时保持心输出量不减并不间断。可以使用本发明的心脏牵开器进行环形冠状动脉手术。牵开器包括多个柔性臂和多个刚性臂以及手术目标固定元件。牵开器的一种形式可用于微创手术，而其他形式的牵开器可以适应心脏尺寸和心包间隔的变化。

72. 发明授权

US07156814B1 Apparatus and method for harvesting and handling tissue samples for biopsy analysis 有权
标题翻译：收集和处理组织样本用于活检分析的装置和方法
公开(公告)号：US07156814B1
公开(公告)日：2007-01-02
申请号：US09890177
申请日：1998-10-05
申请人： Warren P. Williamson, IV , Stephen Whitlach , Dominic DiNovo , Douglas Allen , Thomas Ward
发明人： Warren P. Williamson, IV , Stephen Whitlach , Dominic DiNovo , Douglas Allen , Thomas Ward
IPC分类号： A61B10/00 , G01N1/30 , G01N33/48 , C12M1/12 , C12M1/22 , C12M3/00
CPC分类号： G01N1/36 , A61B10/0096 , G01N1/06 , G01N1/312 , G01N2001/315
摘要： A sectional cassette (10) for use in a process for harvesting and handling tissue samples for biopsy analysis is disclosed. In the procedure, a tissue biopsy sample is placed on a tissue trapping supporting material (A′) that can withstand tissue preparation procedures, and which can be cut with a microtome. The tissue is immobilized on the material, and the material and the tissue are held in the cassette (10) subjected to a process for replacing tissue fluids with wax. The tissue and supporting material are sliced for mounting on slides using a microtome. Harvesting devices and containers (200) using the filter material (202) are disclosed. An automated process is also disclosed.
摘要翻译：公开了一种用于采集和处理组织样本用于活组织检查分析的方法的分段盒（10）。在该过程中，将组织活检样品放置在可以承受组织制备程序的组织捕获支撑材料（A'）上，并且可以用切片机切割。将组织固定在材料上，并将材料和组织保持在经过用蜡代替组织液的过程的盒（10）中。使用切片机将组织和支撑材料切片以安装在载玻片上。公开了使用过滤材料（202）的收获装置和容器（200）。还公开了一种自动化过程。

73. 发明授权

US06652543B2 Means and method for performing an anastomosis 失效
标题翻译：用于进行吻合的手段和方法
公开(公告)号：US06652543B2
公开(公告)日：2003-11-25
申请号：US09892235
申请日：2001-06-26
申请人： Paul A. Spence , Warren P. Williamson, IV , George Christakis
发明人： Paul A. Spence , Warren P. Williamson, IV , George Christakis
IPC分类号： A61B1704
CPC分类号： A61B17/1152 , A61B17/11 , A61B2017/1135 , A61B2017/1139 , Y10S623/903
摘要： An anastomosis is performed using a mounting structure mounted on the outside of at least one vessel. The mounting structure includes a flexible mounting structure that is attached to the vessel by a special instrument. A graft vessel is attached to the mounting structure either directly or by means of another mounting structure attached to the graft vessel. Tools for attaching a mounting structure to a vessel are disclosed, and a tool for attaching two mounting structures together is also disclosed. Methods for carrying out the anastomosis according to the invention are also disclosed.
摘要翻译：使用安装在至少一个容器的外部的安装结构进行吻合。安装结构包括通过专用仪器附接到容器的柔性安装结构。移植物容器直接或通过附接到移植血管的另一安装结构附接到安装结构。公开了用于将安装结构附接到容器的工具，并且还公开了用于将两个安装结构连接在一起的工具。还公开了根据本发明的用于进行吻合的方法。

74. 发明授权

US06610072B1 Surgical loop delivery device 失效
标题翻译：手术环输送装置
公开(公告)号：US06610072B1
公开(公告)日：2003-08-26
申请号：US09722875
申请日：2000-11-27
申请人： William J. Christy , James R. Christy , Warren P. Williamson, IV , Craig Berky
发明人： William J. Christy , James R. Christy , Warren P. Williamson, IV , Craig Berky
IPC分类号： A61B1704
CPC分类号： A61B17/12013 , A61B17/0483 , A61B2017/303
摘要： A surgical loop delivery device is disclosed in parent disclosures Ser. No. 09/071,811 and U.S. Pat. No. 5,766,217. This device is improved to permit tissue targets larger than the device to be ligated while also maintaining a clear sight path between the surgeon and the target. The surgical loop is also stable during the procedure.
摘要翻译：外科手术环输送装置在母公开公报美国专利No.09 / 071,811和美国专利No. 第5,766,217号。该装置被改进以允许大于装置的组织靶标被连接，同时还保持外科医生和靶标之间的清晰的视线路径。手术过程中手术环路也是稳定的。

75. 发明授权

US06338712B2 Device to permit offpump beating heart coronary bypass surgery 失效
标题翻译：允许偏心跳动心脏冠状动脉旁路手术的装置
公开(公告)号：US06338712B2
公开(公告)日：2002-01-15
申请号：US09087511
申请日：1998-05-29
申请人： Paul A. Spence , Warren P. Williamson, IV , Mark Ortiz
发明人： Paul A. Spence , Warren P. Williamson, IV , Mark Ortiz
IPC分类号： A61B132
CPC分类号： A61B17/0218 , A61B17/00491 , A61B17/02 , A61B17/0206 , A61B17/0293 , A61B17/04 , A61B17/064 , A61B17/068 , A61B17/29 , A61B2017/00305 , A61B2017/00309 , A61B2017/0243 , A61B2017/308
摘要： A system for manipulating a heart during cardiac surgery permits coronary surgery on a beating heart while maintaining cardiac output unabated and uninterrupted. Circumflex coronary artery surgery can be performed using the system. The system locates a suspension head near the apical region of the heart and a gross support near the base of the heart near the AV groove. A frame is positioned within the patient's thoracic region and moves with the patient, and a surgical target immobilizer can be used to assist in the movement of the heart if desired. A special suction cup is used which accommodates multiplanar movement of the heart and the myocardium while also preventing heart tissue from interrupting the suction being applied to the heart. One form of the system can be used in minimally invasive surgery.
摘要翻译：在心脏手术期间操作心脏的系统允许在跳动心脏上进行冠状动脉手术，同时保持心输出量不变且不间断。 Circumflex冠状动脉手术可以使用系统进行。该系统位于心脏顶端附近的悬架头部，靠近AV凹槽附近靠近心脏底部的大体支撑。框架位于患者的胸部区域内并与患者一起移动，并且如果需要，可以使用外科手术目标固定器来辅助心脏的移动。使用特殊的吸盘，其容纳心脏和心肌的多平面运动，同时还防止心脏组织中断被施加到心脏的吸力。该系统的一种形式可用于微创手术。

76. 发明授权

US5709680A Electrosurgical hemostatic device 失效
标题翻译：电外科止血装置
公开(公告)号：US5709680A
公开(公告)日：1998-01-20
申请号：US362065
申请日：1994-12-22
申请人： David C. Yates , Jesse J. Kuhns , Warren P. Williamson, IV
发明人： David C. Yates , Jesse J. Kuhns , Warren P. Williamson, IV
IPC分类号： A61B17/00 , A61B17/072 , A61B17/115 , A61B17/32 , A61B18/12 , A61B18/14 , A61B19/00 , A61B17/36
CPC分类号： A61B17/115 , A61B17/07207 , A61B18/1206 , A61B18/1447 , A61B17/32 , A61B18/1402 , A61B2017/00504 , A61B2017/07214 , A61B2017/07228 , A61B2018/00404 , A61B2018/00601 , A61B2018/00642 , A61B2018/00666 , A61B2018/00672 , A61B2018/00678 , A61B2018/00684 , A61B2018/00702 , A61B2018/00708 , A61B2018/00875 , A61B2018/1273 , A61B2018/1861 , A61B2090/032
摘要： An electrosurgical instrument is provided for cauterization and/or welding of tissue of varying impedances, thicknesses and vascularity especially in the performance of endoscopic procedures. The instrument compresses the tissue in the compression zone between first interfacing surface and second interfacing surfaces. The compression zone is formed by an insulator which forms a compression ridge in one of the interfacing surfaces and separates first and second electrically opposite electrodes. A preferred application of the invention is in a cutting instrument wherein a hemostatic line is formed using RF along a cut line.
摘要翻译：提供了一种电外科手术器械，用于对变化的阻抗，厚度和血管的组织进行烧灼和/或焊接，特别是在内窥镜手术的执行中。仪器在第一接口表面和第二接口表面之间压缩压缩区域中的组织。压缩区由绝缘体形成，该绝缘体在一个接口表面中形成压缩脊，并分离第一和第二电相对的电极。本发明的优选应用在切割仪器中，其中使用沿着切割线的RF形成止血线。

77. 发明授权

US5360542A Centrifuge with separable bowl and spool elements providing access to the separation chamber 失效
标题翻译：用可分离的碗和卷轴元件离心，提供进入分离室的通道
公开(公告)号：US5360542A
公开(公告)日：1994-11-01
申请号：US147015
申请日：1993-11-02
申请人： Warren P. Williamson, IV , Richard I. Brown
发明人： Warren P. Williamson, IV , Richard I. Brown
IPC分类号： B04B5/00 , A61M1/30 , A61M1/36 , B01D17/02 , B01D21/24 , B01D21/26 , B04B5/04 , B04B7/08 , B04B13/00
CPC分类号： B04B13/00 , A61M1/302 , A61M1/303 , A61M1/308 , A61M1/3693 , A61M1/3696 , B01D17/0217 , B01D21/0003 , B01D21/2405 , B01D21/245 , B01D21/262 , B04B5/0442 , B04B7/08 , A61M1/30 , A61M2202/0427 , A61M2205/3344 , A61M2205/3351 , A61M2205/3355 , B01D2221/08 , B01D2221/10 , B04B2005/045
摘要： A centrifuge provides simplify access to the processing chamber. In one arrangement, the processing chamber separates into a bowl and spool element to receive a disposable processing bag. In another arrangement, the processing chamber pivots between an operating position and an access position to provide improved access. The centrifuge also employs readily accessible holders for releasably retaining tubing that, in use, conveys fluid to and from the chamber. Though greatly accessible, the centrifuge operates without the need of complicated rotating seals and expensive disposable components.
摘要翻译：离心机可简化进入处理室的通道。在一种布置中，处理室分成碗和卷轴元件以接收一次性处理袋。在另一种布置中，处理室在操作位置和进入位置之间枢转以提供改进的通路。离心机还采用易于接近的保持器，用于可释放地保持在使用中将流体输送到腔室的管道。虽然离合器很容易操作，但不需要复杂的旋转密封件和昂贵的一次性部件。

78. 发明授权

US08877146B2 Cassette for handling and holding tissue samples during processing, embedding and microtome procedures, and methods therefor 有权
标题翻译：用于在处理，嵌入和切片机程序期间处理和保持组织样品的盒，及其方法
公开(公告)号：US08877146B2
公开(公告)日：2014-11-04
申请号：US11618987
申请日：2007-01-02
申请人： Warren P. Williamson, IV , Thomas J. Ward , Stephen P. Whitlatch
发明人： Warren P. Williamson, IV , Thomas J. Ward , Stephen P. Whitlatch
IPC分类号： B01L9/00 , B01L3/00 , G01N1/31
CPC分类号： B01L3/545 , B01L2300/02 , G01N1/31 , G01N2001/315
摘要： A cassette for holding a tissue sample includes a body having a bottom wall and a plurality of side walls extending upwardly with respect to the bottom wall to define an interior space for receiving the tissue sample. A lid is configured to be received in the interior space, and the cassette is sectionable in a microtome. Sensing elements are associated with the body or lid and configured to allow an automated sensing system to determine at least one characteristic of the cassette. A flange extends along upper portions of at least two of the side walls and includes a plurality of holes. Other features are included to more effectively and efficiently manufacture and use the cassette.
摘要翻译：用于保持组织样本的盒包括具有底壁和相对于底壁向上延伸的多个侧壁的主体，以限定用于接收组织样本的内部空间。盖被配置为容纳在内部空间中，并且盒可在切片机中分段。感测元件与主体或盖相关联并且被配置为允许自动感测系统确定盒的至少一个特性。凸缘沿至少两个侧壁的上部延伸并且包括多个孔。包括其他功能，以更有效和高效地制造和使用磁带。

79. 发明申请

US20120203241A1 SINGLE PORT SURGICAL TISSUE CONTAINMENT AND EXTRACTION DEVICE 审中-公开
标题翻译：单端口外科组织包装和提取装置
公开(公告)号：US20120203241A1
公开(公告)日：2012-08-09
申请号：US13501540
申请日：2010-10-19
申请人： Warren P. Williamson, IV
发明人： Warren P. Williamson, IV
IPC分类号： A61B17/28
CPC分类号： A61B10/06 , A61B10/0096 , A61B17/29 , A61B2017/00287 , A61B2017/306
摘要： A tissue containment and extraction device including a tissue grasper configured to extend into a patient through an access site. The device includes jaws operative to grasp onto tissue to be extracted from the patient, and a tissue container having a distal end and a proximal end. The distal end of the grasper extends through the proximal end of the tissue container and is further operative to be extended through the distal end of the tissue container to grasp onto and pull the tissue proximally into the tissue container. A deployment structure is operatively coupled with the tissue container to allow a user to open the distal end of the container for receipt of the tissue and close the distal end of the container after the tissue is pulled into the tissue container. Related methods are also disclosed.
摘要翻译：一种组织容纳和提取装置，其包括构造成通过进入位置延伸到患者体内的组织抓取器。该装置包括可操作地抓住要从患者抽出的组织的钳口，以及具有远端和近端的组织容器。抓紧器的远端延伸穿过组织容器的近端，并进一步操作以延伸穿过组织容器的远端，以将组织向近侧抓紧并拉入组织容器中。部署结构与组织容器可操作地联接，以允许使用者打开容器的远端以接收组织，并在组织被拉入组织容器之后关闭容器的远端。还公开了相关方法。

80. 发明授权

US07905842B2 Apparatus and method for excising tissue and bandaging the resulting wound 失效
标题翻译：用于切除组织并包扎所得伤口的装置和方法
公开(公告)号：US07905842B2
公开(公告)日：2011-03-15
申请号：US11639098
申请日：2006-12-14
申请人： Warren P. Williamson, IV , Michael K. Banbury , Jillian E. Banbury
发明人： Warren P. Williamson, IV , Michael K. Banbury , Jillian E. Banbury
IPC分类号： A61B10/00
CPC分类号： A61B17/32093 , A61B10/02 , A61B17/08 , A61B17/085 , A61B17/32 , A61B17/3211 , A61B17/322 , A61B2010/0208 , A61B2017/00747 , A61B2017/00761 , A61B2017/00774 , A61B2017/081
摘要： An apparatus (10) and method for excising tissue (208) and closing a wound (156) that results from excision of the tissue (208) is provided. The apparatus (10) includes structure (14) defining an aperture (34) into which tissue (208) to be excised is exposed and a cutting member (96). The apparatus (10) also includes an adhesive bandage (140) for closing the wound (156). The adhesive bandage (140) is secured relative to a lower surface (20) of the structure (14) in a location for contacting skin (154) adjacent to the tissue (208) to be excised. The apparatus (10) further includes a device (150) that is actuatable for closing the wound (156) with the adhesive bandage (140) and actuators (108 and 182) for moving the cutting member (96) relative to the structure (14) for excising the tissue (208) exposed in the aperture (34) and for actuating the device (150).
摘要翻译：提供了一种用于切除组织（208）并关闭由组织（208）切除引起的伤口（156）的装置（10）和方法。装置（10）包括限定要被切除的组织（208）暴露的孔（34）的结构（14）和切割构件（96）。装置（10）还包括用于封闭伤口（156）的胶粘绷带（140）。粘合绷带（140）相对于结构（14）的下表面（20）固定在用于接触待切除的组织（208）的皮肤（154）的位置。装置（10）还包括一个装置（150），该装置可致动以用粘合绷带（140）和用于相对于结构（14）移动切割构件（96）的致动器（108和182）来闭合伤口），用于切除暴露在孔（34）中的组织（208）并用于致动装置（150）。

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