专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

71. 发明授权

US07668595B2 Cardiac rhythm management system with optimization of cardiac performance using heart rate 有权
标题翻译：心脏节律管理系统使用心率优化心脏性能
公开(公告)号：US07668595B2
公开(公告)日：2010-02-23
申请号：US11619391
申请日：2007-01-03
申请人： Rodney W. Salo , Kenneth L. Baker , Lawrence S. Baumann
发明人： Rodney W. Salo , Kenneth L. Baker , Lawrence S. Baumann
IPC分类号： A61N1/362
CPC分类号： A61N1/3702 , A61N1/3627 , A61N1/3682 , A61N1/3684 , A61N1/3688
摘要： A method of optimizing inter-site delay is disclosed for a cardiac rhythm management device that includes a dual chamber pacemaker, especially designed for treating congestive heart failure by pacing a plurality of sites. A microcontroller is operative to adjust the pacing mode and inter-site delay of the pacemaker so as to achieve optimum hemodynamic performance. Atrial cycle lengths measured during transient (immediate) time intervals following a change in the mode inter-site delay are signal processed and a determination can then be made as to which particular configuration yields the optimum performance. Performance is optimized when the patient is at rest and when the patient exercises so that a rate-adapted dynamic value of the optimum performance can be applied.
摘要翻译：公开了一种用于心脏节律管理装置的优化站间延迟的方法，其包括双室起搏器，其特别设计用于通过起搏多个部位来治疗充血性心力衰竭。微控制器可操作以调节起搏器的起搏模式和站间延迟，以达到最佳的血液动力学性能。信号处理后的瞬时（即时）时间间隔内测量的心房周期长度被信号处理，然后可以确定哪个特定配置产生最佳性能。当患者处于静止状态并且患者锻炼时优化性能，以便可以应用最佳性能的速率适应动态值。

72. 发明申请

US20100041984A1 Impedance sensing device and catheter system 审中-公开
标题翻译：阻抗传感器和导管系统
公开(公告)号：US20100041984A1
公开(公告)日：2010-02-18
申请号：US12228536
申请日：2008-08-12
申请人： James Edward Shapland , Christopher G. Quinn , Rodney W. Salo
发明人： James Edward Shapland , Christopher G. Quinn , Rodney W. Salo
IPC分类号： A61B5/055 , A61M25/10 , A61B5/05
CPC分类号： A61M25/10 , A61B5/053 , A61B5/489 , A61B5/6852 , A61M25/04 , A61M25/09 , A61M2025/09183 , A61M2025/1052 , A61M2210/125
摘要： A sensing system including a collection catheter and a sensing device. The sensing system can be used in determining an optimal location of a collection catheter for the removal of a medium from coronary circulation. The sensing system can also be used in determining the optimal time for the collection of blood containing a medium. The sensing system can further be used to maintain a baseline flow rate through at least a portion of the coronary circulation system during a medical procedure.
摘要翻译：一种感测系统，包括收集导管和感测装置。感测系统可以用于确定用于从冠状动脉循环中移除介质的收集导管的最佳位置。感测系统也可用于确定收集含有介质的血液的最佳时间。感测系统还可用于在医疗过程期间通过冠状循环系统的至少一部分来维持基线流速。

73. 发明申请

US20090171407A1 METHOD AND APPARATUS FOR MINIMIZING POST-INFARCT VENTRICULAR REMODELING 有权
标题翻译：用于最小化后腹腔镜重建的方法和装置
公开(公告)号：US20090171407A1
公开(公告)日：2009-07-02
申请号：US12396115
申请日：2009-03-02
申请人： Rodney W. Salo
发明人： Rodney W. Salo
IPC分类号： A61N1/368
CPC分类号： A61N1/3627 , A61N1/0587 , A61N1/3684
摘要： A cardiac rhythm management device for in which pre-excitation pacing is applied to one or more sites in proximity to an infarcted region of the ventricular myocardium. Such pacing servers to either prevent or minimize post-infarct remodeling.
摘要翻译：一种心律管理装置，其中预激发起搏应用于心室心肌梗塞区域附近的一个或多个部位。这种起搏服务器可以预防或最小化梗死后重塑。

74. 发明授权

US06640135B1 Apparatus and method for spatially and temporally distributing cardiac electrical stimulation 有权
标题翻译：空间和时间分布心脏电刺激的装置和方法
公开(公告)号：US06640135B1
公开(公告)日：2003-10-28
申请号：US09544363
申请日：2000-04-06
申请人： Rodney W. Salo , Julio C. Spinelli , Bruce H. KenKnight
发明人： Rodney W. Salo , Julio C. Spinelli , Bruce H. KenKnight
IPC分类号： A61N1368
CPC分类号： A61N1/368 , A61N1/3622 , A61N1/3627
摘要： A cardiac electro-stimulatory device and method for operating same in which stimulation pulses are distributed among a plurality of electrodes fixed at different sites of the myocardium in order to reduce myocardial hypertrophy brought about by repeated pacing at a single site and/or increase myocardial contractility. In order to spatially and temporally distribute the stimulation, the pulses are delivered through a switchable pulse output configuration during a single cardiac cycle, with each configuration comprising one or more electrodes fixed to different sites in the myocardium.
摘要翻译：一种心脏电刺激装置及其操作方法，其中刺激脉冲分布在固定在心肌不同部位的多个电极之间，以便通过在单个部位重复起搏而引起的心肌肥大和/或增加心肌收缩力。为了空间和时间地分布刺激，脉冲在单个心动周期期间通过可切换的脉冲输出配置递送，每个配置包括一个或多个电极固定在心肌中的不同部位。

75. 发明授权

US6044298A Optimization of pacing parameters based on measurement of integrated acoustic noise 失效
标题翻译：基于综合声学噪声测量优化起搏参数
公开(公告)号：US6044298A
公开(公告)日：2000-03-28
申请号：US170259
申请日：1998-10-13
申请人： Rodney W. Salo , Kevin G. Nugent
发明人： Rodney W. Salo , Kevin G. Nugent
IPC分类号： A61N1/362 , A61N1/365
CPC分类号： A61N1/36542 , A61N1/3627
摘要： Hemodynamic performance of the heart as a pump is optimized by using an accelerometer and signal processing circuitry to measure total acoustic noise (TAN) over predetermined time periods when a pacemaker is made to function in a variety of modes. By detecting the particular mode associated with minimum TAN, the optimum pacing mode is arrived at.
摘要翻译：心脏作为泵的血液动力学性能通过使用加速度计和信号处理电路在起搏器在各种模式下起作用的预定时间段内测量总声学噪声（TAN）而被优化。通过检测与最小TAN相关联的特定模式，可以得到最佳起搏模式。

76. 发明授权

US5417717A Implantable cardiac function monitor and stimulator for diagnosis and therapy delivery 失效
标题翻译：可植入的心脏功能监测和刺激器用于诊断和治疗
公开(公告)号：US5417717A
公开(公告)日：1995-05-23
申请号：US243069
申请日：1994-05-16
申请人： Rodney W. Salo , Bruce A. Tockman , Morton M. Mower
发明人： Rodney W. Salo , Bruce A. Tockman , Morton M. Mower
IPC分类号： A61M5/172 , A61N1/36 , A61N1/362 , A61N1/365
CPC分类号： A61N1/36042 , A61N1/36585 , A61M5/1723 , A61N1/3627
摘要： An implantable monitor/stimulator is disclosed that monitors and assesses indices of cardiac function, including the strength and timing of cardiac contraction, then automatically executes a physician-selected mode of therapy. It accomplishes this by assessing impedance, electrocardiogram, and/or pressure measurements, then calculating various cardiac parameters. The results of these calculations may be stored within the device, telemetered to an external monitor or display and/or may be used by the physician to determine the mode of therapy to be chosen. If indicated, therapy is administered by the device itself or by telemetering control signals to various peripheral devices for the purpose of enhancing either contraction or relaxation of the heart. The cardiac parameters that are calculated all provide an assessment of level of cardiac function by monitoring changes in ventricular filling and ejection or by calculating isovolumic phase indices of heart contraction. Examples of such parameters are ejection fraction, cardiac output, stroke work, and/or various pressure-volume relationships. These parameters determine the mode of therapy that will be selected by a physician. Choices of therapy include several forms of pacing of cardiac or skeletal muscle, and telemetry to implanted or external units for drug infusion or for monitoring by a central data system.
摘要翻译：公开了一种监测和评估心脏功能指标（包括心脏收缩的强度和时间）的植入式监测器/刺激器，然后自动执行医师选择的治疗模式。它通过评估阻抗，心电图和/或压力测量，然后计算各种心脏参数来实现。这些计算的结果可以存储在设备内，遥测到外部监视器或显示器，和/或可被医师用来确定要选择的治疗方式。如果指示，治疗由装置本身施用或通过将控制信号遥测到各种外围装置，以增强心脏的收缩或放松的目的。计算的心脏参数都通过监测心室充盈和排出的变化或通过计算心脏收缩的等容性相位指数来提供心脏功能水平的评估。这些参数的实例是射血分数，心输出量，中风工作量和/或各种压力 - 体积关系。这些参数决定了医生选择的治疗方式。治疗选择包括心脏或骨骼肌的几种形式的起搏，以及用于药物输注或由中央数据系统监测的植入或外部单元的遥测。

77. 发明授权

US4773401A Physiologic control of pacemaker rate using pre-ejection interval as the controlling parameter 失效
标题翻译：使用预喷射间隔作为控制参数对起搏器的生理控制
公开(公告)号：US4773401A
公开(公告)日：1988-09-27
申请号：US87869
申请日：1987-08-21
申请人： Brian P. Citak , Michael W. Dooley , Arthur L. Olive , Brian D. Pederson , Renold J. Russie , Rodney W. Salo , William L. Zimmer
发明人： Brian P. Citak , Michael W. Dooley , Arthur L. Olive , Brian D. Pederson , Renold J. Russie , Rodney W. Salo , William L. Zimmer
IPC分类号： A61N1/365 , A61N1/30
CPC分类号： A61N1/36521 , A61N1/36514
摘要： A multi-pole pacing/sensing lead is used to measure the instantaneous impedance in the right ventricle of a patient's heart. The resulting impedance waveform is signal processed to obtain a measure of the time interval beginning with the occurrence of a paced beat or a spontaneous QRS complex (systole marker) and ending with the point where the impedance versus time signal crosses the zero axis in the positive direction following the paced or spontaneous QRS complex initiating the interval or some other predetermined point along the positive-going waveform. The resulting time interval is inversely proportional to the contractility of the heart and is found to decrease with exercise and the introduction of catecholamines. Thus, it can be used as a control parameter for a demand-type cardiac pacemaker. A means for obviating changes in pacing rate due to long-term drift in the impedance sensing circuitry is also disclosed.
摘要翻译：多极起搏/感应引线用于测量患者心脏右心室的瞬时阻抗。对所得到的阻抗波形进行信号处理，以获得从出现节奏搏动或自发QRS复合（收缩标记）开始的时间间隔的测量结果，并以阻抗对时间信号穿过正轴的零轴的点结束沿着起搏或自发的QRS复合物沿着正向波形发起间隔或一些其它预定点。所产生的时间间隔与心脏的收缩力成反比，并且发现随着运动和引入儿茶酚胺而减少。因此，它可以用作需求型心脏起搏器的控制参数。还公开了一种用于消除由于阻抗感测电路中的长期漂移引起的起搏速率变化的方法。

78. 发明授权

US09002452B2 Electrical therapy for diastolic dysfunction 有权
标题翻译：电疗法用于舒张功能障碍
公开(公告)号：US09002452B2
公开(公告)日：2015-04-07
申请号：US10703398
申请日：2003-11-07
申请人： Rodney W. Salo , Matthew Salo
发明人： Rodney W. Salo , Matthew Salo
IPC分类号： A61N1/365 , A61N1/362
CPC分类号： A61N1/3627 , A61N1/36514
摘要： Pacing pulses are delivered to one or more cardiac regions to improve diastolic performance in patients having diastolic dysfunction and/or heart failure. A cardiac pacing system executes a pacing algorithm using a parameter indicative of the diastolic performance as an input. The pacing pulses excite the one or more cardiac regions to redistribute the loading on the ventricular wall during diastole, thereby improving the diastolic performance by lowering the degree of cardiac wall motion dyssynchrony associated with diastolic dysfunction.
摘要翻译：将起搏脉冲输送到一个或多个心脏区域以改善具有舒张功能障碍和/或心力衰竭的患者的舒张性能。心脏起搏系统使用表示舒张性能的参数作为输入来执行起搏算法。起搏脉冲激发一个或多个心脏区域以在舒张期期间重新分布心室壁上的负荷，从而通过降低与舒张功能障碍相关的心脏壁运动不同步的程度来改善舒张性能。

79. 发明授权

US08103326B2 Device for monitoring fluid status 有权
标题翻译：用于监测流体状态的装置
公开(公告)号：US08103326B2
公开(公告)日：2012-01-24
申请号：US12098644
申请日：2008-04-07
申请人： Robert J. Sweeney , Julio C. Spinelli , Rodney W. Salo
发明人： Robert J. Sweeney , Julio C. Spinelli , Rodney W. Salo
IPC分类号： A61B5/00
CPC分类号： A61B5/0538 , A61B5/053 , A61B5/14535 , A61N1/36521
摘要： A technique for determining a patient's hematocrit by an electrical impedance measurement is described. An implantable device may be configured to utilize the technique in order to assess a cardiac patient's fluid status. In order to determine the hematocrit, the electrical impedance of the blood is measured and mapped by a mapping function to a corresponding hematocrit value.
摘要翻译：描述了通过电阻抗测量来确定患者的血细胞比容的技术。可植入装置可被配置为利用该技术来评估心脏病人的流体状态。为了确定血细胞比容，测量血液的电阻抗并通过映射函数映射到相应的血细胞比容值。

80. 发明授权

US08090442B2 Apparatus and method for spatially and temporally distributing cardiac electrical stimulation 有权
标题翻译：空间和时间分布心脏电刺激的装置和方法
公开(公告)号：US08090442B2
公开(公告)日：2012-01-03
申请号：US11931718
申请日：2007-10-31
申请人： Rodney W. Salo , Julio C. Spinelli , Bruce H. KenKnight
发明人： Rodney W. Salo , Julio C. Spinelli , Bruce H. KenKnight
IPC分类号： A61N1/368
CPC分类号： A61N1/368 , A61N1/3622 , A61N1/3627
摘要： A cardiac electro-stimulatory device and method for operating same in which stimulation pulses are distributed among a plurality of electrodes fixed at different sites of the myocardium in order to reduce myocardial hypertrophy brought about by repeated pacing at a single site and/or increase myocardial contractility. In order to spatially and temporally distribute the stimulation, the pulses are delivered through a switchable pulse output configuration during a single cardiac cycle, with each configuration comprising one or more electrodes fixed to different sites in the myocardium.
摘要翻译：一种心脏电刺激装置及其操作方法，其中刺激脉冲分布在固定在心肌不同部位的多个电极之间，以便通过在单个部位重复起搏而引起的心肌肥大和/或增加心肌收缩力。为了空间和时间地分布刺激，脉冲在单个心动周期期间通过可切换的脉冲输出配置递送，每个配置包括一个或多个电极固定在心肌中的不同部位。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式