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    • 71. 发明授权
    • Method for manufacturing ink jet recording head
    • 制造喷墨记录头的方法
    • US06668453B1
    • 2003-12-30
    • US08683761
    • 1996-07-17
    • Makoto Shibata
    • Makoto Shibata
    • B23P1500
    • B29C45/14467B29C35/02B29C45/0055B29C2793/009B29L2031/767B41J2/1603B41J2/1629B41J2/1631B41J2/1632B41J2/1635B41J2/1637B41J2/1646Y10T29/49401
    • A method for manufacturing an ink jet recording head comprising a discharging orifice for discharging an ink, a discharge pressure generating element for generating energy for ink discharge, and an ink flow path communicating with the discharging orifice, said method comprising a step of preparing a first substrate provided with the discharge pressure generating element, a step of forming a removable pattern material for forming the ink flow path on the first substrate, a step of preparing a second substrate provided with an ink feed opening for feeding the ink to the ink flow papth, a step of fixing the first substrate and the second substrate with the interposition of a predetermined space via the pattern material, a step of injecting a resin for forming an ink flow path wall into a space between the first substrate and the second substrate, a step of curing the resin, a step of simultaneously cutting the first substrate, the second substrate and the cured resin to divide them into individual ink jet recording heads, and a step of removing the pattern material to form the ink flow path, wherein an injection opening is arranged in the vicinity of the portion for the ink flow path of the first substrate, and the resin is injected through the injection opening.
    • 一种用于制造喷墨记录头的方法,该喷墨记录头包括用于排出墨的排出口,用于产生用于排墨的能量的排出压力产生元件以及与排放孔连通的墨流路,所述方法包括以下步骤: 设置有排出压力产生元件的基板,在第一基板上形成用于形成油墨流路的可移除图案材料的步骤,准备第二基板的步骤,该第二基板设置有用于将油墨供给到墨水流动步骤 经由所述图案材料固定所述第一基板和所述第二基板的步骤,将用于形成墨流路壁的树脂注入到所述第一基板和所述第二基板之间的空间中的步骤, 固化树脂的步骤,同时切割第一基板,第二基板和固化树脂以将它们分成i的步骤 各个喷墨记录头,以及去除图案材料以形成油墨流路的步骤,其中在第一基板的油墨流动路径部分附近设置有注入口,并且树脂通过 注射开口。
    • 72. 发明授权
    • Benzothiazine derivative
    • 苯并噻嗪衍生物
    • US06664251B2
    • 2003-12-16
    • US09955416
    • 2001-09-19
    • Akira MizunoMakoto ShibataTomoe IwamoriNorio Inomata
    • Akira MizunoMakoto ShibataTomoe IwamoriNorio Inomata
    • C07D27916
    • C07D275/06C07D279/02C07D417/06C07D513/10
    • Disclosed are benzothiazine derivatives represented by the following formula (I): wherein the dashed line indicates the presence or absence of a bond; Z represents one of the following groups: in which R1 and R2 individually represent alkyl, aralkyl or the like, R3 represents H, alkyl or the like, R4 represents H, aralkyl or the like, X1, X2 and X3 individually represent O or S, and G represents substituted or unsubstituted ethylene, trimethylene or the like; Q1 and Q2 individually represent H, OH, halogen, alkoxy or the like; A represents alkylene, alkenylene or the like; Y represents CH, C═ or N; when Y is CH, m stands for 0 or 1, n stands for 1 or 2, B represents O, S, carbonyl or the like, when Y is C═, m stands for 1, n stands for 1 or 2, B represents: in which the double bond is linked to Y, R6 represents substituted or unsubstituted aryl or the like; when Y is N, m stands for 0 or 1, n stands for 2 or 3 and B represents carbonyl, sulfonyl or the like, E1 and E2 individually represent H or lower alkyl; and D represents an aromatic hydrocarbon group or an aromatic heterocyclic group; and salts thereof. The benzothiazine derivatives (I) and their salts according to the present invention have strong serotonin-2 blocking action, have excellent selectivity to this action against &agr;1 blocking action and have high safety. Accordingly, the present invention has made it possible to provide pharmaceuticals making use of antagonistic action against serotonin-2 receptors, for example, therapeutics for various circulatory diseases such as ishemic heart diseases, cerebrovascular disturbances and peripheral circulatory disturbances.
    • 公开了由下式(I)表示的苯并噻嗪衍生物:其中虚线表示存在或不存在键; Z表示以下基团之一:其中R1和R2分别表示烷基,芳烷基等,R3表示H,烷基等,R4表示H,芳烷基等,X1,X2和X3各自表示O或S ,G表示取代或未取代的乙烯,三亚甲基等; Q1和Q2各自表示H,OH,卤素,烷氧基等; A表示亚烷基,亚烯基等; Y表示CH,C =或N; 当Y是CH时,m代表0或1,n代表1或2,B代表O,S,羰基等,当Y是C =,m代表1,n代表1或2,B代表 :其中双键与Y连接,R​​6表示取代或未取代的芳基等; 当Y为N时,m代表0或1,n代表2或3,B代表羰基,磺酰基等,E1和E2分别代表H或低级烷基; D表示芳香族烃基或芳香族杂环基; 其盐。根据本发明的苯并噻嗪衍生物(I)及其盐具有强的5-羟色胺-2阻断作用,对该作用对α1阻断作用具有优异的选择性并具有高安全性。 因此,本发明使得可以提供利用针对5-羟色胺-2受体的拮抗作用的药物,例如用于各种循环系统疾病如血液性心脏病,脑血管障碍和外周循环障碍的治疗剂。
    • 73. 发明授权
    • Pyrroloazepine compounds
    • 吡咯并氮化合物
    • US06211362B1
    • 2001-04-03
    • US09640010
    • 2000-08-17
    • Akira MizunoMakoto ShibataTomoe KameiNorio Inomata
    • Akira MizunoMakoto ShibataTomoe KameiNorio Inomata
    • C07D48704
    • C07D207/416C07D487/04
    • Disclosed are pyrroloazepine compounds and their salts. These pyrroloazepine compounds are represented by the following formula: wherein the dashed line indicates the presence or absence of a bond; and, when the bond is present, Z2 is not present and Z1 is H but, when the bond is absent, Z1 and Z2 are both Hs; Z1 is H and Z2 is OH; Z1 and Z2 are both SR5s in which R5 is alkyl, aralkyl or aryl; or Z1 and Z2 are combined together to represent O, NOR6 in which R6 is H, alkyl, aralkyl or aryl, or C2-C3 alkylenedithio; R is H, alkyl, cycloalkyl, cycloalkyl-alkyl or aralkyl; and the ring P is a specific pyrrole ring. These pyrroloazepine compounds and salts are effective as preventives or therapeutics for general circulatory diseases such as hypertension, heart failure, ischemic hear diseases, cerebrovascular disturbances and peripheral circulatory disturbances. Their production processes are also disclosed.
    • 公开了吡咯并氮化合物及其盐。 这些吡咯并氮化合物由下式表示:其中虚线表示存在或不存在键; 当存在键时,Z 2不存在且Z1为H,但不存在键时,Z 1和Z 2均为Hs; Z1是H,Z2是OH; Z 1和Z 2都是SR 5,其中R 5是烷基,芳烷基或芳基; 或Z 1和Z 2组合在一起代表O,NOR6,其中R 6是H,烷基,芳烷基或芳基,或C 2 -C 3亚烷基二硫基; R是H,烷基,环烷基,环烷基 - 烷基或芳烷基; 环P是特定的吡咯环。 这些吡咯并氮化合物和盐可用作一般循环系统疾病如高血压,心力衰竭,缺血性听觉疾病,脑血管障碍和外周循环障碍的预防剂或治疗剂。 他们的生产过程也被披露。
    • 74. 发明授权
    • Liquid jet recording head
    • 液体喷射记录头
    • US5992983A
    • 1999-11-30
    • US473987
    • 1995-06-07
    • Hiroto TakahashiMasami IkedaHiroto MatsudaMakoto Shibata
    • Hiroto TakahashiMasami IkedaHiroto MatsudaMakoto Shibata
    • B41J2/14B41J2/16B41J2/05
    • B41J2/14129B41J2/1604B41J2/1623B41J2/1631B41J2/164B41J2/1642B41J2/1645B41J2/1646B41J2202/03
    • A liquid jet recording head for discharging liquid droplets onto a recording medium includes a support, heat-generating resistance layer provided on the support for generating heat energy to discharge the liquid droplets, a pair of electrodes electrically connected to the heat-generating resistance layer, and heat-generating sections each serving as a portion for generating the heat energy, each head generating section comprising the heat-generating resistance layer sandwiched by the pair of electrodes. Plural discharge openings serve to discharge liquid droplets, a liquid chamber houses liquid, and there are plural liquid paths, each liquid path having an associated heat generating section, and communicating with an associated discharge opening and with the liquid chamber to supply liquid to the associated discharge opening from the liquid chamber. An layer on the support protects the heat-generating resistance layer and pair of electrodes, and the upper layer has an organic resin layer of organic material, and this organic resin layer is formed only on a whole region upstream of the heat-generating sections on the support in a liquid supply direction.
    • 用于将液滴喷射到记录介质上的液体喷射记录头包括支撑体,设置在支撑体上的产生热能以排出液滴的发热电阻层,与发热电阻层电连接的一对电极, 以及每个用作产生热能的部分的发热部,每个头部产生部分包括被一对电极夹在该发热电阻层之间。 多个排放口用于排出液滴,液体腔容纳液体,并且存在多个液体通道,每个液体通道具有相关联的发热部分,并且与相关联的排出口和液体室连通以将液体供应到相关联的 从液体室排放开口。 支架上的层保护发热电阻层和电极对,上层具有有机材料的有机树脂层,该有机树脂层仅形成在发热部分上游的整个区域上 支撑液体供应方向。