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71. 发明申请

US20080249583A1 THERAPY CONTROL BASED ON THE RATE OF CHANGE OF INTRACARDIAC IMPEDANCE 有权
标题翻译：基于内皮抑素变化率的治疗控制
公开(公告)号：US20080249583A1
公开(公告)日：2008-10-09
申请号：US12105219
申请日：2008-04-17
申请人： Rodney W. Salo , Joseph M. Pastore , Jeffrey E. Stahmann , Jesse W. Hartley
发明人： Rodney W. Salo , Joseph M. Pastore , Jeffrey E. Stahmann , Jesse W. Hartley
IPC分类号： A61N1/368
CPC分类号： A61N1/36521 , A61N1/30
摘要： A system comprising a medical device that includes an impedance measurement circuit adapted to be coupled to implantable electrodes to obtain an intracardiac impedance signal between electrodes, a therapy circuit operable to deliver a therapy to a subject, and a controller circuit coupled to the impedance measurement circuit and the therapy circuit. The controller circuit determines a time rate of change of the intracardiac impedance signal and adjusts at least one parameter related to therapy in a manner that alters the rate of change.
摘要翻译：一种包括医疗装置的系统，该医疗装置包括阻抗测量电路，该阻抗测量电路适于耦合到可植入电极以获得电极之间的心内阻抗信号，可操作以将治疗递送给受试者的治疗电路，以及耦合到所述阻抗测量电路和治疗电路。控制器电路确定心内阻抗信号的时间变化率，并且以改变变化率的方式调节与治疗相关的至少一个参数。

72. 发明申请

US20080167692A1 METHOD AND APPARATUS FOR DELIVERING DEFIBRILLATION SHOCK THERAPY WHILE REDUCING ELECTRICAL DISPERSION DUE TO VENTRICULAR CONDUCTION DISORDER 有权
标题翻译：用于在减轻因静脉导管障碍引起的电解液的情况下提供减震手术的方法和装置
公开(公告)号：US20080167692A1
公开(公告)日：2008-07-10
申请号：US12051997
申请日：2008-03-20
申请人： Jeffrey E. Stahmann , Jesse W. Hartley , Steven D. Girouard
发明人： Jeffrey E. Stahmann , Jesse W. Hartley , Steven D. Girouard
IPC分类号： A61N1/362
CPC分类号： A61N1/3622 , A61N1/3627 , A61N1/3684 , A61N1/3962
摘要： A method and device for delivering defibrillation shock therapy in patients having an inter-ventricular conduction disorder is presented. Ventricular resynchronization therapy is employed to reduce the dispersion of ventricular depolarization which takes place due to the conduction disorder and reduces the safety margin of shocks delivered synchronously with ventricular beats. The method may be employed in the treatment of atrial or ventricular tachyarrhythmias.
摘要翻译：提出了一种用于在患有心室间传导障碍的患者中递送除颤休克疗法的方法和装置。采用心室再同步治疗来减少由于传导障碍引起的心室去极化的分散，降低与心室搏动同步传递的休克的安全余量。该方法可用于治疗心房或室性快速性心律失常。

73. 发明授权

US07349734B2 Method and apparatus for delivering defibrillation shock therapy while reducing electrical dispersion due to ventricular conduction disorder 失效
标题翻译：用于递送除颤休克疗法同时减少由于心室传导障碍引起的电离散的方法和装置
公开(公告)号：US07349734B2
公开(公告)日：2008-03-25
申请号：US10746856
申请日：2003-12-24
申请人： Jeffrey E. Stahmann , Jesse W. Hartley , Steven D. Girouard
发明人： Jeffrey E. Stahmann , Jesse W. Hartley , Steven D. Girouard
IPC分类号： A61N1/00
CPC分类号： A61N1/3622 , A61N1/3627 , A61N1/3684 , A61N1/3962
摘要： A method and device for delivering defibrillation shock therapy in patients having an inter-ventricular conduction disorder is presented. Ventricular resynchronization therapy is employed to reduce the dispersion of ventricular depolarization which takes place due to the conduction disorder and reduces the safety margin of shocks delivered synchronously with ventricular beats. The method may be employed in the treatment of atrial or ventricular tachyarrhythmias.
摘要翻译：提出了一种用于在患有心室间传导障碍的患者中递送除颤休克疗法的方法和装置。采用心室再同步治疗来减少由于传导障碍引起的心室去极化的分散，降低与心室搏动同步传递的休克的安全余量。该方法可用于治疗心房或室性快速性心律失常。

74. 发明授权

US08660638B2 Syncope logbook and method of using same 有权
标题翻译：晕厥日志及其使用方法
公开(公告)号：US08660638B2
公开(公告)日：2014-02-25
申请号：US12616536
申请日：2009-11-11
申请人： Jeffrey E. Stahmann , John D. Hatlestad , Jesse W. Hartley , Avram Scheiner
发明人： Jeffrey E. Stahmann , John D. Hatlestad , Jesse W. Hartley , Avram Scheiner
IPC分类号： A61B5/0402
CPC分类号： A61B5/02028 , A61B5/0031 , A61B5/0205 , A61B5/0215 , A61B5/02405 , A61B5/0402 , A61B5/0476 , A61B5/11 , A61B5/1116 , A61B5/145 , A61B5/14532 , A61B5/14546 , A61N1/362 , A61N1/37247 , G06F19/00 , G06F19/3418 , G06F19/3481 , G16H40/63
摘要： Methods and systems are directed to acquiring and organizing information associated with at least one syncope event. A syncope event may be a suspected syncope event, a verified syncope event or a syncope event that is suspected and verified. Automated processes are used to collect information associated with at least one syncope event and organize the information as a syncope log entry. At least one of acquiring the information and organizing the information is performed at least in part implantably.
摘要翻译：方法和系统旨在获取和组织与至少一个晕厥事件相关联的信息。晕厥事件可能是疑似晕厥事件，经过验证的晕厥事件或怀疑和验证的晕厥事件。自动进程用于收集与至少一个晕厥事件相关的信息，并将该信息组织为晕厥日志条目。至少部分地可植入地执行获取信息和组织信息中的至少一个。

75. 发明申请

US20120029588A1 METHOD AND APPARATUS FOR CONTROL OF CARDIAC THERAPY USING NON-INVASIVE HEMODYNAMIC SENSOR 有权
标题翻译：使用非侵入式血液动力传感器控制心脏病治疗的方法和装置
公开(公告)号：US20120029588A1
公开(公告)日：2012-02-02
申请号：US13273108
申请日：2011-10-13
申请人： Andrew P. Kramer , Joseph M. Pastore , Jeffrey E. Stahmann , Rodney W. Salo , Jesse W. Hartley
发明人： Andrew P. Kramer , Joseph M. Pastore , Jeffrey E. Stahmann , Rodney W. Salo , Jesse W. Hartley
IPC分类号： A61N1/365
CPC分类号： A61N1/36557 , A61B5/6816 , A61B5/6826 , A61B5/6829 , A61B5/6838 , A61N1/36114 , A61N1/36564
摘要： A cardiac rhythm management (CRM) system includes a non-invasive hemodynamic sensing device and an implantable medical device to sense a hemodynamic signal and derive one or more cardiac performance parameters from the hemodynamic signal. The non-invasive hemodynamic sensing device includes at least a portion configured for external attachment to a body in which the implantable medical device is implanted. The one or more cardiac performance parameters are used for various diagnostic, monitoring, and therapy control purposes.
摘要翻译：心律管理（CRM）系统包括非侵入性血液动力学感测装置和可植入医疗装置，用于感测血液动力学信号并从血流动力学信号导出一个或多个心脏性能参数。非侵入式血流动力学检测装置包括至少一部分，其构造成用于外部附接到其中植入可植入医疗装置的主体。一个或多个心脏性能参数用于各种诊断，监测和治疗控制目的。

76. 发明授权

US08027719B2 Method and apparatus for delivering defibrillation shock therapy while reducing electrical dispersion due to ventricular conduction disorder 有权
标题翻译：用于递送除颤休克疗法同时减少由于心室传导障碍引起的电离散的方法和装置
公开(公告)号：US08027719B2
公开(公告)日：2011-09-27
申请号：US12051997
申请日：2008-03-20
申请人： Jeffrey E. Stahmann , Jesse W. Hartley , Steven D. Girouard
发明人： Jeffrey E. Stahmann , Jesse W. Hartley , Steven D. Girouard
IPC分类号： A61N1/00
CPC分类号： A61N1/3622 , A61N1/3627 , A61N1/3684 , A61N1/3962
摘要： A method and device for delivering defibrillation shock therapy in patients having an inter-ventricular conduction disorder is presented. Ventricular resynchronization therapy is employed to reduce the dispersion of ventricular depolarization which takes place due to the conduction disorder and reduces the safety margin of shocks delivered synchronously with ventricular beats. The method may be employed in the treatment of atrial or ventricular tachyarrhythmias.
摘要翻译：提出了一种用于在患有心室间传导障碍的患者中递送除颤休克疗法的方法和装置。采用心室再同步治疗来减少由于传导障碍引起的心室去极化的分散，降低与心室搏动同步传递的休克的安全余量。该方法可用于治疗心房或室性快速性心律失常。

77. 发明授权

US07979115B2 Detection of pleural effusion using transthoracic impedance 有权
标题翻译：使用经胸阻塞检测胸腔积液
公开(公告)号：US07979115B2
公开(公告)日：2011-07-12
申请号：US11972405
申请日：2008-01-10
申请人： Jeffrey E. Stahmann , John Hatlestad , Jesse W. Hartley , Richard Fogoros
发明人： Jeffrey E. Stahmann , John Hatlestad , Jesse W. Hartley , Richard Fogoros
IPC分类号： A61B5/05
CPC分类号： A61B5/0205 , A61B5/0031 , A61B5/0535 , A61B5/1116 , A61B5/4869 , A61N1/36521 , A61N1/36535
摘要： This patent document discusses systems, devices, and methods for increasing a sensitivity or specificity of thoracic fluid detection in a subject and differentiating between pleural effusion and pulmonary edema. In one example, a thoracic impedance measurement circuit senses a thoracic impedance signal. In another example, a processor receives the thoracic impedance signal and determines whether such thoracic impedance signal is “significant.” A significant thoracic impedance signal indicates the presence of thoracic fluid and may be recognized by comparing the thoracic impedance signal (or variation thereof) to a thoracic impedance threshold. When a significant thoracic impedance signal is recognized, the processor is adapted to detect one or both of: a pleural effusion indication and a pulmonary edema indication using one or a combination of: physiologic information, patient symptom information, and posture information. In another example, the thoracic impedance threshold is adjusted using such physiologic, patient symptom, or posture information.
摘要翻译：该专利文献讨论了用于增加受试者胸部液体检测的敏感性或特异性并区分胸腔积液和肺水肿的系统，装置和方法。在一个示例中，胸部阻抗测量电路感测胸部阻抗信号。在另一示例中，处理器接收胸部阻抗信号并确定这种胸部阻抗信号是否“显着”。显着的胸部阻抗信号表示胸腔存在，并且可以通过将胸部阻抗信号（或其变化）与胸阻抗阈值。当识别出显着的胸部阻抗信号时，处理器适合于使用生理信息，患者症状信息和姿势信息中的一个或组合来检测胸腔积液指示和肺水肿指示之一或两者。在另一个例子中，使用这种生理，患者症状或姿势信息来调整胸阻抗阈值。

78. 发明申请

US20110144526A1 ENHANCEMENTS TO THE DETECTION OF PULMONARY EDEMA WHEN USING TRANSTHORACIC IMPEDANCE 有权
标题翻译：使用潮热阻力时检测脉搏电流的增强
公开(公告)号：US20110144526A1
公开(公告)日：2011-06-16
申请号：US13033081
申请日：2011-02-23
申请人： Jeffrey E. Stahmann , John Hatlestad , Jesse W. Hartley
发明人： Jeffrey E. Stahmann , John Hatlestad , Jesse W. Hartley
IPC分类号： A61B5/053
CPC分类号： A61B5/0537 , A61B5/0002 , A61B5/0538 , A61B5/4869 , A61B5/4878
摘要： This patent document discusses, among other things, systems, devices, and methods for enhancing detection of pulmonary edema using, in addition to thoracic impedance, one or a combination of: physiologic information about a subject, at least one statistical parameter, a user-programmable detection level, at least one parameter associated with a previous pulmonary edema event, and patient symptom information about the subject. In one example, a (base) thoracic impedance threshold is modified to an adjusted thoracic impedance threshold. The adjusted thoracic impedance threshold provides an increased sensitivity of pulmonary edema detection as compared to the base thoracic impedance threshold. In another example, an alert is provided to a subject, a caregiver, or other user based on a pulmonary edema indication determined by the present systems, devices, and methods. In a further example, a therapy (provided to the subject) is adjusted or initiated in response to the pulmonary edema indication.
摘要翻译：该专利文献尤其涉及用于增强肺水肿检测的系统，装置和方法，除胸部阻抗之外，还包括以下之一或组合：关于受试者的生理信息，至少一个统计参数，可编程检测水平，与先前的肺水肿事件相关联的至少一个参数，以及关于受试者的患者症状信息。在一个示例中，（基底）胸部阻抗阈值被修改为经调整的胸部阻抗阈值。与基础胸廓阻抗阈值相比，经调整的胸廓阻抗阈值提供了肺水肿检测的灵敏度增加。在另一示例中，基于由本系统，设备和方法确定的肺水肿指示，向受检者，照顾者或其他用户提供警报。在另一个实例中，响应于肺水肿指示调整或启动治疗（提供给受试者）。

79. 发明授权

US07742813B2 Minimizing hemodynamic compromise during post-mi remodeling control pacing 有权
标题翻译：最小化血液动力学妥协在后重建控制起搏
公开(公告)号：US07742813B2
公开(公告)日：2010-06-22
申请号：US11276741
申请日：2006-03-13
申请人： Joseph M. Pastore , Rodney W. Salo , Jesse W. Hartley , Andrew P. Kramer , Jeffrey E. Stahmann
发明人： Joseph M. Pastore , Rodney W. Salo , Jesse W. Hartley , Andrew P. Kramer , Jeffrey E. Stahmann
IPC分类号： A61N1/368
CPC分类号： A61N1/3627 , A61N1/36521 , A61N1/3684
摘要： A method and device for delivering pre-excitation pacing to prevent or reduce cardiac remodeling following a myocardial infarction is described. The pre-excitation pacing is modulated in accordance with an assessment of cardiac function in order to balance the beneficial effects of stress reduction with hemodynamic compromise.
摘要翻译：描述了用于递送预激发起搏以预防或减少心肌梗塞后的心脏重塑的方法和装置。根据心脏功能的评估调节预激励起搏，以平衡应力减少与血液动力学妥协的有益效果。

80. 发明申请

US20100056929A1 Syncope Logbook and Method of Using Same 有权
标题翻译：晕厥日志和使用方法
公开(公告)号：US20100056929A1
公开(公告)日：2010-03-04
申请号：US12616536
申请日：2009-11-11
申请人： Jeffrey E. Stahmann , John D. Hatlestad , Jesse W. Hartley , Avram Scheiner
发明人： Jeffrey E. Stahmann , John D. Hatlestad , Jesse W. Hartley , Avram Scheiner
IPC分类号： A61B5/0205 , A61B5/00 , A61B5/02 , A61B5/08
CPC分类号： A61B5/02028 , A61B5/0031 , A61B5/0205 , A61B5/0215 , A61B5/02405 , A61B5/0402 , A61B5/0476 , A61B5/11 , A61B5/1116 , A61B5/145 , A61B5/14532 , A61B5/14546 , A61N1/362 , A61N1/37247 , G06F19/00 , G06F19/3418 , G06F19/3481 , G16H40/63
摘要： Methods and systems are directed to acquiring and organizing information associated with at least one syncope event. A syncope event may be a suspected syncope event, a verified syncope event or a syncope event that is suspected and verified. Automated processes are used to collect information associated with at least one syncope event and organize the information as a syncope log entry. At least one of acquiring the information and organizing the information is performed at least in part implantably.
摘要翻译：方法和系统旨在获取和组织与至少一个晕厥事件相关联的信息。晕厥事件可能是疑似晕厥事件，经过验证的晕厥事件或怀疑和验证的晕厥事件。自动进程用于收集与至少一个晕厥事件相关的信息，并将该信息组织为晕厥日志条目。至少部分地可植入地执行获取信息和组织信息中的至少一个。

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