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71. 发明授权

US07389580B2 Method and apparatus for thin-film battery having ultra-thin electrolyte 有权
标题翻译：具有超薄电解质的薄膜电池的方法和装置
公开(公告)号：US07389580B2
公开(公告)日：2008-06-24
申请号：US11692176
申请日：2007-03-27
申请人： Mark L. Jenson , Victor H. Weiss
发明人： Mark L. Jenson , Victor H. Weiss
IPC分类号： B23P17/00
CPC分类号： H01M10/4264 , A61N1/3787 , C23C14/0031 , C23C14/0676 , C23C14/08 , C23C16/047 , G02F1/13306 , G02F2001/13324 , H01G11/08 , H01G11/26 , H01G11/56 , H01L23/58 , H01L31/073 , H01L31/1828 , H01L2224/16225 , H01L2224/48091 , H01L2224/49109 , H01L2924/09701 , H01L2924/10253 , H01L2924/12044 , H01M2/0207 , H01M2/1066 , H01M2/145 , H01M2/20 , H01M4/0421 , H01M4/0423 , H01M4/0426 , H01M4/1391 , H01M4/1393 , H01M4/1397 , H01M4/382 , H01M4/405 , H01M4/483 , H01M4/581 , H01M4/5825 , H01M4/587 , H01M4/8885 , H01M4/9016 , H01M6/185 , H01M6/186 , H01M6/188 , H01M6/40 , H01M6/42 , H01M8/1007 , H01M8/1286 , H01M10/0436 , H01M10/0472 , H01M10/052 , H01M10/0525 , H01M10/0562 , H01M10/058 , H01M10/0585 , H01M10/42 , H01M10/425 , H01M10/4257 , H01M10/44 , H01M10/46 , H01M10/465 , H01M14/00 , H01M14/005 , H01M2002/0205 , H01M2004/021 , H01M2008/1293 , H04M1/0262 , H05K1/16 , Y02E10/543 , Y02E60/122 , Y02E60/13 , Y02P70/521 , Y02P70/54 , Y10S117/902 , Y10T29/49108 , Y10T29/49114 , Y10T29/49115 , Y10T29/4913 , Y10T29/5313 , Y10T29/53135 , H01L2924/00014 , H01L2924/00
摘要： A method and system for fabricating solid-state energy-storage devices including fabrication films for devices without an anneal step. A film of an energy-storage device is fabricated by depositing a first material layer to a location on a substrate. Energy is supplied directly to the material forming the film. The energy can be in the form of energized ions of a second material. Supplying energy directly to the material and/or the film being deposited assists in controlling the growth and stoichiometry of the film. The method allows for the fabrication of ultrathin films such as electrolyte films and dielectric films.
摘要翻译：一种用于制造固态储能装置的方法和系统，其包括用于没有退火步骤的装置的制造薄膜。通过将第一材料层沉积到衬底上的位置来制造能量存储装置的膜。能量直接供应到形成薄膜的材料上。能量可以是第二材料的能量离子的形式。向被沉积的材料和/或薄膜直接提供能量有助于控制薄膜的生长和化学计量。该方法允许制造诸如电解质膜和介电膜的超薄膜。

72. 发明授权

US06945951B1 Thrombectomy catheter and system 失效
标题翻译：血栓切除导管及系统
公开(公告)号：US06945951B1
公开(公告)日：2005-09-20
申请号：US09930796
申请日：2001-08-16
申请人： Michael J. Bonnette , John Edward Morris , Steven E. Wiesel , John B. Bridgeman , Debra M. Kozak , Rosemary C. Beaupre , Mark L. Jenson , Cindy M. Setum , Robert C. Dutcher
发明人： Michael J. Bonnette , John Edward Morris , Steven E. Wiesel , John B. Bridgeman , Debra M. Kozak , Rosemary C. Beaupre , Mark L. Jenson , Cindy M. Setum , Robert C. Dutcher
IPC分类号： A61B17/22 , A61B17/32 , A61M1/00 , A61B17/20
CPC分类号： A61B17/32037 , A61B17/3203 , A61M1/0084
摘要： Cross stream thrombectomy catheter and system for fragmentation and removal of thrombus or other material from blood vessels or other body cavities. High velocity saline jets emitted from a toroidal loop jet emanator or other jet emanator in a catheter distal end entrain fluid through inflow orifices, and with flow resistances create a back-pressure which drives cross stream streams through outflow orifices in a radial direction and thence radially and circumferentially to apply normal and drag forces on thrombotic deposits or lesions in the blood vessel or other body cavity, thereby breaking apart and transporting thrombus particles to be entrained through the inflow orifices, whereupon the high velocity jets macerate the thrombus particles which then transit an exhaust lumen or recirculate again via the outflow orifices.
摘要翻译：交叉流血栓切除术导管和用于从血管或其他体腔破裂和去除血栓或其他材料的系统。从导管远端的环形环喷射发生器或其他喷射发射器发射的高速盐水喷射器通过流入孔夹带流体，并且流动阻力产生背压，该背压驱动跨径流通过径向流出孔，并周向地将正常和牵引力施加在血管或其它体腔中的血栓形成沉积物或病变上，从而分离和输送通过流入孔夹带的血栓颗粒，于是高速喷射器将血栓颗粒浸入，排气腔或再次通过外流孔再循环。

73. 发明授权

US06805684B2 Thrombectomy catheter and system 失效
公开(公告)号：US06805684B2
公开(公告)日：2004-10-19
申请号：US09930795
申请日：2001-08-16
申请人： Michael J. Bonnette , John Edward Morris , Steven E. Wiesel , John B. Bridgeman , Debra M. Kozak , Rosemary C. Beaupre , Mark L. Jenson , Cindy M. Setum , Robert C. Dutcher
发明人： Michael J. Bonnette , John Edward Morris , Steven E. Wiesel , John B. Bridgeman , Debra M. Kozak , Rosemary C. Beaupre , Mark L. Jenson , Cindy M. Setum , Robert C. Dutcher
IPC分类号： A61B1720
CPC分类号： A61B17/32037 , A61B17/3203 , A61M1/0084
摘要： Cross stream thrombectomy catheter and system for fragmentation and removal of thrombus or other material from blood vessels or other body cavities. High velocity saline jets emitted from a toroidal loop jet emanator or other jet emanator in a catheter distal end entrain fluid through inflow orifices, and with flow resistances create a back-pressure which drives cross stream streams through outflow orifices in a radial direction and thence radially and circumferentially to apply normal and drag forces on thrombotic deposits or lesions in the blood vessel or other body cavity, thereby breaking apart and transporting thrombus particles to be entrained through the inflow orifices, whereupon the high velocity jets macerate the thrombus particles which then transit an exhaust lumen or recirculate again via the outflow orifices.

74. 发明授权

US06676627B1 Crossflow thrombectomy catheter and system 失效
标题翻译：血栓切除导管及系统
公开(公告)号：US06676627B1
公开(公告)日：2004-01-13
申请号：US09417395
申请日：1999-10-13
申请人： Michael J. Bonnette , John Edward Morris , Steven E. Wiesel , John B. Bridgeman , Debra M. Kozak , Rosemary C. Beaupre , Mark L. Jenson , Cindy M. Setum , Robert C. Dutcher
发明人： Michael J. Bonnette , John Edward Morris , Steven E. Wiesel , John B. Bridgeman , Debra M. Kozak , Rosemary C. Beaupre , Mark L. Jenson , Cindy M. Setum , Robert C. Dutcher
IPC分类号： A61B1720
CPC分类号： A61B17/32037 , A61B17/3203 , A61M1/0084
摘要： Cross stream thrombectomy catheter and system for fragmentation and removal of thrombus or other material from blood vessels or other body cavities. High velocity saline jets emitted from a toroidal loop jet emanator or other jet emanator in a catheter distal end entrain fluid through inflow orifices, and with flow resistances create a back-pressure which drives cross stream streams through outflow orifices in a radial direction and thence radially and circumferentially to apply normal and drag forces on thrombotic deposits or lesions in the blood vessel or other body cavity, thereby breaking apart and transporting thrombus particles to be entrained through the inflow orifices, whereupon the high velocity jets macerate the thrombus particles which then transit an exhaust lumen or recirculate again via the outflow orifices.
摘要翻译：交叉流血栓切除术导管和用于从血管或其他体腔破裂和去除血栓或其他材料的系统。从导管远端的环形环喷射发生器或其他喷射发射器发射的高速盐水喷射器通过流入孔夹带流体，并且流动阻力产生背压，该背压驱动跨径流通过径向流出孔，并周向地将正常和牵引力施加在血管或其它体腔中的血栓形成沉积物或病变上，从而分离和输送通过流入孔夹带的血栓颗粒，于是高速喷射器将血栓颗粒浸入，排气腔或再次通过外流孔再循环。

75. 发明授权

US06558366B1 Thrombectomy method 失效
标题翻译：血栓切除术
公开(公告)号：US06558366B1
公开(公告)日：2003-05-06
申请号：US08349665
申请日：1994-12-05
申请人： William J. Drasler , Robert G. Dutcher , Mark L. Jenson , Joseph M. Thielen , Emmanuil I. Protonotarios
发明人： William J. Drasler , Robert G. Dutcher , Mark L. Jenson , Joseph M. Thielen , Emmanuil I. Protonotarios
IPC分类号： A61M3100
CPC分类号： A61B17/32037 , A61B17/3203
摘要： A method of and apparatus for removing a thrombus deposit from the cardiovascular system of a patient without the need to surgically access the location of the thrombus deposit via a cut-down or other surgical procedure. A catheter is inserted percutaneously into the patient at a convenient location either directly or over a previously positioned guide wire. The distal end of the catheter is advanced under fluoroscopy to the site of the thrombus deposit. A balloon is inflated to stabilize the position of the distal end of the catheter within the center of the vessel lumen. A flexible metal tube conveys an extremely high pressure stream of sterile saline solution to at least one jet at the distal end of the catheter. At least one jet positions the thrombus deposit for emulsification by at least one other jet. By directing the jets toward the orifice of the large evacuation lumen of the catheter, a stagnation pressure is induced which propels the emulsion proximally for disposal. The rate of proximal flow of effluent is metered to correspond with the distal flow of saline solution to ensure minimal local impact on the vasculature at the site of the thrombus deposit.
摘要翻译：一种用于从患者的心血管系统中去除血栓沉积物的方法和装置，而不需要通过切割或其它外科手术手术地进入血栓沉积物的位置。在方便的位置，将导管经皮插入患者中，直接或超过预先定位的导丝。导管的远端在荧光透视下前进到血栓沉积部位。气囊膨胀以将导管的远端的位置稳定在血管内腔的中心内。柔性金属管将非常高压的无菌盐水溶液流传送到导管远端处的至少一个射流。至少一个喷射器通过至少一个其它喷射器将血栓沉积物定位成乳化。通过将射流引导到导管的大抽空腔的孔口，引起停滞压力，其推动乳剂向近端处理。流出物的近端流量计量以与盐溶液的远端流动相对应，以确保对血栓沉积部位的脉管系统的局部影响最小。

76. 发明授权

US6096001A Thrombectomy and tissue removal device 失效
标题翻译：血栓切除术和组织清除装置
公开(公告)号：US6096001A
公开(公告)日：2000-08-01
申请号：US351616
申请日：1994-12-08
申请人： William J. Drasler , Robert G. Dutcher , Mark L. Jenson , Joseph M. Thielen , Emmanuil I. Protonotarios
发明人： William J. Drasler , Robert G. Dutcher , Mark L. Jenson , Joseph M. Thielen , Emmanuil I. Protonotarios
IPC分类号： A61B17/00 , A61B17/22 , A61B17/32 , A61M25/00 , A61B17/20
CPC分类号： A61B17/32037 , A61B17/3203
摘要： A device for removing a thrombus or other tissue deposit from the cardiovascular system, natural or synthetic tubule or cavity found in the human body of a patient without the need to surgically access the location of the thrombus or other tissue deposit via a cut-down or other surgical procedure. A flexible metal or high pressure plastic tube conveys an extremely high pressure stream of sterile saline or other physiologic solution to at least one jet at the distal end of the catheter. At least one jet is directed at the opening of a large exhaust lumen or other target. The jet(s) is responsible for providing a localized negative pressure which entrains tissue into the jet from break-up of the debris. This jet(s) can also provide stagnation pressure in the exhaust lumen which drives the tissue or thrombotic debris out of the exhaust lumen. Operation of the device with tip pressure greater than 500 psi provides this device with the entrainment and exhaust characteristics which contribute to its effectiveness. The rate of exhaust of tissue debris is metered to ensure minimal local impact on the vasculature at the site of the thrombus deposit. A fluid metering means, such as a roller pump, controls the rate of exhaust such that it is in balance with the saline input or can be adjusted to be greater or less than the input. A positive displacement pump operating at steady or pulsatile flow provides the high pressure saline to the tip of the catheter.
摘要翻译：一种用于从心血管系统去除血栓或其他组织沉积物的装置，在患者的人体中发现的天然或合成的小管或腔，而不需要经由切口或外科手术来进入血栓或其他组织沉积物的位置其他外科手术。柔性金属或高压塑料管将非常高压的无菌盐水或其他生理溶液流输送到导管远端处的至少一个射流。至少一个射流指向大排气腔或其他靶的开口。喷气机负责提供局部的负压，其将组织夹带到喷射器中从碎片的分解中。这种喷射器还可以在排气腔中提供停滞压力，其将组织或血栓形成的碎片驱动出排出管腔。尖端压力大于500 psi的设备的操作为该设备提供了有助于其有效性的夹带和排气特性。计量组织碎片的排气速率，以确保局部对血栓沉积部位脉管系统的局部影响最小。诸如辊式泵的流体计量装置控制排气速率，使其与盐水输入平衡，或者可以将其调节为大于或小于输入。以稳定或脉动流动运行的容积式泵向导管的尖端提供高压盐水。

77. 发明授权

US5866217A Silicone composite vascular graft 失效
标题翻译：硅胶复合血管移植
公开(公告)号：US5866217A
公开(公告)日：1999-02-02
申请号：US787227
申请日：1991-11-04
申请人： Mark D. Stenoien , William J. Drasler , Robert J. Scott , Mark L. Jenson
发明人： Mark D. Stenoien , William J. Drasler , Robert J. Scott , Mark L. Jenson
IPC分类号： A61L27/00 , A61F2/06 , A61L27/18 , A61L27/34
CPC分类号： A61L27/18 , A61F2/06 , A61L27/34 , Y10S623/926 , Y10T428/1369 , Y10T428/1376 , Y10T428/1393
摘要： A silicone composite vascular graft especially well suited as an arteriovenous (A-V) graft fistula for dialysis application. The graft has the ability to seal around needle puncture holes without externally applied pressure, excellent anti-kink, anti-crush and strength properties, and a smooth non-porous inner surface which reduces thrombus deposition and enhances the graft wall compliance or elasticity.
摘要翻译：一种硅胶复合血管移植物，特别适合作为动静脉（A-V）移植瘘用于透析应用。移植物能够在没有外部施加压力的情况下密封针穿刺孔，具有优异的抗扭结，抗压溃和强度性能，以及平滑的无孔内表面，其减少血栓沉积并增强移植物壁顺应性或弹性。

78. 发明授权

US09427217B2 Apparatus and method for closing an opening in a blood vessel using memory metal and collagen 有权
标题翻译：使用记忆金属和胶原封闭血管中的开口的装置和方法
公开(公告)号：US09427217B2
公开(公告)日：2016-08-30
申请号：US12026046
申请日：2008-02-05
申请人： William J. Drasler , Tracee Eidenschink , Joseph M. Thielen , Mark L. Jenson , Anu Sadasiva
发明人： William J. Drasler , Tracee Eidenschink , Joseph M. Thielen , Mark L. Jenson , Anu Sadasiva
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B2017/00004 , A61B2017/00637 , A61B2017/00654 , A61B2017/00672 , A61B2017/00867
摘要： An apparatus and method for closing an arteriotomy site are disclosed which may employ the use of a delivery sheath within which is provided an anchoring device formed of memory metal wherein the anchoring device can be extended into the blood vessel itself. The memory metal, has a linear insertion configuration and obtains a non-linear or coiled configuration which can then be pulled back against the inner surface of the blood vessel to form a backstop. A biodegradable plug is then introduced into the tissue tract until it engages the backstop thereby ensuring proper positioning of the biodegradable plug. The anchoring device can then be retracted through the biodegradable plug leaving the arteriotomy site substantially closed with hemostasis being formed therearound.
摘要翻译：公开了一种用于闭合动脉切开术部位的装置和方法，其可以使用输送鞘，其中提供有由记忆金属形成的锚定装置，其中锚固装置可以延伸到血管本身中。记忆金属具有线性插入构型并且获得非线性或盘绕构造，然后可以将其拉回到血管的内表面以形成止回。然后将可生物降解的塞子引入组织管，直到其接合止挡块，从而确保可生物降解的塞子的适当定位。锚定装置然后可以通过可生物降解的塞子缩回，离开动脉切开术位置基本封闭，其中在其周围形成止血。

79. 发明授权

US09192435B2 Renal denervation catheter with cooled RF electrode 有权
标题翻译：肾脏去神经导管与冷却RF电极
公开(公告)号：US09192435B2
公开(公告)日：2015-11-24
申请号：US13302651
申请日：2011-11-22
申请人： Mark L. Jenson
发明人： Mark L. Jenson
IPC分类号： A61B18/18 , A61B18/14 , A61B18/00
CPC分类号： A61B18/1492 , A61B2018/00029 , A61B2018/00083 , A61B2018/0016 , A61B2018/00214 , A61B2018/00279 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/00642 , A61B2018/00648 , A61B2018/00654 , A61B2018/00702 , A61B2018/00791 , A61B2018/00875 , A61B2018/1497
摘要： A catheter has a flexible shaft with a proximal end, a distal end, a lumen arrangement, and a length sufficient to access a patient's renal artery. A conductor arrangement extends between the proximal and distal ends of the shaft. An actuatable helical tip region is provided at the distal end of the shaft, and a bend region is located proximal of the actuatable helical tip region. An electrode arrangement is provided at the actuatable helical tip region and dimensioned for deployment within the target vessel, such as the renal artery. The electrode arrangement is coupled to the conductor arrangement and includes a multiplicity of electrodes positioned on the distal end of the shaft in a spaced relationship. The electrodes have a protruding portion that extends out a distance beyond an outer surface of the distal end of the shaft.
摘要翻译：导管具有柔性轴，其具有近端，远端，管腔布置以及足以进入患者肾动脉的长度。导体布置在轴的近端和远端之间延伸。可致动的螺旋尖端区域设置在轴的远端处，并且弯曲区域位于可致动的螺旋尖端区域的近侧。在可致动的螺旋尖端区域处提供电极布置，并且将其设计成用于展开在目标血管（例如肾动脉）内。电极布置被耦合到导体布置并且包括以间隔开的关系定位在轴的远端上的多个电极。电极具有伸出远离轴的远端的外表面的距离的突出部分。

80. 发明授权

US09155589B2 Sequential activation RF electrode set for renal nerve ablation 有权
标题翻译：顺序激活用于肾神经消融的RF电极
公开(公告)号：US09155589B2
公开(公告)日：2015-10-13
申请号：US13188684
申请日：2011-07-22
申请人： Mark L. Jenson
发明人： Mark L. Jenson
IPC分类号： A61B18/18 , A61B18/14 , A61B18/00 , A61B18/12 , A61B19/00
CPC分类号： A61B18/1492 , A61B2018/0016 , A61B2018/00214 , A61B2018/0022 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00654 , A61B2018/00791 , A61B2018/00875 , A61B2018/00892 , A61B2018/124 , A61B2018/1467 , A61B2090/3966
摘要： A catheter includes a flexible shaft having a length sufficient to access a patient's renal artery. A treatment element at the distal end of the shaft is dimensioned for deployment within the renal artery. The treatment element comprises a radially expandable structure configured to maintain positioning within the renal artery. A multiplicity of electrodes are spaced apart on the treatment element and configured for switchable activation and deactivation in a predetermined sequence to generate overlapping zones of heating directed at perivascular nerves of the renal artery. The overlapping heating zones comprise a distal zone associated with relatively high current densities at a distance from the treatment element sufficient to ablate the perivascular renal nerves and a proximal zone associated with current densities lower than those of the distal zone and insufficient to cause thermal injury to tissue of the renal artery adjacent the treatment element.
摘要翻译：导管包括具有足以接近患者肾动脉的长度的柔性轴。在轴的远端处的治疗元件的尺寸被设计成用于展开在肾动脉内。治疗元件包括构造成保持肾动脉内的定位的径向可扩张结构。多个电极在处理元件上间隔开并且被配置为以预定顺序的可切换的激活和去激活以产生针对肾动脉的血管周围神经的重叠区域。重叠的加热区域包括与处理元件相距一定距离的相当高的电流密度相关的远端区域，其足以消除血管周围肾神经，以及与远端区域的电流密度相关的近端区域，并且不足以引起热损伤肾动脉的组织邻近治疗元件。

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